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TTGPLDGIRVIEVGTLISGPFAGRLLGDMGAEVIKIEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAV TLNLRVPEGRELFLDLVERSDVIVENFRPGTLEKWGLGYDVLRERNRGIILVRVSGYGQTGPDAHKAGYA SVAEAASGLRHMNGFPGGPPPRLALSLGDSLAGMFAAQGALAALYRRSVTGDGQVVDAALTESCLAVQES TIPDYDVGGVVRGPSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDERFANHVAR GRNQDELDKIIGAWAAERQPADIIATLSEAGVISGPINTVAEVVKDPQLQARGMIADHWDERIGRNVKGP GVVPVLSETPGTIRSAGSSRPGEHNDEIYRGLLGKTDAELERLRAGGVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1895 | - | - | 100% (400) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_0528 | - | 1e-70 | 37.50% (400) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_1855 | - | 9e-57 | 39.44% (322) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1897 | - | 1e-51 | 33.58% (405) | hypothetical protein Mb1897 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 0.0 | 93.75% (400) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv1866 | - | 1e-51 | 33.58% (405) | hypothetical protein Rv1866 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 0.0 | 81.91% (398) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 0.0 | 83.38% (397) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_4024 | - | 0.0 | 83.12% (397) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_2073 | - | 0.0 | 86.75% (400) | CAIB/BAIF family protein |
| M. thermoresistible (build 8) | TH_3905 | - | 0.0 | 85.93% (398) | PUTATIVE Formyl-CoA transferase |
| M. ulcerans Agy99 | MUL_2446 | - | 0.0 | 82.87% (397) | hypothetical protein MUL_2446 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 MVTRLLADLGADVLKVQPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
Rv1866|M.tuberculosis_H37Rv MVTRLLADLGADVLKVEPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
Rv1866|M.tuberculosis_H37Rv NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
Rv1866|M.tuberculosis_H37Rv SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
Rv1866|M.tuberculosis_H37Rv AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
Rv1866|M.tuberculosis_H37Rv RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
Rv1866|M.tuberculosis_H37Rv DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
Rv1866|M.tuberculosis_H37Rv SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
Mvan_1895|M.vanbaalenii_PYR-1 ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
Mflv_4465|M.gilvum_PYR-GCK ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
MSMEG_2073|M.smegmatis_MC2_155 ---------------MTAG----PLDGVRVLELGTLISGPFAGRLLGDMG
TH_3905|M.thermoresistible__bu --------------VTVTG----PLDGIRVLELGTLIAGPFAGRLLGDMG
MMAR_1494|M.marinum_M ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MUL_2446|M.ulcerans_Agy99 ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MAV_4024|M.avium_104 ---------------MSAAGAAGPLDGIRVLELGTLIAGPFAGRLLGDMG
MAB_4651c|M.abscessus_ATCC_199 ---------------MTG-----ALDGIRVLELGTLIAGPFAGRLLGDMG
Mb1897|M.bovis_AF2122/97 QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
Rv1866|M.tuberculosis_H37Rv QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
.::*:*::::* :::* .**:**:*
Mvan_1895|M.vanbaalenii_PYR-1 AEVIKIEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
Mflv_4465|M.gilvum_PYR-GCK AEVIKVEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
MSMEG_2073|M.smegmatis_MC2_155 AEVIKIELPSAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLDLRKPKGR
TH_3905|M.thermoresistible__bu AEVIKIELPGAPDPLRTWGQAELDGHHFFWTVHARNKKAITLNLREPAGR
MMAR_1494|M.marinum_M ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MUL_2446|M.ulcerans_Agy99 ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MAV_4024|M.avium_104 ADVIKVELPRAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRHPRGR
MAB_4651c|M.abscessus_ATCC_199 AEVLKIEPPGAPDPLRTWGQAEVDGHHVFWTVHARNKKAITLDLRTEAGR
Mb1897|M.bovis_AF2122/97 AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
Rv1866|M.tuberculosis_H37Rv AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
*:*:*:* . ** ** .: .. . ** **: *: *:** *:
Mvan_1895|M.vanbaalenii_PYR-1 ELFLDLVERSDVIVENFRPGTLEKWGLGYDVLRERNRGIILVRVSGYGQT
Mflv_4465|M.gilvum_PYR-GCK DLFLDLVERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQT
MSMEG_2073|M.smegmatis_MC2_155 ELFLELVDRSDIIVENFRPGTLEKWDLGYDVLRQHNKGVILVRVSGYGQT
TH_3905|M.thermoresistible__bu DVFLELVERSDIVVENFRPGTLERWDLGYDVLRSHNNRVILVRVSGYGQT
MMAR_1494|M.marinum_M ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MUL_2446|M.ulcerans_Agy99 ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MAV_4024|M.avium_104 ELFCELVEKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQT
MAB_4651c|M.abscessus_ATCC_199 ALFLDLVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQT
Mb1897|M.bovis_AF2122/97 AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
Rv1866|M.tuberculosis_H37Rv AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
:* ** .** :. **:**** .:.**** * ::*. *.:*:
Mvan_1895|M.vanbaalenii_PYR-1 GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
Mflv_4465|M.gilvum_PYR-GCK GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
MSMEG_2073|M.smegmatis_MC2_155 GPEAGKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
TH_3905|M.thermoresistible__bu GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDTLAG
MMAR_1494|M.marinum_M GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MUL_2446|M.ulcerans_Agy99 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAV_4024|M.avium_104 GPDAAKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAB_4651c|M.abscessus_ATCC_199 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------MALSIGDTLAG
Mb1897|M.bovis_AF2122/97 GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
Rv1866|M.tuberculosis_H37Rv GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
** : : **..:..**:*: :: . * . : : * :.*
Mvan_1895|M.vanbaalenii_PYR-1 MFAAQGALAALYRRSVTGDGQVVDAALTESCLAVQESTIPDYDVGGVVRG
Mflv_4465|M.gilvum_PYR-GCK MFAAQGALAALYRRSVTGEGQIVDAALTESCLAVQESTIPDYDVGGVVRG
MSMEG_2073|M.smegmatis_MC2_155 MFAAQGALAALYRRSVTGEGQVVDTALTESCLAIQESTIPDYDVGGVVRG
TH_3905|M.thermoresistible__bu MFAAQGAMAALYRRTVTGEGQVVDAALTEACLAVQESTIPDYDIGGVVRG
MMAR_1494|M.marinum_M MFGAQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MUL_2446|M.ulcerans_Agy99 MFGPQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MAV_4024|M.avium_104 MFGAQGALAALYRRSVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRG
MAB_4651c|M.abscessus_ATCC_199 MFAAQGALAALYRRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRG
Mb1897|M.bovis_AF2122/97 RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
Rv1866|M.tuberculosis_H37Rv RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
... *:*** :* ** * *. : :* : :: : . .
