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QRQRKNSRFGLLWFGFWSTLFDMPGLPADHELFARAALGAYQRDPNTPLRLLSLSENATYLAGEPGGDTE PLVLRVHRPDYHSVAGIASELSWMAALRRETTVKTPELVPASDGDQVVAATVGDRTLYVDAVSFVPGCTA EEAPDVVGFAELGELTAIMHDHAQSWTAPASFTRFGWDLDAILGPDARWGNWRDAPALTKGDTAAIERAV TEITSRISKFGTGSDRFGLIHADLRLSNLMVDPSSPGAGITVIDFDDCGWGWHLADLAAVVSWLEDTPEA DAMIADWLRGYQAVRVLSEEHLALIPTFVMLRRVQLTAWIASHADADAAISVGADYARGTARLAERYLGD QSWLQDAVFASPLTPTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0780 | - | - | 100% (368) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_0270 | - | 7e-72 | 43.60% (328) | aminoglycoside phosphotransferase |
| M. smegmatis MC2 155 | MSMEG_5211 | - | 4e-08 | 26.10% (295) | hypothetical protein MSMEG_5211 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1236 | - | 2e-69 | 42.41% (323) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0951 | - | 1e-127 | 64.99% (337) | putative aminoglycoside phosphotransferase |
| M. marinum M | MMAR_2242 | gabT_1 | 4e-09 | 23.16% (354) | 4-aminobutyrate aminotransferase GabT_1 |
| M. avium 104 | MAV_1568 | - | 3e-05 | 25.19% (266) | phosphotransferase enzyme family protein, putative |
| M. thermoresistible (build 8) | TH_1675 | - | 1e-118 | 59.65% (342) | phosphotransferase enzyme family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5572 | - | 3e-71 | 42.99% (321) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1236|M.gilvum_PYR-GCK ----------------------MTAD-FTDDQTVAEKALAAFDLPQGSAL
Mvan_5572|M.vanbaalenii_PYR-1 ----------------------MSGDDVNDDRAVAEKALEAFDLPQGSTL
MSMEG_0780|M.smegmatis_MC2_155 MQRQRKNSRFGLLWFGFWSTLFDMPGLPADHELFARAALGAYQRDPNTPL
MAB_0951|M.abscessus_ATCC_1997 -----------------------MPGLPPNHSAFARAALTSYGRDPHTPL
TH_1675|M.thermoresistible__bu -----------------------MSGLPRDHERHARTVLPAYGRDPDTPL
MMAR_2242|M.marinum_M ------MKPVKAPTGFDFFAHPELPGPPVSERDAEKFVVENYEIS--ACA
MAV_1568|M.avium_104 ---------MLSIPRYPGDVTPQWLSAALSGRGAPVEVAEVDVAAIGTGQ
. . . :
Mflv_1236|M.gilvum_PYR-GCK RLLNLSENATYAVEEPG-CGHRSILRVHRKDYHRVDQIESELMWLDALRR
Mvan_5572|M.vanbaalenii_PYR-1 RLLNLSENATYAVEEPG-CGHRSILRVHRQNYHRVDQIESELLWLDALRR
MSMEG_0780|M.smegmatis_MC2_155 RLLSLSENATYLAGEPGGDTEPLVLRVHRPDYHSVAGIASELSWMAALRR
MAB_0951|M.abscessus_ATCC_1997 RLLSLSENATYLVD----DQRPMVLRAHRPGYHSLPAIRSELAWMSALRA
TH_1675|M.thermoresistible__bu RLLSVSENAIYLVD----DPDPMVLRVHRPGYHSPAAIRSELGWMTALRE
MMAR_2242|M.marinum_M RSLGSQQDANFLMTDPH-GNTVGVLKVANAVFSTEEIDAQVEAVEWVAER
MAV_1568|M.avium_104 TGATYRVTARYATDP---GDLPQTFVIKLPAQDDTVRDRVVIGYRSECAF
* : :
Mflv_1236|M.gilvum_PYR-GCK DSDVTVPTVIPAQDGRRVVTVEHDG---DERYVVHFEMVPG--AEPDEDT
Mvan_5572|M.vanbaalenii_PYR-1 DSDVTVPTVLPAHDGRRVVTVAHDG---ADRHVVHFEMVPG--AEPDENA
MSMEG_0780|M.smegmatis_MC2_155 ETTVKTPELVPASDGDQVVAATVGD---RTLYVDAVSFVPG--CTAEE-A
MAB_0951|M.abscessus_ATCC_1997 ETSVVTPELVRARNGSEVIAVGVDG---ITLHVDAMGFVPG--CTAEE-T
TH_1675|M.thermoresistible__bu QTTVATPRALRTVDGRDVVAAQPDGSRGSPVYVDAVTFIPG--CTAEE-Q
MMAR_2242|M.marinum_M DSALRLPRAIPDRRGQRHAPMSIGQ--EMLGVARLLTFLPGG-AMSQSGY
MAV_1568|M.avium_104 YSSVADRVQVPTPR-CFYSEITEDAMDFALLLADQAPAVQGDQLLGCGET
: : : . . : *
Mflv_1236|M.gilvum_PYR-GCK VTSTDFHTLGCITAALHDHARRWQRP-SGFSRFAWDWEHSLGGTPRWGRW
Mvan_5572|M.vanbaalenii_PYR-1 LTSTDFHTLGRITAALHDHARSWERP-AAFSRFAWDWENSLGGSPRWGRW
MSMEG_0780|M.smegmatis_MC2_155 PDVVGFAELGELTAIMHDHAQSWTAP-ASFTRFGWDLDAILGPDARWGNW
MAB_0951|M.abscessus_ATCC_1997 SGVVGYGKLGQLTAHMHHHAQGWRVP-PGFTRFRWDLDSMFGPQARWGDW
TH_1675|M.thermoresistible__bu PDAVGFEDLGRITAVMHRHVQSWSPP-AGFTRFRWDIDTTIGAHPRWGSW
MMAR_2242|M.marinum_M LAPKILAGMGNVTGRVSRALASFEHP-GLDRVLQWDPRFASESVDALIGH
MAV_1568|M.avium_104 EARLAVTALAGLHAPSWCDPVWLDFPGIAFGRPDEAGAGGMGEVAKMSAD
:. : . *
Mflv_1236|M.gilvum_PYR-GCK RDAVGVGEHEADVLTRAEALLHRRLTDYGTGP-DAFGLVHADLRLANLLV
Mvan_5572|M.vanbaalenii_PYR-1 RDAIGVGAQEAEVLERAERLLHRRLAEYGTGP-DTFGLVHADLRLANLLV
MSMEG_0780|M.smegmatis_MC2_155 RDAPALTKGDTAAIERAVTEITSRISKFGTGS-DRFGLIHADLRLSNLMV
MAB_0951|M.abscessus_ATCC_1997 RQAPGLTDADREAVDAAVRDIIRRLSEYGCTP-DRFGLIHADMRLSNLMV
TH_1675|M.thermoresistible__bu RHAAGLTPRDIDVVERAAAAVTARLTEFGYAP-DKFGLIHGDLRMANLMI
MMAR_2242|M.marinum_M VAEPAEAHRLAVATATAVNSLQRLDPQLPQQA-VHLDIADTNMVGS---P
MAV_1568|M.avium_104 ITLERLGDRMSAEDRETFAAAMGVIAPWLLSEYDRFALLHGDYRLDNLLF
: . : : . :
Mflv_1236|M.gilvum_PYR-GCK D----DDTITVIDFDDCGMGWYFYDFGTAVS-FFEDHPSVPEWQDAWVSG
Mvan_5572|M.vanbaalenii_PYR-1 D----GDTITVIDFDDCGFGWYFYDFGTAVS-FFEDHPSVPEWQEAWVSG
MSMEG_0780|M.smegmatis_MC2_155 DPSSPGAGITVIDFDDCGWGWHLADLAAVVS-WLEDTPEADAMIADWLRG
MAB_0951|M.abscessus_ATCC_1997 DPGRPGSDITVIDFDDCGWSWFMADLGAVVS-WVEDTPMAEAAVADWLDG
TH_1675|M.thermoresistible__bu DPADPGAPITVIDFDDSGWSWYLADLGAVVS-FIEHTPLAESIIADWLCG
MMAR_2242|M.marinum_M GSDGRRHPDGVIDFGDLTKTWAIAELATTVASCLYHAGAEPATILPVVAA
MAV_1568|M.avium_104 DPD--RTRVSVVDWQTLGVGLPARDLAYFTA-TSLDSPLRAAIEEELVAD
. *:*: ::. .: . :
Mflv_1236|M.gilvum_PYR-GCK YRSRRPISAAD-EDMLASFILLRRLLLLAWMGTHSHSKESQAISVTYAAG
Mvan_5572|M.vanbaalenii_PYR-1 YRTRRTLAASD-EDMLASFILLRRLLLLAWMGTHSHSKESQAISVTYAAG
MSMEG_0780|M.smegmatis_MC2_155 YQAVRVLSEEH-LALIPTFVMLRRVQLTAWIASHADADAAISVGADYARG
MAB_0951|M.abscessus_ATCC_1997 YQRVRRLSGDD-LGMIPAFVMLRRVMLTAWIASHADADAAIRVSDGFGAR
TH_1675|M.thermoresistible__bu YREVCELPQAD-LEMVPTFVMLRRLMLTGWIASHPDADAAITYRDGYPEG
MMAR_2242|M.marinum_M FHAIRPLSGDE-IEALWPMVIARAAVLLVSDLQQIAIDPGNEYAANTVQR
MAV_1568|M.avium_104 YHRALVAGGVNGYDRETCWRDYRLGVLQAPLISALGFAFAAATERGDDMV
:: . * * .
Mflv_1236|M.gilvum_PYR-GCK SCTLAEHYLSSD---GHRIF------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 SCKLAEQYLSSD---GHRLF------------------------------
MSMEG_0780|M.smegmatis_MC2_155 TARLAERYLGDQSWLQDAVFASPLTPTA----------------------
MAB_0951|M.abscessus_ATCC_1997 TARLAERYLTDRTWLREAVFGRRVG-------------------------
TH_1675|M.thermoresistible__bu TVQLAHRYLGDRNWLRDAVFSTRV--------------------------
MMAR_2242|M.marinum_M ERVILDQALLVPAPVMTGLIRDRLGIAQPQHHPLPKPHRPIIDIDPKSIV
MAV_1568|M.avium_104 LTMLGRGCRAIRELGTLELIG-----------------------------
: ::
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M RLDFSVESDAANRGAWLDGALAHELADSALSSNALAAATRYAATRADYIA
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M PLHPRSSPTIATGIDFWLREDTELVAPWAGDVVASTGAITLRTDSHELQL
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M TGAQPAPTSGQRVQAGQPWAKAPFGQRIHLALRPTDAPTAPHTVRPEYAP
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M GWLAVTEDPAALLGLEPAPSDGLDVLERRAATFAEVQEHYYDDPPQIERG
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M WRHYLLSTAGRSYLDMVNNVTVLGHAHPGVAAAAARQLERLNTNSRFNYA
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M VVVEFCERLTQLLPDPLDTVFLVNSGSEAGDLALRLAMAATGRRDVVAVG
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M EAYHGWTYATDAVSTSTADNPNALNTRPDWVHTVESPNSFRGKYRGAGAS
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M QYAHDAVAAIEDLVQSGRAPAAFIAETVYGSAGGMALPDGYLDAVYTAIR
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M AAGGLTIADEVQVGYGRLGKWFWGFEQQGVVPDIVAIAKATGNGHPVGAV
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M ITSKAIAQRFRSQGYFFSSTGGSPLSSAIGIAVLDALKSERLQHYALAVG
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1675|M.thermoresistible__bu --------------------------------------------------
MMAR_2242|M.marinum_M SHLIARIRKLATKHPLIGTVHGFGLYIGVEMVRDRKTLEPAAEETAAICD
MAV_1568|M.avium_104 --------------------------------------------------
Mflv_1236|M.gilvum_PYR-GCK -----------------------------------------------
Mvan_5572|M.vanbaalenii_PYR-1 -----------------------------------------------
MSMEG_0780|M.smegmatis_MC2_155 -----------------------------------------------
MAB_0951|M.abscessus_ATCC_1997 -----------------------------------------------
TH_1675|M.thermoresistible__bu -----------------------------------------------
MMAR_2242|M.marinum_M RMLELGVIIQPTGERMNILKTKPPLCIDMTAADYFADTLDRVLTEGW
MAV_1568|M.avium_104 -----------------------------------------------