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M. bovis AF2122 / 97 Mb2323 (cut2)

annotation: cutinase CUT2
coordinates: 2550610 - 2551302
length: 230

VNDLLTRRLLTMGAAAAMLAAVLLLTPITVPAGYPGAVAPATAACPDAEVVFARGRFEPPGIGTVGNAFV
SALRSKVNKNVGVYAVKYPADNQIDVGANDMSAHIQSMANSCPNTRLVPGGYSLGAAVTDVVLAVPTQMW
GFTNPLPPGSDEHIAAVALFGNGSQWVGPITNFSPAYNDRTIELCHGDDPVCHPADPNTWEANWPQHLAG
AYVSSGMVNQAADFVAGKLQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2323cut2-100% (230)cutinase CUT2
M. bovis AF2122 / 97Mb3482cut45e-5553.10% (226) cutinase precursor CUT4
M. bovis AF2122 / 97Mb3481cut32e-4242.29% (227) cutinase precursor CUT3

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4967-7e-7758.70% (230) cutinase
M. tuberculosis H37RvRv2301cut21e-135100.00% (230) cutinase CUT2
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3763-8e-5145.45% (231) cutinase cut2 precursor
M. marinum MMMAR_2908-1e-9269.83% (232) cutinase precursor
M. avium 104MAV_2759-3e-8376.80% (181) serine esterase, cutinase family protein
M. smegmatis MC2 155MSMEG_1526-5e-8669.95% (213) cutinase
M. thermoresistible (build 8)TH_3765-1e-8063.84% (224) PUTATIVE Cutinase
M. ulcerans Agy99MUL_0855cut47e-4845.85% (229) cutinase precursor, Cut4
M. vanbaalenii PYR-1Mvan_1439-3e-7660.62% (226) cutinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2323|M.bovis_AF2122/97            MNDLLTRR----------LLTMGAAAAMLAAVLLLTPITVPAGYPGAV--
Rv2301|M.tuberculosis_H37Rv         MNDLLTRR----------LLTMGAAAAMLAAVLLLTPITVPAGYPGAV--
MMAR_2908|M.marinum_M               MRALFARR----------SVQFGVGAVAVAAALTIAAAVLPPGTPGAA--
MAV_2759|M.avium_104                --------------------------------------------------
MSMEG_1526|M.smegmatis_MC2_155      MVEHSSSP----------QLLKWLSAVVIVAATAVALVVAPTVTTRGL--
Mflv_4967|M.gilvum_PYR-GCK          MIRQLRNL----------RVPYLVVALLFGAASLILP-------------
Mvan_1439|M.vanbaalenii_PYR-1       MIRQLRKF----------PVLSALAALLSTAAALVAP-------------
TH_3765|M.thermoresistible__bu      MVGTMGEVNSDLELPGTRRTVALLTAALFLAAGLVTGSAVSPASAPLA--
MAB_3763|M.abscessus_ATCC_1997      MTLQPNPR----------PASKLLTAAARAAVVSVAAIMLTTGLAVVI--
MUL_0855|M.ulcerans_Agy99           MWLFPLDAQK------WARSGRGRTRLARRCAGLVATTIAACAVLLAFPL
                                                                                      

Mb2323|M.bovis_AF2122/97            APATAA-CPDAEVVFARGRFEPPGIGTVGNAFVSALRSKVN-KNVGVYAV
Rv2301|M.tuberculosis_H37Rv         APATAA-CPDAEVVFARGRFEPPGIGTVGNAFVSALRSKVN-KNVGVYAV
MMAR_2908|M.marinum_M               PSTDAANCPQVEVVFARGRFESPGPGVLGNAFISSLSSKVGGRSMGSYAV
MAV_2759|M.avium_104                ----------MQVVFARGRNESPGPGVLGNAFISALRSRVN-RTVGVYAV
MSMEG_1526|M.smegmatis_MC2_155      PMAGAAPCADVEVIFARGRTEPAGVGTLGNAFVNALRPKVK-KSMNVYAV
Mflv_4967|M.gilvum_PYR-GCK          PAASAQACPQAELIFARGRIESPGAGVIGNALASALRNKTG-RDIDLYAV
Mvan_1439|M.vanbaalenii_PYR-1       PLASAQACPEVELIFARGRIESPGAGQIGNALVSALRSKTG-KSVDLYAV
TH_3765|M.thermoresistible__bu      PVAQAAPCPDVEVIFARGRVESPGPGIIGNAFVNSLRSKTD-KNVSLYAV
MAB_3763|M.abscessus_ATCC_1997      PATASAACPNVEVSFARGRSQPPGLGNIGDAFVSALRNRVK--NLSVYAV
MUL_0855|M.ulcerans_Agy99           VPKAAAACPDVQVVFARGTGEPPGLGRVGNAMVASLRQKTD-QSIGAYAV
                                               :: ****  :..* * :*:*:  :*  :.    :. ***

