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MSDGGHQLRGAQALATLVDLGFPAIASGVIARRPPVLGLLERMQADERAGRRMHRLRSEFGRGPVELVIP GRRIVVVTDPEDVAAVLVQAPEPFHPANREKRKALQWFQPHGVLISQGPIREQRRTVNEAALDSGAAMHR LAESFAAKVAAEADTLVARTLPGQRLDADEFMTAWWRLVRRLTLGERARDDHAITDQLARLRRAGNWSFL SLPHYRARSRFLSHLYRYAEDPEPGTLVGALADVPAGGAVDPVGQIPQWLFAFDAAGMALLRALAVLATH PLQRDRALEDAGEPNRPLLRPYLRGCLLESVRLWPTTPAILRDTTEDTHWREGAERFTVAKGAGLLIVAP AFHRDDQVLPFAHDFVPEIWIDGRAQLYPQLVPFSAGPAECPGRNLVLFTTSTLAANLLNRLHFDVRSEP RPVPGEPLPMTFNHAGIEFSLRPARRAVTAATVDPAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1775 | - | - | 100% (457) | cytochrome P450 monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4801 | - | 6e-09 | 32.52% (163) | cytochrome P450 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2151c | - | 1e-05 | 24.07% (162) | putative cytochrome P450 |
| M. marinum M | MMAR_0852 | cyp185A4 | 6e-05 | 25.95% (262) | cytochrome P450 185A4 Cyp185A4 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0136 | - | 5e-07 | 25.71% (175) | PROBABLE CYTOCHROME P450 137 CYP137 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4801|M.gilvum_PYR-GCK -------MVDHRQPFPPLPHPPRRVPVVGDVFGFSADILTR---PPSDPG
MAB_2151c|M.abscessus_ATCC_199 MRSIDTDSVAPAVPKPPVPRLPPRLPIHKAALLGLSCLGDP---TRLPYL
TH_0136|M.thermoresistible__bu ------------VRPPSLPAPAPLSAVFGAGYAAAYAVGGNRMVARMLKR
MMAR_0852|M.marinum_M --------MVDSPDVRSLPLAPRNPLPYWQQLKALKTLHVG---SEALRD
MSMEG_1775|M.smegmatis_MC2_155 --------MSDGGHQLRGAQALATLVDLGFPAIASGVIARR---PPVLGL
. : .
Mflv_4801|M.gilvum_PYR-GCK LGPVFEFRFLGAR--YVVAASADAVAEVND----ERRFCKHVG---PDID
MAB_2151c|M.abscessus_ATCC_199 LLPKIANRYGDIVRLFTGPTPALTLTLINHPDYVDHVFTRHHDRYVKHEA
TH_0136|M.thermoresistible__bu YGPVVALPVLGYGTVVAVADPALARQVFAEK---PDVLLGGDG-----VG
MMAR_0852|M.marinum_M AGGSVTRIWLGPKRLVPPMVMVTSPQGARDVLGRSGALSDRGT----LPL
MSMEG_1775|M.smegmatis_MC2_155 LERMQADERAGRRMHRLRSEFGRGPVELVIPGRRIVVVTDPED-----VA
. .
Mflv_4801|M.gilvum_PYR-GCK ALRIMGGDGLFTAYNEEPNWQRAHDLLMPAFSQQAMRGYHSAMLDAADGL
MAB_2151c|M.abscessus_ATCC_199 TIELVSGEPVALPLLEGREWKRVRSAFNPYFGERALAQATPLMMEGITER
TH_0136|M.thermoresistible__bu PAAAIYG-PRSMFVQEEPEHLRRRRLLIPPLHGAALAGHVPVIEAATRSA
MMAR_0852|M.marinum_M LKDLRRAIGESVLNLPHDTWLPRRRTLQPIFTKQRVAGFAGHMSEAANHI
MSMEG_1775|M.smegmatis_MC2_155 AVLVQAPEPFHPANREKRKALQWFQPHGVLISQGPIREQRRTVNEAALDS
: : : .
Mflv_4801|M.gilvum_PYR-GCK VARWDGKARTGASVDVPADATRVTLETIGQCAAGHPFGCFDTEDPHPFVE
MAB_2151c|M.abscessus_ATCC_199 VDAWSRHVHSGELVDLEHELGAVVMDGLMR-------SMFKVRLRPAEID
TH_0136|M.thermoresistible__bu MASWP----VGRPMRMLDAARDLTLDVIIR-------VIFGVHDP-AEVA
MMAR_0852|M.marinum_M LLGWP----DGAEVDLNAASHALVLRVVGH-------SVFGLDLQ--DKA
MSMEG_1775|M.smegmatis_MC2_155 GAAMHR-LAESFAAKVAAEADTLVARTLPG-------------QRLDADE
. : :. :
Mflv_4801|M.gilvum_PYR-GCK HMVAGLK--GSDWVGVLR--ETVLPNFFARRAER-RVRRHAVQMHRIADE
MAB_2151c|M.abscessus_ATCC_199 HAVDGARRYGVYVISRVA--MHFLPRWLPNPLRR-SGEEAKAELFGILDR
TH_0136|M.thermoresistible__bu RLAAPFETLLALAVSVQTPVRYALRRAGALRFWH-AYRDANRRIDELVRP
MMAR_0852|M.marinum_M DVITTGVTLAAKWAADRSARPVRAPHWLPTPARR-RARGAYDAMYKIAAD
MSMEG_1775|M.smegmatis_MC2_155 FMTAWWRLVRRLTLGERARDDHAITDQLARLRRAGNWSFLSLPHYRARSR
. .
