For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MEPFIGSAAVSSGALTRRGLQRHYTALYRDVYIPRDLEVTARIRAEAAWLATRAPLAGTSAAAVLGTRWL RPELPAQIIRADRHAPPGIVAHSWTLAPGETCLVAGMDATTPARTAFDLGRLHRAGDAVPLVDALLNATG IKPADVLAVADAHPGARGVARLRVLLPLLDGGAESPQESRLRLVLVRGGLPVPQTQIEFRDLRIRVDMGW PEWKVAVEYDGVQHWSDRRQRSWDIDRIALLEEAGWVVVRVSAEMLSRPHVVVERVRAKLRAAGCPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0881 | - | - | 100% (277) | hypothetical protein MSMEG_0881 |
| M. smegmatis MC2 155 | MSMEG_5314 | - | 6e-75 | 53.21% (280) | hypothetical protein MSMEG_5314 |
| M. smegmatis MC2 155 | MSMEG_0914 | - | 1e-70 | 52.17% (276) | hypothetical protein MSMEG_0914 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3585c | - | 6e-69 | 49.64% (280) | hypothetical protein Mb3585c |
| M. gilvum PYR-GCK | Mflv_1289 | - | 1e-55 | 45.32% (278) | hypothetical protein Mflv_1289 |
| M. tuberculosis H37Rv | Rv3555c | - | 8e-69 | 49.64% (280) | hypothetical protein Rv3555c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4161 | - | 6e-62 | 46.76% (278) | hypothetical protein MAB_4161 |
| M. marinum M | MMAR_4658 | - | 6e-60 | 46.91% (275) | hypothetical protein MMAR_4658 |
| M. avium 104 | MAV_4706 | - | 2e-97 | 64.23% (274) | hypothetical protein MAV_4706 |
| M. thermoresistible (build 8) | TH_3487 | - | 3e-69 | 48.40% (281) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 9e-57 | 44.57% (276) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_5044 | - | 2e-65 | 47.18% (284) | hypothetical protein Mvan_5044 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0881|M.smegmatis_MC2_155 --------ME-------PFIGSAAVSSGALTRRGLQRHYTALYRDVYIPR
MAV_4706|M.avium_104 MCGGEYAGMS-------PFLGSDALHRGAVTRSQLRTRYRKVFRDVYIAK
MMAR_4658|M.marinum_M ----MEILDW-------PFRGTEALAAGAVTPHRLRTHFEMVHRNVYIPR
Mvan_5044|M.vanbaalenii_PYR-1 ----MD-----------PFLGTEALAAGSLTRYRLKTRFELVHRNVYALN
Mb3585c|M.bovis_AF2122/97 ----MDELPW-------PVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPA
Rv3555c|M.tuberculosis_H37Rv ----MDELPW-------PVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPA
MAB_4161|M.abscessus_ATCC_1997 ----MGDVPW-------PLIRSEALTNRVVTGYALRQ-FTALYPGIYAPT
TH_3487|M.thermoresistible__bu ----MAEG---------PFLGSEARAAGLVTRRTLRSRHRLIYQNVYLPV
Mflv_1289|M.gilvum_PYR-GCK ----MTAMDR-------VILGGEAVRAGVATRHELARDYTRLYRGVFVRN
MUL_4737|M.ulcerans_Agy99 ----MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLPA
. . . : . :. .::
MSMEG_0881|M.smegmatis_MC2_155 DLEVTARIRAEAAWLATR--APLAGTSAAAVLGTRWLRPELPAQIIRADR
MAV_4706|M.avium_104 DAELTPAGKARAAWLSTG--ATLAGLSAAAIHGTKWLDAAAPAEIVRADR
MMAR_4658|M.marinum_M GKKLTAVTRAIAAWLWSGRSATAVGLSAAALHRTGWIDDWLPAELNRRGR
Mvan_5044|M.vanbaalenii_PYR-1 REQLTPVQKARAAWLWSGRRGTLVGLSAAAVLGSRWIDARLPAELNQRSQ
Mb3585c|M.bovis_AF2122/97 GVELTARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANR
Rv3555c|M.tuberculosis_H37Rv GVELTARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANR
MAB_4161|M.abscessus_ATCC_1997 DAQITPRKRAEAAWLWSRRKGTIAGISAAALHGTKWLPQQGPVVLIHTNR
TH_3487|M.thermoresistible__bu GVQLTAQTRAVAAWLWARRDATVAGLSAAALHGTKWIDPALPAELIRPSP
Mflv_1289|M.gilvum_PYR-GCK GIEITLRDRAIGAWLATGRKGVISGRTAAALHGAPLVDLTIPIELTGAKG
MUL_4737|M.ulcerans_Agy99 HAAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRNP
: :. .*** : . * :**.: : : :
MSMEG_0881|M.smegmatis_MC2_155 HAPPGIVAHSWTLAPGETCLVAGMDATTPARTAFDLGRLHRAGD-AVPLV
MAV_4706|M.avium_104 HGQRGILVRSYTLADDEADTVSGMRVTTAARTAFDIGCGLPAAK-ALPIL
MMAR_4658|M.marinum_M DKARGIISHSACLDEDEVCVRDGIALTTPARTAFDLGRRKGLTT-AVIRL
