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MTDNAIRDTPDIRPLAGVRVLELGNYIAAPTAGRMLADFGAEVIKVERPGTGDELRNWRLYAGSTSMLYR TINRNKKSIVLDLKSEAGRAVVLDLLRHCDVLLENFRPGTLEKWGLGPERLDEVNPDLVITRISAFGQTG PMSERPGFAAVAEAYGGLRELVGDPDRPPVRTGVSIGDSIAGIHAAFGTVMALFQRERAKAPTEIPLPQR IIDVALNESILSVMESLIPDYLAYGVQRQRVGGRMEGIAPSNAYPCADGTSIIVAGNGDAIYQRYMRTIG RPDLATDPDLQTNAGRWARRDELDEAISAWTIRHTRDEALKLLDEAGVPSGPIYTAADICDDQQYEARNM IQHFAVDTGGAEPQPVGFPGIVPVIGGASLPIRNVGPDLGEHTHEVLSGILGLTDAEIEALS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2023 | - | - | 100% (412) | CAIB/BAIF family protein |
| M. smegmatis MC2 155 | MSMEG_2073 | - | 3e-86 | 42.75% (400) | CAIB/BAIF family protein |
| M. smegmatis MC2 155 | MSMEG_6294 | - | 4e-67 | 37.34% (399) | caib/baif family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1897 | - | 5e-38 | 30.30% (406) | hypothetical protein Mb1897 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 5e-88 | 43.89% (401) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv1866 | - | 5e-38 | 30.30% (406) | hypothetical protein Rv1866 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 2e-87 | 43.75% (400) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 1e-85 | 43.50% (400) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_4024 | - | 2e-87 | 44.39% (401) | caib/baif family protein |
| M. thermoresistible (build 8) | TH_3905 | - | 4e-89 | 44.64% (401) | PUTATIVE Formyl-CoA transferase |
| M. ulcerans Agy99 | MUL_2446 | - | 7e-85 | 43.00% (400) | hypothetical protein MUL_2446 |
| M. vanbaalenii PYR-1 | Mvan_1895 | - | 1e-90 | 44.89% (401) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 MVTRLLADLGADVLKVQPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
Rv1866|M.tuberculosis_H37Rv MVTRLLADLGADVLKVEPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
Rv1866|M.tuberculosis_H37Rv NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
Rv1866|M.tuberculosis_H37Rv SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
Rv1866|M.tuberculosis_H37Rv AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
Rv1866|M.tuberculosis_H37Rv RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
Rv1866|M.tuberculosis_H37Rv DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MSMEG_2023|M.smegmatis_MC2_155 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
Rv1866|M.tuberculosis_H37Rv SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
MMAR_1494|M.marinum_M ----------MTEP--------GALDGIRVLELGTLIAGPFAGRLLGDMG
MUL_2446|M.ulcerans_Agy99 ----------MTEP--------GALDGIRVLELGTLIAGPFAGRLLGDMG
MAV_4024|M.avium_104 ----------MSAAGA-----AGPLDGIRVLELGTLIAGPFAGRLLGDMG
MAB_4651c|M.abscessus_ATCC_199 ----------MTGA----------LDGIRVLELGTLIAGPFAGRLLGDMG
Mflv_4465|M.gilvum_PYR-GCK ----------MTTG---------PLDGIRVIEVGTLISGPFAGRLLGDMG
Mvan_1895|M.vanbaalenii_PYR-1 ----------MTTG---------PLDGIRVIEVGTLISGPFAGRLLGDMG
TH_3905|M.thermoresistible__bu ---------VTVTG---------PLDGIRVLELGTLIAGPFAGRLLGDMG
MSMEG_2023|M.smegmatis_MC2_155 ----------MTDNAIRDTPDIRPLAGVRVLELGNYIAAPTAGRMLADFG
Mb1897|M.bovis_AF2122/97 QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
Rv1866|M.tuberculosis_H37Rv QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
: *:*::::* ::. .*::.*:*
MMAR_1494|M.marinum_M ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MUL_2446|M.ulcerans_Agy99 ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MAV_4024|M.avium_104 ADVIKVELPRAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRHPRGR
MAB_4651c|M.abscessus_ATCC_199 AEVLKIEPPGAPDPLRTWGQAEVDGHHVFWTVHARNKKAITLDLRTEAGR
Mflv_4465|M.gilvum_PYR-GCK AEVIKVEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
Mvan_1895|M.vanbaalenii_PYR-1 AEVIKIEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
TH_3905|M.thermoresistible__bu AEVIKIELPGAPDPLRTWGQAELDGHHFFWTVHARNKKAITLNLREPAGR
