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M. smegmatis MC2 155 MSMEG_1181 (hutF)

annotation: N-formimino-L-glutamate deiminase
coordinates: 1242546 - 1243877
length: 443

MTSYFADHTWLGDEQVADNVLITVDGDTITAVQRDAARPADATHLKGVTLPGLANAHSHAFHRALRGRTH
RGGGSFWTWREDMYAVAECLTPDSYYALARATYAEMALAGITCVGEFHYLHHLPGGTRYDDPNAMGAALI
AAAHAAGIRITLLDTCYLTGGVGQELQGPQLRFGDGDTATWAERADKLAAAPHAKIGAAIHSVRAVPPDS
IAAVAEWAAQRDTPLHFHLSEQRAENDACLQAYGTTPTRLLAEHGALGANATAVHATHLTHTDITDLAGT
GTTVCITPTTERDLADGIGPARELADAGCALSVGSDSNAIVDIFEETRAVELDERLRSEKRGHWTAAQLL
TAATADGHRALGWSTAGRIAPGAAADLVTVSLDSVRLAGAEPETLLESVVFAAHAGDVRDVVVSGRQVVA
DGRHTMVDDVPAALHAAIKDTLA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1181hutF-100% (443)N-formimino-L-glutamate deiminase
M. smegmatis MC2 155MSMEG_1297-5e-2829.34% (426) hydroxydechloroatrazine ethylaminohydrolase
M. smegmatis MC2 155MSMEG_1298-8e-0926.32% (209) guanine deaminase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2927c-8e-2829.46% (404) hydroxydechloroatrazine ethylaminohydrolase
M. marinum MMMAR_2844-1e-2729.93% (431) metal-dependent hydrolase
M. avium 104-----
M. thermoresistible (build 8)TH_3859-1e-1224.24% (429) PUTATIVE -
M. ulcerans Agy99MUL_2914-1e-2629.23% (431) hydroxydechloroatrazine ethylaminohydrolase
M. vanbaalenii PYR-1Mvan_3150-4e-2830.22% (407) amidohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2844|M.marinum_M               MSTILLTLMLECRVPKLVIDRVSIATVDPKAAEFSEGHIIVEDDLIVAVG
MUL_2914|M.ulcerans_Agy99           --------MLECRVPKLVIDRISIATVDPKAAEFSEGHIIVEDDLIVAVG
MAB_2927c|M.abscessus_ATCC_199      ------------MNPITLIENVFAATVDKSRREIADARVVIEGGRIAAVL
Mvan_3150|M.vanbaalenii_PYR-1       ------------MTERQVLHGGTVLTGPQWRP--RPADLLIAGGRIEAVA
TH_3859|M.thermoresistible__bu      -----------------------VLAGDPLTAHVRAADLLIEDGRVTAIE
MSMEG_1181|M.smegmatis_MC2_155      -----------------MTSYFADHTWLGDEQVADNVLITVDGDTITAVQ
                                                             :            : : .. : *: 

MMAR_2844|M.marinum_M               ----DGPAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRG--YTQKGT
MUL_2914|M.ulcerans_Agy99           ----DGPAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRG--HTQKGT
MAB_2927c|M.abscessus_ATCC_199      TAGENNPWQELPGVERVDGSGCLLTPGLVNTHHHLYQWITRG--LAADHT
Mvan_3150|M.vanbaalenii_PYR-1       ----APGSLAGVDAATHDVTGRLVIPGLINAHTHSHTAPARG--AARAWT
TH_3859|M.thermoresistible__bu      S------DLAGVDAEIIDATGRWVLPGFVDTHRHLWQTTMRG--LTANWN
MSMEG_1181|M.smegmatis_MC2_155      R-----DAARPADATHLKG---VTLPGLANAHSHAFHRALRGRTHRGGGS
                                                ..   .       **: ::* *      **       .