Mvan_5044|M.vanbaalenii_PYR-1 HKTPGIVLRADTLGPDEIVTARGMPVTSPARTAFDLGRRRGLTL-AVIRM
Mb3585c|M.bovis_AF2122/97 KPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRL
Rv3555c|M.tuberculosis_H37Rv KPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRL
MAB_4161|M.abscessus_ATCC_1997 RAPRGITLWSDSLPEGERMFVDGLPVTTPARTAFDIGRRTPVDL-AVQHL
TH_3487|M.thermoresistible__bu GSPDGIVIHRDRLEPGEVCTLRGIPVTTPARTAYDIGRRQTLTR-AVVRL
Mflv_1289|M.gilvum_PYR-GCK RSQEGLILRNESLAPDEVTRRSGLPVSTRVRTAFDLGRHLERPE-ALARL
MUL_4737|M.ulcerans_Agy99 HPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGE-SVARL
: : * *: :: .***:*:* :: :
MSMEG_0881|M.smegmatis_MC2_155 DALLNATGIKPADVLAVADAHPGARGVARLRVLLPLLDGGAESPQESRLR
MAV_4706|M.avium_104 DALLNATGIKPADVVAVADRHRGARGIRRLRASLELADGGAESPQETRLR
MMAR_4658|M.marinum_M DALTRATELKVADVEMLAERHRGARGLIQLRQALPLVDAGADSPYETRIR
Mvan_5044|M.vanbaalenii_PYR-1 DALMRTTGATTSDIATLLTRHKGARGLVQLRRALELVDPASESPQESRTR
Mb3585c|M.bovis_AF2122/97 DALANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTR
Rv3555c|M.tuberculosis_H37Rv DALANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTR
MAB_4161|M.abscessus_ATCC_1997 DALMNATRLSRTDIETVATHHRGARGLHHLANVLGLVDGGAESPWETRTR
TH_3487|M.thermoresistible__bu DALANATGLTADAVTAVIDRRRGARGLVRLRRAVGLMDGGAASPPETRTR
Mflv_1289|M.gilvum_PYR-GCK DALMWNQRYAIDDVLALAERHPRARGVTQLRELLPLVDGGAASPRESALR
MUL_4737|M.ulcerans_Agy99 DALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLR
*** : : ***: :* : * * .: ** *: *
MSMEG_0881|M.smegmatis_MC2_155 LVLVRGGLPVPQTQIEFR----DLRIRVDMGWPEWKVAVEYDGVQHWSDR
MAV_4706|M.avium_104 VLLVRAGLPKPQTQIELR----ELRVRVDMGWREWKVAVEYDGIQHWDDP
MMAR_4658|M.marinum_M LLVIRSGLPAPQTEIKVLDDWGAVAARIGMGWPECKVGVEFDSAGQWNNA
Mvan_5044|M.vanbaalenii_PYR-1 LLLVKAGLPPERSQIDVFDRDGYHVGRVDMGWETWKVGVEYEGEQHWTNP
Mb3585c|M.bovis_AF2122/97 LVLIDAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDP
Rv3555c|M.tuberculosis_H37Rv LVLIDAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDP
MAB_4161|M.abscessus_ATCC_1997 LLVVRAGFPAPQTQLVVRNRFGDFVARLDMGWPDHKVGIEFDGAQHWTSA
TH_3487|M.thermoresistible__bu LLLLAAGFPRPRTQVVVCDPFGYFIGRIDIGWPEYRVGVEYDGAWHWADA
Mflv_1289|M.gilvum_PYR-GCK LALIDSGFPKPETQIPVFAG-TRPIAFLDMGWEEYGVAVEYDGDHHRKDR
MUL_4737|M.ulcerans_Agy99 MVLIDAGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFDR
: :: .*:* ::: . :.:*: *. *::. : .
MSMEG_0881|M.smegmatis_MC2_155 RQRSWDIDRIALLEEAGWVVVRVSAEMLS-RPHVVVERVRAKLRAAGCPI
MAV_4706|M.avium_104 SQRAWDIERIALLEAAGWAVIRVSAAMLS-RPQVIVERVTAKLAERGAYG
MMAR_4658|M.marinum_M AR-SDAVDRSAELEARGWTIVRVNAQTLKNRPDIVVAQVRHALVRRT---
Mvan_5044|M.vanbaalenii_PYR-1 EQYAHDIDRQAALEAEGWRIIRVSAEILRDRPTTIVSRVWLALRAAGAPV
Mb3585c|M.bovis_AF2122/97 AQRARDIERSTALLDLGWTIIRVTSELLRYRRGTFVGRVDAAMRAAGWRP
Rv3555c|M.tuberculosis_H37Rv AQRARDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVDAAMRAAGWRP
MAB_4161|M.abscessus_ATCC_1997 QQRTRDIDRATELVDEGWRIIRVSSDMVRHRSGTILARVAEAFVAARAA-
TH_3487|M.thermoresistible__bu AAHAQTIDRVADLEEQGWIIIRISRDILRYRPGVFLARVRNALRAHGWPD
Mflv_1289|M.gilvum_PYR-GCK RQYVKDIARLRMLEERGWSVVRV---IAEDMPAAWLRRVADALRRKGCPL
MUL_4737|M.ulcerans_Agy99 RQYAREQWRLRKLDELGWIVIRV---IAGDAPEDVVRRVRQALARRGHRE
* * ** ::*: : :* :
MSMEG_0881|M.smegmatis_MC2_155 ------------
MAV_4706|M.avium_104 RPRASSRA----
MMAR_4658|M.marinum_M ------------
Mvan_5044|M.vanbaalenii_PYR-1 QPPNLNL-----
Mb3585c|M.bovis_AF2122/97 ------------
Rv3555c|M.tuberculosis_H37Rv ------------
MAB_4161|M.abscessus_ATCC_1997 ------------
TH_3487|M.thermoresistible__bu HASVRLDARLEP
Mflv_1289|M.gilvum_PYR-GCK AWVAGKTIAA--
MUL_4737|M.ulcerans_Agy99 T-----------