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MNFDWTFFWKSLLTPSDAFLQGLVLTIVISVVAMVLATVAGLIVALMRRSRLPAVRWVAGVYIWVIRGTP LLVQLVLIYTGLAAAGLYQFHDVSLLGLSVKAALQAAIIGLMINESAYIAEIIRAGLDSVPKGQFEAAAS LGMKPAKVMRWIIVPQALRVMVPPMGNSFNGLMKTTSVLSVIGVSEMFLVTQSISSATFHTFEIFIVAAI YYLALTTIWTFIQAGIENRLARQLGIEQRVPITQRLLGARRAAAAPLEPAGVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1613 | - | - | 100% (263) | ABC polar amino acid transporter, inner membrane subunit |
| M. smegmatis MC2 155 | MSMEG_6594 | - | 6e-43 | 43.52% (216) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. smegmatis MC2 155 | MSMEG_0177 | - | 8e-40 | 37.45% (235) | ABC polar amino acid family protein transporter, inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2421c | cysT | 3e-05 | 22.53% (182) | sulfate-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3582 | - | 3e-36 | 35.09% (265) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv2399c | cysT | 3e-05 | 22.53% (182) | sulfate-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0277c | - | 4e-32 | 35.85% (212) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 3e-23 | 29.06% (234) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 2e-23 | 30.15% (262) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_0515 | - | 6e-28 | 31.42% (261) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | MUL_3660 | cysT | 4e-05 | 25.56% (180) | sulfate-transport integral membrane protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2833 | - | 3e-35 | 35.00% (240) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
TH_0515|M.thermoresistible__bu --VTRAAVVAVIALLVGSLTAGG--TVLAAPAAATVDQCAPPGVQSASPL
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2421c|M.bovis_AF2122/97 --------------------------------------------------
Rv2399c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3660|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
TH_0515|M.thermoresistible__bu PTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGTLSDAP
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2421c|M.bovis_AF2122/97 --------------------------------------------------
Rv2399c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3660|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 ---------------MFRAIVLALLALVAVAGCAAPTQEPLRVGTEGVYA
MMAR_0061|M.marinum_M PNTCIN-STGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRF
MAV_0059|M.avium_104 PNVCIT-PTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRF
TH_0515|M.thermoresistible__bu PSICIN-SLGEFTGFDNELLRAIAAKLGLQISFVGTEFSALLAQVASGRF
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2421c|M.bovis_AF2122/97 --------------------------------------------------
Rv2399c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3660|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 PFSFHDGHTGELTGYDVDVARAVGEKLGRPVEFVEIPWDAIFAGLDAERF
MMAR_0061|M.marinum_M DVGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRI
MAV_0059|M.avium_104 DVGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRI
TH_0515|M.thermoresistible__bu DVGSSSITTTEQRRRTVEFTNGYDFGYFSLVVPSGSAITGFGDLVPGQRI
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2421c|M.bovis_AF2122/97 --------------------------------------------------
Rv2399c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3660|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 DVVANQVTITPARKAKYDISTPYAVG-EGVIVTRADDNSIHSLSDVRGKV
MMAR_0061|M.marinum_M GVVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEA
MAV_0059|M.avium_104 GVVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAAT
TH_0515|M.thermoresistible__bu GVVQGTVQESYVVDTLGLRPVIFPDYNTVYASLKTRQIDAWVAPSQQAEG
Mflv_3582|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2421c|M.bovis_AF2122/97 ------------------------------------------MTESLVGE
Rv2399c|M.tuberculosis_H37Rv ------------------------------------------MTESLVGE
MUL_3660|M.ulcerans_Agy99 ------------------------------------------MTVTAHSG
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 AAENATSNWSQIARDAGARVEAVEGFTQSITLLSQGRVDVVINDSIAVYA
MMAR_0061|M.marinum_M AIRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWS
MAV_0059|M.avium_104 TIQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWS
TH_0515|M.thermoresistible__bu TVRPGDPAEIIENTFSLDNFIAYAVAPGNQPLIDALNAGLDAVIADGTWA
Mflv_3582|M.gilvum_PYR-GCK -----------------------MTNEAGSPPTSGTPQSIDAVPLRHPWR
Mvan_2833|M.vanbaalenii_PYR-1 -----------------------MT-DVGAPPPSSSPQSIDAIPLKHPWR
Mb2421c|M.bovis_AF2122/97 RR-----APQFRAR-------LSGP-----AGPPSVRVGMAVVWLS----
Rv2399c|M.tuberculosis_H37Rv RR-----APQFRAR-------LSGP-----AGPPSVRVGMAVVWLS----
MUL_3660|M.ulcerans_Agy99 QSDPPAVAPDLGQRADGGPQWISGPGRSGRRGATALQVGVSMVWLS----
MSMEG_1613|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 YLASTGDPAVKIAGATGQRSEQGFAARKNSGLLPDLDKALDQLAADGTLT
MMAR_0061|M.marinum_M QLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAA--HRHKPVGPAAPK
MAV_0059|M.avium_104 NLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAAS--QHHKAVGPAAPK
TH_0515|M.thermoresistible__bu RLYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAERASQQPAAGPGVRK
Mflv_3582|M.gilvum_PYR-GCK --------------WVAAAVIIVLVGLFLWGAATND--------------
Mvan_2833|M.vanbaalenii_PYR-1 --------------WLAAAAIIVLVGLFLYGAATNP--------------
Mb2421c|M.bovis_AF2122/97 ------------------VIVLLPLAAIVWQAAGGG--------------
Rv2399c|M.tuberculosis_H37Rv ------------------VIVLLPLAAIVWQAAGGG--------------
MUL_3660|M.ulcerans_Agy99 ------------------VIVLLPLAAIAWQAADGG--------------
MSMEG_1613|M.smegmatis_MC2_155 -------------------------MNFDWTFFWKS--------------
MAB_0277c|M.abscessus_ATCC_199 RISQKYLKT------DASGTTKPQAGKGDSGSTRSD--------------
MMAR_0061|M.marinum_M SALTQLRDSFFDWDMYRQAIP-TLFKTGLPNTLILTLSASIIGLALGMAL
MAV_0059|M.avium_104 STLAQLRDSFFDWDMYRQAIP-TLLRTGLPNTLILTFSASVIGLVLGMVL
TH_0515|M.thermoresistible__bu STLAQLADSFLDWELYRQAIP-DLLTTGLPNTLLLTVGAGVIGLVLGMVL
Mflv_3582|M.gilvum_PYR-GCK ---------AYGWSTYAEYLFNERILLGVFNTIQLTVYSMVIGIVLGVIL
Mvan_2833|M.vanbaalenii_PYR-1 ---------AYGWSTFGEYFFHERILLGVFNTLQLTIYSMIIGIVLGVFL
Mb2421c|M.bovis_AF2122/97 ------------WRAFWLAVSSHAAMESFRVTLTISTAVTVINLVFGLLI
Rv2399c|M.tuberculosis_H37Rv ------------WRAFWLAVSSHAAMESFRVTLTISTAVTVINLVFGLLI
MUL_3660|M.ulcerans_Agy99 ------------WHAFWLSVSSHAALESLRVTLTVSAGVTLLNAVFGLLI
MSMEG_1613|M.smegmatis_MC2_155 -----------------LLTPSDAFLQGLVLTIVISVVAMVLATVAGLIV
MAB_0277c|M.abscessus_ATCC_199 -------------TQLVLDNLWPMARAMITVTLPLTAISFVIGLVIALGV
. *: :: :: . .: :
MMAR_0061|M.marinum_M AIAGISHQRWLRWPARVYTDIFRG------------LPEVVIILIIGLGV
MAV_0059|M.avium_104 AVAGISHARWLRWPARVYTDVFRG------------LPEVVIILLIGLGI
TH_0515|M.thermoresistible__bu AIAGISRSRLLRWPARVYTDIFRG------------LPEVVIILLIGLGL
Mflv_3582|M.gilvum_PYR-GCK TIMRLSSNPVLSSVAWVFLWIFRGTPVYVQLAFWGLMPTIYQNIQLGVPF
Mvan_2833|M.vanbaalenii_PYR-1 TVMRLSDNPVLSSVAWVFLWIFRGTPIYVQLAFWGLFPTIYQNIQLGVPF
Mb2421c|M.bovis_AF2122/97 AWVLVRDDFAGKRIVDAIIDLPFA------------LPTIVASLVMLALY
Rv2399c|M.tuberculosis_H37Rv AWVLVRDDFAGKRIVDAIIDLPFA------------LPTIVASLVMLALY
