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MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE RVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAK RSNTMLAGLAQRLEDKHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3076 | - | - | 100% (158) | hypothetical protein Rv3076 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3103 | - | 2e-87 | 100.00% (158) | hypothetical protein Mb3103 |
| M. gilvum PYR-GCK | Mflv_2373 | - | 1e-21 | 41.26% (143) | hypothetical protein Mflv_2373 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0831 | - | 5e-05 | 28.77% (146) | hypothetical protein MAB_0831 |
| M. marinum M | MMAR_1578 | - | 1e-47 | 64.29% (140) | hypothetical protein MMAR_1578 |
| M. avium 104 | MAV_2778 | - | 4e-05 | 27.87% (122) | hypothetical protein MAV_2778 |
| M. smegmatis MC2 155 | MSMEG_1287 | - | 2e-38 | 57.75% (142) | cyclase/dehydrase superfamily protein |
| M. thermoresistible (build 8) | TH_0121 | atsF | 3e-31 | 54.62% (119) | POSSIBLE HYDROLASE |
| M. ulcerans Agy99 | MUL_3456 | - | 5e-51 | 63.58% (151) | hypothetical protein MUL_3456 |
| M. vanbaalenii PYR-1 | Mvan_4273 | - | 3e-31 | 45.10% (153) | cyclase/dehydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3076|M.tuberculosis_H37Rv MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
Mb3103|M.bovis_AF2122/97 MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGP
MMAR_1578|M.marinum_M ----------------MAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MUL_3456|M.ulcerans_Agy99 ------MADISRSRTIVAEPQAIWNVLADFGALSTWADGIDHSCVLNEGP
MSMEG_1287|M.smegmatis_MC2_155 ------MGQASRSRVIPAPQQAIWDVLADFGALSSWVDKIDHSCVLNAHP
Mflv_2373|M.gilvum_PYR-GCK ------MAAVSHSRQVAGDPIAIWTVLADFGGLHAWADRVDHCCLLNSR-
Mvan_4273|M.vanbaalenii_PYR-1 -MLNEAVAEVSRSRTVSAESAAIWARLADFGSLSAWADGIDHSCLLNGDD
TH_0121|M.thermoresistible__bu ------VAVFSRARTIPAGTERIWELLGDVGALSSWARLVDHSCVLTTGP
MAB_0831|M.abscessus_ATCC_1997 -----MATSDTREIVIEATPEQIMDVIADFEVLPKWSSAHQSSTVLTTGE
MAV_2778|M.avium_104 --MPGRKFSFEVTRTSSAPAATLFRLVADGANWSRWAKPIVLHSSWARQG
. : :.* *
Rv3076|M.tuberculosis_H37Rv DGGA--LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNR
Mb3103|M.bovis_AF2122/97 DGGA--LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNR
MMAR_1578|M.marinum_M DGEP--VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANH
MUL_3456|M.ulcerans_Agy99 DGEP--VGTTRRVQVGRNTLVERITAFDPPTSLAYDIEGLPNRLRKVANH
MSMEG_1287|M.smegmatis_MC2_155 --EV--LGTTRRVQVGRTVLVERITEYREPSTLAYAIEGLPAWMGRLTNR
Mflv_2373|M.gilvum_PYR-GCK --EPG-IGLSRRVQSGRDTFVESITAFDPPRLLAYDISGVPSEFT-ASNR
Mvan_4273|M.vanbaalenii_PYR-1 HPEP--VGLTRRIQSGRDTFVETIVAFEPSRVLGYEIAGVPKGFR-VSNR
TH_0121|M.thermoresistible__bu HGDL--IGTTRRVQIGRTTLVERITEFDPPRALSYQICGLPPQLGNVVNR
MAB_0831|M.abscessus_ATCC_1997 DGRP--HQVTMKVKTAGITDEQTVAYTWGPDTVSWTLVKAS-QQRRQDGK
MAV_2778|M.avium_104 DPAPGGVGAIRKVGLWPVLVQEETTEYEPDRRHAYKLVGPPSPAKDYTGE
:: : .: : . ..
