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SKLTPKYEELQSIYDISNEFYELFLGPTMGYTCGYFERDDMTGDEAQIAKFDLALGKLGLEPGMTLLDIG CGWGACMARAAEKYDVNVIGLTLSGEQREYAIEKLSKVPTDRKLEVRLQGWEEFDEKVDRIVSIGAFEHF GFERYPAFFDMAYNALPDDGVMLLHNITGFDLREGQKLGLHMTFEDARFARFIMTEIFPGGRLPSVVMEQ EKAIEAGFKLTQLQEIGPHYVRTLKIWADALEANKDEAIAIQGQEVYDRYDKYLNGCQKYFASGHISVHQ FTLQK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1350 | - | - | 100% (286) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. smegmatis MC2 155 | MSMEG_0913 | - | e-103 | 63.51% (285) | methoxy mycolic acid synthase 1 |
| M. smegmatis MC2 155 | MSMEG_1351 | - | 2e-97 | 60.21% (284) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3424c | cmaA1 | 4e-98 | 60.21% (284) | cyclopropane-fatty-acyl-phospholipid synthase 1 CMAA1 |
| M. gilvum PYR-GCK | Mflv_3304 | - | 1e-91 | 58.30% (283) | cyclopropane-fatty-acyl-phospholipid synthase |
| M. tuberculosis H37Rv | Rv3392c | cmaA1 | 5e-98 | 60.21% (284) | cyclopropane-fatty-acyl-phospholipid synthase 1 CMAA1 |
| M. leprae Br4923 | MLBr_02459 | umaA2 | 7e-93 | 57.75% (284) | Mycolic acid synthase |
| M. abscessus ATCC 19977 | MAB_4088c | - | 2e-94 | 59.86% (289) | mycolic acid synthase UmaA1 |
| M. marinum M | MMAR_0979 | mmaA5_1 | 1e-100 | 59.86% (284) | methoxy mycolic acid synthase 5 MmaA5_1 |
| M. avium 104 | MAV_4680 | - | 3e-99 | 62.59% (286) | methoxy mycolic acid synthase 1 |
| M. thermoresistible (build 8) | TH_3763 | - | 4e-96 | 60.70% (285) | PUTATIVE Cyclopropane-fatty-acyl-phospholipid synthase |
| M. ulcerans Agy99 | MUL_4538 | umaA | 2e-98 | 60.49% (286) | mycolic acid synthase UmaA |
| M. vanbaalenii PYR-1 | Mvan_0803 | - | 2e-97 | 61.84% (283) | cyclopropane-fatty-acyl-phospholipid synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4088c|M.abscessus_ATCC_199 ------MS----DLKPYYEESQSIYDISDEFYGLFLDEETMGYTCAYFER
Mvan_0803|M.vanbaalenii_PYR-1 ------MSNAVPDLSPYYEESQSIYDVSNEFFALFLG-PTMGYTCSYFER
MAV_4680|M.avium_104 ---MPRMT----GLEPYYEESQSIYDVSDEFFALFLD-PTMAYTCAFFER
MUL_4538|M.ulcerans_Agy99 ------MT----ELRPFYEESQSIYDVSDEFFALFLD-PTMAYTCAYFER
TH_3763|M.thermoresistible__bu ------MTNTSAELEPFFEESQSIYDVSDDFFALFLG-PTMGYTCAYFER
MSMEG_1350|M.smegmatis_MC2_155 ------MS----KLTPKYEELQSIYDISNEFYELFLG-PTMGYTCGYFER
Mb3424c|M.bovis_AF2122/97 ------MP---DELKPHFANVQAHYDLSDDFFRLFLD-PTQTYSCAYFER
Rv3392c|M.tuberculosis_H37Rv ------MP---DELKPHFANVQAHYDLSDDFFRLFLD-PTQTYSCAYFER
MMAR_0979|M.marinum_M ------MA---KELKPHFDDVQAHYDLSDDFFRLFLD-PTQTYSCAYFER
MLBr_02459|M.leprae_Br4923 ------MS---VQLTPHFRNVQAHYDLSDDFFRLFLD-PTLTYSCAYFER