Mflv_4801|M.gilvum_PYR-GCK IVSERLRDGLGHHDDLLELMLTSDLD------PANIRYQLINFLVAGHET
MAB_2151c|M.abscessus_ATCC_199 FVQERAGCPSTGTPDLVDTLLALEFDGCPQIRERRRRSEAAGLVFAGFET
TH_0136|M.thermoresistible__bu LIAARRVPDAGPRDDILSMLVAARTEDGDRLTDDEIRDDLITLVLAGHET
MMAR_0852|M.marinum_M MLAACRADPNREAPLIRALIDATDPNTGESLSDQQICDEMVYFMILGEDT
MSMEG_1775|M.smegmatis_MC2_155 FLSHLYRYAEDPEPGTLVGALADVPAGG-----AVDPVGQIPQWLFAFDA
:: : . . ::
Mflv_4801|M.gilvum_PYR-GCK TSGALSFALYFLSRHPEVADRARAEVAEVWGDDERPGFELIAKLRYVRRV
MAB_2151c|M.abscessus_ATCC_199 TAAALAWTIALLCRNPIALGKAYAEVDALGG--KTLAYDDLENLKYLRAC
TH_0136|M.thermoresistible__bu TATTLAWLIDYLVHHPAALDRVRAEAAPGGA--------QRGAGPYTEAV
MMAR_0852|M.marinum_M TSTVLTYALWALGRHSQLQDRVAAEAAELGD--RPLTPADVPRLGYTIQV
MSMEG_1775|M.smegmatis_MC2_155 AGMALLRALAVLATHPLQRDRALEDAGEPNR---------PLLRPYLRGC
:. .* : * :. .:. :. *
Mflv_4801|M.gilvum_PYR-GCK LDEALRLQPTVPGYYREAREDTVLAG---VHPMRQGDWVLAMTMALHRDP
MAB_2151c|M.abscessus_ATCC_199 FDEAQRFQ-AAPANVRTAIEDDEVGG---YFIPR-GSQVIITQYALQRDP
TH_0136|M.thermoresistible__bu INETLRLRPPGPVTGRTTAGHYRLGD---YTLAP-RTRIVLLLGVINRDP
MMAR_0852|M.marinum_M LQEAMRLCPPGPTVARRAMQDIEVDG---YRVQA-GTYCLVGVYAMHRDP
MSMEG_1775|M.smegmatis_MC2_155 LLESVRLWPTTPAILRDTTEDTHWREGAERFTVAKGAGLLIVAPAFHRDD
: *: *: . * * : . : .::**
Mflv_4801|M.gilvum_PYR-GCK RWGGDPDAFDPDRFAPDRVRARPAGLYKPFGTGPRSCIGRQFALHEAVLL
MAB_2151c|M.abscessus_ATCC_199 RFWNEPERFNPDRFLTDRINRN---TFLPFSIGPRKCMGTRMAYIEGTLV
TH_0136|M.thermoresistible__bu NSYPDPHDFRPDRFLHTRPDPY---AWVPFGGGVKRCLGAAFAMRELTTI
MMAR_0852|M.marinum_M ALWDDPLAFDPDRFAPKKSKGRDRWQYLPFGGGGRSCLGDHFAMLEASLA
MSMEG_1775|M.smegmatis_MC2_155 QVLPFAHDFVPEIWIDGRAQLYP--QLVPFSAGPAECPGRNLVLFTTSTL
. * *: : : **. * * * :.
Mflv_4801|M.gilvum_PYR-GCK LAVLLRRYDLVPEPGYQLQVAQRLTL-MPKDFRLTLRRRRSE--------
MAB_2151c|M.abscessus_ATCC_199 LGAILQRYAFQIRDGWTPRHRVRVSTGLAGGLPARLFAR-----------
TH_0136|M.thermoresistible__bu LRILLTEADLRPVNARPESAAGRAAAVVVPRHGTPVYFRPTAPAASPRCA
MMAR_0852|M.marinum_M LATIIREAEIHSLDG-DFPVAIPLPIVPAGPIRARVNQRRPSQEVCTTTL
MSMEG_1775|M.smegmatis_MC2_155 AANLLNRLHFDVRSEPRPVPGEPLPMTFNHAG-IEFSLRPARRAVTAATV
:: . : . . *
Mflv_4801|M.gilvum_PYR-GCK ----------
MAB_2151c|M.abscessus_ATCC_199 ----------
TH_0136|M.thermoresistible__bu GRTSTV----
MMAR_0852|M.marinum_M SDSSASSSAS
MSMEG_1775|M.smegmatis_MC2_155 DPAT------