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TTTVLAYIPSPPQGVWYLGPFPLRAYALCIIVGIVAALVIGDRRWVARGGEPGVIYDIALWAVPFGLIGG RLYHVITDWPTYFGDGGAGPAAALRIWDGGLGIWGAVALGAVGAWIACRRRGIPLPAFGDAIAPGIVLAQ AIGRLGNYFNQELYGRETTVPWGLEIYERRNSAGVLDSLNGISTGELIGVVHPTFLYELLWNLLVFAVLI LVDRRFKIGHGRLFALYVAGYCAGRFWIELMRSDTATLLAGIRVNTFTATFVFVAAVVYVIVAPKGREAP ESLRGNQDAESDVEDLAKDVALASAVGVVAAATVAGEDEKRDGGGSPPGGLGSVEGDEALEAAGGASAAN ESAVEGAADAADLVALLEASEDVEVADGAVEPQEVDAPPVPDEAGGLGAVEGEEAAEAAAGAGAARASVS DDAEASNDADAETEAAGLGSVDGDEVAAAVEDAPEVHEAAVEGEAEAEELAAEAEVEAVAAEVAEVDADA LTGADDDVDAETEAAVEGEAEAEELAAEADAEAQVAAEVAEVDADALTGADDDVDAETEAEVEGEAEAEE LAAEADAEAQVAAEVAEVDAETLTGADKDVDAEALTDADAETEAAGLGSVDGDEVAAAVEDAPEVHEAAV EGESEAEELAAEADAEALAEVAEIDAEAVNDADEDVDAEAEAEAAGLGSVDGDEVAAAVEDAPEVREAVE GVAEVDAEALTDAEPEESDAEGEPEGPALPTSEHSPYTVVTESSSEPAQSGPAGLVRQWIRRRRNR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3597 | - | - | 100% (767) | prolipoprotein diacylglyceryl transferase |
M. gilvum PYR-GCK | Mflv_0078 | - | 4e-15 | 30.46% (325) | hypothetical protein Mflv_0078 |
M. gilvum PYR-GCK | Mflv_4188 | - | 2e-13 | 30.35% (425) | chromosome segregation protein SMC |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1640 | lgt | 1e-135 | 55.48% (465) | prolipoprotein diacylglyceryl transferase |
M. tuberculosis H37Rv | Rv1614 | lgt | 1e-135 | 55.48% (465) | prolipoprotein diacylglyceryl transferase |
M. leprae Br4923 | MLBr_01274 | - | 1e-127 | 66.15% (325) | putative prolipoprotein diacylglyceryl transferase |
M. abscessus ATCC 19977 | MAB_2642c | - | 1e-131 | 67.85% (339) | prolipoprotein diacylglyceryl transferase |
M. marinum M | MMAR_2416 | lgt | 1e-165 | 47.17% (778) | prolipoprotein diacylglyceryl transferases Lgt |
M. avium 104 | MAV_3172 | - | 1e-137 | 56.86% (459) | prolipoprotein diacylglyceryl transferase |
M. smegmatis MC2 155 | MSMEG_3222 | - | 1e-164 | 56.09% (608) | prolipoprotein diacylglyceryl transferase |
M. thermoresistible (build 8) | TH_1073 | lgt | 1e-142 | 75.00% (324) | Possible prolipoprotein diacylglyceryl transferases Lgt |
M. ulcerans Agy99 | MUL_2033 | smc | 2e-08 | 26.96% (345) | chromosome partition protein Smc |
M. vanbaalenii PYR-1 | Mvan_2819 | - | 0.0 | 57.86% (859) | prolipoprotein diacylglyceryl transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1640|M.bovis_AF2122/97 ------MRMLPSYIPSPPRGVWYLGPLPVR---AYAVCVITGIIVALLIG Rv1614|M.tuberculosis_H37Rv ------MRMLPSYIPSPPRGVWYLGPLPVR---AYAVCVITGIIVALLIG MLBr_01274|M.leprae_Br4923 -----MTRMLPGYFPSPPRGVWHLGPLPIR---AYALLIILGIVAALVVG MMAR_2416|M.marinum_M -----MTATVLAYFPSPPRGVWHLGPLPIR---AYAFFIIIGIVMGLMIG MAV_3172|M.avium_104 ------MTKLLAYFPSPPQGVWHLGPVPIR---AYALFIIAGIVAALLIG Mflv_3597|M.gilvum_PYR-GCK -----MTTTVLAYIPSPPQGVWYLGPFPLR---AYALCIIVGIVAALVIG Mvan_2819|M.vanbaalenii_PYR-1 -----MTTTVLAYIPSPSQGVWHLGPFPVR---AYALFIIVGIIAALVIG MAB_2642c|M.abscessus_ATCC_199 -----MTVVNLAYIPSPPQGVWHLGPIPIR---AYALCIIAGIVAALIIG