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M. smegmatis MC2 155 MSMEG_0744 (-)

annotation: carbon monoxide dehydrogenase medium chain
coordinates: 830754 - 831644
length: 296

MQVPGPFEYERATSVDHAVGLLDRLGEDARIVAGGHSLLPMMKLRIANPEYLVDINDLAVELGYVITDPT
LVRIGAMARHRQVLESDPLAAVCPIFRDAERVIADPVVRNRGTLGGSLCQADPAEDLTTVCTILGAVCLA
RGPGGEREIGIDDFLVGPYETALAHNEMLVEVRIPVRHRTSSAYAKVERRVGDWAVTAAGAQVTLDGDSI
VAARVGLTAVNPDPDALRALADDLIGKPATEETFAAAGELAVQACEPVTDTRGSADYKRHLARELTIRTM
RTAVERVRTAPAPEGN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0744--100% (296)carbon monoxide dehydrogenase medium chain
M. smegmatis MC2 155MSMEG_5882-1e-3536.95% (295) carbon monoxide dehydrogenase medium chain
M. smegmatis MC2 155MSMEG_2463-2e-3031.94% (288) nicotine dehydrogenase chain A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0382c-1e-12880.14% (282) carbon monoxyde dehydrogenase medium subunit
M. gilvum PYR-GCKMflv_1571-6e-3533.68% (288) carbon-monoxide dehydrogenase (acceptor)
M. tuberculosis H37RvRv0375c-1e-12880.14% (282) carbon monoxyde dehydrogenase medium subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2926c-8e-0727.24% (268) putative oxidoreductase (molybdopterin dehydrogenase)
M. marinum MMMAR_0655coxM1e-14184.12% (296) carbon monoxyde dehydrogenase (medium chain), CoxM
M. avium 104-----
M. thermoresistible (build 8)TH_0174-1e-13078.12% (288) PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN)
M. ulcerans Agy99MUL_0587coxM_21e-3633.56% (292) aerobic-type carbon monoxide dehydrogenase, CoxM_2
M. vanbaalenii PYR-1Mvan_5185-4e-3434.16% (281) carbon-monoxide dehydrogenase (acceptor)

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1571|M.gilvum_PYR-GCK          -MKAAPFAYHRPDTVADAVSLLGEYGDDAKILAGGQSLVPMLAMRLTHFE
Mvan_5185|M.vanbaalenii_PYR-1       -MKAAPFAYHRPDTVADAVSMLGEFGDDAKILAGGQSLVPMLAMRLTHFE
MUL_0587|M.ulcerans_Agy99           -MKPASFDYHRPDTAEEAVDLLAELGEDAKILPGGQSLVPMLSMRLAFFD
MSMEG_0744|M.smegmatis_MC2_155      MQVPGPFEYERATSVDHAVGLLDRLGEDARIVAGGHSLLPMMKLRIANPE
MMAR_0655|M.marinum_M               MQVPGPFEYERATSVDHAIGLLDRLGEGARLVAGGHSLLPMMKLRIANPE
Mb0382c|M.bovis_AF2122/97           --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
Rv0375c|M.tuberculosis_H37Rv        --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
TH_0174|M.thermoresistible__bu      MQVPGPFEYERATSVDHAIGLLDRLGDGAMIVAGGHSLLPMMKLRIANPE
MAB_2926c|M.abscessus_ATCC_199      ----MDLYSIDSVLIPRDRADLSGLGTQDGVLAGGTWLMSQPQPGLR---
                                                         *   *    ::.**  *:.     :    

Mflv_1571|M.gilvum_PYR-GCK          NLIDISRIEELRNIELRNG--ADSSVRIGAGTPHALVGMDDEVAESVPLL
Mvan_5185|M.vanbaalenii_PYR-1       NLIDISRVDELRNIEPRG-----DAVRIGAGTPHALVGMDDEVAESVPLL
MUL_0587|M.ulcerans_Agy99           HLIDISRLGELQGIRLRD-----DQLWIGAGTPDSKVGTNSQVHQSIPLL
MSMEG_0744|M.smegmatis_MC2_155      YLVDINDLAVELGYVIT----DPTLVRIGAMARHRQVLESDPLAAVCPIF
MMAR_0655|M.marinum_M               YLVDINDLAPELGYVIT----DPTLVRIGAMARHREILESEALAAVCPIF
Mb0382c|M.bovis_AF2122/97           YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
Rv0375c|M.tuberculosis_H37Rv        YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
TH_0174|M.thermoresistible__bu      YLVDINDLAGELGYIVV----NADAVRIGAMTRHREALESAELAQCCPIF
MAB_2926c|M.abscessus_ATCC_199      RLVDLTGMRWPDLVVDAGG---LEVAATCSIERLINASYPPAWQATALFG
                                     *:*:. :                     :                  : 

