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TTADGVRRRGRSVQKRLAILDAARELFIRDGYELTSVDAIAARAEVSKRTVYDHFGDKERIHTAVLERVN ERLTATIQAALDEELTAGCDLRAGLLAFVRRVATEAFPSSDYADYRHLTTRCAPGRRNPRSIANAPRELF VRRMEAFADEGAIRTERPRRAAQHFVALTFQLALDTLDPTETGAWDAVDEILVDGVDVFIRSYT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0929 | - | - | 100% (205) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0257 | - | 5e-11 | 37.00% (100) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4778 | - | 2e-09 | 37.33% (75) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 2e-10 | 34.00% (100) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0414 | - | 1e-10 | 37.00% (100) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 2e-10 | 34.00% (100) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 1e-11 | 37.00% (100) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 9e-11 | 42.67% (75) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0500 | - | 2e-10 | 34.00% (100) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4919 | - | 7e-11 | 36.00% (100) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0363 | - | 8e-12 | 39.18% (97) | TetR-family protein regulatory protein |
| M. thermoresistible (build 8) | TH_0452 | - | 2e-10 | 37.37% (99) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1163 | - | 1e-10 | 34.00% (100) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 ------------------------MAGGTKR---LPRAVREQQMLDAAVQ
Rv0238|M.tuberculosis_H37Rv ------------------------MAGGTKR---LPRAVREQQMLDAAVQ
MMAR_0500|M.marinum_M ------------------------MAGGTKR---LPRAIREQQMLDAAVQ
MUL_1163|M.ulcerans_Agy99 ------------------------MAGGTKR---LPRAIREQQMLDAAVQ
MAV_4919|M.avium_104 ------------------------MAGGTKR---LPRAVREQQMLDAAVQ
MLBr_02568|M.leprae_Br4923 ------------------------MAGGAKR---IPRAVREQQMLDAAVQ
Mflv_0414|M.gilvum_PYR-GCK ------------------------MAGGTKR---LPRAVREQQMLDAAVE
MSMEG_0363|M.smegmatis_MC2_155 ----------------------MGMAGGTKR---LPRAVREQQMLDAAVQ
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MAB_1149|M.abscessus_ATCC_1997 ----------------MAVPSRPDVPGRTPR-VRMAGSERRRQLIDVARS
Mvan_0929|M.vanbaalenii_PYR-1 ----------------------MTTADGVRR--RGRSVQKRLAILDAARE
.. * :. :: .* .
Mb0244|M.bovis_AF2122/97 MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
Rv0238|M.tuberculosis_H37Rv MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
MMAR_0500|M.marinum_M MFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFID
MUL_1163|M.ulcerans_Agy99 MFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFID
MAV_4919|M.avium_104 MFSVNGYHETSMDAIAAQAQISKPMLYLYYGSKEDLFGACLNRELGRFID
MLBr_02568|M.leprae_Br4923 MFSVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIA
Mflv_0414|M.gilvum_PYR-GCK IFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELFGACLHRELTRFVD
MSMEG_0363|M.smegmatis_MC2_155 MFSVNGYHETSMDAIAAAAEISKPMLYLYYGSKEELFGACLDRELRRFVD
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MAB_1149|M.abscessus_ATCC_1997 LFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLD
Mvan_0929|M.vanbaalenii_PYR-1 LFIRDGYELTSVDAIAARAEVSKRTVYDHFGDKERIHTAVLERVNERLTA
:* **. :.:: ** * :** :* ::..* :. . :.* :
