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GQASRSRVIPAPQQAIWDVLADFGALSSWVDKIDHSCVLNAHPEVLGTTRRVQVGRTVLVERITEYREPS TLAYAIEGLPAWMGRLTNRWTLRPAGVGTEVTVTSTVDPAGFASLVTSAVTARVLAKQSDAMLDGLARTM GART*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1287 | - | - | 100% (145) | cyclase/dehydrase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3103 | - | 9e-39 | 57.75% (142) | hypothetical protein Mb3103 |
| M. gilvum PYR-GCK | Mflv_2373 | - | 2e-21 | 41.67% (144) | hypothetical protein Mflv_2373 |
| M. tuberculosis H37Rv | Rv3076 | - | 9e-39 | 57.75% (142) | hypothetical protein Rv3076 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1578 | - | 1e-34 | 61.07% (131) | hypothetical protein MMAR_1578 |
| M. avium 104 | MAV_0977 | - | 2e-06 | 29.29% (140) | cyclase/dehydrase superfamily protein |
| M. thermoresistible (build 8) | TH_0121 | atsF | 4e-30 | 56.60% (106) | POSSIBLE HYDROLASE |
| M. ulcerans Agy99 | MUL_3456 | - | 1e-36 | 60.87% (138) | hypothetical protein MUL_3456 |
| M. vanbaalenii PYR-1 | Mvan_4273 | - | 5e-27 | 44.06% (143) | cyclase/dehydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3103|M.bovis_AF2122/97 MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
Rv3076|M.tuberculosis_H37Rv MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
MMAR_1578|M.marinum_M ----------------MAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MUL_3456|M.ulcerans_Agy99 ------MADISRSRTIVAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MSMEG_1287|M.smegmatis_MC2_155 ------MGQASRSRVIPAPQQAIWDVLADFGALSSWVDKIDHSCVLNAHP
Mflv_2373|M.gilvum_PYR-GCK ------MAAVSHSRQVAGDPIAIWTVLADFGGLHAWADRVDHCCLLNSR-
Mvan_4273|M.vanbaalenii_PYR-1 -MLNEAVAEVSRSRTVSAESAAIWARLADFGSLSAWADGIDHSCLLNGDD
TH_0121|M.thermoresistible__bu ------VAVFSRARTIPAGTERIWELLGDVGALSSWARLVDHSCVLTTGP
MAV_0977|M.avium_104 -----MAVKASREFVVNAPPEVVMEALTDVGVLSSWSPLHKHIEVIDRYP
. : * *.* * :* .* ::
Mb3103|M.bovis_AF2122/97 DGGA-LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRW
Rv3076|M.tuberculosis_H37Rv DGGA-LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRW
MMAR_1578|M.marinum_M DGEP-VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANHW
MUL_3456|M.ulcerans_Agy99 DGEP-VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANHW
MSMEG_1287|M.smegmatis_MC2_155 --EV-LGTTRRVQVGRTVLVERITEYREPSTLAYAIEGLPAWMGRLTNRW
Mflv_2373|M.gilvum_PYR-GCK --EPGIGLSRRVQSGRDTFVESITAFDPPRLLAYDISGVPSEFT-ASNRW
Mvan_4273|M.vanbaalenii_PYR-1 HPEP-VGLTRRIQSGRDTFVETIVAFEPSRVLGYEIAGVPKGFR-VSNRW
TH_0121|M.thermoresistible__bu HGDL-IGTTRRVQIGRTTLVERITEFDPPRALSYQICGLPPQLGNVVNRW
MAV_0977|M.avium_104 DGRP-HHVKTTIKILGLVDKEILEYHWGPDWVVYDAKGTSQQHG-QHVEY
. :: . * : . . : * * . .:
Mb3103|M.bovis_AF2122/97 TLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAKR------SN
Rv3076|M.tuberculosis_H37Rv TLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAKR------SN
MMAR_1578|M.marinum_M RLRRS---GNATIVELTSTVEVGTSRLAQMAERVALRVLAKQ------SD
MUL_3456|M.ulcerans_Agy99 RLRRS---GNATIVDLTSTVEVGTSRLAQMAERVALRVLAQQ------SD
MSMEG_1287|M.smegmatis_MC2_155 TLRPA---GVGTEVTVTSTVDPAG-FASLVTSAVTARVLAKQ------SD
Mflv_2373|M.gilvum_PYR-GCK DIGVH--RDGHTAVTLTSAATVTARCLPTGAERVFAHLVAHR------SK
Mvan_4273|M.vanbaalenii_PYR-1 NLEPR--AHGATTVTLTTTIRTSRALLRPLGERAFARLMARR------SD
TH_0121|M.thermoresistible__bu VLSPT---AGGTVVTLTTTVXXSRPDSGGRPDIVIVMTDEERAIPPYESD
MAV_0977|M.avium_104 NLKPE--GVGQTRVRFDVTVEPGRPMPAFIVRRASENVLDAAMKG--LQE
: * * . : . ..
Mb3103|M.bovis_AF2122/97 TMLAGLAQRLEDKHG-----------------------------------
Rv3076|M.tuberculosis_H37Rv TMLAGLAQRLEDKHG-----------------------------------
MMAR_1578|M.marinum_M AMLAGLASRLEKTHA-----------------------------------
MUL_3456|M.ulcerans_Agy99 AMLAGLASRLEKTHA-----------------------------------
MSMEG_1287|M.smegmatis_MC2_155 AMLDGLARTMGART------------------------------------
Mflv_2373|M.gilvum_PYR-GCK YLLDALDRTLRENP------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 SLLDSLAKATEGNP------------------------------------
TH_0121|M.thermoresistible__bu DLLAWRDQTLAGRRWFDEHGVTFTRHYTGSLACVPSRPTIFTGHYPDLHG
MAV_0977|M.avium_104 LVMRAKDLRDSGEAE-----------------------------------
::
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu VTQTDGLGKSHDDSRMRWLRRGEVPTLGHWFRAAGYDTHYDGKWHISHAD
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu LTDPRTGRPLATNDDDGVVDPAAVQRYLDADPLDPFGFSGWVGPEPHGAG
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu LANSGLRRDPLIADRVVAWLRDRYERRRAGDPDALRPFLLVASFVNPHDI
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu VLFPTWARRSPLSPGPLDPPPVPPAPTADEDLSDKPAAHIAFREAYYSGY
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu GPAWFVQRTYERNAQRYRDLYYRLHAEVDGPIDRVRRAVTAGSHNAVLVR
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu TSDHGELLGAHGGLHQKWFNLYDEATRVPFVIARIGDRATEARTVTAPTS
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu HVDLVPTLLGAAGVDVDAAAARLAESFTEVHPLPGRDLMPVVDGAPADEN
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu RAVYLMTRDSVLDGDTGASGLARQLNLTANPPGPLRIRVPAHVASNFEGL
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu VVCVEEATAAGGAGHLWKLVRTFDDPATWTEPGVRHLAADGLGGPAYRTD
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu PLDDQWELYDLTVDPIEAVNRWDDPGLDELRRHLRAQLKQARTVSVPERN
MAV_0977|M.avium_104 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 -----------
Rv3076|M.tuberculosis_H37Rv -----------
MMAR_1578|M.marinum_M -----------
MUL_3456|M.ulcerans_Agy99 -----------
MSMEG_1287|M.smegmatis_MC2_155 -----------
Mflv_2373|M.gilvum_PYR-GCK -----------
Mvan_4273|M.vanbaalenii_PYR-1 -----------
TH_0121|M.thermoresistible__bu EPWPYVRRQAR
MAV_0977|M.avium_104 -----------