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IEVTLLGTGSPIPDARRAGPSTLVRAGGQTFLVDCGRGVLQRAAAVGVGANQISALLLTHLHSDHIADLG DVLITRWVSNFAPDLPPLPIIGPPGTAEVVENMLKAFSFDIGYRIAHHDDLTTPPPVEVEEVTDGVVWGR DEVSIRVGPTDHRPVTPTIGFRIEHHGASVVLAGDTVPCRGLDKLAAGAGALVHTVIRRDLIEALPMQRI RDICDYHSSVEQAAETATRAGVGILILTHYVPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHPGVC AKPAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2669 | - | - | 100% (286) | ribonuclease Z |
| M. gilvum PYR-GCK | Mflv_2357 | - | 5e-06 | 27.45% (255) | beta-lactamase-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2430 | - | 1e-125 | 76.62% (278) | ribonuclease Z |
| M. tuberculosis H37Rv | Rv2407 | - | 1e-119 | 74.46% (278) | ribonuclease Z |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1483 | - | 7e-11 | 31.05% (277) | hypothetical protein MAB_1483 |
| M. marinum M | MMAR_3727 | - | 1e-123 | 75.81% (277) | metal-dependent hydrolase |
| M. avium 104 | MAV_1774 | - | 1e-122 | 76.45% (276) | ribonuclease Z |
| M. smegmatis MC2 155 | MSMEG_4568 | - | 1e-136 | 81.12% (286) | ribonuclease Z |
| M. thermoresistible (build 8) | TH_1457 | - | 1e-126 | 76.43% (280) | CONSERVED HYPOTHETCAL PROTEIN |
| M. ulcerans Agy99 | MUL_3670 | - | 1e-122 | 75.81% (277) | ribonuclease Z |
| M. vanbaalenii PYR-1 | Mvan_3908 | - | 1e-155 | 93.01% (286) | ribonuclease Z |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2430|M.bovis_AF2122/97 --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD
Rv2407|M.tuberculosis_H37Rv --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD
MMAR_3727|M.marinum_M --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD
MUL_3670|M.ulcerans_Agy99 --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD
MAV_1774|M.avium_104 --------------MIEVTLLGTGSPIPDPNRAGPSTLVRAG-GQVFLVD
Mflv_2669|M.gilvum_PYR-GCK --------------MIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD
Mvan_3908|M.vanbaalenii_PYR-1 MSPVGRPPRVTSGLMIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD
MSMEG_4568|M.smegmatis_MC2_155 --------------MIEVTLLGTGSPIPDPDRAGPSTMVRAG-GQTFLVD
TH_1457|M.thermoresistible__bu --------------MIEVTLLGTGSPVPDAHRAGPSTLVRAG-HQTLLID
MAB_1483|M.abscessus_ATCC_1997 ---------------MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLVID
:.:*:** ...:... .... :: * :::*
Mb2430|M.bovis_AF2122/97 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
Rv2407|M.tuberculosis_H37Rv CGRGVLQRAAAVGVGAAGLSAVLLTHLH-------GDVLITSWVTNFAAD
MMAR_3727|M.marinum_M CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
MUL_3670|M.ulcerans_Agy99 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD
MAV_1774|M.avium_104 CGRGVLQRAAAVGVGAAGLSTLLLTHLHSDHVGDLGDVLITRWVSTFTPD
Mflv_2669|M.gilvum_PYR-GCK CGRGVLQRAAAVGVGANQISALLLTHLHSDHIADLGDVLITRWVSNFAPD
Mvan_3908|M.vanbaalenii_PYR-1 CGRGVLQRLAAVGVGANNITALLLTHLHSDHIADLGDVLITRWVSNFAPD
MSMEG_4568|M.smegmatis_MC2_155 CGRGVLQRLAAAGSSASQLSALLLTHLHSDHIADLGDVIITRWVSTFTPD
TH_1457|M.thermoresistible__bu CGRGVQQRMAGAETSATALTALLLTHLHSDHIADLGDLLITRWISNFDPQ
MAB_1483|M.abscessus_ATCC_1997 FGGGVLG--SLQRFADPGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPPK
* ** : . ::**:*** .::: ..