Mb0244|M.bovis_AF2122/97 ALRSSINFDQSPKDLLRNTIVSFLR------YIDANRASWIVMYT-QATS
Rv0238|M.tuberculosis_H37Rv ALRSSINFDQSPKDLLRNTIVSFLR------YIDANRASWIVMYT-QATS
MMAR_0500|M.marinum_M AVRADIDLSQSPKDLLRNAIVSFLR------YIDQNQASWIVMYT-QAVS
MUL_1163|M.ulcerans_Agy99 AVRADIDLSQSPKDLLRNAIVSFLR------YIDQNQASWIVMYT-QAVS
MAV_4919|M.avium_104 AVRADIDFQQSPNDMLRNTIASFMR------YIDANRASWIVMYT-QATS
MLBr_02568|M.leprae_Br4923 MVRADIDFTQSPKDLLRNTIVSFLR------YIDANRASWIVMYI-QAMS
Mflv_0414|M.gilvum_PYR-GCK EVNSNIDFTAPPKELLRTAVLAFLN------YIDANRASWMVLYT-QATS
MSMEG_0363|M.smegmatis_MC2_155 TVRGQIDFSQSPKELLRTAVLAFLT------YIDRNRASWMVLYT-QATS
TH_0452|M.thermoresistible__bu GVRQALRTTTDNRQRLRAAVQAFFD------FIEHDGQGYRLIFENDYVT
MAB_1149|M.abscessus_ATCC_1997 GITSSLTSYRS-RVRLEQVALALLS------YIEERTDGFRILIR--DSP
Mvan_0929|M.vanbaalenii_PYR-1 TIQAALDEELTAGCDLRAGLLAFVRRVATEAFPSSDYADYRHLTTRCAPG
: : *. ::. : . .: :
Mb0244|M.bovis_AF2122/97 SQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVG--AGE
Rv0238|M.tuberculosis_H37Rv SQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVG--AGE
MMAR_0500|M.marinum_M SQAFAQTVREGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVG--AGE
MUL_1163|M.ulcerans_Agy99 SQAFAQTVREGREQIVELVAGMLRAGTRSPRSDAEIDMMAAALVG--AGE
MAV_4919|M.avium_104 SQAFAHMVREGREQIIELVAGLMRAGSRTPRTDREHEMMAVALVG--AGE
MLBr_02568|M.leprae_Br4923 LPAFAQTVREARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVG--AGE
Mflv_0414|M.gilvum_PYR-GCK SQAFAHTVREGRERIIEIVGRLLRSGTRFPEPDTDFDMMAVALVG--AGE
MSMEG_0363|M.smegmatis_MC2_155 SQAFAHTVREGRERIIDLVARLLSTGTRNPQPDSDFEMMAVALVG--AGE
TH_0452|M.thermoresistible__bu EPQVAAQVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAIS--VDC
MAB_1149|M.abscessus_ATCC_1997 PGVSSGTYSSLLNDAVSQVSSILAGDFQRRGLDAEMAPLYAQALVGQVSM
Mvan_0929|M.vanbaalenii_PYR-1 RRNPRSIANAPRELFVRRMEAFADEGAIRTERPRRAAQHFVALTFQLALD
: : : . .
Mb0244|M.bovis_AF2122/97 AVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDR-LETGH---------
Rv0238|M.tuberculosis_H37Rv AVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDR-LETGH---------
MMAR_0500|M.marinum_M AVANRLSAGDTDVDEAAEMMIDLFWRGLKGAPSDREIGSNFAAG------
MUL_1163|M.ulcerans_Agy99 AVANRLSAGDTDVDEAAEMMIDLLWRGLKGAPSDREIGSNFAAG------
MAV_4919|M.avium_104 AVANRLSTGDIDVDEAAALMIDLFWYGLKGSPEEREAAAAQPEADRSGAG
MLBr_02568|M.leprae_Br4923 AMATRLTTGDIAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG------
Mflv_0414|M.gilvum_PYR-GCK AIASRVSTGDADVHEASELMINLFWRGLKGSPSAASDRDADATDATAVIT
MSMEG_0363|M.smegmatis_MC2_155 AIATRVSTGDADVDEAAELMINLFWRGLKGTPSDAGTPPVSAGSSG----
TH_0452|M.thermoresistible__bu ARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS--------------
MAB_1149|M.abscessus_ATCC_1997 TAQWWLDAREPKKEVVAAHIVNLCWHGLKHLEADPQLHEE----------
Mvan_0929|M.vanbaalenii_PYR-1 TLDPTETGAWDAVDEILVDGVDVFIRSYT---------------------
: . ::. . .
Mb0244|M.bovis_AF2122/97 -
Rv0238|M.tuberculosis_H37Rv -
MMAR_0500|M.marinum_M -
MUL_1163|M.ulcerans_Agy99 -
MAV_4919|M.avium_104 G
MLBr_02568|M.leprae_Br4923 -
Mflv_0414|M.gilvum_PYR-GCK S
MSMEG_0363|M.smegmatis_MC2_155 -
TH_0452|M.thermoresistible__bu -
MAB_1149|M.abscessus_ATCC_1997 -
Mvan_0929|M.vanbaalenii_PYR-1 -