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M. smegmatis MC2 155 MSMEG_0685 (-)

annotation: oxidoreductase, molybdopterin-binding subunit
coordinates: 768781 - 769776
length: 331

KAFGYHVATSPADAVATLAGHPGAAYLAGGTNLVDHMKLGVAEPDLLVDVSRLDLDQISVTDDGAVRIGA
NVRNSDLAADPVIRSHYPVLARALLSGASGQLRNTATTAGNLLQRTRCVYFQDVTTPCNKREPGSGCAAL
GGYARYHAILGASEHCVAVHPSDMAVAMSALDATVVVQGPDGQRRLPIDDFHRLPGDEPQRDTTLQHAEL
ITAVELPPPPVGAVSDYRKVRDRASYAFALVSVAAELTFTDTRQISSARIALGGVAHKPWRARRAESVLI
GDQPSDETFIAAADAELNAAEPLPGNEFKVELARRTLVAQLRMLTARRQQ*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_0685 - - 100% (331) oxidoreductase, molybdopterin-binding subunit
M. smegmatis MC2 155 MSMEG_0871 - 1e-77 49.84% (317) putative aldehyde or xanthine dehydrogenase, molybdopterin
M. smegmatis MC2 155 MSMEG_0744 - 4e-19 29.31% (331) carbon monoxide dehydrogenase medium chain

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0382c - 9e-16 25.48% (314) carbon monoxyde dehydrogenase medium subunit
M. gilvum PYR-GCK Mflv_0283 - 1e-152 82.01% (328) molybdopterin dehydrogenase, FAD-binding
M. tuberculosis H37Rv Rv0375c - 9e-16 25.48% (314) carbon monoxyde dehydrogenase medium subunit
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_0835 coxM_1 1e-71 46.30% (324) carbon monoxyde dehydrogenase (medium chain), CoxM_1
M. avium 104 - - - - -
M. thermoresistible (build 8) TH_0174 - 3e-19 28.66% (335) PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN)
M. ulcerans Agy99 MUL_4579 coxM_1 5e-71 45.99% (324) carbon monoxyde dehydrogenase (medium chain), CoxM_1
M. vanbaalenii PYR-1 Mvan_2077 - 9e-84 51.06% (329) molybdopterin dehydrogenase, FAD-binding

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0685|M.smegmatis_MC2_155      ---MKAFGYHVATSPADAVATLAGHPG-AAYLAGGTNLVDHMKLGVAEPD
Mflv_0283|M.gilvum_PYR-GCK          ---MKPFEYHLATSPADAVATLARHPD-AAYLAGGTNLVDHMKLGVAEPR
Mvan_2077|M.vanbaalenii_PYR-1       ---MRTFDHRRAGTVDDAIG-LASVPG-ARYFAGGTNLLDLMKSGVENPT
MMAR_0835|M.marinum_M               ---MFPFRYSKASDEQSALR--AAAAG-GRYIAGGTTLVDLMRETVERPD
MUL_4579|M.ulcerans_Agy99           ---MFPFRYSKASDEQSALR--AAAAG-GRYIAGGTTLVDLMRETVERPD
Mb0382c|M.bovis_AF2122/97           --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
Rv0375c|M.tuberculosis_H37Rv        --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
TH_0174|M.thermoresistible__bu      MQVPGPFEYERATSVDHAIGLLDRLGDGAMIVAGGHSLLPMMKLRIANPE
                                                     *:         .  .*** .*:  *:  : .* 

