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M. thermoresistible (build 8) TH_0121 (atsF)

annotation: POSSIBLE HYDROLASE
coordinates: 221915 - 224020
length: 702

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0121atsF-100% (702)POSSIBLE HYDROLASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3104-0.081.90% (580) hydrolase
M. gilvum PYR-GCKMflv_2372-0.082.99% (582) sulfatase
M. tuberculosis H37RvRv3077-0.081.72% (580) hydrolase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4469c-2e-2829.95% (414) sulfatase family protein
M. marinum MMMAR_1577-0.081.90% (580) hydrolase
M. avium 104MAV_4858-7e-0823.54% (446) sulfatase family protein
M. smegmatis MC2 155MSMEG_1286-0.083.10% (580) sulfatase family protein
M. ulcerans Agy99MUL_3457-0.081.21% (580) hydrolase
M. vanbaalenii PYR-1Mvan_4274-0.081.71% (585) sulfatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3104|M.bovis_AF2122/97            --------------------------------------------------
Rv3077|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1577|M.marinum_M               --------------------------------------------------
MUL_3457|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_1286|M.smegmatis_MC2_155      --------------------------------------------------
TH_0121|M.thermoresistible__bu      VAVFSRARTIPAGTERIWELLGDVGALSSWARLVDHSCVLTTGPHGDLIG
Mflv_2372|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4274|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4469c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4858|M.avium_104                --------------------------------------------------
                                                                                      

Mb3104|M.bovis_AF2122/97            --------------------------------------------------
Rv3077|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1577|M.marinum_M               --------------------------------------------------
MUL_3457|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_1286|M.smegmatis_MC2_155      --------------------------------------------------
TH_0121|M.thermoresistible__bu      TTRRVQIGRTTLVERITEFDPPRALSYQICGLPPQLGNVVNRWVLSPTAG
Mflv_2372|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4274|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4469c|M.abscessus_ATCC_199      -------------------------MAELNRRTVLTTGAIAAGAAAVGFG
MAV_4858|M.avium_104                --------------------------------------------------
                                                                                      

Mb3104|M.bovis_AF2122/97            ----------------MANRPDIIIVMTDEE-RAVPPYESAEVLAWRQRS
Rv3077|M.tuberculosis_H37Rv         ----------------MANRPDIIIVMTDEE-RAVPPYESAEVLAWRQRS
MMAR_1577|M.marinum_M               ----------------MPEGPDIVIIMTDEE-RAVPPYESADVLAWRQRT
MUL_3457|M.ulcerans_Agy99           ----------------MPEGPDIVIIMTDEE-RAVPPYESADVLAWRQRT
MSMEG_1286|M.smegmatis_MC2_155      ----------------MTDRPDIVIVMTDEE-RAIPPYESSSVLAWRERV
TH_0121|M.thermoresistible__bu      GTVVTLTTTVXXSRPDSGGRPDIVIVMTDEE-RAIPPYESDDLLAWRDQT
Mflv_2372|M.gilvum_PYR-GCK          ---------------MTAQRPDVVIVMTDEE-RAIPPYESDRVRTWRDET
Mvan_4274|M.vanbaalenii_PYR-1       ---------------MTTERPDIVVVMTDEE-RATPPYEPDTVRAWRSRT
MAB_4469c|M.abscessus_ATCC_199      GYELLGTPRRNSSSGSDGNKPNILVIVVDQM-RAPQWFPDVQKLTN---I
MAV_4858|M.avium_104                --MTQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYG------HRDVS
                                                         :::::  .:  *    :            

Mb3104|M.bovis_AF2122/97            LTGRRWFDEHGISFTRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGK
Rv3077|M.tuberculosis_H37Rv         LTGRRWFDEHGISFTRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGK
MMAR_1577|M.marinum_M               LTGRRWFDEHGVSFARHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGK
MUL_3457|M.ulcerans_Agy99           LTGRRWFDEHGVSFARHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGK
MSMEG_1286|M.smegmatis_MC2_155      LTGRRWFDEHGVNFTRHYTGSLACVPSRPTMFTGHYPDLHGITQTDGLGK
TH_0121|M.thermoresistible__bu      LAGRRWFDEHGVTFTRHYTGSLACVPSRPTIFTGHYPDLHGVTQTDGLGK
Mflv_2372|M.gilvum_PYR-GCK          LTGRRWFEEHGVSFTRHYTGSLACVPSRPTIFTGHYPDLHGVTQTDGIGK
Mvan_4274|M.vanbaalenii_PYR-1       LGGRRWFDENGVSFLRHYTGSLACVPSRPTIFTGQYPDLHGVTQTDGIGK
MAB_4469c|M.abscessus_ATCC_199      LPNLSRLHRDSVSFASHYTASNMCTPSRGAMTTGLYSHQTGCLYTG----
MAV_4858|M.avium_104                SPRLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQTNGLIGLAHHG-
                                          :  ..: *   :: :  * *** :: ** *..  *         

