For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ALHRLDSIVLGVPDLAAAATFYEDFGLIPHDGHRFASTEGGVQLELVHSARRRLVSARFAVDDDDDLQRA ARELRRSEFAAVLPEPGRLHTVEPTTGAEIELITAPRLDQAPYAAPPVNAPGRNDRVDARAAGIMITDRV RPRRLGHIVIGSPDYETAYAFFVSGLGFKVSDLVKGHGAFLRCSTDHHNVLLQRAPVPFLHHSSWQVDDV DAIGRGAMALLEDHPERHVWGLGRHYAGSNFFWYFKDPANNFAEYHSDMDCIVDDALWTPEELEGARGLY QWGPPPPASFLHPEDLAEHMIHGHSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2006 | - | - | 100% (307) | 2,3-dihydroxybiphenyl 1,2-dioxygenase |
| M. smegmatis MC2 155 | MSMEG_2891 | - | 5e-05 | 24.66% (219) | biphenyl-2,3-diol 1,2-dioxygenase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0675 | - | 6e-08 | 33.59% (128) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2576c | - | 9e-19 | 30.10% (309) | putative 2,3-dihydroxybiphenyl-1,2-dioxygenase or |
| M. marinum M | MMAR_2985 | bphC_1 | 1e-22 | 31.63% (313) | 2,3-dihydroxybiphenyl-1,2-dioxygenase BphC_1 |
| M. avium 104 | MAV_1802 | - | 1e-24 | 29.90% (301) | 2,3-dihydroxybiphenyl-1,2-dioxygenase |
| M. thermoresistible (build 8) | TH_4499 | - | 9e-05 | 23.31% (236) | PUTATIVE biphenyl-2,3-diol 1,2-dioxygenase 1 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4908 | - | 1e-21 | 30.07% (306) | glyoxalase/bleomycin resistance protein/dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2985|M.marinum_M MTKEVAVDAMVDIGGDLNKGVHQDMHSEQGARPDEHPGRSGNPIIKVVDL
Mvan_4908|M.vanbaalenii_PYR-1 ---------MVKLRNDG----HKHLHSEQGARRGEHPGRSTNPLIRVADI
MAB_2576c|M.abscessus_ATCC_199 --------------MNDLIGAHNELHSEQGGLKGEHCGRARNPVIKVTDI
MAV_1802|M.avium_104 ---------MEELQMTSTVGAHNGLHSERGARKGEHPGRSRNPVIKVDDL
Mflv_0675|M.gilvum_PYR-GCK --------------------------------------------MLVKTL
TH_4499|M.thermoresistible__bu ------------------------------------MRHERDTMGFIKSL
MSMEG_2006|M.smegmatis_MC2_155 --------------------------------------------MALHRL
: :
MMAR_2985|M.marinum_M AWLEFEKPDLVRTEAFA-RAFGLQTAWRSPDELRLRGTDAGAACAIVRRA
Mvan_4908|M.vanbaalenii_PYR-1 AWLEFDKPDLVRAEAFA-RAFGLGVASSDPRQLVLRGTDAGCPCLIVRPG
MAB_2576c|M.abscessus_ATCC_199 AWLEFEKPDLQRAEAFA-RAFGFATSLRTGEELHLRGSDSTAPCVIVRRG
MAV_1802|M.avium_104 AWLEFQKPDLVRAEAFA-HAFGFTTVLRSDDELQLRGTDAGTPCVLIRRG
Mflv_0675|M.gilvum_PYR-GCK GYVGVESPDAKEWLAFGPEVLG-MEAVEAASGSVLLRIDDADHRLAVHHG
TH_4499|M.thermoresistible__bu GYVIVQATDMDRWRHFAYEVLGFAEGTGPNPEALYLRMDERTARITVEPG
MSMEG_2006|M.smegmatis_MC2_155 DSIVLGVPDLAAAATFY-EDFG----LIPHDGHRFASTEGGVQLELVHSA
: . .* * . :* : :. .
