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SEQPRGASRRAEYAELTRRAIIDAARELFAQRGYVRTKVDDIATRARVSPATVYAVAGGKQGLLHTLVDE WTQAPEVAEAYAAINTAETADAVMELTSSAVRRMRGDWGDVMRIVLTTAPQDDTAAERLQVATERYRAAM HIVATRLCELNALKPGITVKDAVDVLWFFFGYTGFFTLLDDNGWSPDKAERWLRDTASASLLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1745 | - | - | 100% (204) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3976 | - | 1e-19 | 28.44% (211) | DNA-binding protein |
| M. smegmatis MC2 155 | MSMEG_5282 | - | 3e-09 | 32.00% (125) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 4e-08 | 50.00% (52) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1947 | - | 1e-07 | 46.15% (52) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 4e-08 | 50.00% (52) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1149 | - | 1e-09 | 53.85% (52) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1268 | - | 8e-09 | 31.07% (206) | putative regulatory protein |
| M. avium 104 | MAV_1159 | - | 1e-08 | 46.88% (64) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2719 | - | 4e-09 | 43.08% (65) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4635 | - | 4e-08 | 50.00% (52) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0929 | - | 2e-09 | 34.76% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1047|M.bovis_AF2122/97 ----------------------MTGTERRHQLIGIARSLFAERGYDGTSI
Rv1019|M.tuberculosis_H37Rv ----------------------MTGTERRHQLIGIARSLFAERGYDGTSI
MUL_4635|M.ulcerans_Agy99 ----------------------MTGSERRHQLIGIARSLFAERGYDGTSI
MAV_1159|M.avium_104 MAVLDSQTHKDPDKEVRAPRARMTGSERRQQLIGIARSLFAERGYEGTSI
Mflv_1947|M.gilvum_PYR-GCK ----------------------MTGSERRQQLIEIAKSLFAERGFDGTSI
MAB_1149|M.abscessus_ATCC_1997 -----MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARSLFAERGYEATSI
TH_2719|M.thermoresistible__bu ----------------MASRRAQISEESRRLLIAAATELFAEQGFRRTTF
MSMEG_1745|M.smegmatis_MC2_155 ----------MSEQPRGASRRAEYAELTRRAIIDAARELFAQRGYVRTKV
MMAR_1268|M.marinum_M -MLTSMERKRQRNTTRVREAGAASRAQTRHLLLTAAAEEFARVGYVASTV
Mvan_0929|M.vanbaalenii_PYR-1 ------------MTTADGVRRRGRSVQKRLAILDAARELFIRDGYELTSV
* :: * . * . *: :..
Mb1047|M.bovis_AF2122/97 EEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMS--ALLDG--ITSSLTN
Rv1019|M.tuberculosis_H37Rv EEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMS--ALLDG--ITSSLTN
MUL_4635|M.ulcerans_Agy99 EEIAQRANVSKPVVYEHFGGKEGLYAVVVDREMS--ALLDG--ITSSLTN
MAV_1159|M.avium_104 EEIALRANVSKPVVYEHFGGKEGLYAVVVDREMS--ALLDG--ITSSLTN
Mflv_1947|M.gilvum_PYR-GCK EEIALRANVSKPVVYEHFGGKEGLYAVVVDREMS--ALLDG--ITSSLAD