MUL_3660|M.ulcerans_Agy99 AWGLIRDEFVGKRLVDAVIDLPFA------------LPTIVASLVMLALY
MSMEG_1613|M.smegmatis_MC2_155 ALMRRSRLPAVRWVAGVYIWVIRG------------TPLLVQLVLIYTGL
MAB_0277c|M.abscessus_ATCC_199 ALARMSGHRVVTGLARIYISVIRG------------TPLLLQLFLIFFAL
: . : . * : . :
MMAR_0061|M.marinum_M G-PIVGGLTNNN--------PYPLGIAALGLMAGAYVGEILRSGIQSVDP
MAV_0059|M.avium_104 G-PIVGGLTNNN--------PYPLGIAALGMMAAAYIGEILRSGIQSVDP
TH_0515|M.thermoresistible__bu G-PVVGGLTGYN--------PFPLGILALGLMAAAYVGEILRSGIQSVEP
Mflv_3582|M.gilvum_PYR-GCK G-PSLLHFDLQDLS-----FPFALAVIGLALNEAAYMAEIVRAGITSVPE
Mvan_2833|M.vanbaalenii_PYR-1 G-PSFFHLDLQDLS-----IPFVLAVIGLGLNEAAYMAEIVRAGIMSVPE
Mb2421c|M.bovis_AF2122/97 GNNSPVGLHFQH--------TATGVGVALAFVTLPFVVRAVQPVLLEIDR
Rv2399c|M.tuberculosis_H37Rv GNNSPVGLHFQH--------TATGVGVALAFVTLPFVVRAVQPVLLEIDR
MUL_3660|M.ulcerans_Agy99 GHNSPLGLHLQH--------TVWGVGVALAFVTLPFVVRAVQPVLLELDR
MSMEG_1613|M.smegmatis_MC2_155 AAAGLYQFHDVSLLGLSVKAALQAAIIGLMINESAYIAEIIRAGLDSVPK
MAB_0277c|M.abscessus_ATCC_199 P---EFGVKISP---------FPAAVIAFSLNVGGYAAEIIRSSILSIPR
. .: : : . ::. : .:
MMAR_0061|M.marinum_M GQLEASRALGFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFL
MAV_0059|M.avium_104 GQLEASRALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFL
TH_0515|M.thermoresistible__bu GQLEAARALGFSYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFL
Mflv_3582|M.gilvum_PYR-GCK GQLEASTALGMSWGRAMRRTVLPQAMRVIIPPTGNEVISLLKTTSLVTAV
Mvan_2833|M.vanbaalenii_PYR-1 GQMEASTALGMSWGKAMRRTVLPQAMRVIIPPTGNELISLLKTTSLVTAV
Mb2421c|M.bovis_AF2122/97 ETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLI
Rv2399c|M.tuberculosis_H37Rv ETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLI
MUL_3660|M.ulcerans_Agy99 ETEEAAASLGATGWKVFTSVIFPSLMPALLSGAGLAFSRAIGEFGSVVLI
MSMEG_1613|M.smegmatis_MC2_155 GQFEAAASLGMKPAKVMRWIIVPQALRVMVPPMGNSFNGLMKTTSVLSVI
MAB_0277c|M.abscessus_ATCC_199 GQWEAASSLGMSYSTTLWRIVIPQASRVAVPPLSNTLISLVKDTSLASAI
**: :** . : :.*. :. . : . :
MMAR_0061|M.marinum_M G-LIAQQRELFQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDA
MAV_0059|M.avium_104 G-LVADQRELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDA
TH_0515|M.thermoresistible__bu G-LVADQRELFQVGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDN
Mflv_3582|M.gilvum_PYR-GCK P-YAFDLYSIATREIAARIFEP-VPLLLVAATWYLVITSILMVGQFYLER
Mvan_2833|M.vanbaalenii_PYR-1 P-YAFDVYSIATREIAARIFEP-VPLLLVAAAWYLVITSILMVGQFYLER
Mb2421c|M.bovis_AF2122/97 GGAVPGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFIVLLILRVVGA
Rv2399c|M.tuberculosis_H37Rv GGAVPGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFIVLLILRVVGA
MUL_3660|M.ulcerans_Agy99 GGAVPGETEVSSQWIRTLIENDDRTGAAAISIVLLSISFAVLLVLRVLGA
MSMEG_1613|M.smegmatis_MC2_155 G----VSEMFLVTQSISSATFHTFEIFIVAAIYYLALTTIWTFIQAGIEN
MAB_0277c|M.abscessus_ATCC_199 L----VTDVMRTAQVAAAPTFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQ
. . . : :
MMAR_0061|M.marinum_M RLRRGRRRLDPEDPPGVVSSTIGEEMT--------
MAV_0059|M.avium_104 RLRRGRAAVDPEEPAEMLT--FGQEIT--------
TH_0515|M.thermoresistible__bu RLRRGRK-PAAEDPLEPAT---AQEMI--------
Mflv_3582|M.gilvum_PYR-GCK YFSRGVSRQLTSKQLEALAKAQLGSAVP-------
Mvan_2833|M.vanbaalenii_PYR-1 YFSRGASRKLTSKQLEALALAQLPQVK--------
Mb2421c|M.bovis_AF2122/97 RAAKREEMAA-------------------------
Rv2399c|M.tuberculosis_H37Rv RAAKREEMAA-------------------------
MUL_3660|M.ulcerans_Agy99 RAAKREELAP-------------------------
MSMEG_1613|M.smegmatis_MC2_155 RLARQLGIEQRVPITQRLLGARRAAAAPLEPAGVR
MAB_0277c|M.abscessus_ATCC_199 RLEKSVAR---------------------------
: