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MPGLPPNHSAFARAALTSYGRDPHTPLRLLSLSENATYLVDDQRPMVLRAHRPGYHSLPAIRSELAWMSA LRAETSVVTPELVRARNGSEVIAVGVDGITLHVDAMGFVPGCTAEETSGVVGYGKLGQLTAHMHHHAQGW RVPPGFTRFRWDLDSMFGPQARWGDWRQAPGLTDADREAVDAAVRDIIRRLSEYGCTPDRFGLIHADMRL SNLMVDPGRPGSDITVIDFDDCGWSWFMADLGAVVSWVEDTPMAEAAVADWLDGYQRVRRLSGDDLGMIP AFVMLRRVMLTAWIASHADADAAIRVSDGFGARTARLAERYLTDRTWLREAVFGRRVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0951 | - | - | 100% (338) | putative aminoglycoside phosphotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1236 | - | 2e-64 | 39.87% (316) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1568 | - | 8e-06 | 28.76% (226) | phosphotransferase enzyme family protein, putative |
| M. smegmatis MC2 155 | MSMEG_0780 | - | 1e-127 | 64.99% (337) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_1675 | - | 1e-119 | 59.41% (340) | phosphotransferase enzyme family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5572 | - | 1e-68 | 40.88% (318) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1236|M.gilvum_PYR-GCK ----------------------MTAD-FTDDQTVAEKALAAFDLPQGSAL
Mvan_5572|M.vanbaalenii_PYR-1 ----------------------MSGDDVNDDRAVAEKALEAFDLPQGSTL
MAB_0951|M.abscessus_ATCC_1997 -----------------------MPGLPPNHSAFARAALTSYGRDPHTPL
MSMEG_0780|M.smegmatis_MC2_155 MQRQRKNSRFGLLWFGFWSTLFDMPGLPADHELFARAALGAYQRDPNTPL
TH_1675|M.thermoresistible__bu -----------------------MSGLPRDHERHARTVLPAYGRDPDTPL
MAV_1568|M.avium_104 -----------------------MLSIPRYPGDVTPQWLSAALSGRGAPV
. : * : :.:
Mflv_1236|M.gilvum_PYR-GCK RLLNLSENATYAVEEPG-CGHRSILRVHRKDYHRVDQIESELMWLDALRR
Mvan_5572|M.vanbaalenii_PYR-1 RLLNLSENATYAVEEPG-CGHRSILRVHRQNYHRVDQIESELLWLDALRR
MAB_0951|M.abscessus_ATCC_1997 RLLSLSENATYLVD----DQRPMVLRAHRPGYHSLPAIRSELAWMSALRA
MSMEG_0780|M.smegmatis_MC2_155 RLLSLSENATYLAGEPGGDTEPLVLRVHRPDYHSVAGIASELSWMAALRR
TH_1675|M.thermoresistible__bu RLLSVSENAIYLVD----DPDPMVLRVHRPGYHSPAAIRSELGWMTALRE
MAV_1568|M.avium_104 EVAEVDVAAIGTGQTGATYRVTARYATDPGDLPQTFVIKLPAQDDTVRDR
.: .:. * .. . * .
Mflv_1236|M.gilvum_PYR-GCK DSDVTVPTVIPAQDGRRVVTVEHDG---DERYVVHFEMVPGAEPDEDTVT
Mvan_5572|M.vanbaalenii_PYR-1 DSDVTVPTVLPAHDGRRVVTVAHDG---ADRHVVHFEMVPGAEPDENALT
MAB_0951|M.abscessus_ATCC_1997 ETSVVTPELVRARNGSEVIAVGVDG---ITLHVDAMGFVPGCTAEE-TSG
MSMEG_0780|M.smegmatis_MC2_155 ETTVKTPELVPASDGDQVVAATVGD---RTLYVDAVSFVPGCTAEE-APD
TH_1675|M.thermoresistible__bu QTTVATPRALRTVDGRDVVAAQPDGSRGSPVYVDAVTFIPGCTAEE-QPD