MMAR_2844|M.marinum_M               LFQWLTEMYPVWGRLDA-ELEFAAASAGLAGLALTGCTTTMDHHYVFPHA
MUL_2914|M.ulcerans_Agy99           LFQWLTEMYPVWGRLDA-ELEFAAASAGLAGLALTGCTTTMDHHYVFPHA
MAB_2927c|M.abscessus_ATCC_199      LFQWLTALYPVWQGIDA-DSLHVAAQGALSWLALSGCTTTTDHHYVFPSD
Mvan_3150|M.vanbaalenii_PYR-1       LEDSLLNGGWMAAPRSE-ELTELAALLTATELIASGCTGAFDLIAQAGGP
TH_3859|M.thermoresistible__bu      LKDYFWCIRSHFAGLHDPDDVYGGQYAGGLDALVNGVTTTIDHSHITNSP
MSMEG_1181|M.smegmatis_MC2_155      FWTWREDMYAVAECLTP-DSYYALARATYAEMALAGITCVGEFHYLHHLP
                                    :                 :                * * . :        

MMAR_2844|M.marinum_M               GGDMLGAEIAAAKRIGVRFHPTRGSMD---------LGVASGGLPPEHTV
MUL_2914|M.ulcerans_Agy99           GGDMLGAEIVAAKRIGVRFHPTRGSMD---------LGVASGGLPPEHTV
MAB_2927c|M.abscessus_ATCC_199      AGDLLEAEIEAARQVGLRFDPTRGSMD---------LGRSAGGLPPDGLV
Mvan_3150|M.vanbaalenii_PYR-1       DPAGCHAAARGYARAGLRTVLAPMVADRTLHEAVPAIGACCGAPSTGKPG
TH_3859|M.thermoresistible__bu      --DHSDAAVRGLLDSGVRALWCYGFYP----------------SPQADPV
MSMEG_1181|M.smegmatis_MC2_155      GGTRYDDPNAMGAALIAAAHAAGIRIT------LLDTCYLTGGVGQELQG
                                                                                      

MMAR_2844|M.marinum_M               EDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGELMKQSALLA
MUL_2914|M.ulcerans_Agy99           EDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGELMKQSALLA
MAB_2927c|M.abscessus_ATCC_199      ESIDTALEASDAAIARWHDPAPGAMVRIGLAPCSPFSVSADLLRQSALLA
Mvan_3150|M.vanbaalenii_PYR-1       PSTADVLAACTAYVRNFPALQG---VMPALAPTIPGHCTPELTVGLGRLA
TH_3859|M.thermoresistible__bu      FTTPQHRLDDARRVRSTFFPTDDGLVRMGVALTELGMQPFTETQRELQTA
MSMEG_1181|M.smegmatis_MC2_155      PQLRFGDGDTATWAERADKLAAAPHAKIGAAIHSVRAVPPDSIAAVAEWA
                                                             .  . *       .          *

MMAR_2844|M.marinum_M               RDLGVRLHTHLSETVEEDEFCLAQFGSRPVDYVESLGWLGSDVWMAHCVH
MUL_2914|M.ulcerans_Agy99           RDLGVRLHTHLSETVEEDEFCLAQFGSRPVDYVESLGWLGSDVWMAHCVH
MAB_2927c|M.abscessus_ATCC_199      RERGVRLHTHLAETKDESVYCAERFGCSPLDYMEELGWLGPDVWFAHGVH
Mvan_3150|M.vanbaalenii_PYR-1       AEHGLRVHTHLAESKPQALAGASRFGHSITRELARLGVLGDRLTVAHAIW
TH_3859|M.thermoresistible__bu      EDLAVPVTMHTN-------CVWTRPEFHDVELYHRAGLLRAGQIHSHANR
MSMEG_1181|M.smegmatis_MC2_155      AQRDTPLHFHLSEQRAENDACLQAYGTTPTRLLAEHGALGANATAVHATH
                                     :    :  *                          * *       *   

