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VAVKASREFVVNAPPEVVMEALTDVGVLSSWSPLHKHIEVIDRYPDGRPHHVKTTIKILGLVDKEILEYH WGPDWVVYDAKGTSQQHGQHVEYNLKPEGVGQTRVRFDVTVEPGRPMPAFIVRRASENVLDAAMKGLQEL VMRAKDLRDSGEAE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0977 | - | - | 100% (154) | cyclase/dehydrase superfamily protein |
| M. avium 104 | MAV_0978 | - | 6e-50 | 60.56% (142) | hypothetical protein MAV_0978 |
| M. avium 104 | MAV_0975 | - | 1e-24 | 33.10% (145) | cyclase/dehydrase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0879 | - | 7e-56 | 74.22% (128) | hypothetical protein Mb0879 |
| M. gilvum PYR-GCK | Mflv_1679 | - | 7e-47 | 56.25% (144) | cyclase/dehydrase |
| M. tuberculosis H37Rv | Rv0856 | - | 7e-56 | 74.22% (128) | hypothetical protein Rv0856 |
| M. leprae Br4923 | MLBr_00889 | - | 2e-10 | 25.34% (146) | hypothetical protein MLBr_00889 |
| M. abscessus ATCC 19977 | MAB_0831 | - | 1e-25 | 36.62% (142) | hypothetical protein MAB_0831 |
| M. marinum M | MMAR_4680 | - | 2e-63 | 78.72% (141) | hypothetical protein MMAR_4680 |
| M. smegmatis MC2 155 | MSMEG_5736 | - | 2e-27 | 36.55% (145) | cyclase/dehydrase |
| M. thermoresistible (build 8) | TH_3096 | - | 4e-45 | 53.85% (143) | PUTATIVE cyclase/dehydrase |
| M. ulcerans Agy99 | MUL_0299 | - | 1e-62 | 78.01% (141) | hypothetical protein MUL_0299 |
| M. vanbaalenii PYR-1 | Mvan_5071 | - | 4e-49 | 61.81% (144) | cyclase/dehydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0879|M.bovis_AF2122/97 ---------------------MEALADVGVLASWSPLHKQVEVIDYYPDG
Rv0856|M.tuberculosis_H37Rv ---------------------MEALADVGVLASWSPLHKQVEVIDYYPDG
MMAR_4680|M.marinum_M MNLVAVKAAREFVIDAPPEVVMEALTDVGVLVSWSPLHKSVEVIDYYPDG
MUL_0299|M.ulcerans_Agy99 ---MAVKAAREFVIDAPPEVVMEALTDVGVLVSWSPLHKSVEVIDYYPDG
MAV_0977|M.avium_104 ---MAVKASREFVVNAPPEVVMEALTDVGVLSSWSPLHKHIEVIDRYPDG
Mvan_5071|M.vanbaalenii_PYR-1 ---MAIRASREVLIEAPRDAVMEALADVGALPSYSSMHKRAEVMDRYPDG
Mflv_1679|M.gilvum_PYR-GCK ---MAVRASSELVIEAPPEAIMDALADIESVVSWSSLHKDAEIVDRHPDG
TH_3096|M.thermoresistible__bu ---MAVRASREVVIDAPVEAILDVLADIDQVPSWSTLHRRAEVLDRHPDG
MAB_0831|M.abscessus_ATCC_1997 ---MATSDTREIVIEATPEQIMDVIADFEVLPKWSSAHQSSTVLTTGEDG
MSMEG_5736|M.smegmatis_MC2_155 ---MATSDSREVLIEASPEEILDVIADVESTPSWSPQYTHAEITERYDDG
MLBr_00889|M.leprae_Br4923 ---MADKTTQTFYIDANPGEVMKTIADIESYPQWISEYKEVEVLEVDDED
:..::*. .: . : : :.