TH_1073|M.thermoresistible__bu ------VTTTLAYIPSPAQGVWQLGPIPIR---AYALCIIAGIVVALVLG MSMEG_3222|M.smegmatis_MC2_155 -----MTTTVLAYLPSPSQGVWHLGPVPIR---AYALCIIVGIVAALVIG MUL_2033|M.ulcerans_Agy99 MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE :.:*. : * .: . . : . : :: Mb1640|M.bovis_AF2122/97 DRRLTARGG-ERGMTYDIALWAVPFG----------------------LI Rv1614|M.tuberculosis_H37Rv DRRLTARGG-ERGMTYDIALWAVPFG----------------------LI MLBr_01274|M.leprae_Br4923 GRCWEARGG-ERDVTYDIALWAVPFG----------------------LV MMAR_2416|M.marinum_M DRRFAARGG-ERGVIYDIALWMVPFG----------------------LI MAV_3172|M.avium_104 DRRWEARGG-ERGVIYDIALWTVPFG----------------------LV Mflv_3597|M.gilvum_PYR-GCK DRRWVARGG-EPGVIYDIALWAVPFG----------------------LI Mvan_2819|M.vanbaalenii_PYR-1 DRRWVARGG-ESGVIYDIALWAVPFG----------------------LI MAB_2642c|M.abscessus_ATCC_199 DRRWEQRGG-ERGVIYDIALWAVPFG----------------------LV TH_1073|M.thermoresistible__bu DRRWAARGG-ERGVIYDIALWAVPFG----------------------LI MSMEG_3222|M.smegmatis_MC2_155 DRRWQARGG-EPGVIYDIALWAVPFG----------------------LA MUL_2033|M.ulcerans_Agy99 QGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALPIEYTEVSI *** .: : : .*:* Mb1640|M.bovis_AF2122/97 GGRLYHLATDWRTYFGDGGAGLAAALRIWDGGLGIWGAVTLG-------- Rv1614|M.tuberculosis_H37Rv GGRLYHLATDWRTYFGDGGAGLAAALRIWDGGLGIWGAVTLG-------- MLBr_01274|M.leprae_Br4923 GGRLYHLATDWRTYFGQNGAGLGAALRIWDGGLGIWGAVALG-------- MMAR_2416|M.marinum_M GGRLYHLSTDWQTYFGEGGAGLGAALRIWDGGLGIWGAVTLG-------- MAV_3172|M.avium_104 GGRLYHLATDWRTYWGPGGAGFGAAVRIWDGGLGIWGAVALG-------- Mflv_3597|M.gilvum_PYR-GCK GGRLYHVITDWPTYFGDGGAGPAAALRIWDGGLGIWGAVALG-------- Mvan_2819|M.vanbaalenii_PYR-1 GGRLYHVITDWPTYFGEGGAGPAAALRIWDGGLGIWGAVALG-------- MAB_2642c|M.abscessus_ATCC_199 GGRLYHVMTDWQTYFGAHGKGIGKAIAVWEGGLGIWGAVALG-------- TH_1073|M.thermoresistible__bu GGRVYHVLTDWRTYFGPDGAGFVAALRIWDGGLGIWGAVALG-------- MSMEG_3222|M.smegmatis_MC2_155 GGRIYHVITDWKTYFGPTGKGFGAALQIWEGGLGIWGAVAFG-------- MUL_2033|M.ulcerans_Agy99 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDEIL *::: :. * : :.*:* * .* Mb1640|M.bovis_AF2122/97 -------------VMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGN Rv1614|M.tuberculosis_H37Rv -------------VMGAWIGCRRCGIPLPVLLDAVAPGVVLAQAIGRLGN MLBr_01274|M.leprae_Br4923 -------------CVGAWLGCRRHRIPLPAFGDALAPGIILAQAIGRLGN MMAR_2416|M.marinum_M -------------TVGAWIGCRRRGIPLPAFLDAVAPGVVMGQAIGRLGN MAV_3172|M.avium_104 -------------AVGAWIGCRRHGIPLPAFADALAPGIILAQAIGRLGN Mflv_3597|M.gilvum_PYR-GCK -------------AVGAWIACRRRGIPLPAFGDAIAPGIVLAQAIGRLGN Mvan_2819|M.vanbaalenii_PYR-1 -------------GIGAWIACRRRGIPLPAFGDAIAPGIVLAQAIGRLGN MAB_2642c|M.abscessus_ATCC_199 -------------GVGAWIACRRRGIPLPAFADAIAPGIVLAQAIGRLGN TH_1073|M.thermoresistible__bu -------------GVGAWIACRRHGIPLPAFGDAIAPGIVLAQAIGRLGN MSMEG_3222|M.smegmatis_MC2_155 -------------AVGAWIACRLRGIPLPAFGDAIAPGIILAQGIGRLGN MUL_2033|M.ulcerans_Agy99 QSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLTDLTTELRR *. : .* : * : : .* . Mb1640|M.bovis_AF2122/97 YFN--------------------------------------QELYGRETT Rv1614|M.tuberculosis_H37Rv YFN--------------------------------------QELYGRETT MLBr_01274|M.leprae_Br4923 YFN--------------------------------------QELYGRETT MMAR_2416|M.marinum_M YFN--------------------------------------QELYGRETT MAV_3172|M.avium_104 YFN--------------------------------------QELYGRETT Mflv_3597|M.gilvum_PYR-GCK YFN--------------------------------------QELYGRETT Mvan_2819|M.vanbaalenii_PYR-1 YFN--------------------------------------QELFGRETT MAB_2642c|M.abscessus_ATCC_199 YFN--------------------------------------QELTGGPTT TH_1073|M.thermoresistible__bu YFN--------------------------------------QELYGRPTT MSMEG_3222|M.smegmatis_MC2_155 YFN--------------------------------------QELYGRPTD MUL_2033|M.ulcerans_Agy99 QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAEREAIFEAEAT :: : : : Mb1640|M.bovis_AF2122/97 MP--------------------------------------WGLEIFYRRD Rv1614|M.tuberculosis_H37Rv MP--------------------------------------WGLEIFYRRD MLBr_01274|M.leprae_Br4923 MP--------------------------------------WGLEVFYRRD MMAR_2416|M.marinum_M VP--------------------------------------WGLEIFYRRD MAV_3172|M.avium_104 LP--------------------------------------WGLEIFYRRD Mflv_3597|M.gilvum_PYR-GCK VP--------------------------------------WGLEIYERRN Mvan_2819|M.vanbaalenii_PYR-1 VP--------------------------------------WGLEIYERVN MAB_2642c|M.abscessus_ATCC_199 LP--------------------------------------WGLELFYRRS TH_1073|M.thermoresistible__bu LP--------------------------------------WGLEIYERRN MSMEG_3222|M.smegmatis_MC2_155 VP--------------------------------------WGLEIYERLN MUL_2033|M.ulcerans_Agy99 MRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWFGLSALAERV : :**. . Mb1640|M.bovis_AF2122/97 ---------PSGFDVPNSLDGVSTG--------QVAFVVQPTFLYELIWN Rv1614|M.tuberculosis_H37Rv ---------PSGFDVPNSLDGVSTG--------QVAFVVQPTFLYELIWN MLBr_01274|M.leprae_Br4923 ---------PAGYMDPHSLDGVSTG--------QLAFVVQPTFLYELIWN MMAR_2416|M.marinum_M ---------PSGFVDVHSLDGVSTG--------QVAVVVQPTFLYELIWN MAV_3172|M.avium_104 ---------PSGYIDPHSLDGVSTG--------QVALVVQPTFLYELLWN Mflv_3597|M.gilvum_PYR-GCK ---------SAGVLDSLN--GISTG--------ELIGVVHPTFLYELLWN Mvan_2819|M.vanbaalenii_PYR-1 ---------AAGVPDSLN--GVSTG--------ELIQVVHPTFLYELLWN MAB_2642c|M.abscessus_ATCC_199 ---------ADGTVDVLNLNGVSTG--------EVAQVVHPTFLYELLWN TH_1073|M.thermoresistible__bu ---------ASGALDPLN--GTSTG--------ELLAVVHPTFLYEMLWN MSMEG_3222|M.smegmatis_MC2_155 ---------KFGQSDQLN--GVSTG--------QVTAVVHPTFLYELIWN MUL_2033|M.ulcerans_Agy99 GTTVRIANERAQHLDVEPVTNSDTDPDALDAEAEQVAIAEQQLLVELAEA . .*. : :.. :* *: Mb1640|M.bovis_AF2122/97 -----------------------VLVFVALIYIDRR-------------- Rv1614|M.tuberculosis_H37Rv -----------------------VLVFVALIYIDRR-------------- MLBr_01274|M.leprae_Br4923 -----------------------VLVFFALIYVDRW-------------- MMAR_2416|M.marinum_M -----------------------LLVFAALIYLDRR-------------- MAV_3172|M.avium_104 -----------------------LLIFVALLYADRR-------------- Mflv_3597|M.gilvum_PYR-GCK -----------------------LLVFAVLILVDRR-------------- Mvan_2819|M.vanbaalenii_PYR-1 -----------------------LLVFAVLILVDRR-------------- MAB_2642c|M.abscessus_ATCC_199 -----------------------VLVFVLLIVVDRR-------------- TH_1073|M.thermoresistible__bu -----------------------VLVFVVLIWADRR-------------- MSMEG_3222|M.smegmatis_MC2_155 -----------------------IAVFGFLIWVDRK-------------- MUL_2033|M.ulcerans_Agy99 RDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLARLAGQVETMR : ** Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2819|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2033|M.ulcerans_Agy99 ARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGELDQGEVGLDE Mb1640|M.bovis_AF2122/97 --------FIIGHGRLFGFYVAF-----------YCAGRFCVELLRDDPA Rv1614|M.tuberculosis_H37Rv --------FIIGHGRLFGFYVAF-----------YCAGRFCVELLRDDPA MLBr_01274|M.leprae_Br4923 --------FTLGHGRLFATYVAA-----------YCIGRFCVELLRDDAA MMAR_2416|M.marinum_M --------FTIGHGRLFASYVAL-----------YCVGRFCVELLRDDTA MAV_3172|M.avium_104 --------LTLGHGRLFALYVAG-----------YCVGRFCVELLRDDTA Mflv_3597|M.gilvum_PYR-GCK --------FKIGHGRLFALYVAG-----------YCAGRFWIELMRSDTA Mvan_2819|M.vanbaalenii_PYR-1 --------FKIGHGRLFALYVAG-----------YCVGRFWIELMRSDTA MAB_2642c|M.abscessus_ATCC_199 --------FKIGHGRLFAMYVAA-----------YCVGRFCVELMRVDPA TH_1073|M.thermoresistible__bu --------FRLGHGRLFALYVAG-----------YCVGRFWVELLRSDFA MSMEG_3222|M.smegmatis_MC2_155 --------FRIGHGRLFALYVAS-----------YCVGRFWVELMRSDTA MUL_2033|M.ulcerans_Agy99 QHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALSVGLDRKDGA : :.. ** ** * : : * * * * Mb1640|M.bovis_AF2122/97 TLIAG--------------------------------------------- Rv1614|M.tuberculosis_H37Rv TLIAG--------------------------------------------- MLBr_01274|M.leprae_Br4923 THIAG--------------------------------------------- MMAR_2416|M.marinum_M THIAG--------------------------------------------- MAV_3172|M.avium_104 THIAG--------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK TLLAG--------------------------------------------- Mvan_2819|M.vanbaalenii_PYR-1 TLLAG--------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 TQFGG--------------------------------------------- TH_1073|M.thermoresistible__bu THIAG--------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 TEFAG--------------------------------------------- MUL_2033|M.ulcerans_Agy99 AWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEALAADSFGAAR : :. Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2819|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2033|M.ulcerans_Agy99 SAVTALKQADGGRAALVLGDWPDAHDHRAAGGLPSGTLWALDLIEVPSRL Mb1640|M.bovis_AF2122/97 -----------IRINSFTSTFVFIGAVVYIILAPKGREAPGA--LRGSEY Rv1614|M.tuberculosis_H37Rv -----------IRINSFTSTFVFIGAVVYIILAPKGREAPGA--LRGSEY MLBr_01274|M.leprae_Br4923 -----------IRINSFTSTFVFIGAVVYIILAPKGREEPEN--LCRAEY MMAR_2416|M.marinum_M -----------IRINSFTSTFVFIGAVVYIILAPKGREDPAS--VRGTAA MAV_3172|M.avium_104 -----------IRINSFTSTFVFIGAVVYLMAAPKGREDPES--LRGNQY Mflv_3597|M.gilvum_PYR-GCK -----------IRVNTFTATFVFVAAVVYVIVAPKGREAPES--LRGNQD Mvan_2819|M.vanbaalenii_PYR-1 -----------IRVNSFTSTFVFIGAVVYIMAAPKGREDPSS--LKGNQD MAB_2642c|M.abscessus_ATCC_199 -----------IRVNSFTSTLVFVGAVAYILLAPKGREDPAT--LGGTPS TH_1073|M.thermoresistible__bu -----------IRINSFTASFVFIGAVVYIMVAPKGREDPAT--LGGPVQ MSMEG_3222|M.smegmatis_MC2_155 -----------IRVNTFTSTFVFIGAVVYIMLAPKGREEPES--LRGKAA MUL_2033|M.ulcerans_Agy99 RPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVGAGWVSGGSD : :* :: :: :: * : .. . : : Mb1640|M.bovis_AF2122/97 VVDEALEREPAELAAAAVASAASAVG--PVGP-----GEPNQPDDVAEAV Rv1614|M.tuberculosis_H37Rv VVDEALEREPAELAAAAVASAASAVG--PVGP-----GEPNQPDDVAEAV MLBr_01274|M.leprae_Br4923 VAREIPEPESATERATVAS---------------------------TYAT MMAR_2416|M.marinum_M AAEEVPEPEPAGEVATAAAPAGDTEGDEPTGL-----AETAKAAEVAEPE MAV_3172|M.avium_104 VEEEPAEPEPATVAATTEA---------------------------ATEG Mflv_3597|M.gilvum_PYR-GCK AESDVEDLAKDVALASAVGVVAAATVAGEDEKRD-GGGSPPGGLGSVEGD Mvan_2819|M.vanbaalenii_PYR-1 AEARVEDLAKDVAVGSATGIVAAATVADEDE------AMEPADDDDAAEV MAB_2642c|M.abscessus_ATCC_199 SADGGDDTAETEAT---------------------------ADTEDTEDT TH_1073|M.thermoresistible__bu TDAGADTGAAGADAEVDTEVDTE--------------------KEDVAAA MSMEG_3222|M.smegmatis_MC2_155 DETEEGDEESLVDEAGKELVAAAAGTGVVAAATA-AAREDTDDTDGTTDP MUL_2033|M.ulcerans_Agy99 RKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQTARQDAAEQA . Mb1640|M.bovis_AF2122/97 KAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGD----- Rv1614|M.tuberculosis_H37Rv KAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGD----- MLBr_01274|M.leprae_Br4923 TTAVPVSADEEFAETN---------------------------------- MMAR_2416|M.marinum_M TVGSAVAGDESTADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAE MAV_3172|M.avium_104 VAAPADGAEAAGADATAQRPEESAEPDVEKPESEETEAEAAEEPE----- Mflv_3597|M.gilvum_PYR-GCK EALEAAGGASAANESAVEGAADAADLVALLEASEDVEVADGAVEPQEVDA Mvan_2819|M.vanbaalenii_PYR-1 EALVAELEASEP-ETEGLGSVEGDEVAEAVEVAP--EVHEAAVEG-EAEA MAB_2642c|M.abscessus_ATCC_199 EDGVTDAPEADATDKSVDESADNSGIVEK--------------------- TH_1073|M.thermoresistible__bu VRGVAGAGAXXXRHIARRRGRRRGERIRRRRRRQLVDRRRVQWLR----- MSMEG_3222|M.smegmatis_MC2_155 AAASDEPGDEAEPETEAATAVLTADGAEAMSVDEQPDDDEAVDEEAG--- MUL_2033|M.ulcerans_Agy99 LAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREELEVGRTQTL Mb1640|M.bovis_AF2122/97 ------------LAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEP-- Rv1614|M.tuberculosis_H37Rv ------------LAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEP-- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M AVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAEEAEEAEEAEEAEEAEE MAV_3172|M.avium_104 --------------SEETEAAEEPGEPEAEEPEEPEAEEPEEPETEEP-- Mflv_3597|M.gilvum_PYR-GCK PPVPDEAGGLGAVEGEEAAEAAAGAGAARASVSDDAEASNDADAETEAAG Mvan_2819|M.vanbaalenii_PYR-1 EELASDVEGAPEPEGVEAAEAEAESPVDGAEAESEVVEG-DVESVTESEG MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -----------RGIVHHIARGRAGQHLAAGRPRPLALAGQHPLGDRDLLL MSMEG_3222|M.smegmatis_MC2_155 -----------QEAEEPADELVELADEPEGEPEPAAAEEAEPAETIEPDE MUL_2033|M.ulcerans_Agy99 EEVLELESRLRNAQESQHVQAAEPVDRQEIAAAAESARAIEVEARLTVRT Mb1640|M.bovis_AF2122/97 ----------------------------------EVPEKAAPIP------ Rv1614|M.tuberculosis_H37Rv ----------------------------------EVPEKAAPIP------ MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M AEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAA MAV_3172|M.avium_104 ----------------------------------EADSDEEPEE------ Mflv_3597|M.gilvum_PYR-GCK LG---SVDGDEVAAAVEDAPEVHEAAVEGEAEAEELAAEAEVEAVAAEVA Mvan_2819|M.vanbaalenii_PYR-1 LG---SVEGDEVAEAVEVAPEVHEVVVEGEAEAEALAADAEAEAEA---- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu LG-------------------------GQVGVRRELAAAVGPPGAG---- MSMEG_3222|M.smegmatis_MC2_155 DEIFDAELAEALAEAAEDFAVVPESAGSDEAEVAAAESAADAEDGP---- MUL_2033|M.ulcerans_Agy99 AEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAAVAAAVAESG Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M EAVEGEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGGQT MAV_3172|M.avium_104 -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK EVDADALTGADDDVDAETEAAVEGEAEAEELAAEADAEAQVAAE-VAEVD Mvan_2819|M.vanbaalenii_PYR-1 EAEAEDLA-ADVEAESPVDGAED-ESEAESEVVEGDVESVTESEGLGSVE MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2033|M.ulcerans_Agy99 RLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSSLSARVATLT Mb1640|M.bovis_AF2122/97 ---------------------------------DPAKPDELAVAG----- Rv1614|M.tuberculosis_H37Rv ---------------------------------DPAKPDELAVAG----- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M GVDDAGEADAEPDDDSTAAEPEVVVEQADIEEIEPQEPEAEAVAAAEATD MAV_3172|M.avium_104 ---------------------------------ESGEAPEQPVAE----- Mflv_3597|M.gilvum_PYR-GCK ADALTGADDDVDAETEAEVEGEAEAEELAAEAD-AEAQVAAEVAEVDAET Mvan_2819|M.vanbaalenii_PYR-1 GDEVAEAVEVAPEVHEAAVEGEAEAEELASDVEGAPEPEGVEAAEAEAES MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu ---------------------------------SELQAPVIAVTGVDG-- MSMEG_3222|M.smegmatis_MC2_155 ------------------------------SDAESAEVPAEAAADDAVVS MUL_2033|M.ulcerans_Agy99 DSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGPDVALPPTEL Mb1640|M.bovis_AF2122/97 --------------------------------------------PGDDPA Rv1614|M.tuberculosis_H37Rv --------------------------------------------PGDDPA MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M ADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAEESGDESPEPAADSE MAV_3172|M.avium_104 -------------------------------------------EPEPAPQ Mflv_3597|M.gilvum_PYR-GCK -LTGADKDVDAEALT-DADAETEAAGLGSVDGDEVAAAVEDAPEVHEAAV