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STRELVVLGTASQVPTRLRNHNGYLLRWDNEGFLFDPGEGTQRQMLLAGVSASSVTHLCLTHFHGDHCLG VPGIVQRMSLDHVAHPVEAHYPASGQEFFTRLRNASAFHDTVDVRENPVEADGPVAIGAFGTLEARRLDH SVDSIGYRLTEPDSRRIRSDLLALYGIHGPAVGELQREGTIRVGPDTEPEVVHLTQVSEPRPGQRFAFVM DTRLCDAVYALADGTDMLVIESTFLNEHAGLALKYGHLTARQAARVAAECHVRKLVLTHFSQRYGDTQRH FEEAAEVYHGELVVADDLARIAVGHRSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1776 | - | - | 100% (309) | ribonuclease Z |
| M. smegmatis MC2 155 | MSMEG_4568 | - | 6e-10 | 27.16% (313) | ribonuclease Z |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2430 | - | 2e-11 | 26.84% (313) | ribonuclease Z |
| M. gilvum PYR-GCK | Mflv_2669 | - | 9e-10 | 25.48% (310) | ribonuclease Z |
| M. tuberculosis H37Rv | Rv2407 | - | 6e-11 | 26.92% (312) | ribonuclease Z |
| M. leprae Br4923 | MLBr_01173 | - | 1e-10 | 26.09% (276) | hypothetical protein MLBr_01173 |
| M. abscessus ATCC 19977 | MAB_1483 | - | 3e-06 | 25.91% (274) | hypothetical protein MAB_1483 |
| M. marinum M | MMAR_4043 | - | 4e-09 | 24.60% (313) | metal-dependent hydrolase |
| M. avium 104 | MAV_1774 | - | 3e-10 | 26.77% (310) | ribonuclease Z |
| M. thermoresistible (build 8) | TH_1057 | - | 1e-125 | 71.01% (307) | ribonuclease Z |
| M. ulcerans Agy99 | MUL_3909 | - | 2e-09 | 25.16% (318) | metal-dependent hydrolase |
| M. vanbaalenii PYR-1 | Mvan_5799 | - | 1e-120 | 67.75% (307) | ribonuclease Z |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1057|M.thermoresistible__bu MVSVRELIVLGTASQVPTRYRNHNGYFLRWDQEG-FLFDPGEGTQRQMLL
Mvan_5799|M.vanbaalenii_PYR-1 -MSGRELIVFGTASQVPTRHRNHNGYLLRWDDEG-FLFDPGEGTQRQMLL
MSMEG_1776|M.smegmatis_MC2_155 -MSTRELVVLGTASQVPTRLRNHNGYLLRWDNEG-FLFDPGEGTQRQMLL
Mb2430|M.bovis_AF2122/97 ---MLEITLLGTGSPIPDPDRAGPSTLVRAGAQA-FLVDCGRGVLQRAAA
Rv2407|M.tuberculosis_H37Rv ---MLEITLLGTGSPIPDPDRAGPSTLVRAGAQA-FLVDCGRGVLQRAAA
MAV_1774|M.avium_104 ---MIEVTLLGTGSPIPDPNRAGPSTLVRAGGQV-FLVDCGRGVLQRAAA
Mflv_2669|M.gilvum_PYR-GCK ---MIEVTLLGTGSPIPDARRAGPSTLVRAGGQT-FLVDCGRGVLQRAAA
MMAR_4043|M.marinum_M ----MRITVLGCSGSVVGPDSAASGYLLRAPDTPPIVIDFGGGVLG--AL
MUL_3909|M.ulcerans_Agy99 --MSVRITVLGCSGSVVGPDSAASGYLLRAPDTPPIVIDFGGGVVG--AL
MLBr_01173|M.leprae_Br4923 --MTVRITVLGCSGSVVGPDSPASGYLLRAPDTPPLVLDFGGGVLG--AL
MAB_1483|M.abscessus_ATCC_1997 ----MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLVIDFGGGVLG--SL
.: ::* .. : . :: ::.* * *.