Mflv_3304|M.gilvum_PYR-GCK MSDTPNGS---ADLQPHFDDVQSHYDLSDDFYRLFLD-PTQTYSCAYFER
. * * : : *: **:*::*: ***. * *:*.:***
MAB_4088c|M.abscessus_ATCC_199 DDLTLAEAQIAKFDLALGKLNLEPGMTVLDIGCGWGACLDRAMRKFDVNV
Mvan_0803|M.vanbaalenii_PYR-1 EDMTLDEAQIAKFDLALGKLNLEPGMTLLDVGCGWGGALRRAVEKYDVNV
MAV_4680|M.avium_104 DDMTLEEAQTAKFDLALGKLNLEPGMTLLDIGCGWGGALKRALEKYDVNV
MUL_4538|M.ulcerans_Agy99 DDMTLEEASNAKFDLALGKLNLEPGMTLLDIGCGWGGALQRAVEKYDVNV
TH_3763|M.thermoresistible__bu DDMTLDEAQIAKFDLALGKLNLEPGMTLLDIGCGWGGALQLALEKYDVNV
MSMEG_1350|M.smegmatis_MC2_155 DDMTGDEAQIAKFDLALGKLGLEPGMTLLDIGCGWGACMARAAEKYDVNV
Mb3424c|M.bovis_AF2122/97 DDMTLQEAQIAKIDLALGKLGLQPGMTLLDVGCGWGATMMRAVEKYDVNV
Rv3392c|M.tuberculosis_H37Rv DDMTLQEAQIAKIDLALGKLGLQPGMTLLDVGCGWGATMMRAVEKYDVNV
MMAR_0979|M.marinum_M DDMTLEEAQIAKIDLALGKLGLEPGMTLLDVGCGWGATMRRAIEKYDVNV
MLBr_02459|M.leprae_Br4923 DDMTLEEAQLAKVDLALGKLKLEPGMTLLDIGCGWGATMKRAIEIYDVNV
Mflv_3304|M.gilvum_PYR-GCK DDMTLEEAQRAKIDLALGKLGLEPGMTLLDIGCGWGGTLLRALEKYDVNV
:*:* **. **.******* *:****:**:*****. : * . :****
MAB_4088c|M.abscessus_ATCC_199 IGITLSKNQSEYSRKRLAQVAAETGRSAEIRMQGWEEFNDKVDRIVTIGA
Mvan_0803|M.vanbaalenii_PYR-1 IGITLSRKQFEYSKALMAG--LDTERKAEVRLQGWEEFDEPVDRIVSIGA
MAV_4680|M.avium_104 IGITLSRNQFEYSKKLLAG--FPTDRNIEVRLQGWEEFDDKVDRIVTIGA
MUL_4538|M.ulcerans_Agy99 IGITLSRNQFDYSKAKMAK--IPTERTVEVRLQGWEEFEDKVDRIVTIGA
TH_3763|M.thermoresistible__bu IGITLSRNQYEYSKARLAQ--IDTARTAEVRLQGWEQFDEPVDRIVSIGA
MSMEG_1350|M.smegmatis_MC2_155 IGLTLSGEQREYAIEKLSK--VPTDRKLEVRLQGWEEFDEKVDRIVSIGA
Mb3424c|M.bovis_AF2122/97 VGLTLSKNQANHVQQLVAN--SESLRSKRVLLAGWEQFDEPVDRIVSIGA
Rv3392c|M.tuberculosis_H37Rv VGLTLSKNQANHVQQLVAN--SENLRSKRVLLAGWEQFDEPVDRIVSIGA
MMAR_0979|M.marinum_M VGLTLSKNQAAHVQKSFDQ--LDTARTRRVLLEGWEQFDEPVDRIVSIGA
MLBr_02459|M.leprae_Br4923 IGLTLSENQAAHVQKTFDE--LDTPRTRRVLLEGWEKFHEPVDRIVSIGA
Mflv_3304|M.gilvum_PYR-GCK IGLTLSRNQQAHVQKVLDE--HDSPRSKTVLLQGWEQFDQPVDRIVSIGA
:*:*** :* : . . *. : : ***:*.: *****:***
MAB_4088c|M.abscessus_ATCC_199 FEAFKQERYPIFFERAYDILPNDGRMLLHTILAHTQQFFRENGIAITISD
Mvan_0803|M.vanbaalenii_PYR-1 FEAFKAERYPLFFERAYDILPADGRMLLHTILAHTQKFFRDNGIKLTISD
MAV_4680|M.avium_104 FEAFKMERYSAFFDRAYDILPDDGRMLLHTILTYTQKQQHERGVSITMSD
MUL_4538|M.ulcerans_Agy99 FEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQFHEMGVKVTMSD
TH_3763|M.thermoresistible__bu FEAFKKPRYAAFFEMAHKALPADGRMLLHTILAHPQTYFREAGIKITISD
MSMEG_1350|M.smegmatis_MC2_155 FEHFGFERYPAFFDMAYNALPDDGVMLLHNITGFDLREGQKLGLHMTFED
Mb3424c|M.bovis_AF2122/97 FEHFGHERYDAFFSLAHRLLPADGVMLLHTITGLHPKEIHERGLPMSFTF