Mvan_2819|M.vanbaalenii_PYR-1 PVDGAEAEAESEVVEGDVESVTESEGLGSVEGDEVAEAVEVAPEVHEVVV MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------PVSARLA MSMEG_3222|M.smegmatis_MC2_155 EPAG-------------------------------------TVDETEVAE MUL_2033|M.ulcerans_Agy99 EMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTELGRVNPLAL Mb1640|M.bovis_AF2122/97 EPDG----------------------------IRRQDDFSS--------- Rv1614|M.tuberculosis_H37Rv EPDG----------------------------IRRQDDFSS--------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M EPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGSDQTSAGDGEGPPP MAV_3172|M.avium_104 QPET---------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK EGESEAEELAAEADAEALAEVAEIDAEAVNDADED--------------V Mvan_2819|M.vanbaalenii_PYR-1 EGEAEAEALAADADADADAEAEDLAADVEAESPVDGAEDESEAEPEAVEG MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu TGDLIPFG------------------------------------------ MSMEG_3222|M.smegmatis_MC2_155 EAAAEAADLEFESYDAELAEALAEAAEDMAVVVAPAETAESDEAREPVET MUL_2033|M.ulcerans_Agy99 EEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQVFSDAFVDVE Mb1640|M.bovis_AF2122/97 ---------RRRRWWRLRRRRQ---------------------------- Rv1614|M.tuberculosis_H37Rv ---------RRRRWWRLRRRRQ---------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M SAAVDGDTGPTRQGWRGRLRNRMRRSGR---------------------- MAV_3172|M.avium_104 -----------KRRWGARLRDRLSGR------------------------ Mflv_3597|M.gilvum_PYR-GCK DAEAEAEAAGLGSVDGDEVAAAVEDAPEVREAVEG---------VAEVDA Mvan_2819|M.vanbaalenii_PYR-1 DVESVTESEGLGSVEGDEAAEAEELVGEVEADVEAETGEAAADEVAEVDA MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------VGGRTGLTGHRQAATAEHSPGDSDFRDVYG------------- MSMEG_3222|M.smegmatis_MC2_155 DATESEEPSEPEEPDAPEAVEAPEALDENADETRAEPAAPAAVATAPVEP MUL_2033|M.ulcerans_Agy99 REFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKKVSRLSLLSG Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK EALTDAE----------------------------------PEESDAEGE Mvan_2819|M.vanbaalenii_PYR-1 GAVTDTDDDAEGLGSVEGDEVAESAEDASEVHEAAVEREEAAEERAAEAE MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 E------------------------------------------------- MUL_2033|M.ulcerans_Agy99 GEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLIGLFEMLRDR Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK PEGPALP------TSEHSPYTVVT--ESSSEPAQSGPAGLVRQWIRRRRN Mvan_2819|M.vanbaalenii_PYR-1 ADDASEPQPEEAADTEPAADGAVTRVESRSVATESQSGGLLRRMLRRRRS MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------KGRLRRWLRRNR- MUL_2033|M.ulcerans_Agy99 SQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQVDRLVANSS Mb1640|M.bovis_AF2122/97 - Rv1614|M.tuberculosis_H37Rv - MLBr_01274|M.leprae_Br4923 - MMAR_2416|M.marinum_M - MAV_3172|M.avium_104 - Mflv_3597|M.gilvum_PYR-GCK R Mvan_2819|M.vanbaalenii_PYR-1 R MAB_2642c|M.abscessus_ATCC_199 - TH_1073|M.thermoresistible__bu - MSMEG_3222|M.smegmatis_MC2_155 - MUL_2033|M.ulcerans_Agy99 -