TH_1057|M.thermoresistible__bu AGVSAAGLTRLCLTHFHGDHCLGVPGVIQRLSLDRVAHPVTAHYPRSGRE
Mvan_5799|M.vanbaalenii_PYR-1 AGVSPTAVTRMCITHLHGDHCLGVPGIIQRLSLDRVVRPVQAYYPASGRE
MSMEG_1776|M.smegmatis_MC2_155 AGVSASSVTHLCLTHFHGDHCLGVPGIVQRMSLDHVAHPVEAHYPASGQE
Mb2430|M.bovis_AF2122/97 VGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAA------------
Rv2407|M.tuberculosis_H37Rv VGVGAAGLSAVLLTHLH-------GDVLITSWVTNFAA------------
MAV_1774|M.avium_104 VGVGAAGLSTLLLTHLHSDHVGDLGDVLITRWVSTFTP------------
Mflv_2669|M.gilvum_PYR-GCK VGVGANQISALLLTHLHSDHIADLGDVLITRWVSNFAP------------
MMAR_4043|M.marinum_M QRHLDPASVHVLLSHLHADHCLDMPGLFVWRRYHPSRP------------
MUL_3909|M.ulcerans_Agy99 QRHLDPASVHVLLSHLHADHCLDMPGLFVWRRYHPSRP------------
MLBr_01173|M.leprae_Br4923 QRHADPGSVHVLLSHLHADHCLDMPGLFVWRRYHPTRP------------
MAB_1483|M.abscessus_ATCC_1997 QRFADPGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPP------------
: ::*:* .:.
TH_1057|M.thermoresistible__bu YFARLRHACAFHEVADLREEPVDSDGPVATGRFGTLEARRLDHSIESIGY
Mvan_5799|M.vanbaalenii_PYR-1 YFARLRHASVFHDVTDVREMPVDAEGAIADGPFGTLEARRLDHPVDAVGY
MSMEG_1776|M.smegmatis_MC2_155 FFTRLRNASAFHDTVDVRENPVEADGPVAIGAFGTLEARRLDHSVDSIGY
Mb2430|M.bovis_AF2122/97 ---------------DPAPLPIIGPPGTAEVVEATLKAFGHD-----IGY
Rv2407|M.tuberculosis_H37Rv ---------------DPAPLPIIGPPGTAEVVEATLKAFGHD-----IGY
MAV_1774|M.avium_104 ---------------DPVPLPIIGPPGTAELVAATLNALRHD-----IGY
Mflv_2669|M.gilvum_PYR-GCK ---------------DLPPLPIIGPPGTAEVVENMLKAFSFD-----IGY
MMAR_4043|M.marinum_M -----------------KGKALLYGPSDTWSRLGAASSPFGG--------
MUL_3909|M.ulcerans_Agy99 -----------------KGKALLYGPSDTWSRLGAASSPFGG--------
MLBr_01173|M.leprae_Br4923 -----------------VGKALLYGPDDTWLRLGAASSPYGG--------
MAB_1483|M.abscessus_ATCC_1997 -----------------KGKAIMYGPADTLVRVGAASAEIGG--------
.: : .: .
TH_1057|M.thermoresistible__bu RLTEPDGRRFDARKLAEFGVHGPAVRRLQADGELVVD----GRLVRLSDV
Mvan_5799|M.vanbaalenii_PYR-1 RVVEPDGDRFVPELLAQFGVAGPEVGQLQRAGLLRRG----TQTVRLSDV
MSMEG_1776|M.smegmatis_MC2_155 RLTEPDSRRIRSDLLALYGIHGPAVGELQREGTIRVGPDTEPEVVHLTQV
Mb2430|M.bovis_AF2122/97 RIAHHADLTTPPPIEVHEYTAGPAWDRDGVT--IRVAPTDHRPVTPTIGF
Rv2407|M.tuberculosis_H37Rv RIAHHADLTTPPPIEVHEYTAGPAWDRDGVT--IRVAPTDHRPVTPTIGF
MAV_1774|M.avium_104 RIAHHADLNAPPAVDVREHTDGPVWDRDGVS--IRVAPTDHRPVAPTIGF
Mflv_2669|M.gilvum_PYR-GCK RIAHHDDLTTPPPVEVEEVTDGVVWGRDEVS--IRVGPTDHRPVTPTIGF
MMAR_4043|M.marinum_M -----EIDDCSDIFDVRHWVDGEPVTLGGVT----VVPTVVAHPTESYGM
MUL_3909|M.ulcerans_Agy99 -----EIDDCSDIFDVRHWVDGEPVTLGGVT----VVPTVVAHPTESYGM
MLBr_01173|M.leprae_Br4923 -----EIDDCSDIFDVRHWVDGEPVPLGALM----IMPRLVAHPTESYGL
MAB_1483|M.abscessus_ATCC_1997 -----EVDDFTDIFDVFPWADGEPVQFGSLT----VTPTRVAHPPESYGL
. * .
TH_1057|M.thermoresistible__bu SE-PRPGQRFAFVMDTRLCDAVFDLADRADLLVIEATFLSADADLAREYG
Mvan_5799|M.vanbaalenii_PYR-1 TR-SRRGQRFAFVMDTRLCDGVYALADGADLLVIEATFLDSDADLAARYG
MSMEG_1776|M.smegmatis_MC2_155 SE-PRPGQRFAFVMDTRLCDAVYALADGTDMLVIESTFLNEHAGLALKYG
Mb2430|M.bovis_AF2122/97 RI-ESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRV
Rv2407|M.tuberculosis_H37Rv RI-ESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRV
MAV_1774|M.avium_104 RV-DYQGASVVLAGDTVPCAGLDELAAGAGALVHTVIRKDIVATIPQQRL
Mflv_2669|M.gilvum_PYR-GCK RI-EHHGASVVLAGDTVPCRGLDKLAAGAGALVHTVIRRDLIEALPMQRI
MMAR_4043|M.marinum_M RFTDSTGASLAYSGDTGMCDQLIELARGVDVFLCEASWTHSP-DRPPDLH
MUL_3909|M.ulcerans_Agy99 RFTDSTGASLAYSGDTGMCDQLIELARGVDVFLCEASWTHSP-DRPPDLH
MLBr_01173|M.leprae_Br4923 RITDPSGASLVYSGDTGSCDQLVELARGADVFLCEASWTHSP-DRPPNLH
MAB_1483|M.abscessus_ATCC_1997 RIEDSSGTVLAYSGDTGICDAVVDLARGADVFLCEASWTHMPGHRPPDLH
* .. ** * : ** .. :: .
TH_1057|M.thermoresistible__bu ------HLTARQAAQVADRCGVRRLVLTHFSQRYR--DLSAFRDEAAEVF
Mvan_5799|M.vanbaalenii_PYR-1 ------HLTARQAAQVATECGVRRLVLTHFSQRYP--DMRGHHDEARAVF
MSMEG_1776|M.smegmatis_MC2_155 ------HLTARQAARVAAECHVRKLVLTHFSQRYG--DTQRHFEEAAEVY
Mb2430|M.bovis_AF2122/97 KDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEF
Rv2407|M.tuberculosis_H37Rv KDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEF
MAV_1774|M.avium_104 QDICDYHSSVEQAAATAARAGVGTLVMTHYVPALVAGQEEQWRALAAREF
Mflv_2669|M.gilvum_PYR-GCK RDICDYHSSVEQAAETATRAGVGILILTHYVPTLQPGQEDDWRALAATRF
MMAR_4043|M.marinum_M -------LSGTEAGRAAARAGVRELLLTHIPPWTS---REDVISEAKAEF
MUL_3909|M.ulcerans_Agy99 -------LSGTEAGRAAARAGVRELLLTHIPPWTS---REDVISEAKAEF
MLBr_01173|M.leprae_Br4923 -------LSGTEAGRAAAQASVRELLLTHIPPWTS---REDVISEAKAEF
MAB_1483|M.abscessus_ATCC_1997 -------LSGTEAGQIATRAGVKELLLTHIPPWTS---REDVIAEAKSAF
: :*. * .. * *::** * :
TH_1057|M.thermoresistible__bu DGDLVVAEDLARIPVPRRR------
Mvan_5799|M.vanbaalenii_PYR-1 DGDLVLAEDLARVKMPPRR------
MSMEG_1776|M.smegmatis_MC2_155 HGELVVADDLARIAVGHRSS-----
Mb2430|M.bovis_AF2122/97 SGRIEVGNDLHRVEVHPRR------
Rv2407|M.tuberculosis_H37Rv SGRIEVGNDLHRVEVHPRR------
MAV_1774|M.avium_104 AGRVELGDDLHRVQVDAPS------
Mflv_2669|M.gilvum_PYR-GCK DRQIEIGDDLHRVQVHPGVCAKPAG
MMAR_4043|M.marinum_M DGPVHAVVCDETFEVSLG-------
MUL_3909|M.ulcerans_Agy99 DGPVHAVVCDETFEVSLG-------
MLBr_01173|M.leprae_Br4923 DGPVHAVVSGETFDIQAPERV----
MAB_1483|M.abscessus_ATCC_1997 DGPVHAVVAGENIDL----------
: . :