Mb2430|M.bovis_AF2122/97 PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA
Rv2407|M.tuberculosis_H37Rv PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA
MMAR_3727|M.marinum_M PAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD
MUL_3670|M.ulcerans_Agy99 PAPLQVIGPPGTAETVEAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD
MAV_1774|M.avium_104 PVPLPIIGPPGTAELVAATLNALRHDIGYRIAHHADLNAPPAVDVREHTD
Mflv_2669|M.gilvum_PYR-GCK LPPLPIIGPPGTAEVVENMLKAFSFDIGYRIAHHDDLTTPPPVEVEEVTD
Mvan_3908|M.vanbaalenii_PYR-1 LAPLPIIGPPGTAEVVENTLKAFGFDIGYRIAHHADLTTPPPVEVEEVTE
MSMEG_4568|M.smegmatis_MC2_155 APPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHDDLTAPPPVEVHEHTE
TH_1457|M.thermoresistible__bu LPPLPIIGPPGTAEVVSATLRAFGHDIGYRMKHHADLTTPPQVDVKEATE
MAB_1483|M.abscessus_ATCC_1997 GK-AIMYGPADTLVRVG----AASAEIGGEVDDFTDI-----FDVFPWAD
: **..* * * :** .: .. *: .:* :
Mb2430|M.bovis_AF2122/97 GPAWDRDGVTIRVAPTDHRPVTPTIGFRIE-SDGASVVLAGDTVPCDSLD
Rv2407|M.tuberculosis_H37Rv GPAWDRDGVTIRVAPTDHRPVTPTIGFRIE-SDGASVVLAGDTVPCDSLD
MMAR_3727|M.marinum_M GTVWDRDGVAIRVAPTDHRPVAPTIGFRVE-FDGASAVLAGDTVPCPSLD
MUL_3670|M.ulcerans_Agy99 GTVWDRDGVAIRVAPTDHRPVAPTIGFRVE-FDGASAVLAGGTVPCPSLD
MAV_1774|M.avium_104 GPVWDRDGVSIRVAPTDHRPVAPTIGFRVD-YQGASVVLAGDTVPCAGLD
Mflv_2669|M.gilvum_PYR-GCK GVVWGRDEVSIRVGPTDHRPVTPTIGFRIE-HHGASVVLAGDTVPCRGLD
Mvan_3908|M.vanbaalenii_PYR-1 GVVWGRDEVSIRVGPTDHRPVTPTIGFRIE-HNGASVVLAGDTVPCRGLD
MSMEG_4568|M.smegmatis_MC2_155 GVVWDRDGVVIRVGPTDHRPVTPTIAFRVE-HADASVVAAGDSVPCATLD
TH_1457|M.thermoresistible__bu GVVWDVDGVRIRVAPTDHRPVTPTIGFRVE-HDGASVVLAGDTVPCESLD
MAB_1483|M.abscessus_ATCC_1997 GEPVQFGSLTVTPTRVAHPPES--YGLRIEDSSGTVLAYSGDTGICDAVV
* . : : . * * : .:*:: .: . :*.: * :
Mb2430|M.bovis_AF2122/97 QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG
Rv2407|M.tuberculosis_H37Rv QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG
MMAR_3727|M.marinum_M ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG
MUL_3670|M.ulcerans_Agy99 ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG
MAV_1774|M.avium_104 ELAAGAGALVHTVIRKDIVATIPQQRLQDICDYHSSVEQAAATAARAGVG
Mflv_2669|M.gilvum_PYR-GCK KLAAGAGALVHTVIRRDLIEALPMQRIRDICDYHSSVEQAAETATRAGVG
Mvan_3908|M.vanbaalenii_PYR-1 ELAAGAGALVHTVIRPDLIEAMPVQRIRDICDYHSSVEQAADTATRAGVG
MSMEG_4568|M.smegmatis_MC2_155 ALATGAGALIHTVIRKDIIETLPQQRIRDICDYHSSVQEAAATAARAGVG
TH_1457|M.thermoresistible__bu ELAAGAGAMVHTVIRKELIAQLPQQRIREICEYHSSPQEAGATAERAGVG
MAB_1483|M.abscessus_ATCC_1997 DLARGADVFLCEASWTHMPGHRPP-------DLHLSGTEAGQIATRAGVK
** **..:: . .: * : * * :*. * ****
Mb2430|M.bovis_AF2122/97 TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR----
Rv2407|M.tuberculosis_H37Rv TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR----
MMAR_3727|M.marinum_M TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR-----
MUL_3670|M.ulcerans_Agy99 TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR-----
MAV_1774|M.avium_104 TLVMTHYVPALVAGQEEQWRALAAREFAGRVELGDDLHRVQVDAPS----
Mflv_2669|M.gilvum_PYR-GCK ILILTHYVPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHPGVCAKP
Mvan_3908|M.vanbaalenii_PYR-1 ILILTHYVPTLQPGQEEDWRALAASVFDRQIEIGDDLHRVEVHPGVGARP
MSMEG_4568|M.smegmatis_MC2_155 ILILTHYVPAIAPGTEDQWRELAATEFDRQIEVGADLHRVEVHPGVCVKP
TH_1457|M.thermoresistible__bu ILILTHYLPPVQPGQEDEWRAQAATTFSRQIEVGDDLHRVQVHPGVGSAR
MAB_1483|M.abscessus_ATCC_1997 ELLLTHIPPWTS---REDVIAEAKSAFDGPVHAVVAGENIDL--------
*::** * .:: * * :. ..:::
Mb2430|M.bovis_AF2122/97 -----
Rv2407|M.tuberculosis_H37Rv -----
MMAR_3727|M.marinum_M -----
MUL_3670|M.ulcerans_Agy99 -----
MAV_1774|M.avium_104 -----
Mflv_2669|M.gilvum_PYR-GCK AG---
Mvan_3908|M.vanbaalenii_PYR-1 AG---
MSMEG_4568|M.smegmatis_MC2_155 AG---
TH_1457|M.thermoresistible__bu FGTSP
MAB_1483|M.abscessus_ATCC_1997 -----