For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MQIAVVLYPTFTALDFIGPYEVLRNLPDAEVRFVWHEPGPVTADSGVLMVGATHTFDETPSPDVVLVPGG PGSSAAARDERVLAWLRAVHPTANWVASVCSGSMVLAAAGLLDGKRATSHWGALSALKMCGVTAVSDERI VRADDKVITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQPPFDAGHMSKASATTKAGATALLGR DMIKPEPLKASVLLAWDQAIRRVRGRGAARRTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1107 | - | - | 100% (243) | isonitrile hydratase, putative |
| M. smegmatis MC2 155 | MSMEG_3366 | - | 4e-42 | 44.02% (209) | isonitrile hydratase, putative |
| M. smegmatis MC2 155 | MSMEG_3365 | - | 3e-19 | 33.16% (187) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1965c | - | 1e-41 | 63.08% (130) | hypothetical protein Mb1965c |
| M. gilvum PYR-GCK | Mflv_5266 | - | 3e-96 | 70.51% (234) | ThiJ/PfpI domain-containing protein |
| M. tuberculosis H37Rv | Rv1930c | - | 1e-41 | 63.08% (130) | hypothetical protein Rv1930c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0943 | - | 1e-97 | 71.49% (242) | hypothetical protein MAB_0943 |
| M. marinum M | MMAR_2854 | - | 3e-90 | 65.42% (240) | hypothetical protein MMAR_2854 |
| M. avium 104 | MAV_2773 | - | 1e-95 | 69.17% (240) | DJ-1/PfpI family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 6e-11 | 33.57% (143) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_0070 | - | 5e-52 | 46.63% (208) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0973 | - | 2e-97 | 70.34% (236) | ThiJ/PfpI domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5266|M.gilvum_PYR-GCK -----MQVAIMLYPGFTALDFIGPYESLRWLPDTEVRFVWHEPGPIAADS
Mvan_0973|M.vanbaalenii_PYR-1 -----MQVAIMLYPGFTALDFIGPYESLRWLPDVEVRFVWHEPGPIAADS
Mb1965c|M.bovis_AF2122/97 ----MTQIAFVAYPGVTALDVVGPYEVLRNLPHAQVRFVW----------
Rv1930c|M.tuberculosis_H37Rv ----MTQIAFVAYPGVTALDVVGPYEVLRNLPHAQVRFVW----------
MMAR_2854|M.marinum_M ----MPQFAFVAYPGFTALDMIGPYEVLRNLPHAEVRFVWHDPGPITADS
MAV_2773|M.avium_104 ----MTQIAFLAYPGFTALDMIGPYEVLRNLPGAEVRFVWHETGPITADS
MSMEG_1107|M.smegmatis_MC2_155 -----MQIAVVLYPTFTALDFIGPYEVLRNLPDAEVRFVWHEPGPVTADS
MAB_0943|M.abscessus_ATCC_1997 MTSAATQIAIVLYPDFTALDFIGPYEVLRFIPDTEVRFVWHEPGPVTADS
MUL_0070|M.ulcerans_Agy99 -----MQVAIPVFPRFTALDAVGPYEVLQRIPSIDVVFIGHQRGEVRTEN
TH_3120|M.thermoresistible__bu -VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAGQPVRTS
.. : . : .* . :* :. .
Mflv_5266|M.gilvum_PYR-GCK HVLLVGATHSFDETPSPDVILIPGGFATMEHARDEVVLAWVRRAHETSTW
Mvan_0973|M.vanbaalenii_PYR-1 HVLLVGATHSFDETPSPDLILIPGGFATMEHARDEKVLDWVRRAHRTSTW
Mb1965c|M.bovis_AF2122/97 --------------------------------------------------
Rv1930c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2854|M.marinum_M GVLVLGATHSLAETPAPDVVVVPGGPATPVHARDEKLLDWLRQAHRSASW
MAV_2773|M.avium_104 GVLVIGATHSLAETPSPDVVLVPGGPGTAVHARDDALLDWLRTAHRTATW
MSMEG_1107|M.smegmatis_MC2_155 GVLMVGATHTFDETPSPDVVLVPGGPGSSAAARDERVLAWLRAVHPTANW
MAB_0943|M.abscessus_ATCC_1997 GVLVIGATHSFGETPAPDVVLVPGGPGTTMAARDDKLLDWLRRVHPAAAW
MUL_0070|M.ulcerans_Agy99 GMLGVTCDATFDEVDAPDVVAFPGGIGTRGLLEDETIRGWLQAVHPHTRF
TH_3120|M.thermoresistible__bu FGATLTPDSGLDGLAGADLVAIP---AIRQDDYLPEALDAVRAAADAGAI
Mflv_5266|M.gilvum_PYR-GCK TTSVCSGSVILAAAGVLDGKRATSHWAALPVLKTLGAQPVGDQRIVEA-D
Mvan_0973|M.vanbaalenii_PYR-1 TTSVCSGSVILAASGVLDGKRATSHWAALPVLKTFGVQPVGDERVVVA-D
Mb1965c|M.bovis_AF2122/97 ----------------LRGRRATSHWLTLPALKAFGAIPVADERIVH--Q
Rv1930c|M.tuberculosis_H37Rv ----------------LRGRRATSHWLTLPALKAFGAIPVADERIVH--Q
MMAR_2854|M.marinum_M TTSVCSGSVILAAAGLLKDRRATSHWLTIPALKAFGAIPVADKRIVQ--Q
