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QVAIMLYPGFTALDFIGPYESLRWLPDTEVRFVWHEPGPIAADSHVLLVGATHSFDETPSPDVILIPGGF ATMEHARDEVVLAWVRRAHETSTWTTSVCSGSVILAAAGVLDGKRATSHWAALPVLKTLGAQPVGDQRIV EADAKTVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQPPFDSGHMSKASAGTKALATAMMGRE MVRPAALAASTGLLWDAALKRIRRAKRRQGSLSAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5266 | - | - | 100% (246) | ThiJ/PfpI domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5267 | - | 7e-17 | 32.12% (193) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1437 | - | 4e-14 | 27.89% (190) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1965c | - | 2e-40 | 58.21% (134) | hypothetical protein Mb1965c |
| M. tuberculosis H37Rv | Rv1930c | - | 2e-40 | 58.21% (134) | hypothetical protein Rv1930c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0943 | - | 3e-95 | 67.35% (245) | hypothetical protein MAB_0943 |
| M. marinum M | MMAR_2854 | - | 4e-88 | 63.82% (246) | hypothetical protein MMAR_2854 |
| M. avium 104 | MAV_2773 | - | 2e-89 | 64.75% (244) | DJ-1/PfpI family protein |
| M. smegmatis MC2 155 | MSMEG_1107 | - | 3e-96 | 70.51% (234) | isonitrile hydratase, putative |
| M. thermoresistible (build 8) | TH_3120 | - | 1e-09 | 34.65% (101) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_0070 | - | 1e-48 | 44.61% (204) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0973 | - | 1e-125 | 90.79% (239) | ThiJ/PfpI domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5266|M.gilvum_PYR-GCK -----MQVAIMLYPGFTALDFIGPYESLRWLPDTEVRFVWHEPGPIAADS
Mvan_0973|M.vanbaalenii_PYR-1 -----MQVAIMLYPGFTALDFIGPYESLRWLPDVEVRFVWHEPGPIAADS
MAB_0943|M.abscessus_ATCC_1997 MTSAATQIAIVLYPDFTALDFIGPYEVLRFIPDTEVRFVWHEPGPVTADS
MSMEG_1107|M.smegmatis_MC2_155 -----MQIAVVLYPTFTALDFIGPYEVLRNLPDAEVRFVWHEPGPVTADS
Mb1965c|M.bovis_AF2122/97 ----MTQIAFVAYPGVTALDVVGPYEVLRNLPHAQVRFVW----------
Rv1930c|M.tuberculosis_H37Rv ----MTQIAFVAYPGVTALDVVGPYEVLRNLPHAQVRFVW----------
MMAR_2854|M.marinum_M ----MPQFAFVAYPGFTALDMIGPYEVLRNLPHAEVRFVWHDPGPITADS
MAV_2773|M.avium_104 ----MTQIAFLAYPGFTALDMIGPYEVLRNLPGAEVRFVWHETGPITADS
MUL_0070|M.ulcerans_Agy99 -----MQVAIPVFPRFTALDAVGPYEVLQRIPSIDVVFIGHQRGEVRTEN
TH_3120|M.thermoresistible__bu -VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAGQPVRTS
.. : . : .* . :* :. .
Mflv_5266|M.gilvum_PYR-GCK HVLLVGATHSFDETPSPDVILIPGGFATMEHARDEVVLAWVRRAHETSTW
Mvan_0973|M.vanbaalenii_PYR-1 HVLLVGATHSFDETPSPDLILIPGGFATMEHARDEKVLDWVRRAHRTSTW
MAB_0943|M.abscessus_ATCC_1997 GVLVIGATHSFGETPAPDVVLVPGGPGTTMAARDDKLLDWLRRVHPAAAW
MSMEG_1107|M.smegmatis_MC2_155 GVLMVGATHTFDETPSPDVVLVPGGPGSSAAARDERVLAWLRAVHPTANW
Mb1965c|M.bovis_AF2122/97 --------------------------------------------------
Rv1930c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2854|M.marinum_M GVLVLGATHSLAETPAPDVVVVPGGPATPVHARDEKLLDWLRQAHRSASW
MAV_2773|M.avium_104 GVLVIGATHSLAETPSPDVVLVPGGPGTAVHARDDALLDWLRTAHRTATW
MUL_0070|M.ulcerans_Agy99 GMLGVTCDATFDEVDAPDVVAFPGGIGTRGLLEDETIRGWLQAVHPHTRF
TH_3120|M.thermoresistible__bu FGATLTPDSGLDGLAGADLVAIP---AIRQDDYLPEALDAVRAAADAGAI
Mflv_5266|M.gilvum_PYR-GCK TTSVCSGSVILAAAGVLDGKRATSHWAALPVLKTLGAQPVGDQRIVEA-D
Mvan_0973|M.vanbaalenii_PYR-1 TTSVCSGSVILAASGVLDGKRATSHWAALPVLKTFGVQPVGDERVVVA-D
MAB_0943|M.abscessus_ATCC_1997 TTSVCSGSLVLAAAGLLEGQRATSHWSTLPLLKPFGVTPVGDERIVRTGH
MSMEG_1107|M.smegmatis_MC2_155 VASVCSGSMVLAAAGLLDGKRATSHWGALSALKMCGVTAVSDERIVRADD
Mb1965c|M.bovis_AF2122/97 ----------------LRGRRATSHWLTLPALKAFGAIPVADERIVH--Q
Rv1930c|M.tuberculosis_H37Rv ----------------LRGRRATSHWLTLPALKAFGAIPVADERIVH--Q
MMAR_2854|M.marinum_M TTSVCSGSVILAAAGLLKDRRATSHWLTIPALKAFGAIPVADKRIVQ--Q
MAV_2773|M.avium_104 TTSVCTGSLILAAAGLLDGRRATSHWLTIPALKAFGVTAVPDERIVH--E
MUL_0070|M.ulcerans_Agy99 TTSVCTGALLLAAAGLLDGLTATTHWRAAELLNGLGARYVP-QRVVEHLP
TH_3120|M.thermoresistible__bu ILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVLYVDD
* . .*:** * ..::
Mflv_5266|M.gilvum_PYR-GCK AKTVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQ---------
Mvan_0973|M.vanbaalenii_PYR-1 DKTVTAAGVSAGIDLGLWLAGQIAGESKAKAIQLSMEYDPQ---------
MAB_0943|M.abscessus_ATCC_1997 AGLVTAAGVSAGIDLGLWLAGQIAGEERAKAIQLSIEYDPQ---------
MSMEG_1107|M.smegmatis_MC2_155 K-VITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQ---------
Mb1965c|M.bovis_AF2122/97 DNIVTSAGVSAGLDLALWLAGQLGGEARAKAIQLAIEYDPQ---------
Rv1930c|M.tuberculosis_H37Rv DNIVTSAGVSAGLDLALWLAGQLGGEARAKAIQLAIEYDPQ---------
MMAR_2854|M.marinum_M DNIITSAGVSAGLDLGLWLAGQIGGESRAKAIQLALEYDPQ---------
MAV_2773|M.avium_104 DGIVTSAGVSAGLDLALWLAAQIGGDGRAKAIQLALEYDPQ---------
MUL_0070|M.ulcerans_Agy99 QRIITAAGVSSGIDMGLRLVELLVDREAAQVTQLLIEYDPE---------
TH_3120|M.thermoresistible__bu GDLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGGQRQFI
:*:**.::*:* : *. . ::. : *:
Mflv_5266|M.gilvum_PYR-GCK -PPFDSGHMS------------------------KASAGTKALATAMMGR
Mvan_0973|M.vanbaalenii_PYR-1 -PPFDSGHMS------------------------KASASTKALATAMMGR
MAB_0943|M.abscessus_ATCC_1997 -PPFDSGHMS------------------------KASAATKATATAGLAK
MSMEG_1107|M.smegmatis_MC2_155 -PPFDAGHMS------------------------KASATTKAGATALLGR
Mb1965c|M.bovis_AF2122/97 -PPFDSGHMS------------------------KASPTTKAAATALLSK
Rv1930c|M.tuberculosis_H37Rv -PPFDSGHMS------------------------KASPTTKAAATALLSK
MMAR_2854|M.marinum_M -PPFDSGHMS------------------------KASASTKVAATALLSK
MAV_2773|M.avium_104 -PPFDSGHLS------------------------KASASTKAAATALLSR
MUL_0070|M.ulcerans_Agy99 -PPFDAGSLA------------------------KADEGVRARAIEFLDS
TH_3120|M.thermoresistible__bu DQPIPVRHSEGFAPHLDWILSNLDKTHTVASLARRANMSPRTFARRFVEE
*: :*. :. * :
Mflv_5266|M.gilvum_PYR-GCK EMVRPAALAASTGLLWDAALKRIRRAKRRQ--GSLSAP------------
Mvan_0973|M.vanbaalenii_PYR-1 EMAKPAALAASTGLLWDAALKRIRARRSRPEPAKLRGGS-----------
MAB_0943|M.abscessus_ATCC_1997 DTFKPSVMAAGAKLLWDGALATARRRGDRRRSFGSRLDPRARP-------
MSMEG_1107|M.smegmatis_MC2_155 DMIKPEPLKASVLLAWDQAIRRVRGRGAARRTA-----------------
Mb1965c|M.bovis_AF2122/97 DSAKPANLTAATLLAWERALAAVQSRRRKRQPVGAQARRP----------
Rv1930c|M.tuberculosis_H37Rv DSAKPANLTAATLLAWERALAAVQSRRRKRQPVGAQARRP----------
MMAR_2854|M.marinum_M DSATPVNLKAATMLAWQQALAAARARRRKRQPVDSTP-------------
MAV_2773|M.avium_104 DSLSPTYLKATALLAWDQALDRVRSRRRRRQPDLSPA-------------
MUL_0070|M.ulcerans_Agy99 RK------------------------------------------------
TH_3120|M.thermoresistible__bu TGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLLRHHFRRV
Mflv_5266|M.gilvum_PYR-GCK ------------------------------
Mvan_0973|M.vanbaalenii_PYR-1 ------------------------------
MAB_0943|M.abscessus_ATCC_1997 ------------------------------
MSMEG_1107|M.smegmatis_MC2_155 ------------------------------
Mb1965c|M.bovis_AF2122/97 ------------------------------
Rv1930c|M.tuberculosis_H37Rv ------------------------------
MMAR_2854|M.marinum_M ------------------------------
MAV_2773|M.avium_104 ------------------------------
MUL_0070|M.ulcerans_Agy99 ------------------------------
TH_3120|M.thermoresistible__bu IGVTPSDYRRRFACGSTTSGSTESGAEVTD