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TQTTTASATTTGLLEGKIAFITGAGRGIGAAAARLFAAEGASVMLAARTEAQLEEVTEQIRADGGTAEYV VCDQADPDTVRAAVNRTVEVWGRLDVAFNNGATIQPPGPLDGLPEADLDRIYDVNFKGVWLALAAEIAAI RATSKTGAIVNTSSIGSLQGNPELPAYGAMKRALNSLTESAAVTYGPEGIRVNTIAPGTTLTEMIDEWDA ASPGTIDRLVSIAPLGRAAAPAEIAEAAAWLLSDRASYVTGVTLRVDGGTGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1630 | - | - | 100% (263) | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5584 | - | 2e-39 | 41.53% (248) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2477 | - | 7e-38 | 40.32% (248) | cyclopentanol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 3e-35 | 38.71% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1825 | - | 9e-37 | 39.92% (248) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 3e-35 | 38.71% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-20 | 29.70% (266) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4632 | - | 3e-36 | 40.08% (247) | short chain dehydrogenase |
| M. marinum M | MMAR_4581 | - | 8e-35 | 39.11% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1046 | - | 5e-37 | 40.73% (248) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3898 | - | 5e-38 | 40.73% (248) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4442 | - | 2e-34 | 39.11% (248) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3997 | - | 2e-36 | 37.66% (239) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1825|M.gilvum_PYR-GCK ----MILDRFR-------LDDQVAVVTGAGRGLGAAMALAFAEAGADVLI
TH_3898|M.thermoresistible__bu ----VILDRFR-------LDDRVAVVTGAGRGLGAAMAVAFAEAGADVLI
MMAR_4581|M.marinum_M ----MILDRFR-------LDDQVAVITGGGRGLGAAIALAFAEAGADVVI
MUL_4442|M.ulcerans_Agy99 ----MILDRFR-------LDDQVAVITGGGRGFGAAIALAFAEAGADVVI
MAV_1046|M.avium_104 ----MILDRFR-------LDDKVAVITGAGRGLGAAIAVAFAEAGADVLI
MAB_4632|M.abscessus_ATCC_1997 ----MILDRFK-------LDGNVAVVTGAGRGLGAAIAEAFAQAGADVLI
Mb2788c|M.bovis_AF2122/97 ------MTSLD-------LTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv ------MTSLD-------LTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MSMEG_1630|M.smegmatis_MC2_155 ----MTQTTTASATTTGLLEGKIAFITGAGRGIGAAAARLFAAEGASVML
Mvan_3997|M.vanbaalenii_PYR-1 -----MDDRY---------IDTTVLVTGAASGIGRAIAFAAAREGARLIL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
. .:**. *:* * * . * : :
Mflv_1825|M.gilvum_PYR-GCK AARTQSQLEAVAEQIAGTGRRAHIVVADLARPEDTAGLAAQAVEAFGRLD
TH_3898|M.thermoresistible__bu SARTQAQLEEVAAQIAATGRRAHVVAADLAHPEATAELAGAAVEAFGKLD
MMAR_4581|M.marinum_M ASRTQSQLDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLD
MUL_4442|M.ulcerans_Agy99 ASRTQSQLDEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLD
MAV_1046|M.avium_104 ASRTESQLEAVAEQVRAAGRRAHVVAADLAHPESTAELAGRAVEAFGKLD
MAB_4632|M.abscessus_ATCC_1997 ASRTESQLREVAAKVQAAGRQAEVVVADLSDTEASAALAQKAVDRFGRLD
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQVG---DRALGVGAHAVDEDAARRCVDLTLERFGSVD
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQVG---DRALGVGAHAVDEDAARRCVDLTLERFGSVD
MSMEG_1630|M.smegmatis_MC2_155 AARTEAQLEEVTEQIRADGGTAEYVVCDQADPDTVRAAVNRTVEVWGRLD
Mvan_3997|M.vanbaalenii_PYR-1 GDITVDRLADAAEELRARGAQVVHARCDITSTADLESLVQRGSHELGPVD
MLBr_01807|M.leprae_Br4923 THRAS-----------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
. .. . * ::
Mflv_1825|M.gilvum_PYR-GCK IVVNNVGG-TMPNALLNTSTKDMRDAFTFNVATAHALTTAAVPLMLEHSG
TH_3898|M.thermoresistible__bu IVVNNVGG-TMPGPLLNTSAKEMRDAFTFNVGTAHALTTAAVPLMLKHSG
MMAR_4581|M.marinum_M IVVNNVGG-TMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSG
MUL_4442|M.ulcerans_Agy99 IVVNNVGG-TMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSG
MAV_1046|M.avium_104 IVVNNVGG-TMPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSG
MAB_4632|M.abscessus_ATCC_1997 VVVNNVGG-TMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLK-SD
Mb2788c|M.bovis_AF2122/97 ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG-EH
Rv2766c|M.tuberculosis_H37Rv ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG-EH
MSMEG_1630|M.smegmatis_MC2_155 VAFNNGATIQPPGPLDGLPEADLDRIYDVNFKGVWLALAAEIAAIRATSK
Mvan_3997|M.vanbaalenii_PYR-1 VAFANAGVLGSPGDVWSYSEDEFTRILDINVTGTWRTVRAVLPAMIE-RR
MLBr_01807|M.leprae_Br4923 VLVANAGI-TSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK-QR
: . * . . : .*.