Mb2323|M.bovis_AF2122/97            KYPADN---QIDVGANDMSAHIQSMANSCPNTRLVPGGYSLGAAVTDVVL
Rv2301|M.tuberculosis_H37Rv         KYPADN---QIDVGANDMSAHIQSMANSCPNTRLVPGGYSLGAAVTDVVL
MMAR_2908|M.marinum_M               KYPADT---EVDIGANDMSGHIQYMVNSCPDTRLVLGGYSLGAAVTDVVL
MAV_2759|M.avium_104                QYPADT---EVAQGANDMSRHIQDMVNSCPDTRLVLGGYSLGAAVTDVVL
MSMEG_1526|M.smegmatis_MC2_155      KYPADT---EVDVGANDMSNRIKYMMDNCPNTRLVIGGYSLGAAVADVVL
Mflv_4967|M.gilvum_PYR-GCK          KYPADT---EVDIGANDMSQRIQYMARNCPDTRLVLGGYSLGAAVTDIVI
Mvan_1439|M.vanbaalenii_PYR-1       KYPADT---EVDLGANDMSQRIQYMAGNCPDTRLVLGGYSLGAAVTDVVV
TH_3765|M.thermoresistible__bu      QYPADY---EIDIGANDMSRRIQHMAATCPDTRLVLGGYSLGAAVTDVVL
MAB_3763|M.abscessus_ATCC_1997      RYDANT---DVGGGANDLSAHLQQTANNCPDTKLVVGGYSLGAGVVDTAL
MUL_0855|M.ulcerans_Agy99           NYPANKDFLAAADGANDASDHVQQMTNECPNTKLVLGGYSQGAAVINIVT
                                    .* *:        **** * :::     **:*:** **** **.* : . 

Mb2323|M.bovis_AF2122/97            AVP-----TQMWGFTNPLPPGSDEHIAAVALFGNGSQWVGPITNFS-PAY
Rv2301|M.tuberculosis_H37Rv         AVP-----TQMWGFTNPLPPGSDEHIAAVALFGNGSQWVGPITNFS-PAY
MMAR_2908|M.marinum_M               AVP-----MSAFGFENPLPPGTDQHIAAVALFGNGSQWVGPITNFS-PLY
MAV_2759|M.avium_104                AAP-----IGAFGFDSPLPPGVDQHIAAVALFGNGSQWVGPITNFN-PTY
MSMEG_1526|M.smegmatis_MC2_155      AVP-----FTAFGFKNPLPAGADQHIAAVALFGNGAAWVGPITNFS-PVY
Mflv_4967|M.gilvum_PYR-GCK          AVP-----IAAFGFKNPLPDGVDRHIAAVALFGNGSQWVGPIANFTNPAL
Mvan_1439|M.vanbaalenii_PYR-1       AVP-----IAAFGFKSPLPDGVDRHIAAVALFGNGSQWVGPIANFTNPAL
TH_3765|M.thermoresistible__bu      AVP-----ISALGFDSPLPAGVDRHIAAIALFGNGIAWAGPISNFS-PLY
MAB_3763|M.abscessus_ATCC_1997      GVPGPVQIGNLFSFDNPVPPEVGDHIRAIVTFGNIVNRFAPVQSLA-GAY
MUL_0855|M.ulcerans_Agy99           AAP-----LPGLGFTQPLPAQAAQHVAAVTLFGNPSGRAGGLMTALSPHF
                                    ..*         .* .*:*     *: *:. ***     . : .      

Mb2323|M.bovis_AF2122/97            NDRTIELCHGDDPVCHPADPNTWEANWPQHLAGAYVSSGMVNQAADFVAG
Rv2301|M.tuberculosis_H37Rv         NDRTIELCHGDDPVCHPADPNTWEANWPQHLAGAYVSSGMVNQAADFVAG
MMAR_2908|M.marinum_M               NDRTIELCHGADPICSPADPNTWKQNWPQHLASAYIQDGMVNEAADFVAG
MAV_2759|M.avium_104                NDRTIELCHGADPICNPADPNTWKQNWPQHLAGAYIDAGMADQAADFVAG
MSMEG_1526|M.smegmatis_MC2_155      NDRTIELCHGADPICNPADPNTWQNNWPDHLAGAYISGGMVNQAADFVAS
Mflv_4967|M.gilvum_PYR-GCK          RDRIVELCHGDDPICNPTAPENWQDNWPAHLASAYVGAGMVNQAADFIVG
Mvan_1439|M.vanbaalenii_PYR-1       RDRIIELCHGDDPICNPTAPENWQDYWPAHLAPAYIGAGMVNQAADFIVG
TH_3765|M.thermoresistible__bu      AERTIELCHGADPICNPADPETWRDNWSDHAATKYVQSGMVDQAADFVAA
MAB_3763|M.abscessus_ATCC_1997      GDRVLDLCNDGDPVCMDGNQDTWKS----HTS---YPPALINQAADFAAA
MUL_0855|M.ulcerans_Agy99           GGKILNLCNTGDPICSDGDQ------WKAHTG---YVPGLTNKAASFVAG
                                      : ::**:  **:*              * .      .: ::**.* ..

Mb2323|M.bovis_AF2122/97            KLQ
Rv2301|M.tuberculosis_H37Rv         KLQ
MMAR_2908|M.marinum_M               KL-
MAV_2759|M.avium_104                KL-
MSMEG_1526|M.smegmatis_MC2_155      KL-
Mflv_4967|M.gilvum_PYR-GCK          RL-
Mvan_1439|M.vanbaalenii_PYR-1       RL-
TH_3765|M.thermoresistible__bu      RL-
MAB_3763|M.abscessus_ATCC_1997      RVN
MUL_0855|M.ulcerans_Agy99           RI-
                                    ::