Rv3392c|M.tuberculosis_H37Rv FEHFGHERYDAFFSLAHRLLPADGVMLLHTITGLHPKEIHERGLPMSFTF
MMAR_0979|M.marinum_M FEHFGHDRYDDFFTLAHNILPSDGVMLLHTITGLTFQQATDRGMPLTFEI
MLBr_02459|M.leprae_Br4923 FEHFGRQRYARFFKMAHEVLPADSVMLLHTIVRPTFKDARARGMTLTHEI
Mflv_3304|M.gilvum_PYR-GCK FEHFGSDRYDEFFRRAYSVLPDDGVMLLHTIVKPSDEEFAERKLPLTMTK
** * ** ** :: ** *. ****.* : ::
MAB_4088c|M.abscessus_ATCC_199 LKFMKFIGEEIFPGGQLPAVEDIEKLAADSGFNLERVHLLQPHYAKTLDI
Mvan_0803|M.vanbaalenii_PYR-1 LKFMRFIGTEIFPGGQLPAVEDIEKLAADSGFTLERAHLLRPHYARTLDM
MAV_4680|M.avium_104 LRFMRFIGQEIFPGGQLPAQEDIFKFGEAAGFSVERVQLLREHYARTLNI
MUL_4538|M.ulcerans_Agy99 VRFMRFIGQEIFPGGQLPAQEDIFNFAQAAGFSVERAQLLQQHYARTLNI
TH_3763|M.thermoresistible__bu LKFMQFIGREIFPGGELPAEGDVVEFATGAGFSVERIQLLRPHYARTLDI
MSMEG_1350|M.smegmatis_MC2_155 ARFARFIMTEIFPGGRLPSVVMEQEKAIEAGFKLTQLQEIGPHYVRTLKI
Mb3424c|M.bovis_AF2122/97 ARFLKFIVTEIFPGGRLPSIPMVQECASANGFTVTRVQSLQPHYAKTLDL
Rv3392c|M.tuberculosis_H37Rv ARFLKFIVTEIFPGGRLPSIPMVQECASANGFTVTRVQSLQPHYAKTLDL
MMAR_0979|M.marinum_M ARFIKFIVTEIFPGGRLPSIEKVADHSSKAGFTLTRRQSLQPHYARTLDL
MLBr_02459|M.leprae_Br4923 VHFTQFILAEIFPGGWLPTVPTVEEHATAAGFKFTRIQSLQLHYAKTLDL
Mflv_3304|M.gilvum_PYR-GCK LKFFKFIMDEIFPGGMLPKVDDVEKHATKASFKVNRIQPLRLHYARTLQI
:* :** ****** ** . . .*.. : : : **.:**.:
MAB_4088c|M.abscessus_ATCC_199 WAQNLEQRREEAIAIQSQEVYDRFMKYLTGCADFFRRGVTNVGQFTLVK-
Mvan_0803|M.vanbaalenii_PYR-1 WAANLEANRQEATRITSPEVYERYMHYLTGCADFFRRGITNVGQFTLVKG
MAV_4680|M.avium_104 WAANLEANKDKAIAIQSQAVYDRYMHYLTGCENFFRKGISNVGQFTLVK-
MUL_4538|M.ulcerans_Agy99 WAANLEARKEEAIAMQSQEIYDKYMHYLTGCENFFRKGISNVGQFTLVK-
TH_3763|M.thermoresistible__bu WAENLAANREPAIAMQSEEVYDRYYRYLTGCADFFRRGITNVGQFTLTKG
MSMEG_1350|M.smegmatis_MC2_155 WADALEANKDEAIAIQGQEVYDRYDKYLNGCQKYFASGHISVHQFTLQK-
Mb3424c|M.bovis_AF2122/97 WSAALQANKGQAIALQSEEVYERYMKYLTGCAEMFRIGYIDVNQFTCQK-
Rv3392c|M.tuberculosis_H37Rv WSAALQANKGQAIALQSEEVYERYMKYLTGCAEMFRIGYIDVNQFTCQK-
MMAR_0979|M.marinum_M WAQALQARRDEAIEVQSEEVYERYMKYLTGCADGFRVGYIDVNQFTLEKS
MLBr_02459|M.leprae_Br4923 WAARLEANKNKAIAIQSEEVYDRYMKYLTGCAKLFRDGYTDVDQFTLEKQ
Mflv_3304|M.gilvum_PYR-GCK WAASLESRRDDAIAIQSEEVYDRYMKYLTGCAELFTEGYTDVCQFTLAK-
*: * .: * : . :*::: :**.** . * * .* *** *
MAB_4088c|M.abscessus_ATCC_199 -------
Mvan_0803|M.vanbaalenii_PYR-1 -------
MAV_4680|M.avium_104 -------
MUL_4538|M.ulcerans_Agy99 -------
TH_3763|M.thermoresistible__bu -------
MSMEG_1350|M.smegmatis_MC2_155 -------
Mb3424c|M.bovis_AF2122/97 -------
Rv3392c|M.tuberculosis_H37Rv -------
MMAR_0979|M.marinum_M -------
MLBr_02459|M.leprae_Br4923 PATARRH
Mflv_3304|M.gilvum_PYR-GCK -------