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VRQNSGIGVLDKAITVLHAVAESPCGLADLCERTDLPRATAHRLAVGLEVHRLLARDGDGLWRLGPALTE LAGHVNDSLLAAGAVVLPRLRELTGESVQLYRREGTSRICVAALEPPAGLRDTVPVGTRLSMTAGSGAKV LLAYADTHTQQAVLPNAKFTDRTLAEVRKRGWAQSAAEREPGVASVSAPVRDGRGAVIAAVSVSGPIDRM GRRPGARWAADLVAAADALTRRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4228 | - | - | 100% (233) | regulatory protein, IclR |
| M. gilvum PYR-GCK | Mflv_3087 | - | 4e-18 | 32.78% (241) | transcriptional regulator, TrmB |
| M. gilvum PYR-GCK | Mflv_0686 | - | 1e-13 | 30.20% (245) | regulatory protein, IclR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3013 | - | 1e-103 | 80.69% (233) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv2989 | - | 1e-103 | 80.69% (233) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3295 | - | 1e-104 | 80.69% (233) | IclR family transcriptional regulator |
| M. marinum M | MMAR_1725 | - | 1e-107 | 82.40% (233) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 1e-101 | 82.73% (220) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2386 | - | 1e-114 | 87.55% (233) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_2042 | - | 1e-112 | 86.27% (233) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1967 | - | 1e-106 | 81.55% (233) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2134 | - | 1e-122 | 93.99% (233) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3013|M.bovis_AF2122/97 MRQHSGIGVLDKAVGVLHAVAESPCGLAELCDRTDLPRATAYRLAAALEV
Rv2989|M.tuberculosis_H37Rv MRQHSGIGVLDKAVGVLHAVAESPCGLAELCDRTDLPRATAYRLAAALEV
MMAR_1725|M.marinum_M MRQDSGIGVIDKAVGLLRATAESPCGLAELCERTGLPRATAYRLAAALEV
MUL_1967|M.ulcerans_Agy99 MRQDSGIGVIDKAVGLLRATAKSPCGLAELCERTGLPRATAYRLAAALEV
MAV_3839|M.avium_104 -------------MGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEV
Mflv_4228|M.gilvum_PYR-GCK MRQNSGIGVLDKAITVLHAVAESPCGLADLCERTDLPRATAHRLAVGLEV
Mvan_2134|M.vanbaalenii_PYR-1 MRQNSGIGVLDKAVTVLHAVAESPCGLADLCERTNLPRATAHRLAVGLEV
MSMEG_2386|M.smegmatis_MC2_155 MRNDSGIGVLDKAVGVLHTVAESPCGLAELCERTGLPRATAHRLAAGLET
TH_2042|M.thermoresistible__bu MRKDSGIGVLDKAVSVLHSVAESPCGLAELCERTGLPRATAHRLAAGLEV
MAB_3295|M.abscessus_ATCC_1997 MRQHSGIGVLDKAVQVLTAIGDSPCGLAELCERTGLPRATAHRLAAGLEV
: :* : ..******:**:** ******:***..**.
Mb3013|M.bovis_AF2122/97 HRLLGRGQDGHWRLGPAITELATHVDDPLLVACAAVLPQLRDATGESVQV
Rv2989|M.tuberculosis_H37Rv HRLLGRGQDGHWRLGPAITELATHVDDPLLVACAAVLPQLRDATGESVQV
MMAR_1725|M.marinum_M HRLLGRDEDGRWGLGPAITELAAHVDDPLLTAGATVLPRLRETTGESVQL
MUL_1967|M.ulcerans_Agy99 HRLLGRDEDGRWGLGPAITELAAHVDDPLLTAGATVLPRLCETTGESVQL
MAV_3839|M.avium_104 HRLLARGDDGRWRLGPAVTELAAHVNDPLLAAGSAVLPLLRETTGESVQL
Mflv_4228|M.gilvum_PYR-GCK HRLLARDGDGLWRLGPALTELAGHVNDSLLAAGAVVLPRLRELTGESVQL
Mvan_2134|M.vanbaalenii_PYR-1 HRLLAREGDGQWRLGPALTELAGHVNDPLLAAGAVVLPRLRELTGESVQL
