For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SEITVENLDAGYGSVQILHQVSMTARSGEVTCIFGPNGCGKSTLLKAIVGMIDPWAGTVKIDDEDITHLP SHKTLGRGVAMMPQGGGVFPHLSVRENLRIGGYTLRDKKELDQRIDTLLDEFPRLRERYTVAAGQLSGGE QMILSIARALVLNPRFLLFDEPSAGLSPKLVGDVLVRAAELAQRGVGVLMIEQNIREAMRVADRMYVLVG GRNRFDGTPADVADDRELMHLYLGGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1217 | - | - | 100% (237) | ABC-type transport system ATP-binding protein I |
| M. smegmatis MC2 155 | MSMEG_6876 | - | 1e-44 | 37.71% (236) | branched chain amino acid transport ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3251 | - | 1e-43 | 37.78% (225) | branched-chain amino acid ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-28 | 34.51% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3570 | - | 2e-44 | 38.22% (225) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-28 | 34.51% (226) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 1e-23 | 30.09% (226) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2622c | - | 4e-42 | 35.74% (235) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 1e-27 | 34.38% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 3e-28 | 35.40% (226) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_3858 | - | 3e-44 | 38.03% (234) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-27 | 34.38% (224) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | 6e-47 | 38.89% (234) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG-DFVALDHVDFVVPTGSLTAL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTAL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG-DFVALDHVDFVVPTGSLTAL
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLIL
Mflv_3570|M.gilvum_PYR-GCK -MTNS------PDPRPVLLEVRDAVVHYG-RIKALHSVSLTVHEGELVTL
Mvan_2845|M.vanbaalenii_PYR-1 -MSSPETVAGQPDPRPVLLEVRDVVVHYG-RIKALHSVSLTVHEGELVTL
TH_3858|M.thermoresistible__bu ----------------VMLEVRDVEVHYG-RIRALHGVSLRVHEGELVTL
MAB_2622c|M.abscessus_ATCC_199 -------------MPPVQLKLNNVGVHYG-PIQAVNTLSFDVREGELVTL
MSMEG_1217|M.smegmatis_MC2_155 ---------------MSEITVENLDAGYG-SVQILHQVSMTARSGEVTCI
: : . * :. :.: . *.. :
Mb2419c|M.bovis_AF2122/97 LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFVF
Rv2397c|M.tuberculosis_H37Rv LGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQR---RGIGFVF
MMAR_3715|M.marinum_M LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVF
MUL_3658|M.ulcerans_Agy99 LGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQR---RGIGFVF
MAV_1785|M.avium_104 LGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQR---RGIGFVF
MLBr_01089|M.leprae_Br4923 IGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKD---RDIAMVF
Mflv_3570|M.gilvum_PYR-GCK LGSNGAGKTTMMRAISGLLPLTSGSVWFEGKDISRVKAHKRVTDGLIQAP
Mvan_2845|M.vanbaalenii_PYR-1 LGSNGAGKTTMMRAISGLLPLSSGSVWFDGKDISRVKAHKRVADGLIQAP
TH_3858|M.thermoresistible__bu LGSNGAGKTTMMRAISGLRPLTRGSVWFDGRDITRVSAHRRVADGLIQVP
MAB_2622c|M.abscessus_ATCC_199 LGSNGAGKSTAMRAISGLVPLSSGTIFFEGQDISKMKAHRRVRAGIVQAP
MSMEG_1217|M.smegmatis_MC2_155 FGPNGCGKSTLLKAIVGMIDPWAGTVKIDDEDITHLPSHKTLGRGVAMMP
:*..*.**:* :. * *: * : : . :.. .: .:
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRKRPK-AEIKAKVDNLLQVVG-LSGFQSR
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRKRPK-AEIKAKVDNLLQVVG-LSGFQSR
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRKRPK-AEIRDKVDNLLEVVG-LSGFHGR
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRKRPK-AEIRDKVDNLLEVVG-LSGFHGR
MAV_1785|M.avium_104 QHYAAFKHLTVRDNVAYGLKVRKRPK-AEIKAKVDNLLEVVG-LSGFQGR
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFPLMLAKVKK-AEIAQKVSETAQILD-LTDLLDR
Mflv_3570|M.gilvum_PYR-GCK EGRGVFPGMTIIDNLEMGCYGRKFATNAEHDEKLDWVLETFPRLAERRSQ
Mvan_2845|M.vanbaalenii_PYR-1 EGRGVFPGMTIVENLEMGCYGRKFPSKAEHDERLDWVLETFPRLAERRNQ
TH_3858|M.thermoresistible__bu EGRGVFPGMTVLENLDMGCYGRRFASRAEHRERLDWVLQTFPRLAERRDQ
MAB_2622c|M.abscessus_ATCC_199 EGRGIFPGMTVAENLEMGCYGRKFKSRAERRERLDWINALFPRLAERRHQ
MSMEG_1217|M.smegmatis_MC2_155 QGGGVFPHLSVRENLRIGGY--TLRDKKELDQRIDTLLDEFPRLRERYTV
: . : ::: :*: * ::. . *
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MAV_1785|M.avium_104 YPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRL
MLBr_01089|M.leprae_Br4923 KPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARL
Mflv_3570|M.gilvum_PYR-GCK VGGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFKIIAEI
Mvan_2845|M.vanbaalenii_PYR-1 VGGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFRIIAEI
TH_3858|M.thermoresistible__bu VGGTLSGGEQQMLAIGRALMARPKVLLLDEPSMGLAPMVISQIFGIIADI
MAB_2622c|M.abscessus_ATCC_199 PGGTLSGGEQQMLSIGRALMARPKILLLDEPSMGLAPLLITKIFNIIEEI
MSMEG_1217|M.smegmatis_MC2_155 AAGQLSGGEQMILSIARALVLNPRFLLFDEPSAGLSPKLVGDVLVRAAEL
. ****:: :::.**: *. :*:*** * . : :
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
MAV_1785|M.avium_104 HDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAF
MLBr_01089|M.leprae_Br4923 QRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLF
Mflv_3570|M.gilvum_PYR-GCK N-ATGTTVLLVEQNAQQALSRSDRAYILETGEVTRTGNARELLAD--DSI
Mvan_2845|M.vanbaalenii_PYR-1 N-AAGTTVLLVEQNAQQALTRSDRAYILETGEVTRTGNARELLSD--KSI
TH_3858|M.thermoresistible__bu N-AQGTTVLLVEQNAQQALSRSDRAYILETGEITRSGPARELLAD--DSI
MAB_2622c|M.abscessus_ATCC_199 N-AAGTTVVLVEQNAQQALSRSDHAYILETGSVVRSGAGRELLQD--DSI
MSMEG_1217|M.smegmatis_MC2_155 A-QRGVGVLMIEQNIREAMRVADRMYVLVGGRNRFDGTPADVADD--REL
. .: : :: :*: .*: :: * * :: :
Mb2419c|M.bovis_AF2122/97 VMSFLG---------------------------AVSTLNGSLVRPHDIRV
Rv2397c|M.tuberculosis_H37Rv VMSFLG---------------------------AVSTLNGSLVRPHDIRV
MMAR_3715|M.marinum_M VMSFLG---------------------------AVSALNGALVRPHDIRV
MUL_3658|M.ulcerans_Agy99 VMSFLG---------------------------AVSALNGALVRPHDIRV
MAV_1785|M.avium_104 VMSFLG---------------------------AVSTLNGTLVRPHDIRV
MLBr_01089|M.leprae_Br4923 VAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIV
Mflv_3570|M.gilvum_PYR-GCK RAAYLG----------------------------VA--------------
Mvan_2845|M.vanbaalenii_PYR-1 RAAYLG----------------------------VA--------------
TH_3858|M.thermoresistible__bu RAAYLG----------------------------VA--------------
MAB_2622c|M.abscessus_ATCC_199 RSAYLG----------------------------VV--------------
MSMEG_1217|M.smegmatis_MC2_155 MHLYLG----------------------------GR--------------
::*
Mb2419c|M.bovis_AF2122/97 GRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGA
Rv2397c|M.tuberculosis_H37Rv GRTPNMAVAAADGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGA
MMAR_3715|M.marinum_M GRTPEMAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGA
MUL_3658|M.ulcerans_Agy99 GRTPEMAVAAADGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGA
MAV_1785|M.avium_104 GRTPEMAVAAEDGTAESTG---VARAIVDRVVKLGFEVRVELTSAATGGP
MLBr_01089|M.leprae_Br4923 GVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCD-V
Mflv_3570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2845|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3858|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1217|M.smegmatis_MC2_155 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 FTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVK
Rv2397c|M.tuberculosis_H37Rv FTAQITRGDAEALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVK
MMAR_3715|M.marinum_M FTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTP
MUL_3658|M.ulcerans_Agy99 FTAQITRGDAEALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTP
MAV_1785|M.avium_104 FTAQITRGDAEALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEAT
MLBr_01089|M.leprae_Br4923 YSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDAD
Mflv_3570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2845|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3858|M.thermoresistible__bu --------------------------------------------------
MAB_2622c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_1217|M.smegmatis_MC2_155 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 VTST---------
Rv2397c|M.tuberculosis_H37Rv VTST---------
MMAR_3715|M.marinum_M SAAQIGVGGQ---
MUL_3658|M.ulcerans_Agy99 RAAQIGVGGQ---
MAV_1785|M.avium_104 LTSA---------
MLBr_01089|M.leprae_Br4923 SGVNLTVSAPTDA
Mflv_3570|M.gilvum_PYR-GCK -------------
Mvan_2845|M.vanbaalenii_PYR-1 -------------
TH_3858|M.thermoresistible__bu -------------
MAB_2622c|M.abscessus_ATCC_199 -------------
MSMEG_1217|M.smegmatis_MC2_155 -------------