For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPEYLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHR EILDSDALAAVCPIFRDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGEREIAI DDFLVGPYETALAHNEVLIEVRIPLRHNTSSAYAKVERRVGDWAITAAGAAVTLDGQTILAARVGLTAVN PDPVALAELSAGLVGQPATEEVFAEAGRRAAQACTPVTDVRGTAEYKRHLAGELTVRTLRTAAGRVLGAP AAPEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0375c | - | - | 100% (286) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0382c | - | 1e-161 | 100.00% (286) | carbon monoxyde dehydrogenase medium subunit |
| M. gilvum PYR-GCK | Mflv_1571 | - | 1e-31 | 32.10% (271) | carbon-monoxide dehydrogenase (acceptor) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2926c | - | 5e-08 | 26.87% (201) | putative oxidoreductase (molybdopterin dehydrogenase) |
| M. marinum M | MMAR_0655 | coxM | 1e-133 | 83.69% (282) | carbon monoxyde dehydrogenase (medium chain), CoxM |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0744 | - | 1e-128 | 80.14% (282) | carbon monoxide dehydrogenase medium chain |
| M. thermoresistible (build 8) | TH_0174 | - | 1e-127 | 80.87% (277) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN) |
| M. ulcerans Agy99 | MUL_0587 | coxM_2 | 9e-33 | 32.96% (270) | aerobic-type carbon monoxide dehydrogenase, CoxM_2 |
| M. vanbaalenii PYR-1 | Mvan_5185 | - | 6e-31 | 32.74% (281) | carbon-monoxide dehydrogenase (acceptor) |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1571|M.gilvum_PYR-GCK -MKAAPFAYHRPDTVADAVSLLGEYGDDAKILAGGQSLVPMLAMRLTHFE
Mvan_5185|M.vanbaalenii_PYR-1 -MKAAPFAYHRPDTVADAVSMLGEFGDDAKILAGGQSLVPMLAMRLTHFE
MUL_0587|M.ulcerans_Agy99 -MKPASFDYHRPDTAEEAVDLLAELGEDAKILPGGQSLVPMLSMRLAFFD
Rv0375c|M.tuberculosis_H37Rv --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
Mb0382c|M.bovis_AF2122/97 --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
MMAR_0655|M.marinum_M MQVPGPFEYERATSVDHAIGLLDRLGEGARLVAGGHSLLPMMKLRIANPE
MSMEG_0744|M.smegmatis_MC2_155 MQVPGPFEYERATSVDHAVGLLDRLGEDARIVAGGHSLLPMMKLRIANPE
TH_0174|M.thermoresistible__bu MQVPGPFEYERATSVDHAIGLLDRLGDGAMIVAGGHSLLPMMKLRIANPE
MAB_2926c|M.abscessus_ATCC_199 ----MDLYSIDSVLIPRDRADLSGLGTQDGVLAGGTWLMSQPQPGLR---
* * ::.** *:. :
Mflv_1571|M.gilvum_PYR-GCK NLIDISRIEELRNIELRNG--ADSSVRIGAGTPHALVGMDDEVAESVPLL
Mvan_5185|M.vanbaalenii_PYR-1 NLIDISRVDELRNIEPRG-----DAVRIGAGTPHALVGMDDEVAESVPLL
MUL_0587|M.ulcerans_Agy99 HLIDISRLGELQGIRLRD-----DQLWIGAGTPDSKVGTNSQVHQSIPLL
Rv0375c|M.tuberculosis_H37Rv YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
Mb0382c|M.bovis_AF2122/97 YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
MMAR_0655|M.marinum_M YLVDINDLAPELGYVIT----DPTLVRIGAMARHREILESEALAAVCPIF
MSMEG_0744|M.smegmatis_MC2_155 YLVDINDLAVELGYVIT----DPTLVRIGAMARHRQVLESDPLAAVCPIF
TH_0174|M.thermoresistible__bu YLVDINDLAGELGYIVV----NADAVRIGAMTRHREALESAELAQCCPIF
MAB_2926c|M.abscessus_ATCC_199 RLVDLTGMRWPDLVVDAGG---LEVAATCSIERLINASYPPAWQATALFG
*:*:. : : :
Mflv_1571|M.gilvum_PYR-GCK TLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEIEATSGRGT
Mvan_5185|M.vanbaalenii_PYR-1 TLSTPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEMEATSARGT
MUL_0587|M.ulcerans_Agy99 ARATPYIGHFQIRNRGTLGGSIAHADAAGEYPTVALTLDAVMEVLSPRGH
Rv0375c|M.tuberculosis_H37Rv RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGE
Mb0382c|M.bovis_AF2122/97 RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGE
MMAR_0655|M.marinum_M RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLARGSSGE
MSMEG_0744|M.smegmatis_MC2_155 RDAERVIADPVVRNRGTLGGSLCQADPAEDLTTVCTILGAVCLARGPGGE
TH_0174|M.thermoresistible__bu ADAERVIADPVVRNRGTVGGSLCQADPAEDLSTVCTVLDAVCVVRGPAGR
MAB_2926c|M.abscessus_ATCC_199 QCARALLASFKIWRTATVGGNICLGLPAGAMISLCAALDAELHIWRHDGT
: :. : .*:** :. . .* ::. *.* *
Mflv_1571|M.gilvum_PYR-GCK RR-IPAAEFFTGLWETALASDEILTAVSFPVWSGRCGFAVQEFARRHGDF
Mvan_5185|M.vanbaalenii_PYR-1 RR-IPAAEFFTGLWETALAADEILTAVSFPVWTGHCGFAVQEFARRHGDF
MUL_0587|M.ulcerans_Agy99 RK-IPAAEFFTGLWETAMEPDEVLTGVRFPTWTGKSGFAMREFSRRHGDF
Rv0375c|M.tuberculosis_H37Rv RE-IAIDDFLVGPYETALAHNEVLIEVRIPLRH-NTSSAYAKVERRVGDW
Mb0382c|M.bovis_AF2122/97 RE-IAIDDFLVGPYETALAHNEVLIEVRIPLRH-NTSSAYAKVERRVGDW
MMAR_0655|M.marinum_M RE-IAIDEFQAGPYETTLAPSEMLVEVRIPVRH-NTSSAYAKVERRVGDW
MSMEG_0744|M.smegmatis_MC2_155 RE-IGIDDFLVGPYETALAHNEMLVEVRIPVRH-RTSSAYAKVERRVGDW
TH_0174|M.thermoresistible__bu RE-IGIDDFLVGPYETALAHNEILLEVKIPLRP-NSSNAYAKVERRVGDW
MAB_2926c|M.abscessus_ATCC_199 DERCTITEFVTGINETVLHPGDVLRAITFPSSALSQPTALRKIAYSP--L
. :* .* **.: .::* : :* * :.
Mflv_1571|M.gilvum_PYR-GCK AIAGATVAVALDEDDTVTRCGIGMLGMGSTPERGTAAEAAVLGRPVADIT
Mvan_5185|M.vanbaalenii_PYR-1 AIAGATLAVELDGRDRVARCGIGLLGMGSTPERGTPAEQAVVGRPVTDIT
MUL_0587|M.ulcerans_Agy99 AIAGAAVAVQLDDEHRVSRCAIGLLGLGPTPRRATAAEAAVLGKPIDELV
Rv0375c|M.tuberculosis_H37Rv AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
Mb0382c|M.bovis_AF2122/97 AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
MMAR_0655|M.marinum_M AVTAAGAAVTLNN-DTITAARVGLTAVNPDPAALAELAAALVGRPANEDT
MSMEG_0744|M.smegmatis_MC2_155 AVTAAGAQVTLDG-DSIVAARVGLTAVNPDPDALRALADDLIGKPATEET
TH_0174|M.thermoresistible__bu AVTAAGAAVTLDG-QTVTAARIGLTAVNPDAAALAEISRRLTGRPATEET
MAB_2926c|M.abscessus_ATCC_199 GRSGALVTGRLDG----ADIVLGITAATRRP---------IVLRVPAEAR
. :.* *: :*: . . : : :
Mflv_1571|M.gilvum_PYR-GCK AEELGRLAVSTLHDIPADLQGSAAYRSRVCATMVARAWSEATTAARHTTE
Mvan_5185|M.vanbaalenii_PYR-1 AEEVGRLAVSELHDVPADLQGRPAYRSKVGATMVARAWSQATTAALETRE
MUL_0587|M.ulcerans_Agy99 PEQIGQSAMSGLDDIASDLQGPASYRAQVGAVMTTRAWSRAVQEAN--AE
Rv0375c|M.tuberculosis_H37Rv FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
Mb0382c|M.bovis_AF2122/97 FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
MMAR_0655|M.marinum_M FAEAGRRAGQACEPVT-DIRGTADYKRHLAAELTIRTLRSAVGRVRNQPA
MSMEG_0744|M.smegmatis_MC2_155 FAAAGELAVQACEPVT-DTRGSADYKRHLARELTIRTMRTAVERVRTAPA
TH_0174|M.thermoresistible__bu FAEAGRLAAQACEPVT-DVRGTADYKRHLAAELTTRTLRTAVQRIQQRHG
MAB_2926c|M.abscessus_ATCC_199 RAREAVAAIPGVEFHT-DAHGTAEWRGAVTTQLAGEVAAELTGALS----
. * . * :* . :: : :. .. .
Mflv_1571|M.gilvum_PYR-GCK ALHA--
Mvan_5185|M.vanbaalenii_PYR-1 ALNA--
MUL_0587|M.ulcerans_Agy99 TAHA--
Rv0375c|M.tuberculosis_H37Rv APEA--
Mb0382c|M.bovis_AF2122/97 APEA--
MMAR_0655|M.marinum_M PEGN--
MSMEG_0744|M.smegmatis_MC2_155 PEGN--
TH_0174|M.thermoresistible__bu GAQPCR
MAB_2926c|M.abscessus_ATCC_199 ------