Mb3104|M.bovis_AF2122/97            RFDDSRLRWLRAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGAP
Rv3077|M.tuberculosis_H37Rv         RFDDSRLRWLRAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGAP
MMAR_1577|M.marinum_M               RFDDSRLRWLRAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPDTGLS
MUL_3457|M.ulcerans_Agy99           RFDDSRLRWLRAGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPDTGLS
MSMEG_1286|M.smegmatis_MC2_155      RYDDSRLRWLRRGEVPTLGNWFRAAGYDTHYDGKWHISHADLEDPATGEP
TH_0121|M.thermoresistible__bu      SHDDSRMRWLRRGEVPTLGHWFRAAGYDTHYDGKWHISHADLTDPRTGRP
Mflv_2372|M.gilvum_PYR-GCK          SHDDSRLRWLRRGEVPTLGNWFRAAGYDTHYDGKWHISHADLTDPSTGRP
Mvan_4274|M.vanbaalenii_PYR-1       AHDDSRLRWLRRGEVPTLGNWLRAAGYDTHYDGKWHISHADLIDPGTGRS
MAB_4469c|M.abscessus_ATCC_199      ---EGPSESSLAPQFPTWGTMLRQQGYRTWWWGKWHLGDWSDTNP-----
MAV_4858|M.avium_104                --------WEYRSGIRTLPQILSEAGWYSALFGMQHETSY----------
                                                  . *    :   *: :   *  *              

Mb3104|M.bovis_AF2122/97            LATNDNEGVVDSAAVRRYLDADPLGPYGFSGWVGPEPHGAGLANSGFRRD
Rv3077|M.tuberculosis_H37Rv         LATNDNEGVVDSAAVRRYLDADPLGPYGFSGWVGPEPHGAGLANSGFRRD
MMAR_1577|M.marinum_M               LATNDDDGEIDPAAVQRYLDADPLGPYGFSGWVGPEPHGAGNANSGFRRD
MUL_3457|M.ulcerans_Agy99           LATNDDDGEIDPAAVQRYLDADPLGPYGFSGWVGPEPHGAGNANSGFRRD
MSMEG_1286|M.smegmatis_MC2_155      LATNDDDGVIDHAAVQAYLEADPLAPFGFSGWVGPEPHGAAMSNSGFRRD
TH_0121|M.thermoresistible__bu      LATNDDDGVVDPAAVQRYLDADPLDPFGFSGWVGPEPHGAGLANSGLRRD
Mflv_2372|M.gilvum_PYR-GCK          LATNDSDGVVDPGAVKRYLDADPLAPYGFSGWVGPEPHGAGLANAGIRRD
Mvan_4274|M.vanbaalenii_PYR-1       LDTNDDDGVVDPAAVHRYLEADPLSPYGFSGWVGPEPHGAKLSNAGIRRD
MAB_4469c|M.abscessus_ATCC_199      ---------------------EGLDAHGFSGGTFPSPN--GMPNQGLQKD
MAV_4858|M.avium_104                ----------------------------------PKRLGFDEFDVSNSYC
                                                                      *.       : .    

Mb3104|M.bovis_AF2122/97            PLVADRVVAWLTERYARRRAGDTAAMRPFLLVASFVNPHDIVLFPAWVWR
Rv3077|M.tuberculosis_H37Rv         PLVADRVVAWLTERYARRRAGDTAAMRPFLLVASFVNPHDIVLFPAWVWR
MMAR_1577|M.marinum_M               PLIADRVVAWLEDRYARRRAGDEAALRPFLLVASFINPHDVVLFPAWVRF
MUL_3457|M.ulcerans_Agy99           PLIADRVVAWLEDRYARRRAGDEAALRPFLLVASFINPHDVVLFPAWVRF
MSMEG_1286|M.smegmatis_MC2_155      PIVADRVVAWLKDRYARRRAGDPDALRPFLLVASFVNPHDIVLFPAWSRR
TH_0121|M.thermoresistible__bu      PLIADRVVAWLRDRYERRRAGDPDALRPFLLVASFVNPHDIVLFPTWARR
Mflv_2372|M.gilvum_PYR-GCK          PLIADRVVAWLTARYAARAAGDSAALRPFLLVASFVNPHDIVLFPAWARR
Mvan_4274|M.vanbaalenii_PYR-1       PLIADRVVAWLKDRYARRRAGDPDAMRPFLLVASFVNPHDIVLFPAWARR
MAB_4469c|M.abscessus_ATCC_199      PGIVDQFAGWFDAEAGKG---------PWCTTVSLVNPHDICWWPKNP-L
MAV_4858|M.avium_104                DYVAQRADEWLRQSAEGVVG------QPFLLTAGFFETHRP--YPEDRYP
                                      :.::   *:                *:  ...:.:.*    :*     