MSMEG_0685|M.smegmatis_MC2_155      LLVDVSRLDLDQISVTDD-----GAVRIGANVRNSDLAADPVIRSHYPVL
Mflv_0283|M.gilvum_PYR-GCK          LLVDVSRLDLTEVALTDD-----GGLSIGANVRNSDLAAHPVVRSRYPML
Mvan_2077|M.vanbaalenii_PYR-1       VLVDVNRLGLDAVVRTAA-----GGIAIGSGVTNSAVANHPLVRTDYPVL
MMAR_0835|M.marinum_M               SLVDINALPYQSIDVQP------GVIHVGSLVRMSDLAAHPVVRQQVPMV
MUL_4579|M.ulcerans_Agy99           SLVDINALPYQSIDVQP------GVIRVGSLVRMSNLAAHPVVRQQVPMV
Mb0382c|M.bovis_AF2122/97           YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
Rv0375c|M.tuberculosis_H37Rv        YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
TH_0174|M.thermoresistible__bu      YLVDINDLAGELGYIVV----NADAVRIGAMTRHREALESAELAQCCPIF
                                     ***:. *               . : :*: .          :    *:.

MSMEG_0685|M.smegmatis_MC2_155      ARALLSGASGQLRNTATTAGNLLQRTRCVYFQDVTTP-CNKREPGSGCAA
Mflv_0283|M.gilvum_PYR-GCK          ARALLSGASGQLRNAATTGGNLLQRTRCVYFQDVTTP-CNKREPGSGCAA
Mvan_2077|M.vanbaalenii_PYR-1       SQAILSGATTQIRNMATVGGNLMQRTRCPYFMDPRFERCNKRYPGSGCAA
MMAR_0835|M.marinum_M               SQALELSASAQLRNMASIGGNLLQRPRCLYFRDVSAA-CNRRGPDAGCAA
MUL_4579|M.ulcerans_Agy99           SQALELSASAQLRNMASIGGNLLQRPRCLYFRDVSAA-CNRRGPDAGCAA
Mb0382c|M.bovis_AF2122/97           RDAERVIADPVVRNRGTLGG------------------------------
Rv0375c|M.tuberculosis_H37Rv        RDAERVIADPVVRNRGTLGG------------------------------
TH_0174|M.thermoresistible__bu      ADAERVIADPVVRNRGTVGG------------------------------
                                      *    *   :** .: .*                              

MSMEG_0685|M.smegmatis_MC2_155      LGGYARYHAILGASEHCVAVHPSDMAVAMSALDATVVVQGPDGQRRLPID
Mflv_0283|M.gilvum_PYR-GCK          LGGYVRYHAILGASRHCVATHPSDMAVAMSALDAHIVVEGADGSRRIPAT
Mvan_2077|M.vanbaalenii_PYR-1       RDGFNREHAVFGTGGPCVAVHPSDMAVALAALDAVVHIKGPHGPRAATIS
MMAR_0835|M.marinum_M               IEGRNRTHAIFGASQHCCATHPSDLAVALVALDAVVLTRQIAGHRRFGLA
MUL_4579|M.ulcerans_Agy99           IEGRNRTHAIFGACRHCCATHPSDLAVALVALDAVVLTRQVAGHRRFGLA
Mb0382c|M.bovis_AF2122/97           --------------SLCQADPAEDLSTVCTVLDAVCLAKGPSGEREIAID
Rv0375c|M.tuberculosis_H37Rv        --------------SLCQADPAEDLSTVCTVLDAVCLAKGPSGEREIAID
TH_0174|M.thermoresistible__bu      --------------SLCQADPAEDLSTVCTVLDAVCVVRGPAGRREIGID
                                                    * *  ..*::..  .***    .   * *     

MSMEG_0685|M.smegmatis_MC2_155      DFHRLPGDEPQRDTTLQHAELITAVELPPPPVGAVSDYRKVRDRASYAFA
Mflv_0283|M.gilvum_PYR-GCK          DFHRLPGDEPQFDTVLDHGELITAVELPAPPPHAVSDYRKVRDRASYAFA
Mvan_2077|M.vanbaalenii_PYR-1       QFFSPPAADPDRDNGMAAADFITSVELPAAADTVHGWYLKVRDRRRYAFA
MMAR_0835|M.marinum_M               ELYRQPGDSPHWEHNLHPGELLVAIEIPVGPQLHRSGYLKVRDRESYQFA
MUL_4579|M.ulcerans_Agy99           ELYRHPGDSPHWEHNLHPGELLVAIEIPVGPQLHRSGYLKVRDRESYQFA
Mb0382c|M.bovis_AF2122/97           DFLVGP-----YETALAHNEVLIEVRIPLR-HNTSSAYAKVERRVG-DWA
Rv0375c|M.tuberculosis_H37Rv        DFLVGP-----YETALAHNEVLIEVRIPLR-HNTSSAYAKVERRVG-DWA
TH_0174|M.thermoresistible__bu      DFLVGP-----YETALAHNEILLEVKIPLR-PNSSNAYAKVERRVG-DWA
                                    ::   *      :  :   :.:  :.:*       . * **. *    :*