MSMEG_2023|M.smegmatis_MC2_155 AEVIKVERPGTGDELRNWRLYAGSTSMLYRTIN-RNKKSIVLDLKSEAGR
Mb1897|M.bovis_AF2122/97 AEVIKVESADHPDGLRQTRVGDAMSESFAWTHR--NHLALGLDLRNSEGK
Rv1866|M.tuberculosis_H37Rv AEVIKVESADHPDGLRQTRVGDAMSESFAWTHR--NHLALGLDLRNSEGK
*:*:*:* . * ** . * . *: :: *:*: *:
MMAR_1494|M.marinum_M ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MUL_2446|M.ulcerans_Agy99 ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MAV_4024|M.avium_104 ELFCELVEKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQT
MAB_4651c|M.abscessus_ATCC_199 ALFLDLVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQT
Mflv_4465|M.gilvum_PYR-GCK DLFLDLVERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQT
Mvan_1895|M.vanbaalenii_PYR-1 ELFLDLVERSDVIVENFRPGTLEKWGLGYDVLRERNRGIILVRVSGYGQT
TH_3905|M.thermoresistible__bu DVFLELVERSDIVVENFRPGTLERWDLGYDVLRSHNNRVILVRVSGYGQT
MSMEG_2023|M.smegmatis_MC2_155 AVVLDLLRHCDVLLENFRPGTLEKWGLGPERLDEVNPDLVITRISAFGQT
Mb1897|M.bovis_AF2122/97 AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
Rv1866|M.tuberculosis_H37Rv AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
:. *: ..* :. **:**** .:. : * * :::. *.:*:
MMAR_1494|M.marinum_M GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MUL_2446|M.ulcerans_Agy99 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAV_4024|M.avium_104 GPDAAKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAB_4651c|M.abscessus_ATCC_199 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------MALSIGDTLAG
Mflv_4465|M.gilvum_PYR-GCK GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
Mvan_1895|M.vanbaalenii_PYR-1 GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
TH_3905|M.thermoresistible__bu GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDTLAG
MSMEG_2023|M.smegmatis_MC2_155 GPMSERPGFAAVAEAYGGLRELVGDPDRPPVR-------TGVSIGDSIAG
Mb1897|M.bovis_AF2122/97 GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
Rv1866|M.tuberculosis_H37Rv GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
** : : *:..:..* *: .: * . : * :.*
MMAR_1494|M.marinum_M MFGAQGALAALYRR-------SVTGTGQVVDVALTESCLALQESTISDYD
MUL_2446|M.ulcerans_Agy99 MFGPQGALAALYRR-------SVTGTGQVVDVALTESCLALQESTISDYD
MAV_4024|M.avium_104 MFGAQGALAALYRR-------SVTGRGQVVDVALTESCLAVQESTIPDYD
MAB_4651c|M.abscessus_ATCC_199 MFAAQGALAALYRR-------TVTGRGQVVDAALTESCLAVQESTIPDYD
Mflv_4465|M.gilvum_PYR-GCK MFAAQGALAALYRR-------SVTGEGQIVDAALTESCLAVQESTIPDYD
Mvan_1895|M.vanbaalenii_PYR-1 MFAAQGALAALYRR-------SVTGDGQVVDAALTESCLAVQESTIPDYD
TH_3905|M.thermoresistible__bu MFAAQGAMAALYRR-------TVTGEGQVVDAALTEACLAVQESTIPDYD
MSMEG_2023|M.smegmatis_MC2_155 IHAAFGTVMALFQRERAKAPTEIPLPQRIIDVALNESILSVMESLIPDYL
Mb1897|M.bovis_AF2122/97 RVGALLALAALIHR-------DRTGGGAHVHISQAEVVVNQLDTMFVAEA
Rv1866|M.tuberculosis_H37Rv RVGALLALAALIHR-------DRTGGGAHVHISQAEVVVNQLDTMFVAEA
.. :: ** :* . :. : * : :: :
MMAR_1494|M.marinum_M VGGVVRGPSGTRLEGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCP
MUL_2446|M.ulcerans_Agy99 VGGVVRGPSGTRLKGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCP
MAV_4024|M.avium_104 VGGVVRGPSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRA
MAB_4651c|M.abscessus_ATCC_199 VGRVVRGPSGTRLEGIAPSNIYQSADGSWVVIAANQDTVFRRLCEAMGRP
Mflv_4465|M.gilvum_PYR-GCK VGGVVRGPSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQP
Mvan_1895|M.vanbaalenii_PYR-1 VGGVVRGPSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQP
TH_3905|M.thermoresistible__bu IGGVVRGPSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFRRLCAAMGRP
MSMEG_2023|M.smegmatis_MC2_155 AYGVQRQRVGGRMEGIAPSNAYPCADGTSIIVAGNGDAIYQRYMRTIGRP
Mb1897|M.bovis_AF2122/97 AR--ATDVAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQP
Rv1866|M.tuberculosis_H37Rv AR--ATDVAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQP
: . . : .* ::: . * : * .:* .
