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MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTHLHGDVLITS WVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIR VAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDY HSSVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2407 | - | - | 100% (273) | ribonuclease Z |
| M. tuberculosis H37Rv | Rv3796 | - | 1e-19 | 26.21% (309) | hypothetical protein Rv3796 |
| M. tuberculosis H37Rv | Rv1339 | - | 2e-09 | 29.55% (247) | hypothetical protein Rv1339 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2430 | - | 1e-156 | 97.50% (280) | ribonuclease Z |
| M. gilvum PYR-GCK | Mflv_2669 | - | 1e-119 | 74.46% (278) | ribonuclease Z |
| M. leprae Br4923 | MLBr_01173 | - | 5e-09 | 27.02% (248) | hypothetical protein MLBr_01173 |
| M. abscessus ATCC 19977 | MAB_1483 | - | 2e-11 | 28.81% (243) | hypothetical protein MAB_1483 |
| M. marinum M | MMAR_3727 | - | 1e-137 | 86.02% (279) | metal-dependent hydrolase |
| M. avium 104 | MAV_1774 | - | 1e-125 | 78.26% (276) | ribonuclease Z |
| M. smegmatis MC2 155 | MSMEG_4568 | - | 1e-123 | 75.90% (278) | ribonuclease Z |
| M. thermoresistible (build 8) | TH_1457 | - | 1e-116 | 70.14% (278) | CONSERVED HYPOTHETCAL PROTEIN |
| M. ulcerans Agy99 | MUL_3670 | - | 1e-137 | 86.02% (279) | ribonuclease Z |
| M. vanbaalenii PYR-1 | Mvan_3908 | - | 1e-121 | 75.54% (278) | ribonuclease Z |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2407|M.tuberculosis_H37Rv --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD
Mb2430|M.bovis_AF2122/97 --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD
MMAR_3727|M.marinum_M --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD
MUL_3670|M.ulcerans_Agy99 --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD
MAV_1774|M.avium_104 --------------MIEVTLLGTGSPIPDPNRAGPSTLVRAG-GQVFLVD
Mflv_2669|M.gilvum_PYR-GCK --------------MIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD
Mvan_3908|M.vanbaalenii_PYR-1 MSPVGRPPRVTSGLMIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD
MSMEG_4568|M.smegmatis_MC2_155 --------------MIEVTLLGTGSPIPDPDRAGPSTMVRAG-GQTFLVD
TH_1457|M.thermoresistible__bu --------------MIEVTLLGTGSPVPDAHRAGPSTLVRAG-HQTLLID
MLBr_01173|M.leprae_Br4923 -------------MTVRITVLGCSGSVVGPDSPASGYLLRAPDTPPLVLD
MAB_1483|M.abscessus_ATCC_1997 ---------------MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLVID
:.:*:** ...: .. .... :: * :::*
Rv2407|M.tuberculosis_H37Rv CGRGVLQRAAAVGVGAAGLSAVLLTHLH-------GDVLITSWVTNFAAD
Mb2430|M.bovis_AF2122/97 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
MMAR_3727|M.marinum_M CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
MUL_3670|M.ulcerans_Agy99 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
MAV_1774|M.avium_104 CGRGVLQRAAAVGVGAAGLSTLLLTHLHSDHVGDLGDVLITRWVSTFTPD
Mflv_2669|M.gilvum_PYR-GCK CGRGVLQRAAAVGVGANQISALLLTHLHSDHIADLGDVLITRWVSNFAPD
Mvan_3908|M.vanbaalenii_PYR-1 CGRGVLQRLAAVGVGANNITALLLTHLHSDHIADLGDVLITRWVSNFAPD
MSMEG_4568|M.smegmatis_MC2_155 CGRGVLQRLAAAGSSASQLSALLLTHLHSDHIADLGDVIITRWVSTFTPD
TH_1457|M.thermoresistible__bu CGRGVQQRMAGAETSATALTALLLTHLHSDHIADLGDLLITRWISNFDPQ
MLBr_01173|M.leprae_Br4923 FGGGVLG--ALQRHADPGSVHVLLSHLHADHCLDMPGLFVWRRYHPTRPV
MAB_1483|M.abscessus_ATCC_1997 FGGGVLG--SLQRFADPGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPPK
* ** : . :**:*** .::: .
Rv2407|M.tuberculosis_H37Rv PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA
Mb2430|M.bovis_AF2122/97 PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA
MMAR_3727|M.marinum_M PAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD
MUL_3670|M.ulcerans_Agy99 PAPLQVIGPPGTAETVEAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD
MAV_1774|M.avium_104 PVPLPIIGPPGTAELVAATLNALRHDIGYRIAHHADLNAPPAVDVREHTD
Mflv_2669|M.gilvum_PYR-GCK LPPLPIIGPPGTAEVVENMLKAFSFDIGYRIAHHDDLTTPPPVEVEEVTD
Mvan_3908|M.vanbaalenii_PYR-1 LAPLPIIGPPGTAEVVENTLKAFGFDIGYRIAHHADLTTPPPVEVEEVTE
MSMEG_4568|M.smegmatis_MC2_155 APPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHDDLTAPPPVEVHEHTE
TH_1457|M.thermoresistible__bu LPPLPIIGPPGTAEVVSATLRAFGHDIGYRMKHHADLTTPPQVDVKEATE
MLBr_01173|M.leprae_Br4923 GKAL-LYGPDDTWLRLGAASSPYGGEID---------DCSDIFDVRHWVD
MAB_1483|M.abscessus_ATCC_1997 GKAI-MYGPADTLVRVGAASAEIGGEVD---------DFTDIFDVFPWAD
.: : ** .* : ::. . .:* .