Rv3076|M.tuberculosis_H37Rv WTLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAKR------S
Mb3103|M.bovis_AF2122/97 WTLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAKR------S
MMAR_1578|M.marinum_M WRLRRS---GNATIVELTSTVEVGTSRLAQMAERVALRVLAKQ------S
MUL_3456|M.ulcerans_Agy99 WRLRRS---GNATIVDLTSTVEVGTSRLAQMAERVALRVLAQQ------S
MSMEG_1287|M.smegmatis_MC2_155 WTLRPA---GVGTEVTVTSTVDPAG-FASLVTSAVTARVLAKQ------S
Mflv_2373|M.gilvum_PYR-GCK WDIGVH--RDGHTAVTLTSAATVTARCLPTGAERVFAHLVAHR------S
Mvan_4273|M.vanbaalenii_PYR-1 WNLEPR--AHGATTVTLTTTIRTSRALLRPLGERAFARLMARR------S
TH_0121|M.thermoresistible__bu WVLSPT---AGGTVVTLTTTVXXSRPDSGGRPDIVIVMTDEERAIPPYES
MAB_0831|M.abscessus_ATCC_1997 YTFTPQ---GDKTHVKFELTVDPLIPLPGFVLKRAIKGAMETA------T
MAV_2778|M.avium_104 VVFTPN--PAGGTDIRWTGSFTEGVRGTGPLMRAAMGGAVKFF------A
: * : : . :
Rv3076|M.tuberculosis_H37Rv NTMLAGLAQRLEDKHG----------------------------------
Mb3103|M.bovis_AF2122/97 NTMLAGLAQRLEDKHG----------------------------------
MMAR_1578|M.marinum_M DAMLAGLASRLEKTHA----------------------------------
MUL_3456|M.ulcerans_Agy99 DAMLAGLASRLEKTHA----------------------------------
MSMEG_1287|M.smegmatis_MC2_155 DAMLDGLARTMGART-----------------------------------
Mflv_2373|M.gilvum_PYR-GCK KYLLDALDRTLRENP-----------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 DSLLDSLAKATEGNP-----------------------------------
TH_0121|M.thermoresistible__bu DDLLAWRDQTLAGRRWFDEHGVTFTRHYTGSLACVPSRPTIFTGHYPDLH
MAB_0831|M.abscessus_ATCC_1997 DGLRKQVLATYR--------------------------------------
MAV_2778|M.avium_104 GRLVKAAEREAGQAR-----------------------------------
:
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu GVTQTDGLGKSHDDSRMRWLRRGEVPTLGHWFRAAGYDTHYDGKWHISHA
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu DLTDPRTGRPLATNDDDGVVDPAAVQRYLDADPLDPFGFSGWVGPEPHGA
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu GLANSGLRRDPLIADRVVAWLRDRYERRRAGDPDALRPFLLVASFVNPHD
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu IVLFPTWARRSPLSPGPLDPPPVPPAPTADEDLSDKPAAHIAFREAYYSG
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu YGPAWFVQRTYERNAQRYRDLYYRLHAEVDGPIDRVRRAVTAGSHNAVLV
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu RTSDHGELLGAHGGLHQKWFNLYDEATRVPFVIARIGDRATEARTVTAPT
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu SHVDLVPTLLGAAGVDVDAAAARLAESFTEVHPLPGRDLMPVVDGAPADE
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu NRAVYLMTRDSVLDGDTGASGLARQLNLTANPPGPLRIRVPAHVASNFEG
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu LVVCVEEATAAGGAGHLWKLVRTFDDPATWTEPGVRHLAADGLGGPAYRT
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv --------------------------------------------------
Mb3103|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1578|M.marinum_M --------------------------------------------------
MUL_3456|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1287|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2373|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4273|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0121|M.thermoresistible__bu DPLDDQWELYDLTVDPIEAVNRWDDPGLDELRRHLRAQLKQARTVSVPER
MAB_0831|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2778|M.avium_104 --------------------------------------------------
Rv3076|M.tuberculosis_H37Rv ------------
Mb3103|M.bovis_AF2122/97 ------------
MMAR_1578|M.marinum_M ------------
MUL_3456|M.ulcerans_Agy99 ------------
MSMEG_1287|M.smegmatis_MC2_155 ------------
Mflv_2373|M.gilvum_PYR-GCK ------------
Mvan_4273|M.vanbaalenii_PYR-1 ------------
TH_0121|M.thermoresistible__bu NEPWPYVRRQAR
MAB_0831|M.abscessus_ATCC_1997 ------------
MAV_2778|M.avium_104 ------------