MMAR_2985|M.marinum_M PRTRFAGVAYRACDEVDVLRLADKCGATARPLPETIGGLTVDLVDPSGMA
Mvan_4908|M.vanbaalenii_PYR-1 THSRFTGVAFRAADEVDVLRLADKVHAPVQPLPEALGGVAVQLTDPSGIA
MAB_2576c|M.abscessus_ATCC_199 NRSRFLGVAFAAVDGADLLRLATATGARTRPLPAAIGGMAVDLVDPGGVP
MAV_1802|M.avium_104 PRSRFAGVAFQAADEADLRRLGKATGAPIQALPATIGGTTVDLVDPSGIP
Mflv_0675|M.gilvum_PYR-GCK DRNRMLYAGWDVGSEEALEAAGELLHK---------RGIGFEVGTEEDCA
TH_4499|M.thermoresistible__bu EVDRIVTIGWEVRDHAALEDVKRALAA---------AGVPHRQLSTAEAD
MSMEG_2006|M.smegmatis_MC2_155 RR-RLVSARFAVDDDDDLQRAARELRRSEFAAVLPEPGRLHTVEPTTGAE
*: : . . : *
MMAR_2985|M.marinum_M VRVVAGMDELPALPTQQPSVLNFGHDLSRAN-LPQRPPRVPARIQRLGHV
Mvan_4908|M.vanbaalenii_PYR-1 VKVVGGLHELPELPTQSPLLLNTGRKTLRTN-ATQRPLRAPARVQRLGHV
MAB_2576c|M.abscessus_ATCC_199 VHVVAGMHSLGALPTQALHRYNMGHDFRRIN-ATQRPRREPTTVQRLGHL
MAV_1802|M.avium_104 VRVVAGAHQLEALPAQTPHTFNFGHELRRAN-ATQRPPREPARVQRLGHV
Mflv_0675|M.gilvum_PYR-GCK ARGVLGFVTLSDPSGLRHELFYGQKVVPGSFRPGRAISGFVTGAQGLGHV
TH_4499|M.thermoresistible__bu ARRVEEVVAFADPAGTALEVFHGP-VLDHSPVVTPFGARFVTGDQGLGHV
MSMEG_2006|M.smegmatis_MC2_155 IELIT-APRLDQAPYAAPPVNAPGRNDRVDARAAGIMITDRVRPRRLGHI
. : : . . : ***:
MMAR_2985|M.marinum_M VVQSTRYAEALNWYLDHLGMIVSDFQFFPGQRDRGPT-MSFIRCDRGSTP
Mvan_4908|M.vanbaalenii_PYR-1 VLQSTTYLATLNWYLDTLGMIVSDFLYFPGQRDRGPT-MSFIRCDRGDSP
MAB_2576c|M.abscessus_ATCC_199 VMQSTKYLETLNWYLDTLGMIVSDFLYFPGQRDRGPT-MSFIRCDRGSTP
MAV_1802|M.avium_104 VMQTTTYLQALDWYLDHLGLIVSDFLFFPGQRDRGPT-MSFIRCDRGQTP
Mflv_0675|M.gilvum_PYR-GCK VLATPDLAQADRFLRGVLGFKK-------SDEIYTFMDLWFYHCN-----
TH_4499|M.thermoresistible__bu VLPTVDVDGLFEFYTEVLGFRSRGAFRVPAPEEFGPVRVRFLGIN-----
MSMEG_2006|M.smegmatis_MC2_155 VIGSPDYETAYAFFVSGLGFKVS-------DLVKGHG--AFLRCS-----
*: : : **: * .
MMAR_2985|M.marinum_M ADHHTLAMALGPANR---YLHSAYQVSDLDALAAGGEYLKERG-YFRSWG
Mvan_4908|M.vanbaalenii_PYR-1 ADHHTLALALGPANR---YVHSAYQVSDLDALAAGGEYLRDRG-YFRSWG
MAB_2576c|M.abscessus_ATCC_199 ADHHTLALALGPQNR---YVHSAYQVCDLDALAAGGEYLTEQG-YFRSWG
MAV_1802|M.avium_104 ADHHTLAMALGPSNR---YVHSAYQVCDLDALAAGGEYLKDHG-YQRSWG
Mflv_0675|M.gilvum_PYR-GCK PRHHSIALTPMPGVR--GLHHVMVEVQSFDDVGMAYDLCMSRN-IPLSMT
TH_4499|M.thermoresistible__bu ERHHSLALCPASTLRDPGLIHLMVEVDTLDAVGQALDRVNRDG-YQLSST
MSMEG_2006|M.smegmatis_MC2_155 TDHHNVLLQRAPVPF---LHHSSWQVDDVDAIGRGAMALLEDHPERHVWG
**.: : . * :* .* :. .
MMAR_2985|M.marinum_M IGRHIQGSQIFDYWRDPDGFLVEHFTDGDMFDNSLEPGWAPLTAS---GL
Mvan_4908|M.vanbaalenii_PYR-1 IGRHIQGSQLFDYWRDPDGFLVEHFTDGDMFDNTVEPGWAPFTAT---GL
MAB_2576c|M.abscessus_ATCC_199 IGRHIQGSQLFDYWRDPDGFMVEHFTDGDLFDSTLQPGWAPFTAS---GL
MAV_1802|M.avium_104 IGRHIQGSQIFDYWRDPDGFLVEHFSDGDMFDCTLEPGWAPFTAS---GL
Mflv_0675|M.gilvum_PYR-GCK LGRHVNDRMVSFYARTPSGFDIEYGWDAVTVD---DDTWTVAQYD---RP
TH_4499|M.thermoresistible__bu LGRHTNDKMVSFYVRAPGDWDIEFGTAGMRVD---ETYYTAEEIT---AD
MSMEG_2006|M.smegmatis_MC2_155 LGRHYAGSNFFWYFKDPANNFAEYHSDMDCIVD--DALWTPEELEGARGL
:*** . . * : * . *. . : ::
MMAR_2985|M.marinum_M AQWGPPATKDFLGTGPKSARHELVSMITALRATNEFDFNRLIGLLKVPSL
Mvan_4908|M.vanbaalenii_PYR-1 AQWGPPVSRDFLGTTPKHAPQELRSMVSALRDRNEFDLTRLIGLLKVASS
MAB_2576c|M.abscessus_ATCC_199 AQWGPPVSKDFLGTNPKSLPHEAQSIFAALRGDNEFDINRLIGLLKVANS
MAV_1802|M.avium_104 AQWGPPASKNFLGTNPKALPHEACSMISALRHRNEFDIHRLIGLMKVANS
Mflv_0675|M.gilvum_PYR-GCK SVWG----HQMVAQTPPGALEAATT-------------------------
TH_4499|M.thermoresistible__bu SYWG----HQWVGDLP-AAMRP----------------------------
MSMEG_2006|M.smegmatis_MC2_155 YQWGPPPPASFL--HPEDLAEHMIHGHSG---------------------
** . : * .