Mb0879|M.bovis_AF2122/97 RPHHVRATVKILGLVDKEVLEYHWGPDW--VCWDADQTFQQHGQHIEYTV
Rv0856|M.tuberculosis_H37Rv RPHHVRATVKILGLVDKEVLEYHWGPDW--VCWDADQTFQQHGQHIEYTV
MMAR_4680|M.marinum_M RPHHVKATIKILGLVDKEILEYHWGPDW--VCWDADQTFQQRGQHVEYTV
MUL_0299|M.ulcerans_Agy99 RPHHVKATIKILGLVDKEILEYHWGPDW--VCWDADQTFQQRGQHVEYTV
MAV_0977|M.avium_104 RPHHVKTTIKILGLVDKEILEYHWGPDW--VVYDAKGTSQQHGQHVEYNL
Mvan_5071|M.vanbaalenii_PYR-1 RPHHVRVKIRLLGLVDTEILEYRWGPDW--LVWDAQPTSQQYAQHVEYRL
Mflv_1679|M.gilvum_PYR-GCK RPHHVRATVKIMGLSDQEMLEYHWGDDW--VVWDAEQTSRQRCQHGEYNL
TH_3096|M.thermoresistible__bu RPHHVRATLRILGVTDRQILEYHWGPSW--MVWDAEETFQQRGQHGEYNL
MAB_0831|M.abscessus_ATCC_1997 RPHQVTMKVKTAGITDEQTVAYTWGPDT--VSWTLVKASQQRRQDGKYTF
MSMEG_5736|M.smegmatis_MC2_155 RPRRAKMTVKAAGLTDDQVIEYTWSENK--VSWTLVSAGQLKAQDASYTL
MLBr_00889|M.leprae_Br4923 FPKRARMLMDAKIFKDTLIMSYDWTADHQSVSWILESSSLLKSLEGSYRL
*::. : . * : * * . : : : . .* .
Mb0879|M.bovis_AF2122/97 KPEGVDR-ARVRFDITVEPAGPIPGFIVKRASEHVLDAAAKGLQKLIAGA
Rv0856|M.tuberculosis_H37Rv KPEGVDR-ARVRFDITVEPAGPIPGFIVKRASEHVLDAAAKGLQKLIAGA
MMAR_4680|M.marinum_M RPEGLDK-SRVRFDITVEPSGPIPGFIVKRASEHVLDAAAKGLSELVANR
MUL_0299|M.ulcerans_Agy99 RPEGLDK-SRVRFDITVEPSGPISGFIVKRASEHVLDAAAKGLSELVANR
MAV_0977|M.avium_104 KPEGVGQ-TRVRFDVTVEPGRPMPAFIVRRASENVLDAAMKGLQELVMRA
Mvan_5071|M.vanbaalenii_PYR-1 SSDDHGECTRVRIDITVEPVVPIPEFLIRRACGGVLDAATTGLRELALRD
Mflv_1679|M.gilvum_PYR-GCK TPVGEER-TRVRFDLILDLAAPYPTFLVRRAKQMVLDIALQNLRQRVL--
TH_3096|M.thermoresistible__bu TPVGQDR-TRVRFDLIMELAAPVPHFLIKRGRRIVLDVATEKLKERVYRC
MAB_0831|M.abscessus_ATCC_1997 TPQG-DK-THVKFELTVDPLIPLPGFVLKRAIKGAMETATDGLRKQVLAT
MSMEG_5736|M.smegmatis_MC2_155 TPQG-DK-TKVRFDISIDLSVPLPGFIVKRTMKGGVETATDGLRKQVLKV
MLBr_00889|M.leprae_Br4923 VPKGSTT--EVTYELAVDFAIPMIGMLKRKAEHRLIDGALKDLKKRVEG-
. . .* :: :: * :: :: :: * * :
Mb0879|M.bovis_AF2122/97 G---DQGNAKS-
Rv0856|M.tuberculosis_H37Rv G---DQGNAKS-
MMAR_4680|M.marinum_M D---ATDQAK--
MUL_0299|M.ulcerans_Agy99 D---ATDQAK--
MAV_0977|M.avium_104 KDLRDSGEAE--
Mvan_5071|M.vanbaalenii_PYR-1 A-----GT----
Mflv_1679|M.gilvum_PYR-GCK ------AATQ--
TH_3096|M.thermoresistible__bu L---GSSAPKRT
MAB_0831|M.abscessus_ATCC_1997 Y------R----
MSMEG_5736|M.smegmatis_MC2_155 K------KG---
MLBr_00889|M.leprae_Br4923 ------------