MMAR_1494|M.marinum_M ELATDDRFATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGP
MUL_2446|M.ulcerans_Agy99 ELATDDRFATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGP
MAV_4024|M.avium_104 ELATDERFATHVARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGP
MAB_4651c|M.abscessus_ATCC_199 ELSSDARFANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGP
Mflv_4465|M.gilvum_PYR-GCK ELATDERFADHVARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGP
Mvan_1895|M.vanbaalenii_PYR-1 ELATDERFANHVARGRNQDELDKIIGAWAAERQPADIIATLSEAGVISGP
TH_3905|M.thermoresistible__bu ELATDDRFATHTARGRNQDELDKIIADWAAERAPGEIIDTLNAAGVIAGP
MSMEG_2023|M.smegmatis_MC2_155 DLATDPDLQTNAGRWARRDELDEAISAWTIRHTRDEALKLLDEAGVPSGP
Mb1897|M.bovis_AF2122/97 ELANDPRFGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGP
Rv1866|M.tuberculosis_H37Rv ELANDPRFGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGP
:*:.* : .* :.:: :. *: : : *. *** :**
MMAR_1494|M.marinum_M INTVAEVVKDRQLRARGMLVEHYDERIGRN---VLGPGIVPALSESPGQV
MUL_2446|M.ulcerans_Agy99 INTVAEVVKDRQLRARGMLVEHYDERIGRN---VLGPGIVPALSESPGQV
MAV_4024|M.avium_104 INTVAEVVNDPQLRARDMLVEHYDERLRRN---VLGPGIVPVLSESPGRV
MAB_4651c|M.abscessus_ATCC_199 INTVADVVQDPQLKAREMLVEHFDERLGRS---VLGPGVVPVLSESPGGV
Mflv_4465|M.gilvum_PYR-GCK INTVAEVVEDPQLQARGMIADHWDERIGRN---VKGPGVVPVLSETPGTI
Mvan_1895|M.vanbaalenii_PYR-1 INTVAEVVKDPQLQARGMIADHWDERIGRN---VKGPGVVPVLSETPGTI
TH_3905|M.thermoresistible__bu INTVAEVVEDPQLRARGMIADHFDERIGRN---VKGPGVVPVLSESPGTI
MSMEG_2023|M.smegmatis_MC2_155 IYTAADICDDQQYEARNMIQHFAVDTGGAEPQPVGFPGIVPVIGGASLPI
Mb1897|M.bovis_AF2122/97 MNRPSDILEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAP---
Rv1866|M.tuberculosis_H37Rv MNRPSDILEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAP---
: ::: .* * * :: . *. . : :.
MMAR_1494|M.marinum_M RSAGPARPGQHNDDVYIGLLGKSIEELEQLRAEEVL-------
MUL_2446|M.ulcerans_Agy99 RSAGPARPGQHNDDVYIGLLGKSIEELEQLRAVEVL-------
MAV_4024|M.avium_104 RNAGPARPGQHNDEVYRGLLGKTAEELEELRAQEVL-------
MAB_4651c|M.abscessus_ATCC_199 RNAGPARPGQDNDDVYVGLLGKSAQDIERLRAEGVL-------
Mflv_4465|M.gilvum_PYR-GCK RSAGSARPGQHNDEIYRDLLGRSAAELDKLQEEGVL-------
Mvan_1895|M.vanbaalenii_PYR-1 RSAGSSRPGEHNDEIYRGLLGKTDAELERLRAGGVL-------
TH_3905|M.thermoresistible__bu RNAGPARPGQHNEEIYTGLLGKTAAELRQLRAQGVI-------
MSMEG_2023|M.smegmatis_MC2_155 RNVGP-DLGEHTHEVLSGILGLTDAEIEALS------------
Mb1897|M.bovis_AF2122/97 -QRPAPLPGQDSVQICRKLLGMTADETERLINERVMFGPAVTA
Rv1866|M.tuberculosis_H37Rv -QRPAPLPGQDSVQICRKLLGMTADETERLINERVMFGPAVTA
. . *:.. :: :** : : *