Mvan_1895|M.vanbaalenii_PYR-1 PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
Mflv_4465|M.gilvum_PYR-GCK PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
MSMEG_2073|M.smegmatis_MC2_155 PSGTRLEGIAPSNIYQSANGSWVVIAANQDTVFRRLCAAMGRPELATDER
TH_3905|M.thermoresistible__bu PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFRRLCAAMGRPELATDDR
MMAR_1494|M.marinum_M PSGTRLEGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MUL_2446|M.ulcerans_Agy99 PSGTRLKGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MAV_4024|M.avium_104 PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRAELATDER
MAB_4651c|M.abscessus_ATCC_199 PSGTRLEGIAPSNIYQSADGSWVVIAANQDTVFRRLCEAMGRPELSSDAR
Mb1897|M.bovis_AF2122/97 VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
Rv1866|M.tuberculosis_H37Rv VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
: : . . : :.: .* **: ..* : * .:* .**:.* *
Mvan_1895|M.vanbaalenii_PYR-1 FANHVARGRNQDELDKIIGAWAAERQPADIIATLSEAGVISGPINTVAEV
Mflv_4465|M.gilvum_PYR-GCK FADHVARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEV
MSMEG_2073|M.smegmatis_MC2_155 FSDHLARGRNQDELDKIIGDWAAQRQPDEIISTLSDAGVIAGPINTVAEV
TH_3905|M.thermoresistible__bu FATHTARGRNQDELDKIIADWAAERAPGEIIDTLNAAGVIAGPINTVAEV
MMAR_1494|M.marinum_M FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MUL_2446|M.ulcerans_Agy99 FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MAV_4024|M.avium_104 FATHVARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MAB_4651c|M.abscessus_ATCC_199 FANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADV
Mb1897|M.bovis_AF2122/97 FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
Rv1866|M.tuberculosis_H37Rv FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
*. :* :.:: :. *:: * * : .*. *** :**:* :::
Mvan_1895|M.vanbaalenii_PYR-1 VKDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSSRPGE
Mflv_4465|M.gilvum_PYR-GCK VEDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSARPGQ
MSMEG_2073|M.smegmatis_MC2_155 VNDPQLQARGMIADHWDERVQRNIKGPGVVPVLSESPGTIRNAGSARPGQ
TH_3905|M.thermoresistible__bu VEDPQLRARGMIADHFDERIGRNVKGPGVVPVLSESPGTIRNAGPARPGQ
MMAR_1494|M.marinum_M VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MUL_2446|M.ulcerans_Agy99 VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MAV_4024|M.avium_104 VNDPQLRARDMLVEHYDERLRRNVLGPGIVPVLSESPGRVRNAGPARPGQ
MAB_4651c|M.abscessus_ATCC_199 VQDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQ
Mb1897|M.bovis_AF2122/97 LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
Rv1866|M.tuberculosis_H37Rv LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
::* ** * :: : . : * : . . : . * : ... **:
Mvan_1895|M.vanbaalenii_PYR-1 HNDEIYRGLLGKTDAELERLRAGGVL-------
Mflv_4465|M.gilvum_PYR-GCK HNDEIYRDLLGRSAAELDKLQEEGVL-------
MSMEG_2073|M.smegmatis_MC2_155 HNDEIYTGLLGHTADELQTLHDEGVL-------
TH_3905|M.thermoresistible__bu HNEEIYTGLLGKTAAELRQLRAQGVI-------
MMAR_1494|M.marinum_M HNDDVYIGLLGKSIEELEQLRAEEVL-------
MUL_2446|M.ulcerans_Agy99 HNDDVYIGLLGKSIEELEQLRAVEVL-------
MAV_4024|M.avium_104 HNDEVYRGLLGKTAEELEELRAQEVL-------
MAB_4651c|M.abscessus_ATCC_199 DNDDVYVGLLGKSAQDIERLRAEGVL-------
Mb1897|M.bovis_AF2122/97 DSVQICRKLLGMTADETERLINERVMFGPAVTA
Rv1866|M.tuberculosis_H37Rv DSVQICRKLLGMTADETERLINERVMFGPAVTA
.. :: *** : : * *: