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MTEQPPPGGSYPPPPPPPGPSGGHEPPPAAPPGGSGYAPPPPPSSGSGYPPPPPPPGGGAYPPPPPSAGG YAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIGWVIMLVTQTSSCVTSISEYDVGQFCVSQ PSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFGMSVVRQLAHFIDAI ICFVGFLFPLWDAKRQTLADKIMTTVCVPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1078 | pra | - | 100% (240) | Probable Proline-rich antigen homolog pra |
| M. tuberculosis H37Rv | Rv1233c | - | 1e-12 | 46.07% (89) | hypothetical protein Rv1233c |
| M. tuberculosis H37Rv | Rv3494c | mce4F | 2e-12 | 45.05% (91) | MCE-family protein MCE4F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1107 | pra | 1e-147 | 99.58% (240) | proline-rich antigen |
| M. gilvum PYR-GCK | Mflv_2045 | - | 6e-34 | 45.06% (162) | RDD domain-containing protein |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-98 | 65.61% (253) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_1196 | - | 2e-44 | 49.74% (195) | proline-rich antigen |
| M. marinum M | MMAR_4389 | pra | 1e-119 | 74.53% (267) | proline-rich antigen, Pra |
| M. avium 104 | MAV_1202 | - | 1e-101 | 67.92% (240) | Pra protein |
| M. smegmatis MC2 155 | MSMEG_5266 | - | 9e-51 | 48.48% (231) | RDD family protein |
| M. thermoresistible (build 8) | TH_3105 | - | 1e-08 | 37.80% (82) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0202 | pra | 1e-119 | 77.38% (252) | proline-rich antigen Pra-like protein |
| M. vanbaalenii PYR-1 | Mvan_4672 | - | 4e-40 | 49.12% (171) | RDD domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1078|M.tuberculosis_H37Rv MTEQPPPGGSYP-PPPPPPGPSGGHEP------------PPAAPPGGSGY
Mb1107|M.bovis_AF2122/97 MTEQPPPGGSYP-PPPPPPGPSGGHEP------------PPAAPPGGSGY
MMAR_4389|M.marinum_M MTDQPPPGGSYP-PPPPPPGSSGGSEPPAGGYQA----PPPPSAPSGGGY
MUL_0202|M.ulcerans_Agy99 MTDQPPPGGSYP-PPPPPPGSSGGSEPPAGGYQA----PPPPSAPSGGGY
MAV_1202|M.avium_104 MTDQPPPGGAYP-PPPSSPGSPGGQPT------------PPPG-----GQ
MLBr_02395|M.leprae_Br4923 MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSY
Mflv_2045|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4672|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5266|M.smegmatis_MC2_155 MTQLPPQG-----PGPAPYGPHPG------------------------GH
MAB_1196|M.abscessus_ATCC_1997 MTEVP---------------------------------------------
TH_3105|M.thermoresistible__bu MTNPGNADGTPPAEGQPGPSETGADDLAR---------EPTGGADPTASE
Rv1078|M.tuberculosis_H37Rv APPPPPS--SGSGYPPPPPPP-----------------GGGAYPPPPPSA
Mb1107|M.bovis_AF2122/97 APPPPPS--SGSGYPPPPPPP-----------------GGGAYPPPPPSA
MMAR_4389|M.marinum_M PPPPPPPSPSTSGYPPPPPPPSAPGGSAYPPPPPPPPLEGGYPPPPPPSA
MUL_0202|M.ulcerans_Agy99 PPPPPPPPPSTSGYPPPPPPP---------------PLEGGYPPPPPPSA
MAV_1202|M.avium_104 QPPPPPG-----GSYPPPPPP------------------GGSYPPPPPPS
MLBr_02395|M.leprae_Br4923 PPPPPPG-----GSYPPPPPP------------------GGSYPPPPPST
Mflv_2045|M.gilvum_PYR-GCK ------------------------------------------------MR
Mvan_4672|M.vanbaalenii_PYR-1 ------------------------------------------------MT
MSMEG_5266|M.smegmatis_MC2_155 PGP--------QGGYPPPWQP---------------------NPYQTPVP
MAB_1196|M.abscessus_ATCC_1997 -------------------------------------------PPPPQGP
TH_3105|M.thermoresistible__bu HTPDQPTAADQAADQAGDRPD------------------EQAFDGSWAAA
Rv1078|M.tuberculosis_H37Rv GGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIG-WVIML
Mb1107|M.bovis_AF2122/97 GGYAPPPPGPAIRTMPTESYTPWITRVLAAFIDWAPYVVLVGIG-WVIML
MMAR_4389|M.marinum_M GGYAPPPPGPAIRALPAESYTPWITRVLAALIDFAPYVVVTGIG-WLIMM
MUL_0202|M.ulcerans_Agy99 GGYAPPPPGPAIRALPAESYTPWITRVLAALIDFAPYVVVTGIG-WLIMM
MAV_1202|M.avium_104 GGYAPPPPGPAIRTLPTQDYAPWLTRALAFVIDILPYVVVHGIG-TAILV
MLBr_02395|M.leprae_Br4923 GAYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIG-MLIQT
Mflv_2045|M.gilvum_PYR-GCK -------------TAARNPHTSWTRRVAAGILDAVPVMLGWGIW-ESVAI
Mvan_4672|M.vanbaalenii_PYR-1 GNLSGQPP-----AMPRRVYTSWSARVAAFFVDMVPLGLAWGIW-EVVAL
MSMEG_5266|M.smegmatis_MC2_155 GPYGPPT------VPNPQAYTPWFDRVIAFVIDQLPIAVVTVIG-YLVVF
MAB_1196|M.abscessus_ATCC_1997 GGYPPPPPAAGAPALPGGNFEIWIRRVGAYIIDVIPVALLSGIG-GGIAG
TH_3105|M.thermoresistible__bu GETAPAYGESPPAGFAPLDYPGAGAGTEPYQPSGYPAPPPGAQYPPPYPP
. . . . *
Rv1078|M.tuberculosis_H37Rv VTQTSS-CVTS-----ISEYDVGQFCVSQPSMIGQLVQWLLSVGG-----
Mb1107|M.bovis_AF2122/97 VTQTSS-CVTS-----ISEYDVGQFCVSQPSMIGQLVQWLLSVGG-----
MMAR_4389|M.marinum_M VTTTSS-CVTD-----ISQYDIGQYCVSQPSMIGQLAQWLLSLVG-----
MUL_0202|M.ulcerans_Agy99 VTTTPS-CVTD-----ISQYDIGQYCVSQPSMIGQLAQWLLSLVG-----
MAV_1202|M.avium_104 ATQQTA-CITD-----VTQYAVNQYCATQNSTLGLVAQWLASIVG-----
MLBr_02395|M.leprae_Br4923 LTKQEA-CVTD-----ITQYNVNQYCATQPTGIGMLAFWFAWLMA-----
Mflv_2045|M.gilvum_PYR-GCK GAASTE-CVT--------YDNGGVACTAIGSPAGDVVGVLMVFLS-----
Mvan_4672|M.vanbaalenii_PYR-1 RSATLD-CVT--------FDNGGVSCSSGISSVGYLAFALTVAVS-----
MSMEG_5266|M.smegmatis_MC2_155 GILAGA-SQG----------SSDGEITTGVGIVAAVLIFVLSLAP-----
MAB_1196|M.abscessus_ATCC_1997 GTATTADCVGDSFGDPMTGGMSYVSCQPEYTGVGWAAYILFSLAA-----
TH_3105|M.thermoresistible__bu GPQQPGYGYPAPPPYDAPRYPTPPYDPAQPPQFGAGQFGAAGYPDPNQPG
. .