Mb3104|M.bovis_AF2122/97            SPLKPSPLDPPHVPAAPTADEDLSTKPAAQVAYREAYYSGYGLTRMVSR-
Rv3077|M.tuberculosis_H37Rv         SPLKPSPLDPPHVPAAPTADEDLSTKPAAQVAYREAYYSGYGLTRMVSR-
MMAR_1577|M.marinum_M               SPLKPSHLDPPHVPAPPTADEDLRTKPAAQIAFRQAYYTGYGVAPAIKR-
MUL_3457|M.ulcerans_Agy99           GPLKPSHLDPPHVPAPPTADEDLRTKPAAQIAFRQAYYTGYGVAPAIKR-
MSMEG_1286|M.smegmatis_MC2_155      MPFGPSELDPPHVPAAPTAEEDLRDKPAAQIAFREAYYTGYGPAMAVER-
TH_0121|M.thermoresistible__bu      SPLSPGPLDPPPVPPAPTADEDLSDKPAAHIAFREAYYSGYGPAWFVQR-
Mflv_2372|M.gilvum_PYR-GCK          NPLSPSPLDPPSVPPAPTADEDLSTKPAAQIAFREAYYSGYGPAGSIER-
Mvan_4274|M.vanbaalenii_PYR-1       NPLPASPLDPPPVPAAPTADEDLSTKPAAQIAFREAYYSGYGPAWSIER-
MAB_4469c|M.abscessus_ATCC_199      PEDVPHWFDGLPVNFQTPDELRQHGKPRLQIDYANFMSPIMTGAVTYSGP
MAV_4858|M.avium_104                PADSAEVQPPDYLPDTPEVRGDLAA-------------------------
                                        .       :   .                                 

Mb3104|M.bovis_AF2122/97            NYARNAQRYRDLYYRLHAEVDGPIDRVRRAVTEGG----SEDAMLVRTSD
Rv3077|M.tuberculosis_H37Rv         NYARNAQRYRDLYYRLHAEVDGPIDRVGRAVTEGG----SEDAMLVRTSD
MMAR_1577|M.marinum_M               TYQRNAQRYRDLYYRLHAENDGPIDRVRRAVTEGG----SDNAVLVRTSD
MUL_3457|M.ulcerans_Agy99           TYQRNAQRYRDLYYRLHAENDGPIDRVRRAVTEGG----SDNAVLVRTSD
MSMEG_1286|M.smegmatis_MC2_155      TYRRKAQQYRDLYYRLHAEVDGPIDRVRRAVTEGG----SENAVLVRTSD
TH_0121|M.thermoresistible__bu      TYERNAQRYRDLYYRLHAEVDGPIDRVRRAVTAG-----SHNAVLVRTSD
Mflv_2372|M.gilvum_PYR-GCK          TYRRNAQRYRDLYYRLHAEVDEPIDRVRRAVTDG---AGAHPTVLVRTAD
Mvan_4274|M.vanbaalenii_PYR-1       TYRRNAQRYRDLYYRLHAEVDTPIDRVRRAVTEGGSGDGPDDTVLVRTAD
MAB_4469c|M.abscessus_ATCC_199      DMARQWARCLDMYLWLQQQVDAQIGRVLDKLASRP--EIDGNTIVVFTSD
MAV_4858|M.avium_104                ------------FYGAISTADAAVGRLLDTLADTG---LDASTWVVFFTD
                                                :       *  :.*:   ::          : :*  :*

Mb3104|M.bovis_AF2122/97            HGDLLGAHGGLHQKWFNLYDEATRVPFVIARIG--EKATQPRTVSAPTSH
Rv3077|M.tuberculosis_H37Rv         HGDLLGAHGGLHQKWFNLYDEATRVPFVIARIG--EKATQPRTVSAPTSH
MMAR_1577|M.marinum_M               HGDLLGAHGGLHQKWFNLYDEATRVPFVIARVG--DEATTARTVSAPTSH
MUL_3457|M.ulcerans_Agy99           HGDLLGAHGGLHQKWFNLYDEATRVPFVITRVG--NEATTARTVSAPTSH
MSMEG_1286|M.smegmatis_MC2_155      HGELLGAHGGLHQKWFNLYDEATRVPFVIARIG--TEATEARTVDAPTSH
TH_0121|M.thermoresistible__bu      HGELLGAHGGLHQKWFNLYDEATRVPFVIARIG--DRATEARTVTAPTSH
Mflv_2372|M.gilvum_PYR-GCK          HGDLLGAHGGLHQKWFNLYDEATRVPFVIARTG--PDATTARTVTAPTSH
Mvan_4274|M.vanbaalenii_PYR-1       HGDLLGAHGGLHQKWFNLYDEATRVPFVIARVG--ARPTTARTVTAPTSH
MAB_4469c|M.abscessus_ATCC_199      HGEYAGSHG-LRGKGATAYEEAIRVPLYIRDPQGVLTPKPGETRTQLTSS
MAV_4858|M.avium_104                HG------PAFPRAKSTLYDAGTGIGMIVRPPTG--RGLPPRVYDELFSA
                                    **        :     . *: .  : : :            ..     * 

Mb3104|M.bovis_AF2122/97            VDLVPTLLSAAGVDVDVVAAALAESFSEVHPLPGRDLMPVVDGASADEGR
Rv3077|M.tuberculosis_H37Rv         VDLVPTLLSAAGVDVDVVAAALAESFSEVHPLPGRDLMPVVDGASADEGR
MMAR_1577|M.marinum_M               VDLVPTLLSAAGIDTDAVAANLAESFTEVHPLPGRDLMAVVDGAPADEDR
MUL_3457|M.ulcerans_Agy99           VDLVPTLLSAAGIDTEAVAANLAESFTEVHPLPGRDLMAVVDGAPADEDR
MSMEG_1286|M.smegmatis_MC2_155      VDLVPTLLGAAGVDVDAAAEQLRESFSEVHPLPGRDLMPVVSGESADEHR
TH_0121|M.thermoresistible__bu      VDLVPTLLGAAGVDVDAAAARLAESFTEVHPLPGRDLMPVVDGAPADENR
Mflv_2372|M.gilvum_PYR-GCK          VDLVPTLLAAAGIDAESVAATLGESFTEVHPLPGRDLMPVVDGAPADEDR
Mvan_4274|M.vanbaalenii_PYR-1       VDLVPTLLSAAGVDVDAAATVLAESFSEVHPLPGSDLMPVVDGAPADDHR
MAB_4469c|M.abscessus_ATCC_199      VDLAPLLLTIG------SGGNAWRSDPRFSYLAARADIAAIAKNNAAGRK
MAV_4858|M.avium_104                VDLVPTLLGLLGISVPPDVDGVSHASALLRPDP---------DAAPVREH
                                    ***.* **               .: . .   .            .   :

Mb3104|M.bovis_AF2122/97            AIYLMTRDNVLEGDTGASLLSRQLGRIVNPPAPLRIKVPAHVAANFEGLV
Rv3077|M.tuberculosis_H37Rv         AIYLMTRDNVLEGDTGASLLSRQLGRIVNPPAPLRIKVPAHVAANFEGLV
MMAR_1577|M.marinum_M               AIYLMTRDNVLEGDTGASLLSRQLGRTVNPPAPLRIKLPAHVAANFEGLV
MUL_3457|M.ulcerans_Agy99           AIYLMTRDNVLEGDTGASLLSRQLGRTVNPPAPLRIKLPAHVAANFEGLV
MSMEG_1286|M.smegmatis_MC2_155      PIYLMTRDNVLEGDTGASGVARQLGRDVNPPAPLRIKVPAHVASNFEGLV
TH_0121|M.thermoresistible__bu      AVYLMTRDSVLDGDTGASGLARQLNLTANPPGPLRIRVPAHVASNFEGLV
Mflv_2372|M.gilvum_PYR-GCK          PVYLMTRDNVLEGDTGASGLARALRLTSRVPAPLRIRVPAHTAANFEGLV
Mvan_4274|M.vanbaalenii_PYR-1       CVYLMTRDNVLEGDTGASGLARALKLTSKVPAPLRIRIPAHTAANFEGLV
MAB_4469c|M.abscessus_ATCC_199      WIAHVTDDMSVEEMA-------TLLKDPRIRAVMGENAPTEIPTSAASHI
MAV_4858|M.avium_104                VYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLELPWDIEESPSGMAVA
                                         * .  .:                     :      . ...  .  