MMAR_2844|M.marinum_M               LSKGDIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVAVGLGVDGA
MUL_2914|M.ulcerans_Agy99           LSKGYIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVAVGLGVDGA
MAB_2927c|M.abscessus_ATCC_199      FDDASIARLARTGTGIAHCPTSNGRLGAGIARVRELLAAGVPVGLGVDGA
Mvan_3150|M.vanbaalenii_PYR-1       VDDEDIRMLAASGAVAVTVPGSNLRLGSGIADTRAMLAAGLRLAVGTDGA
TH_3859|M.thermoresistible__bu      CSDHELALLRDAGCAVSSTPDTELQMGCGRPVFRRALATGVTAGIGID-I
MSMEG_1181|M.smegmatis_MC2_155      LTHTDITDLAGTGTTVCITPTTERDLADGIGPARELADAGCALSVGSD--
                                      .  :  *  :*      * ::  :. *         :.   .:* *  

MMAR_2844|M.marinum_M               GAEHRG-LANEMRQAALAAR------------FRLGP--QALDAREALWM
MUL_2914|M.ulcerans_Agy99           GAEHRG-LANEMRQAALAAR------------FRLGP--QALDAREALWM
MAB_2927c|M.abscessus_ATCC_199      ASNESGRLLEEAHQALLLAR------------AVGGP--TALSTRTALEL
Mvan_3150|M.vanbaalenii_PYR-1       NSADAFDALDAVRLTALLSR------------VSERPARQWLTVEETLDA
TH_3859|M.thermoresistible__bu      VSNNSGDMFTAMRVLMQHERGDALQPTLEESGLTAVAEPLPVTTRQILHA
MSMEG_1181|M.smegmatis_MC2_155      -SNAIVDIFEETRAVELDER-------------LRSEKRGHWTAAQLLTA
                                     :          :      *                       .   *  

MMAR_2844|M.marinum_M               ATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGHS--DVEDPVWALIY
MUL_2914|M.ulcerans_Agy99           ATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGHS--DVEDPVWALIY
MAB_2927c|M.abscessus_ATCC_199      ATLGGARLLGRSDEIGSIEVGKCADLVLWDLSTLGHS--GIEDPVAAVIL
Mvan_3150|M.vanbaalenii_PYR-1       ATAGGAAACG-WTDTGRLAPGRRADFALLDLGARAFR--PPTDLANQLLT
TH_3859|M.thermoresistible__bu      ATLAGARALGLESVCGSIDVGKSADLLLLRHDRLHMR--PVIDDIDSIVL
MSMEG_1181|M.smegmatis_MC2_155      ATADGHRALG-WSTAGRIAPGAAADLVTVSLDSVRLAGAEPETLLESVVF
                                    **  *    *     * :  *  **:     .               :: 

MMAR_2844|M.marinum_M               GP-PAPLRLLLVGGNTVVEDG-------------------------ELRT
MUL_2914|M.ulcerans_Agy99           GP-PAPLRLLLVGGNTVVEDG-------------------------ELRT
MAB_2927c|M.abscessus_ATCC_199      GE-VPPIRRSWVGGRPIVADG-------------------------QMLT
Mvan_3150|M.vanbaalenii_PYR-1       AARAADVTDVVVGGRFVYRDRGFPHLDVAAALNRFDTLVEEFRARVAPVR
TH_3859|M.thermoresistible__bu      QATTRDIDRVLVAGRTVVQDGRLPAAVE--------------RRGVAAIE
MSMEG_1181|M.smegmatis_MC2_155      AAHAGDVRDVVVSGRQVVADG---------------------------RH
                                          :    *.*. :  *                              

MMAR_2844|M.marinum_M               ADTETLATDAKNAAVTLRERG------------------------
MUL_2914|M.ulcerans_Agy99           ADTETLATDAKNAAVTLRERG------------------------
MAB_2927c|M.abscessus_ATCC_199      VDTERIAVAVRAAHHGLMNRER-----------------------
Mvan_3150|M.vanbaalenii_PYR-1       ADADRQTALAATALAGLRRAPSPVRRLIGWR--------------
TH_3859|M.thermoresistible__bu      AAHSRLAERVAAVGGWKLAVPQGLMDQLGVTFHDNVANTPAQANS
MSMEG_1181|M.smegmatis_MC2_155      TMVDDVPAALHAAIKDTLA--------------------------
                                    .  .  .     .