MSMEG_0685|M.smegmatis_MC2_155      LVSVAAELTFTDTRQISSARIALGGVAHKPWRARRAESVLIGDQPSDETF
Mflv_0283|M.gilvum_PYR-GCK          LVSVAAELSFVG-ESIATARIALGGVAHKPWRARRAEQMLAGAEATDETF
Mvan_2077|M.vanbaalenii_PYR-1       LVSVAAVLRFDSDGVVASAAVALGGVADRPWRVPAAEAVLTGRRPTPQLF
MMAR_0835|M.marinum_M               LVSAAVALDIAA-GTIRTARVAAGGVGTVPWRLPAVEAALRGRPPDADLF
MUL_4579|M.ulcerans_Agy99           LVSAAVALDIAA-GTIRTARVAAGGVGTVPWRLPAVEAALRGRPPDADLF
Mb0382c|M.bovis_AF2122/97           ITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEVF
Rv0375c|M.tuberculosis_H37Rv        ITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEVF
TH_0174|M.thermoresistible__bu      VTAAGAAVTLDG-QTVTAARIGLTAVNPDAAALAEISRRLTGRPATEETF
                                    :.:... : :     : :* :.  .*   .      .  * *  .  : *

MSMEG_0685|M.smegmatis_MC2_155      IAAADAELNAAEPLPGNE----FKVELARRTLVAQLRMLTARRQQ-----
Mflv_0283|M.gilvum_PYR-GCK          AAAADAEISAAEPLPGNE----FKVELARRTLMAQLRMLTERGTR-----
Mvan_2077|M.vanbaalenii_PYR-1       RSAADTALADAAPLSHNG----FKLPLARNAVMRALVLATGR--------
MMAR_0835|M.marinum_M               RRAAALSAIGAKPLSENR----FKVELLKRVVEKQLTVVAAMP-------
MUL_4579|M.ulcerans_Agy99           RRAAALSAIGAKPLSENR----FKVELLKRVVEKQLTVVAAMP-------
Mb0382c|M.bovis_AF2122/97           AEAGRRAAQACTPVTDVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPAAP
Rv0375c|M.tuberculosis_H37Rv        AEAGRRAAQACTPVTDVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPAAP
TH_0174|M.thermoresistible__bu      AEAGRLAAQACEPVTDVRGTADYKRHLAAELTTRTLRTAVQRIQQRHGGA
                                      *.      . *:.       :*  *  .     *   .          

MSMEG_0685|M.smegmatis_MC2_155      ----
Mflv_0283|M.gilvum_PYR-GCK          ----
Mvan_2077|M.vanbaalenii_PYR-1       ----
MMAR_0835|M.marinum_M               ----
MUL_4579|M.ulcerans_Agy99           ----
Mb0382c|M.bovis_AF2122/97           EA--
Rv0375c|M.tuberculosis_H37Rv        EA--
TH_0174|M.thermoresistible__bu      QPCR

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_0685	-	-	100% (331)	oxidoreductase, molybdopterin-binding subunit
M. smegmatis MC2 155	MSMEG_0871	-	1e-77	49.84% (317)	putative aldehyde or xanthine dehydrogenase, molybdopterin
M. smegmatis MC2 155	MSMEG_0744	-	4e-19	29.31% (331)	carbon monoxide dehydrogenase medium chain