Mb3104|M.bovis_AF2122/97            VRVDDTDAAGGAGHLWKLVRTFDDPATWTEPGVRHLATN-GMGGDAYRTD
Rv3077|M.tuberculosis_H37Rv         VRVDDTDAAGGAGHLWKLVRTFDDPATWTEPGVRHLATN-GMGGDAYRTD
MMAR_1577|M.marinum_M               VRVEDSDAPGGAGHLWKLVRTFDDPATWTEPGVRHLASN-GVGGETYRTD
MUL_3457|M.ulcerans_Agy99           VRVEDSDAPGGAGHLWKLVRTFDDPATWTEPGVRHLASN-GVGGETYRTD
MSMEG_1286|M.smegmatis_MC2_155      VRVDDADAHGGAGHLWKLVRTFDDPSTWTEPGVRHLAAD-GLGGETYRSD
TH_0121|M.thermoresistible__bu      VCVEEATAAGGAGHLWKLVRTFDDPATWTEPGVRHLAAD-GLGGPAYRTD
Mflv_2372|M.gilvum_PYR-GCK          LRVPETSAAGGGGHLWKLVRSFDDPGTWTEPGVRQLAAD-GVGGPTYRSE
Mvan_4274|M.vanbaalenii_PYR-1       IRVDEDAAPGGRGHLWKLVRSFDDPGTWTEPGVRHLAAD-GIGGPMYRTD
MAB_4469c|M.abscessus_ATCC_199      VAVRTAEAKLANYSYWKPGGMRIDTSRPSEHEFYDYSTPSGKQESQNQAG
MAV_4858|M.avium_104                PLVTAPRPERELYDLRADPTEITNLLAGDDADADEVAAN--LAVLLHDWR
                                      *    .               :     :    . ::            

Mb3104|M.bovis_AF2122/97            PLDDQWELYDLTADPIEAYNRWTDPQLHELRQHLRMLLKQQRAVSVPERN
Rv3077|M.tuberculosis_H37Rv         PLDDQWELYDLTADPIEAYNRWTDPQLHELRQHLRMLLKQQRAVSVPERN
MMAR_1577|M.marinum_M               PVDDQWELYDLTADPIETDNRWTDPELHELRQHLRMQLKQQRASSVPERN
MUL_3457|M.ulcerans_Agy99           PVDDQWELYDLTADPIETDNRWTDPELHELRQHLRMQLKQQRASSVPERN
MSMEG_1286|M.smegmatis_MC2_155      PLDDQWELYDLTADPVEAVNRWHYPDLHEVRQYLLAQLKQVRASSVPERN
TH_0121|M.thermoresistible__bu      PLDDQWELYDLTVDPIEAVNRWDDPGLDELRRHLRAQLKQARTVSVPERN
Mflv_2372|M.gilvum_PYR-GCK          PLDDQWELYDLTDDPIEQTNRWPDPALHALRAYLRTQLKHARAQSIPERN
Mvan_4274|M.vanbaalenii_PYR-1       PLDDQWELYDLTDDPVEQHNRWTDPDLHELRAYLRAQLKSVRAESIPERN
MAB_4469c|M.abscessus_ATCC_199      DSTKQAQLQALIDN----------EVLPEVQAPLPAFLGQAQEQGLADMQ
MAV_4858|M.avium_104                QRTGDVIPSEFAGTRIAARYTETYLQIHHG-ARPTARSAIAADRGIEEEG
                                        :     :               :                 .: :  

Mb3104|M.bovis_AF2122/97            QPWPYAHRLPPSGASNGLVRRVLGRFVR
Rv3077|M.tuberculosis_H37Rv         QPWPYAHRLPPSGASNGLVRRVLGRFVR
MMAR_1577|M.marinum_M               QPWPYANRQPETGESQGPIRRLLGRIGS
MUL_3457|M.ulcerans_Agy99           QPWPYANRQPETGQSQGPIRRLLGRIGS
MSMEG_1286|M.smegmatis_MC2_155      VPWPYARR--------GGV---------
TH_0121|M.thermoresistible__bu      EPWPYVRRQAR-----------------
Mflv_2372|M.gilvum_PYR-GCK          QPWPYARRQPPPARRWTPGRALRRLLG-
Mvan_4274|M.vanbaalenii_PYR-1       RPWPYVRRQPPQPARWSPGRALRRLRD-
MAB_4469c|M.abscessus_ATCC_199      KLMVLRGG--------------------
MAV_4858|M.avium_104                NPAQR-----------------------