Rv1078|M.tuberculosis_H37Rv -LAYLVWNYGYRQGTIGSSIGKSVLKFKVVSETTGQPIGFG--MSVVRQL
Mb1107|M.bovis_AF2122/97 -LAYLVWNYGYRQGTTGSSIGKSVLKFKVVSETTGQPIGFG--MSVVRQL
MMAR_4389|M.marinum_M -LAYLVWDYGYRQGTTGSSIGKSIMKFKVVSETTGEPLGFG--MSVVRQL
MUL_0202|M.ulcerans_Agy99 -LAYLVWDYGYRQGTTGSSIGKSIMKFKVVSETTGEPLGFG--MSVVRQL
MAV_1202|M.avium_104 -LFYLIWNYGYRQGTTGSSVGKSVMKFKVVSEVTGQPVGFG--MSVVRAL
MLBr_02395|M.leprae_Br4923 -TAYLVWNYGYRQGATGSSIGKTVMKFKVISEATGQPIGFG--MSVVRQL
Mflv_2045|M.gilvum_PYR-GCK -VAYLCWNFGLRQGRRGASIGKSVMGFRMVDEKTWQAVGFG--RSMLRLL
Mvan_4672|M.vanbaalenii_PYR-1 -VAYLVWNYGHRQGVSGSSVGKSVLRFQVLDEKTWRPVGFG--ASVLRQA
MSMEG_5266|M.smegmatis_MC2_155 -IAYGVWNMGYRQGTTGQSIGKSVMKFKVVSEQTGQPIGFL--MSLVRQV
MAB_1196|M.abscessus_ATCC_1997 -LAFAVWNWGLKQGTTGSSIGKGLLGIRVLGEATGQPIGFG--MSVVRQI
TH_3105|M.thermoresistible__bu YPGYYGYPQGYSQGYTQPPSTNTLSIWSLVISLISIPLLCSGLLSFLAPP
: : * ** . : : :: . .: *.:
Rv1078|M.tuberculosis_H37Rv AHFIDAIICFVGF--LFPLWDAKRQTLADKIMTTVCVPI-----------
Mb1107|M.bovis_AF2122/97 AHFIDAIICFVGF--LFPLWDAKRQTLADKIMTTVCVPI-----------
MMAR_4389|M.marinum_M AHIVDAIICYIGF--LFPLWDAKRQTLADKIMTTVCLPL-----------
MUL_0202|M.ulcerans_Agy99 AHIVDAVICYIGF--LFPLWDAKRQTLADKIMTTVCLPL-----------
MAV_1202|M.avium_104 AHFVDAIICFIGF--LFPLWDSKRQTLADKIMTTVCLPLDGSESPPS---
MLBr_02395|M.leprae_Br4923 AHFVDAVICCIGF--LFPLWDSKRQTLADKIMTTVCLPI-----------
Mflv_2045|M.gilvum_PYR-GCK VHVVDAVPLGIGF--LFPLWDRRRQTLADKLMGTVCVPVQGTVLGTRR--
Mvan_4672|M.vanbaalenii_PYR-1 VHLLDAAVCFIGF--LCPLWDRRRQTLADKLTGTVCVPKRY---------
MSMEG_5266|M.smegmatis_MC2_155 AHIVDGLICYVGY--LFPLWDAKRQTLADKIMTTVCVPVDRQPPQLSYPP
MAB_1196|M.abscessus_ATCC_1997 AHFLDAVICYIGF--LLPLFTAKRQTIADMLVKTVVVPK-----------
TH_3105|M.thermoresistible__bu AAIAGIVLGSLGLNQIKNTGENGRALAIGGIVAGAAVLVMVVVIILMIML
. . . :* : * . : . :
Rv1078|M.tuberculosis_H37Rv -------------------------------
Mb1107|M.bovis_AF2122/97 -------------------------------
MMAR_4389|M.marinum_M -------------------------------
MUL_0202|M.ulcerans_Agy99 -------------------------------
MAV_1202|M.avium_104 -------------------------------
MLBr_02395|M.leprae_Br4923 -------------------------------
Mflv_2045|M.gilvum_PYR-GCK -------------------------------
Mvan_4672|M.vanbaalenii_PYR-1 -------------------------------
MSMEG_5266|M.smegmatis_MC2_155 QQQFQQAYAPQYQQPYPPYPPQNPPGFNEMR
MAB_1196|M.abscessus_ATCC_1997 -------------------------------
TH_3105|M.thermoresistible__bu AAAAGA-------------------------