MAV_2773|M.avium_104 TTSVCTGSLILAAAGLLDGRRATSHWLTIPALKAFGVTAVPDERIVH--E
MSMEG_1107|M.smegmatis_MC2_155 VASVCSGSMVLAAAGLLDGKRATSHWGALSALKMCGVTAVSDERIVRADD
MAB_0943|M.abscessus_ATCC_1997 TTSVCSGSLVLAAAGLLEGQRATSHWSTLPLLKPFGVTPVGDERIVRTGH
MUL_0070|M.ulcerans_Agy99 TTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVP-QRVVEHLP
TH_3120|M.thermoresistible__bu ILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVLYVDD
* . .*:** * ..::
Mflv_5266|M.gilvum_PYR-GCK AKTVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQ---------
Mvan_0973|M.vanbaalenii_PYR-1 DKTVTAAGVSAGIDLGLWLAGQIAGESKAKAIQLSMEYDPQ---------
Mb1965c|M.bovis_AF2122/97 DNIVTSAGVSAGLDLALWLAGQLGGEARAKAIQLAIEYDPQ---------
Rv1930c|M.tuberculosis_H37Rv DNIVTSAGVSAGLDLALWLAGQLGGEARAKAIQLAIEYDPQ---------
MMAR_2854|M.marinum_M DNIITSAGVSAGLDLGLWLAGQIGGESRAKAIQLALEYDPQ---------
MAV_2773|M.avium_104 DGIVTSAGVSAGLDLALWLAAQIGGDGRAKAIQLALEYDPQ---------
MSMEG_1107|M.smegmatis_MC2_155 K-VITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQ---------
MAB_0943|M.abscessus_ATCC_1997 AGLVTAAGVSAGIDLGLWLAGQIAGEERAKAIQLSIEYDPQ---------
MUL_0070|M.ulcerans_Agy99 QRIITAAGVSSGIDMGLRLVELLVDREAAQVTQLLIEYDPE---------
TH_3120|M.thermoresistible__bu GDLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGGQRQFI
:*:**.::*:* : *. . ::. : *:
Mflv_5266|M.gilvum_PYR-GCK -PPFDSGHMS------------------------KASAGTKALATAMMGR
Mvan_0973|M.vanbaalenii_PYR-1 -PPFDSGHMS------------------------KASASTKALATAMMGR
Mb1965c|M.bovis_AF2122/97 -PPFDSGHMS------------------------KASPTTKAAATALLSK
Rv1930c|M.tuberculosis_H37Rv -PPFDSGHMS------------------------KASPTTKAAATALLSK
MMAR_2854|M.marinum_M -PPFDSGHMS------------------------KASASTKVAATALLSK
MAV_2773|M.avium_104 -PPFDSGHLS------------------------KASASTKAAATALLSR
MSMEG_1107|M.smegmatis_MC2_155 -PPFDAGHMS------------------------KASATTKAGATALLGR
MAB_0943|M.abscessus_ATCC_1997 -PPFDSGHMS------------------------KASAATKATATAGLAK
MUL_0070|M.ulcerans_Agy99 -PPFDAGSLA------------------------KADEGVRARAIEFLDS
TH_3120|M.thermoresistible__bu DQPIPVRHSEGFAPHLDWILSNLDKTHTVASLARRANMSPRTFARRFVEE
*: :*. :. * :
Mflv_5266|M.gilvum_PYR-GCK EMVRPAALAASTGLLWDAALKRIRRAKRRQ--GSLSAP------------
Mvan_0973|M.vanbaalenii_PYR-1 EMAKPAALAASTGLLWDAALKRIRARRSRPEPAKLRGGS-----------
Mb1965c|M.bovis_AF2122/97 DSAKPANLTAATLLAWERALAAVQSRRRKRQPVGAQARRP----------
Rv1930c|M.tuberculosis_H37Rv DSAKPANLTAATLLAWERALAAVQSRRRKRQPVGAQARRP----------
MMAR_2854|M.marinum_M DSATPVNLKAATMLAWQQALAAARARRRKRQPVDSTP-------------
MAV_2773|M.avium_104 DSLSPTYLKATALLAWDQALDRVRSRRRRRQPDLSPA-------------
MSMEG_1107|M.smegmatis_MC2_155 DMIKPEPLKASVLLAWDQAIRRVRGRGAARRTA-----------------
MAB_0943|M.abscessus_ATCC_1997 DTFKPSVMAAGAKLLWDGALATARRRGDRRRSFGSRLDPRARP-------
MUL_0070|M.ulcerans_Agy99 RK------------------------------------------------
TH_3120|M.thermoresistible__bu TGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLLRHHFRRV
Mflv_5266|M.gilvum_PYR-GCK ------------------------------
Mvan_0973|M.vanbaalenii_PYR-1 ------------------------------
Mb1965c|M.bovis_AF2122/97 ------------------------------
Rv1930c|M.tuberculosis_H37Rv ------------------------------
MMAR_2854|M.marinum_M ------------------------------
MAV_2773|M.avium_104 ------------------------------
MSMEG_1107|M.smegmatis_MC2_155 ------------------------------
MAB_0943|M.abscessus_ATCC_1997 ------------------------------
MUL_0070|M.ulcerans_Agy99 ------------------------------
TH_3120|M.thermoresistible__bu IGVTPSDYRRRFACGSTTSGSTESGAEVTD