MSMEG_2386|M.smegmatis_MC2_155 HRLLARDADGRWRLGPALTELAAHVNDPLLSAGAAVLPRLREITGESVQL
TH_2042|M.thermoresistible__bu HRLLARDGDGRWCLGPAVTELAARVDDPLLAAAAVVLPRLREITGESVQL
MAB_3295|M.abscessus_ATCC_1997 HRLLSRDGDGQWQLGAGLTELAAHVNDPLLSASAQVLPKLREITGESVQL
****.* ** * **..:**** :*:*.** * : *** * : ******:
Mb3013|M.bovis_AF2122/97 YRREGTSRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHTDAATQ
Rv2989|M.tuberculosis_H37Rv YRREGTSRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHTDAATQ
MMAR_1725|M.marinum_M YRREGTSRVCVAALEPPAGLRDTVPVGARLPMTAGSGAKVLLAHSDPATQ
MUL_1967|M.ulcerans_Agy99 YRREGTSRVCVAALEPPAGLRDTVPVGARLPMTAGSGAKVLLAHSDPATQ
MAV_3839|M.avium_104 YRREGTDRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHSDAATQ
Mflv_4228|M.gilvum_PYR-GCK YRREGTSRICVAALEPPAGLRDTVPVGTRLSMTAGSGAKVLLAYADTHTQ
Mvan_2134|M.vanbaalenii_PYR-1 YRREGTTRICIAALEPPAGLRDTVPVGIRLPMTAGSGAKVLLAYADAATQ
MSMEG_2386|M.smegmatis_MC2_155 YRREGLSRVCVVALEPPAGLRDTVPVGTQLPMTAGSGAKVLLAYADAATQ
TH_2042|M.thermoresistible__bu YRREGTSRICVAALEPPAGLRDTVPVGTRLPMTAGSGAKVLLAYADSTTQ
MAB_3295|M.abscessus_ATCC_1997 YRREGTVRICVAALEPPAGLRDTVPVGSRLPMSAGSGAKVLLAHSDPGTQ
***** *:*:.****.********** :*.*:**********::*. **
Mb3013|M.bovis_AF2122/97 AAVLPKAVFSARALAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAA
Rv2989|M.tuberculosis_H37Rv AAVLPKAVFSARALAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAA
MMAR_1725|M.marinum_M QAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAA
MUL_1967|M.ulcerans_Agy99 QAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAA
MAV_3839|M.avium_104 KAVLANAKFTERTLAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAA
Mflv_4228|M.gilvum_PYR-GCK QAVLPNAKFTDRTLAEVRKRGWAQSAAEREPGVASVSAPVRDGRGAVIAA
Mvan_2134|M.vanbaalenii_PYR-1 QAVLPGAKFTDRTLAEVRRRGWAQSAAEREPGVASVSAPVRDGRGAVVAA
MSMEG_2386|M.smegmatis_MC2_155 QAVLPSAKFTERTLAEVRKRGWAQSAAEREPGVASVSAPVRDSRGQVIAA
TH_2042|M.thermoresistible__bu QAVLSNAKFSERALAEVHKRGWAQSVAEREPGVASVSAPVRDGRGTVVAA
MAB_3295|M.abscessus_ATCC_1997 AAVLPGATFTERALADVRKRGWAQSAAEREAGVASVSAPVRDRHGNVIAA
***. * *: *.**:* :******.****.*********** :* *:**
Mb3013|M.bovis_AF2122/97 ISVSGPIDRMGRRPGVRWAADLLSAADALTRRL
Rv2989|M.tuberculosis_H37Rv ISVSGPIDRMGRRPGVRWAADLLSAADALTRRL
MMAR_1725|M.marinum_M ISVSGPIDRIGRRPGARWAADLLAAADELARRL
MUL_1967|M.ulcerans_Agy99 ISVSGPIDRIGRRPGARWAADLLAAADELARRL
MAV_3839|M.avium_104 ISVSGPIDRIGRRPGARWAADLVSAAEALTRRL
Mflv_4228|M.gilvum_PYR-GCK VSVSGPIDRMGRRPGARWAADLVAAADALTRRL
Mvan_2134|M.vanbaalenii_PYR-1 VSVSGPIDRMGRRPGARWAADLVAAADALTRRL
MSMEG_2386|M.smegmatis_MC2_155 VSVSGPIDRMGRRPGARWAADLLAAAEALTRRL
TH_2042|M.thermoresistible__bu VSVSGPIDRIGRRPGARWAADLLAAAEALTRRL
MAB_3295|M.abscessus_ATCC_1997 ISVSGPIDRMGRRPGARWAADLVAASEAITARL
:********:*****.******::*:: :: **