MAB_1149|M.abscessus_ATCC_1997 EEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMS--VLLDG--ITSSLTS
TH_2719|M.thermoresistible__bu ADIAERSGISRGSIPWHFGNKDGLLRAVIEDFIAGVIELDA--SEQTLSE
MSMEG_1745|M.smegmatis_MC2_155 DDIATRARVSPATVYAVAGGKQGLLHTLVDEWTQAPEVAEA--YAAINTA
MMAR_1268|M.marinum_M SRIAEGAGVTVQTLYLAWGSKRALLRGYLESTLAPDAAPSGQHFAAQLQP
Mvan_0929|M.vanbaalenii_PYR-1 DAIAARAEVSKRTVYDHFGDKERIHTAVLERVNERLTATIQAALDEELTA
** : :: : *.* : ::
Mb1047|M.bovis_AF2122/97 NRSRVRVERVALALLTYVEERTDGFRIMIRDSPASISSGTYSSLLNDAVS
Rv1019|M.tuberculosis_H37Rv NRSRVRVERVALALLTYVEERTDGFRIMIRDSPASISSGTYSSLLNDAVS
MUL_4635|M.ulcerans_Agy99 NRSRVRVERVALALLTYVEERTDGFRIMIRDSPASISSGTYSSLLNDAVS
MAV_1159|M.avium_104 NRSRVRVERVALALLTYVEERTDGFRIMIRDSPAAISSGTYSSLLNDAVS
Mflv_1947|M.gilvum_PYR-GCK NRSRVRVERVALALLTYVEERTDGFRILIRDSPASITQGTYSTLLNDAVS
MAB_1149|M.abscessus_ATCC_1997 YRSRVRLEQVALALLSYIEERTDGFRILIRDSPPGVSSGTYSSLLNDAVS
TH_2719|M.thermoresistible__bu GLDRIR---------DYVRRPTTRLLITLVAEAVEPDS-PVHAFYAQLHD
MSMEG_1745|M.smegmatis_MC2_155 ETADAVMELTSSAVRRMRGDWGDVMRIVLTTAPQDDTAAERLQVATERYR
MMAR_1268|M.marinum_M DSPAGTLAQVSALVCDAARRSAIAWRAYRDGSGVDSAIAAEWHQVQMLRR
Mvan_0929|M.vanbaalenii_PYR-1 GCDLRAGLLAFVRRVATEAFPSSDYADYRHLTTRCAPGRRNPRSIANAPR
Mb1047|M.bovis_AF2122/97 QVSSILAGDFARR-GLDPDLAP-LYAQALVGSVSMTAQWWLDAREPKKEV
Rv1019|M.tuberculosis_H37Rv QVSSILAGDFARR-GLDPDLAP-LYAQALVGSVSMTAQWWLDAREPKKEV
MUL_4635|M.ulcerans_Agy99 QVSSILAGDFARR-GLDSELAP-LYAQALVGSVSMTAQWWLDAREPKKEV
MAV_1159|M.avium_104 QVSSILAGDFARR-GLDPDLAP-LYAQALVGSVSMTAQWWLDTREPKKEV
Mflv_1947|M.gilvum_PYR-GCK QVESILAGDFSRR-GLDPDLAP-LYAQALVGSVSMAAQWWLDVREPKKEV
MAB_1149|M.abscessus_ATCC_1997 QVSSILAGDFQRR-GLDAEMAP-LYAQALVGQVSMTAQWWLDAREPKKEV
TH_2719|M.thermoresistible__bu TLRKWLSDWIDDK-DIPPGVSRENFVTVLIGAVIGVHQQWRVAPHHVD--
MSMEG_1745|M.smegmatis_MC2_155 AAMHIVATRLCELNALKPGITVKDAVDVLWFFFGYTGFFTLLDDNGWS--
MMAR_1268|M.marinum_M ETMRALLVTIPDD---ALRLPRQDAVDTAWAITSPASHEIMVTHGGFT--
Mvan_0929|M.vanbaalenii_PYR-1 ELFVRRMEAFADEGAIRTERPRRAAQHFVALTFQLALDTLDPTETGAWDA
: . .
Mb1047|M.bovis_AF2122/97 VAAHLVNLVWNGLTHLEADPRLQDE----
Rv1019|M.tuberculosis_H37Rv VAAHLVNLVWNGLTHLEADPRLQDE----
MUL_4635|M.ulcerans_Agy99 VAAHLVNLVWNGLTHLEADPQLQDE----
MAV_1159|M.avium_104 VAAHLVNLMWNGLTHLEADPRLQDE----
Mflv_1947|M.gilvum_PYR-GCK VAAHLVNLCWNGLTHLESDPVLHEE----
MAB_1149|M.abscessus_ATCC_1997 VAAHIVNLCWHGLKHLEADPQLHEE----
TH_2719|M.thermoresistible__bu -----LDACFAALKQLASGD---------
MSMEG_1745|M.smegmatis_MC2_155 -----PDKAERWLRDTASASLLR------
MMAR_1268|M.marinum_M -----LQRFEAWLTTTLQNAILRDPEGSG
Mvan_0929|M.vanbaalenii_PYR-1 VDEILVDGVDVFIRSYT------------
: :