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AAVSHSRQVAGDPIAIWTVLADFGGLHAWADRVDHCCLLNSREPGIGLSRRVQSGRDTFVESITAFDPPR LLAYDISGVPSEFTASNRWDIGVHRDGHTAVTLTSAATVTARCLPTGAERVFAHLVAHRSKYLLDALDRT LRENP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2373 | - | - | 100% (146) | hypothetical protein Mflv_2373 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3103 | - | 7e-22 | 41.26% (143) | hypothetical protein Mb3103 |
| M. tuberculosis H37Rv | Rv3076 | - | 7e-22 | 41.26% (143) | hypothetical protein Rv3076 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1578 | - | 4e-25 | 47.06% (136) | hypothetical protein MMAR_1578 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1287 | - | 2e-21 | 41.67% (144) | cyclase/dehydrase superfamily protein |
| M. thermoresistible (build 8) | TH_0121 | atsF | 1e-18 | 44.95% (109) | POSSIBLE HYDROLASE |
| M. ulcerans Agy99 | MUL_3456 | - | 7e-28 | 45.95% (148) | hypothetical protein MUL_3456 |
| M. vanbaalenii PYR-1 | Mvan_4273 | - | 3e-36 | 50.68% (148) | cyclase/dehydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3103|M.bovis_AF2122/97 MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
Rv3076|M.tuberculosis_H37Rv MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
MMAR_1578|M.marinum_M ----------------MAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MUL_3456|M.ulcerans_Agy99 ------MADISRSRTIVAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MSMEG_1287|M.smegmatis_MC2_155 ------MGQASRSRVIPAPQQAIWDVLADFGALSSWVDKIDHSCVLNAHP
TH_0121|M.thermoresistible__bu ------VAVFSRARTIPAGTERIWELLGDVGALSSWARLVDHSCVLTTGP
Mflv_2373|M.gilvum_PYR-GCK ------MAAVSHSRQVAGDPIAIWTVLADFGGLHAWADRVDHCCLLNSR-
Mvan_4273|M.vanbaalenii_PYR-1 -MLNEAVAEVSRSRTVSAESAAIWARLADFGSLSAWADGIDHSCLLNGDD
. ** *.*.*.* :*. :**.*:*.
Mb3103|M.bovis_AF2122/97 DGGA-LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRW
Rv3076|M.tuberculosis_H37Rv DGGA-LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRW
MMAR_1578|M.marinum_M DGEP-VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANHW
MUL_3456|M.ulcerans_Agy99 DGEP-VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANHW
MSMEG_1287|M.smegmatis_MC2_155 --EV-LGTTRRVQVGRTVLVERITEYREPSTLAYAIEGLPAWMGRLTNRW
TH_0121|M.thermoresistible__bu HGDL-IGTTRRVQIGRTTLVERITEFDPPRALSYQICGLPPQLGNVVNRW
Mflv_2373|M.gilvum_PYR-GCK --EPGIGLSRRVQSGRDTFVESITAFDPPRLLAYDISGVPSEFT-ASNRW
Mvan_4273|M.vanbaalenii_PYR-1 HPEP-VGLTRRIQSGRDTFVETIVAFEPSRVLGYEIAGVPKGFR-VSNRW
:* :**:* ** .:** : : . *.* * *:* : *:*
Mb3103|M.bovis_AF2122/97 TLRPADPVGAVTVVTLTSTI-----EIGGNPLARLAELVVGRAMAK-RSN
Rv3076|M.tuberculosis_H37Rv TLRPADPVGAVTVVTLTSTI-----EIGGNPLARLAELVVGRAMAK-RSN
MMAR_1578|M.marinum_M RLRRS---GNATIVELTSTV-----EVGTSRLAQMAERVALRVLAK-QSD
MUL_3456|M.ulcerans_Agy99 RLRRS---GNATIVDLTSTV-----EVGTSRLAQMAERVALRVLAQ-QSD
MSMEG_1287|M.smegmatis_MC2_155 TLRPA---GVGTEVTVTSTV-----DPAG-FASLVTSAVTARVLAK-QSD
TH_0121|M.thermoresistible__bu VLSPT---AGGTVVTLTTTVXXSRPDSGGRPDIVIVMTDEERAIPPYESD
Mflv_2373|M.gilvum_PYR-GCK DIGVH--RDGHTAVTLTSAA-----TVTARCLPTGAERVFAHLVAH-RSK
Mvan_4273|M.vanbaalenii_PYR-1 NLEPR--AHGATTVTLTTTI-----RTSRALLRPLGERAFARLMAR-RSD
: * * :*:: : :. .*.
Mb3103|M.bovis_AF2122/97 TMLAGLAQRLEDKHG-----------------------------------
Rv3076|M.tuberculosis_H37Rv TMLAGLAQRLEDKHG-----------------------------------
MMAR_1578|M.marinum_M AMLAGLASRLEKTHA-----------------------------------
MUL_3456|M.ulcerans_Agy99 AMLAGLASRLEKTHA-----------------------------------
MSMEG_1287|M.smegmatis_MC2_155 AMLDGLARTMGART------------------------------------
TH_0121|M.thermoresistible__bu DLLAWRDQTLAGRRWFDEHGVTFTRHYTGSLACVPSRPTIFTGHYPDLHG
Mflv_2373|M.gilvum_PYR-GCK YLLDALDRTLRENP------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 SLLDSLAKATEGNP------------------------------------
:*
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu VTQTDGLGKSHDDSRMRWLRRGEVPTLGHWFRAAGYDTHYDGKWHISHAD
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu LTDPRTGRPLATNDDDGVVDPAAVQRYLDADPLDPFGFSGWVGPEPHGAG
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu LANSGLRRDPLIADRVVAWLRDRYERRRAGDPDALRPFLLVASFVNPHDI
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu VLFPTWARRSPLSPGPLDPPPVPPAPTADEDLSDKPAAHIAFREAYYSGY
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu GPAWFVQRTYERNAQRYRDLYYRLHAEVDGPIDRVRRAVTAGSHNAVLVR
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu TSDHGELLGAHGGLHQKWFNLYDEATRVPFVIARIGDRATEARTVTAPTS
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu HVDLVPTLLGAAGVDVDAAAARLAESFTEVHPLPGRDLMPVVDGAPADEN
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu RAVYLMTRDSVLDGDTGASGLARQLNLTANPPGPLRIRVPAHVASNFEGL
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu VVCVEEATAAGGAGHLWKLVRTFDDPATWTEPGVRHLAADGLGGPAYRTD
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
TH_0121|M.thermoresistible__bu PLDDQWELYDLTVDPIEAVNRWDDPGLDELRRHLRAQLKQARTVSVPERN
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3103|M.bovis_AF2122/97 -----------
Rv3076|M.tuberculosis_H37Rv -----------
MMAR_1578|M.marinum_M -----------
MUL_3456|M.ulcerans_Agy99 -----------
MSMEG_1287|M.smegmatis_MC2_155 -----------
TH_0121|M.thermoresistible__bu EPWPYVRRQAR
Mflv_2373|M.gilvum_PYR-GCK -----------
Mvan_4273|M.vanbaalenii_PYR-1 -----------