Mflv_1825|M.gilvum_PYR-GCK GGSIINITSTMGRVAGRGFAAYGTAKAALAHYTRLSALDLAPR-IRVNAI
TH_3898|M.thermoresistible__bu GGSIINITSTMGRLAGRGFAAYGTAKAALAHYTRLAALDLAPR-IRVNAI
MMAR_4581|M.marinum_M GGSIINITSTMGRVAGRGFAAYGTAKAALAHYTRLAALDLCPR-IRVNAI
MUL_4442|M.ulcerans_Agy99 GGGIINITSTMGRVAGRGFAAYGTAKVALAHYTRLAALDLCPR-IRVNAI
MAV_1046|M.avium_104 GGNIINITSTMGRLAGRGFAAYGTAKAALSHYTRLTALDLCPR-IRVNAI
MAB_4632|M.abscessus_ATCC_1997 NASVINITSTMGRLPGRAFLGYCTAKGALAHYTRTAAMDLSPR-IRVNGI
Mb2788c|M.bovis_AF2122/97 GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
Rv2766c|M.tuberculosis_H37Rv GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
MSMEG_1630|M.smegmatis_MC2_155 TGAIVNTSSIGSLQGNPELPAYGAMKRALNSLTESAAVTYGPEGIRVNTI
Mvan_3997|M.vanbaalenii_PYR-1 RGIIVATASAAGLIGPAGLPAYVASKHAVVGLVKSTAMNVAAHGIRVNAL
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
. : * . * : * .: .. * .. * .* :
Mflv_1825|M.gilvum_PYR-GCK APGSILTSALEIVASNDD-LRDPMEKATPMKRLGDPLDIAAAAVYLASPA
TH_3898|M.thermoresistible__bu APGSILTSALDVVASNDE-LRTPMEQATPLRRLGEPADIAAAAVYLASPA
MMAR_4581|M.marinum_M APGSILTSALEVVAANDE-LRAPMEQATPLRRLGDPVDIAAAAVYLASPA
MUL_4442|M.ulcerans_Agy99 APGSILTSALEVVAANDE-LRAPMEQATPLRRLGDPVDIAAAAVYLASPA
MAV_1046|M.avium_104 APGSILTSALDVVASNDE-LRAPMEKATPLRRLGDPVDIASAAVYLASPA
MAB_4632|M.abscessus_ATCC_1997 APGSILTSALEVVAGNDE-MRNTLEQNTPLHRLGDPADIAAAAVYLASPA
Mb2788c|M.bovis_AF2122/97 CPGVVRTRLAEALWKDH---EDPLAATIALGRIGEPADIASAVAFLVSDA
Rv2766c|M.tuberculosis_H37Rv CPGVVRTRLAEALWKDH---EDPLAATIALGRIGEPADIASAVAFLVSDA
MSMEG_1630|M.smegmatis_MC2_155 APGTTLTEMIDEWDAASPGTIDRLVSIAPLGRAAAPAEIAEAAAWLLSDR
Mvan_3997|M.vanbaalenii_PYR-1 CPHMVDTPMLDKVSHEIPGLRESLDQQTPLGRVATSEEVARSALWLGSDE
MLBr_01807|M.leprae_Br4923 APGFIDTEMTRAMDSKYQ---EAALQAIPLGRIGAVEEIAGAVSFLASED
.* * .: * . ::* :. :* *
Mflv_1825|M.gilvum_PYR-GCK GSYLTGKTLEVDGGITFPN----LELPIPDL-
TH_3898|M.thermoresistible__bu GSYLTGKVLEVDGGLTRPN----LDMPIPDL-
MMAR_4581|M.marinum_M GSFLTGKTLEVDGGLTHPN----LDIPVPDL-
MUL_4442|M.ulcerans_Agy99 GSFLTGKTLEVDGGLTHPN----LDIPVPDL-
MAV_1046|M.avium_104 GEFLTGKTLEVDGGLTYPN----LDIPVPDL-
MAB_4632|M.abscessus_ATCC_1997 GSFLTGKVLEVDGGLIAPN----LDIPLPDLA
Mb2788c|M.bovis_AF2122/97 ASWITGETMIIDGGLLLGNALGFRAAPSTEH-
Rv2766c|M.tuberculosis_H37Rv ASWITGETMIIDGGLLLGNALGFRAAPSTEH-
MSMEG_1630|M.smegmatis_MC2_155 ASYVTGVTLRVDGGTGV---------------
Mvan_3997|M.vanbaalenii_PYR-1 SSFVTGHALLVDGGLVAQ--------------
MLBr_01807|M.leprae_Br4923 AGYISGAVIPVDGGLGMGH-------------
. :::* .: :***