MAV_1568|M.avium_104 VVIGYRSECAFYSSVADRVQVPTPRCFYSEITEDAMDFALLLADQAPAVQ
. . : . . : :
Mflv_1236|M.gilvum_PYR-GCK STDFHTLGC------ITAALHDHARRWQRPSGFSR----FAWDWEHSLGG
Mvan_5572|M.vanbaalenii_PYR-1 STDFHTLGR------ITAALHDHARSWERPAAFSR----FAWDWENSLGG
MAB_0951|M.abscessus_ATCC_1997 VVGYGKLGQ------LTAHMHHHAQGWRVPPGFTR----FRWDLDSMFGP
MSMEG_0780|M.smegmatis_MC2_155 VVGFAELGE------LTAIMHDHAQSWTAPASFTR----FGWDLDAILGP
TH_1675|M.thermoresistible__bu AVGFEDLGR------ITAVMHRHVQSWSPPAGFTR----FRWDIDTTIGA
MAV_1568|M.avium_104 GDQLLGCGETEARLAVTALAGLHAPSWCDPVWLDFPGIAFGRPDEAGAGG
* :** *. * * : * : *
Mflv_1236|M.gilvum_PYR-GCK TPRWGRWRDAVGVGEHEADVLTRAEALLHRRLTDYG----TGPDAFGLVH
Mvan_5572|M.vanbaalenii_PYR-1 SPRWGRWRDAIGVGAQEAEVLERAERLLHRRLAEYG----TGPDTFGLVH
MAB_0951|M.abscessus_ATCC_1997 QARWGDWRQAPGLTDADREAVDAAVRDIIRRLSEYG----CTPDRFGLIH
MSMEG_0780|M.smegmatis_MC2_155 DARWGNWRDAPALTKGDTAAIERAVTEITSRISKFG----TGSDRFGLIH
TH_1675|M.thermoresistible__bu HPRWGSWRHAAGLTPRDIDVVERAAAAVTARLTEFG----YAPDKFGLIH
MAV_1568|M.avium_104 MGEVAKMSADITLERLGDRMSAEDRETFAAAMGVIAPWLLSEYDRFALLH
. . : . : . * *.*:*
Mflv_1236|M.gilvum_PYR-GCK ADLRLANLLVD----DDTITVIDFDDCGMGWYFYDFGTAVSFFEDHPSVP
Mvan_5572|M.vanbaalenii_PYR-1 ADLRLANLLVD----GDTITVIDFDDCGFGWYFYDFGTAVSFFEDHPSVP
MAB_0951|M.abscessus_ATCC_1997 ADMRLSNLMVDPGRPGSDITVIDFDDCGWSWFMADLGAVVSWVEDTPMAE
MSMEG_0780|M.smegmatis_MC2_155 ADLRLSNLMVDPSSPGAGITVIDFDDCGWGWHLADLAAVVSWLEDTPEAD
TH_1675|M.thermoresistible__bu GDLRMANLMIDPADPGAPITVIDFDDSGWSWYLADLGAVVSFIEHTPLAE
MAV_1568|M.avium_104 GDYRLDNLLFDPD--RTRVSVVDWQTLGVGLPARDLAYFTATSLDSPLRA
.* *: **:.* ::*:*:: * . *:. .: . *
Mflv_1236|M.gilvum_PYR-GCK EWQDAWVSGYRSRRPISAAD-EDMLASFILLRRLLLLAWMGTHSHSKESQ
Mvan_5572|M.vanbaalenii_PYR-1 EWQEAWVSGYRTRRTLAASD-EDMLASFILLRRLLLLAWMGTHSHSKESQ
MAB_0951|M.abscessus_ATCC_1997 AAVADWLDGYQRVRRLSGDD-LGMIPAFVMLRRVMLTAWIASHADADAAI
MSMEG_0780|M.smegmatis_MC2_155 AMIADWLRGYQAVRVLSEEH-LALIPTFVMLRRVQLTAWIASHADADAAI
TH_1675|M.thermoresistible__bu SIIADWLCGYREVCELPQAD-LEMVPTFVMLRRLMLTGWIASHPDADAAI
MAV_1568|M.avium_104 AIEEELVADYHRALVAGGVNGYDRETCWRDYRLGVLQAPLISALGFAFAA
: .*: . . : * * . : : :
Mflv_1236|M.gilvum_PYR-GCK AISVTYAAGSCTLAEHYLSSD---GHRIF--------
Mvan_5572|M.vanbaalenii_PYR-1 AISVTYAAGSCKLAEQYLSSD---GHRLF--------
MAB_0951|M.abscessus_ATCC_1997 RVSDGFGARTARLAERYLTDRTWLREAVFGRRVG---
MSMEG_0780|M.smegmatis_MC2_155 SVGADYARGTARLAERYLGDQSWLQDAVFASPLTPTA
TH_1675|M.thermoresistible__bu TYRDGYPEGTVQLAHRYLGDRNWLRDAVFSTRV----
MAV_1568|M.avium_104 ATERGDDMVLTMLGRGCRAIRELGTLELIG-------
*.. ::