For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VERTAVGPTLIVAIDQYDERTLVPDPWAVRILPRRWRVPAVLSRFKVVRNAMIAATENSVRGGWASLLCR KRYIDDVLAGAASGGGLDAVVILGAGYDTRAHRVLQLSDVPVWEVDLPDNIAAKTAALQRCFGPMPANVT PVSVDLEHGDLIGSLTGAGFDTGMRTAFVWESVTMYLTEPVVRRTLQATSACAAGSHLVFTHFRKDFVDG VSLYGAQKARERFADKLHLWRYGIDPEDVAGVLAEYGWRETEQAGASEYRKRYLAPAGRSDPLSEIERAV WAQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1501 | - | - | 100% (284) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_3424 | - | 2e-15 | 31.10% (283) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_1481 | - | 2e-15 | 29.37% (269) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2772 | - | 8e-66 | 47.18% (284) | hypothetical protein Mb2772 |
| M. gilvum PYR-GCK | Mflv_3997 | - | 1e-56 | 42.76% (283) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv2751 | - | 8e-66 | 47.18% (284) | hypothetical protein Rv2751 |
| M. leprae Br4923 | MLBr_02640 | - | 5e-09 | 25.43% (291) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3082 | - | 3e-59 | 43.01% (286) | hypothetical protein MAB_3082 |
| M. marinum M | MMAR_1964 | - | 8e-59 | 44.06% (286) | O-methyltransferase |
| M. avium 104 | MAV_3642 | - | 3e-57 | 43.37% (279) | methyltransferase, putative, family protein |
| M. thermoresistible (build 8) | TH_0301 | - | 2e-16 | 32.74% (223) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3393 | - | 7e-59 | 44.06% (286) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2390 | - | 3e-61 | 45.07% (284) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2772|M.bovis_AF2122/97 ------MARNPAAQTAFGPMVLAAVEQNEPPGRRLVDDDLADLFLP----
Rv2751|M.tuberculosis_H37Rv ------MARNPAAQTAFGPMVLAAVEQNEPPGRRLVDDDLADLFLP----
MMAR_1964|M.marinum_M ------MTRNPAAQTAFGPMVLSAVEQNEPAEHRLVDDDLADLFLP----
MUL_3393|M.ulcerans_Agy99 ------MTRNPAAQTAFGPMVLSAVEQNEPAEHRLVDDDLADLFLP----
MAV_3642|M.avium_104 -------------------MVLAAVEQNEPPGRRLVDDDFAELFLP----
Mflv_3997|M.gilvum_PYR-GCK -----MTSRDAAAETAFGPMVLAAIEHNEPPDRRLVDDDLAESFLP----
Mvan_2390|M.vanbaalenii_PYR-1 -----MTARDAAAQTAFGPMVLAAIEQNEPPLQRLVHDDLAESFLP----
MAB_3082|M.abscessus_ATCC_1997 -----MPQSNPAAQTAFGPMAITAVEQHEPAAARIVDDDLAAHILP----
MSMEG_1501|M.smegmatis_MC2_155 -----------MERTAVGPTLIVAIDQYD--ERTLVPDPWAVRILP----
MLBr_02640|M.leprae_Br4923 MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTGA
TH_0301|M.thermoresistible__bu ----------------------MXGGASRD-PKELINDPFAAPLVRAVGI
:: * * ::
Mb2772|M.bovis_AF2122/97 RPLRWLAGATRSAVLRRLLISASEWSGRGLWANLACRKRFIGDKLD--EA
Rv2751|M.tuberculosis_H37Rv RPLRWLAGATRSAVLRRLLISASEWSGRGLWANLACRKRFIGDKLD--EA
MMAR_1964|M.marinum_M RPLRWLVSATRPAGIRRLFIRWSEWSGSGLWVNLTCRKRFIGDKLG--EA
MUL_3393|M.ulcerans_Agy99 RPLRWLVSATRPAGIRRLFIRWSEWSGSGLWVNLTCRKRFIGDRLG--EA
MAV_3642|M.avium_104 APLRWLVGATRFAPVRHLMIRGSEFTGPGLWANLACRKRFIADKLK--ES
Mflv_3997|M.gilvum_PYR-GCK NRFRLLVRCARVAAVRRAVIAAADRSGPGLWASIACRKRYIDERLS--DP
Mvan_2390|M.vanbaalenii_PYR-1 GRLRLLVRLTRVAALRRAAATVTDRSGPGLWASIACRKRYIDERLS--DP
MAB_3082|M.abscessus_ATCC_1997 RGLRWFVRATAWAPLRHWLIRLTERGGQGAWSLFVCRKRYIDDQLA--AS
MSMEG_1501|M.smegmatis_MC2_155 RRWRVPAVLSRFKVVRNAMIAATENSVRGGWASLLCRKRYIDDVLAGAAS
MLBr_02640|M.leprae_Br4923 GALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFN-NAV
TH_0301|M.thermoresistible__bu -DFFTRIADGELT--VADLDPQSAPRVQANIDEVAVRTRFFDDHFA-AAT
: *..:: :
Mb2772|M.bovis_AF2122/97 LGDIDAVVILGAGLDTRAYRLTRRVRMPVFEVDLPVNIARKAKTVRRVLG
Rv2751|M.tuberculosis_H37Rv LGDIDAVVILGAGLDTRAYRLTRRVRMPVFEVDLPVNIARKAKTVRRVLG
MMAR_1964|M.marinum_M LDDIDAVAILGAGLDTRAYRLTRKVRIPIFEVDLPVNIARKAKTVRRVLG
MUL_3393|M.ulcerans_Agy99 LDDVDAVAILGAGLDTRAYRLTRKMRIPIFEVDLPVNIARKAKTVRRVLG
MAV_3642|M.avium_104 LDDINAVVILGAGLDTRAYLLTRRVRIPVFEVDLPVNVARKFKTVRRVLG
Mflv_3997|M.gilvum_PYR-GCK LNDTDAVVVLGAGLDTRSCRIARHSTMPVFEVDQQINVDRKQAVLRRTLG
Mvan_2390|M.vanbaalenii_PYR-1 LNDTDAVVVLGAGLDTRACRIARHGDLPVFEVDRPVNVDRKAAVLHRVFG
MAB_3082|M.abscessus_ATCC_1997 S--IDAVVDLGAGLDTRGCRVARAAPTPVFEVDQAVNIAIKQQAVKRALG
MSMEG_1501|M.smegmatis_MC2_155 GGGLDAVVILGAGYDTRAHRVLQLSDVPVWEVDLPDNIAAKTAALQRCFG
MLBr_02640|M.leprae_Br4923 IDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGV
TH_0301|M.thermoresistible__bu ARGIRQAVILAAGLDARAYRLRWPDGTVVYEIDQPRVIEFKTRTLARLGA
. *.:* *:*. : ::*:* : * .: .
Mb2772|M.bovis_AF2122/97 ELPLSVRLVALDFEHDDLLTALAEHGYRTEYRVFFVCEGVTQYLTERAVR
Rv2751|M.tuberculosis_H37Rv ELPLSVRLVALDFEHDDLLTALAEHGYRTEYRVFFVCEGVTQYLTERAVR
MMAR_1964|M.marinum_M ELPLSVRLVALDFEHDDLLTALAEHGYLTDFRVFFICEGVTQYLTEETVR
MUL_3393|M.ulcerans_Agy99 ELPLSVRLVALDFEHDDLLTALAEHGYLTDFRVFFICEDVTQYLTEETVR
MAV_3642|M.avium_104 ELPLSVRLVALDLEHDDLLTALAEHGYRTDYRVFFICEGVTQYLSEATVR
Mflv_3997|M.gilvum_PYR-GCK EVPSSVRLVGVDLERGQVMPALRAQGYDTRARTFFSRAPLTPF--PDAVR
Mvan_2390|M.vanbaalenii_PYR-1 AVPASVHLVPVDLEEDPLIPALESHGYRPEQRTFFIWEGVTQYLSPEAVH
MAB_3082|M.abscessus_ATCC_1997 AVPASLHLVPVDFQRDELAEELRRAGHDTAHRTFFIWEGVTQYIPETAVR
MSMEG_1501|M.smegmatis_MC2_155 PMPANVTPVSVDLEHGDLIGSLTGAGFDTGMRTAFVWESVTMYLTEPVVR
MLBr_02640|M.leprae_Br4923 TPTADRREVPIDLR-QDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQD
TH_0301|M.thermoresistible__bu EPTAERRTVAADLR-HDWPAALTAAGFDPAAPTVWIAEGLFGYLPPDAQD
. . * *:. * *. . . : : : .
Mb2772|M.bovis_AF2122/97 RTLEGLR-AAAPGSRMVFTYVRRDFIDGTNRYGTRT--------LYHTVR
Rv2751|M.tuberculosis_H37Rv RTLEGLR-AAAPGSRMVFTYVRRDFIDGTNRYGTRT--------LYHTVR
MMAR_1964|M.marinum_M RTLEGLR-AAAPGSRLVFTYVRRDFIDGTNRYGTRT--------LYRSVR
MUL_3393|M.ulcerans_Agy99 RTLEGLR-AAAPGSRLVFTYVRRDFIDGTNRYGTRT--------LYRSVR
MAV_3642|M.avium_104 RTLDGLR-AAAPGSRLVFTYVRSDFIDGTNRYGTRT--------LYRNVR
Mflv_3997|M.gilvum_PYR-GCK ATLTQLD-GAAEGSKLIFSYIRQDFIDGTDLYGARS--------VYRRFR
Mvan_2390|M.vanbaalenii_PYR-1 ATLAQLA-GAAPGSKLVFTYIRQDFIDGTNLYGADA--------VYRRFR
MAB_3082|M.abscessus_ATCC_1997 ATLAYLG-TAATGSRLAFTYVQRDFIDGSNLYGNSM--------LYKRFR
MSMEG_1501|M.smegmatis_MC2_155 RTLQATS-ACAAGSHLVFTHFRKDFVDGVSLYGAQK--------ARERFA
MLBr_02640|M.leprae_Br4923 GLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDAL-GFEQAV
TH_0301|M.thermoresistible__bu RLLDQITDLSAVGSRLGVEGVPAHADADEDEVRQRMRILAERWRAHGLDL
: .* **:: . . .
Mb2772|M.bovis_AF2122/97 QRRQLWHFGLDPEEVAGFLADYGWRLTEQAGPEELVQRYVEPTGRNLNAS
Rv2751|M.tuberculosis_H37Rv QRRQLWHFGLDPEEVAGFLADYGWRLTEQAGPEELVQRYVEPTGRNLNAS
MMAR_1964|M.marinum_M QRRQLWHFGLLPDEVPEFLAEYGWRLVEQAGPDELVQRYVEPAGRKLNAS
MUL_3393|M.ulcerans_Agy99 QRRQLWHFGLLPDEVPEFLAEYGWRLVEQAGPDELVQRYVEPAGRKLNAS
MAV_3642|M.avium_104 QRRQLWHFGLQPGEVADFLAEYGWRLVEQAGPDELMQRYVVPTGRKLKAS
Mflv_3997|M.gilvum_PYR-GCK QRRAVWKSGLVPEHVGELLADHGWRLVEQAGPSYYRDTYIRPTGRPLAAS
Mvan_2390|M.vanbaalenii_PYR-1 KRSQVWRSGVVPEQVGELLAGHGWRLVEQAGPSYFRDTYIRPTGREVSAS
MAB_3082|M.abscessus_ATCC_1997 VRSQVWMFGLTPGTVGPLLAEYGWQVLEDVSGPEYQRRYLIPAGRTLSTT
MSMEG_1501|M.smegmatis_MC2_155 DKLHLWRYGIDPEDVAGVLAEYGWRETEQAGASEYRKRYLAPAGRSDPLS
MLBr_02640|M.leprae_Br4923 DVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADD
TH_0301|M.thermoresistible__bu DFSELIYLG-DRADVAGYLADRGWRCTALTANELLVRTG-----LPPAEN
: . * * **: .
Mb2772|M.bovis_AF2122/97 QIEWSAYAEKSEPVTPR----
Rv2751|M.tuberculosis_H37Rv QIEWSAYAEKSEPVTPR----
MMAR_1964|M.marinum_M QIEWSAYAEKL----------
MUL_3393|M.ulcerans_Agy99 QIEWSAYAEKL----------
MAV_3642|M.avium_104 QLEWSAYAEKT----------
Mflv_3997|M.gilvum_PYR-GCK PLEWTVFAER-----------
Mvan_2390|M.vanbaalenii_PYR-1 PVEWTVLAER-----------
MAB_3082|M.abscessus_ATCC_1997 ELERTVLAEKI----------
MSMEG_1501|M.smegmatis_MC2_155 EIERAVWAQR-----------
MLBr_02640|M.leprae_Br4923 KDAFAEFVTAHRL--------
TH_0301|M.thermoresistible__bu DGRVTEVVYLSSEKSPGKRAG
: .