Rv2407|M.tuberculosis_H37Rv GPAWDRDGVTIRVAPTDHRPVTPTIGFRIES-DGASVVLAGDTVPCDSLD
Mb2430|M.bovis_AF2122/97 GPAWDRDGVTIRVAPTDHRPVTPTIGFRIES-DGASVVLAGDTVPCDSLD
MMAR_3727|M.marinum_M GTVWDRDGVAIRVAPTDHRPVAPTIGFRVEF-DGASAVLAGDTVPCPSLD
MUL_3670|M.ulcerans_Agy99 GTVWDRDGVAIRVAPTDHRPVAPTIGFRVEF-DGASAVLAGGTVPCPSLD
MAV_1774|M.avium_104 GPVWDRDGVSIRVAPTDHRPVAPTIGFRVDY-QGASVVLAGDTVPCAGLD
Mflv_2669|M.gilvum_PYR-GCK GVVWGRDEVSIRVGPTDHRPVTPTIGFRIEH-HGASVVLAGDTVPCRGLD
Mvan_3908|M.vanbaalenii_PYR-1 GVVWGRDEVSIRVGPTDHRPVTPTIGFRIEH-NGASVVLAGDTVPCRGLD
MSMEG_4568|M.smegmatis_MC2_155 GVVWDRDGVVIRVGPTDHRPVTPTIAFRVEH-ADASVVAAGDSVPCATLD
TH_1457|M.thermoresistible__bu GVVWDVDGVRIRVAPTDHRPVTPTIGFRVEH-DGASVVLAGDTVPCESLD
MLBr_01173|M.leprae_Br4923 GEPVPLG--ALMIMPRLVAHPTESYGLRITDPSGASLVYSGDTGSCDQLV
MAB_1483|M.abscessus_ATCC_1997 GEPVQFG--SLTVTPTRVAHPPESYGLRIEDSSGTVLAYSGDTGICDAVV
* . : : * . : .:*: .: . :*.: * :
Rv2407|M.tuberculosis_H37Rv QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG
Mb2430|M.bovis_AF2122/97 QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG
MMAR_3727|M.marinum_M ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG
MUL_3670|M.ulcerans_Agy99 ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG
MAV_1774|M.avium_104 ELAAGAGALVHTVIRKDIVATIPQQRLQDICDYHSSVEQAAATAARAGVG
Mflv_2669|M.gilvum_PYR-GCK KLAAGAGALVHTVIRRDLIEALPMQRIRDICDYHSSVEQAAETATRAGVG
Mvan_3908|M.vanbaalenii_PYR-1 ELAAGAGALVHTVIRPDLIEAMPVQRIRDICDYHSSVEQAADTATRAGVG
MSMEG_4568|M.smegmatis_MC2_155 ALATGAGALIHTVIRKDIIETLPQQRIRDICDYHSSVQEAAATAARAGVG
TH_1457|M.thermoresistible__bu ELAAGAGAMVHTVIRKELIAQLPQQRIREICEYHSSPQEAGATAERAGVG
MLBr_01173|M.leprae_Br4923 ELARGADVFLCEASWTHSP-DRPPN-------LHLSGTEAGRAAAQASVR
MAB_1483|M.abscessus_ATCC_1997 DLARGADVFLCEASWTHMPGHRPPD-------LHLSGTEAGQIATRAGVK
** **..:: . . * : * * :*. * :*.*
Rv2407|M.tuberculosis_H37Rv TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR----
Mb2430|M.bovis_AF2122/97 TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR----
MMAR_3727|M.marinum_M TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR-----
MUL_3670|M.ulcerans_Agy99 TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR-----
MAV_1774|M.avium_104 TLVMTHYVPALVAGQEEQWRALAAREFAGRVELGDDLHRVQVDAPS----
Mflv_2669|M.gilvum_PYR-GCK ILILTHYVPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHPGVCAKP
Mvan_3908|M.vanbaalenii_PYR-1 ILILTHYVPTLQPGQEEDWRALAASVFDRQIEIGDDLHRVEVHPGVGARP
MSMEG_4568|M.smegmatis_MC2_155 ILILTHYVPAIAPGTEDQWRELAATEFDRQIEVGADLHRVEVHPGVCVKP
TH_1457|M.thermoresistible__bu ILILTHYLPPVQPGQEDEWRAQAATTFSRQIEVGDDLHRVQVHPGVGSAR
MLBr_01173|M.leprae_Br4923 ELLLTHIPPWTS---REDVISEAKAEFDGPVHAVVSGETFDIQAPERV--
MAB_1483|M.abscessus_ATCC_1997 ELLLTHIPPWTS---REDVIAEAKSAFDGPVHAVVAGENIDL--------
*::** * .:: * * :. . .::
Rv2407|M.tuberculosis_H37Rv -----
Mb2430|M.bovis_AF2122/97 -----
MMAR_3727|M.marinum_M -----
MUL_3670|M.ulcerans_Agy99 -----
MAV_1774|M.avium_104 -----
Mflv_2669|M.gilvum_PYR-GCK AG---
Mvan_3908|M.vanbaalenii_PYR-1 AG---
MSMEG_4568|M.smegmatis_MC2_155 AG---
TH_1457|M.thermoresistible__bu FGTSP
MLBr_01173|M.leprae_Br4923 -----
MAB_1483|M.abscessus_ATCC_1997 -----