Mflv_1571|M.gilvum_PYR-GCK          TLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEIEATSGRGT
Mvan_5185|M.vanbaalenii_PYR-1       TLSTPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEMEATSARGT
MUL_0587|M.ulcerans_Agy99           ARATPYIGHFQIRNRGTLGGSIAHADAAGEYPTVALTLDAVMEVLSPRGH
MSMEG_0744|M.smegmatis_MC2_155      RDAERVIADPVVRNRGTLGGSLCQADPAEDLTTVCTILGAVCLARGPGGE
MMAR_0655|M.marinum_M               RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLARGSSGE
Mb0382c|M.bovis_AF2122/97           RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGE
Rv0375c|M.tuberculosis_H37Rv        RDAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSGE
TH_0174|M.thermoresistible__bu      ADAERVIADPVVRNRGTVGGSLCQADPAEDLSTVCTVLDAVCVVRGPAGR
MAB_2926c|M.abscessus_ATCC_199      QCARALLASFKIWRTATVGGNICLGLPAGAMISLCAALDAELHIWRHDGT
                                      :   :.   :   .*:** :. . .*    ::.  *.*        * 

Mflv_1571|M.gilvum_PYR-GCK          RR-IPAAEFFTGLWETALASDEILTAVSFPVWSGRCGFAVQEFARRHGDF
Mvan_5185|M.vanbaalenii_PYR-1       RR-IPAAEFFTGLWETALAADEILTAVSFPVWTGHCGFAVQEFARRHGDF
MUL_0587|M.ulcerans_Agy99           RK-IPAAEFFTGLWETAMEPDEVLTGVRFPTWTGKSGFAMREFSRRHGDF
MSMEG_0744|M.smegmatis_MC2_155      RE-IGIDDFLVGPYETALAHNEMLVEVRIPVRH-RTSSAYAKVERRVGDW
MMAR_0655|M.marinum_M               RE-IAIDEFQAGPYETTLAPSEMLVEVRIPVRH-NTSSAYAKVERRVGDW
Mb0382c|M.bovis_AF2122/97           RE-IAIDDFLVGPYETALAHNEVLIEVRIPLRH-NTSSAYAKVERRVGDW
Rv0375c|M.tuberculosis_H37Rv        RE-IAIDDFLVGPYETALAHNEVLIEVRIPLRH-NTSSAYAKVERRVGDW
TH_0174|M.thermoresistible__bu      RE-IGIDDFLVGPYETALAHNEILLEVKIPLRP-NSSNAYAKVERRVGDW
MAB_2926c|M.abscessus_ATCC_199      DERCTITEFVTGINETVLHPGDVLRAITFPSSALSQPTALRKIAYSP--L
                                     .     :* .*  **.:  .::*  : :*        *  :.       

Mflv_1571|M.gilvum_PYR-GCK          AIAGATVAVALDEDDTVTRCGIGMLGMGSTPERGTAAEAAVLGRPVADIT
Mvan_5185|M.vanbaalenii_PYR-1       AIAGATLAVELDGRDRVARCGIGLLGMGSTPERGTPAEQAVVGRPVTDIT
MUL_0587|M.ulcerans_Agy99           AIAGAAVAVQLDDEHRVSRCAIGLLGLGPTPRRATAAEAAVLGKPIDELV
MSMEG_0744|M.smegmatis_MC2_155      AVTAAGAQVTLDG-DSIVAARVGLTAVNPDPDALRALADDLIGKPATEET
MMAR_0655|M.marinum_M               AVTAAGAAVTLNN-DTITAARVGLTAVNPDPAALAELAAALVGRPANEDT
Mb0382c|M.bovis_AF2122/97           AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
Rv0375c|M.tuberculosis_H37Rv        AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
TH_0174|M.thermoresistible__bu      AVTAAGAAVTLDG-QTVTAARIGLTAVNPDAAALAEISRRLTGRPATEET
MAB_2926c|M.abscessus_ATCC_199      GRSGALVTGRLDG----ADIVLGITAATRRP---------IVLRVPAEAR
                                    . :.*     *:         :*: .    .         :  :   :  

Mflv_1571|M.gilvum_PYR-GCK          AEELGRLAVSTLHDIPADLQGSAAYRSRVCATMVARAWSEATTAARHTTE
Mvan_5185|M.vanbaalenii_PYR-1       AEEVGRLAVSELHDVPADLQGRPAYRSKVGATMVARAWSQATTAALETRE
MUL_0587|M.ulcerans_Agy99           PEQIGQSAMSGLDDIASDLQGPASYRAQVGAVMTTRAWSRAVQEAN--AE
MSMEG_0744|M.smegmatis_MC2_155      FAAAGELAVQACEPVT-DTRGSADYKRHLARELTIRTMRTAVERVRTAPA
MMAR_0655|M.marinum_M               FAEAGRRAGQACEPVT-DIRGTADYKRHLAAELTIRTLRSAVGRVRNQPA
Mb0382c|M.bovis_AF2122/97           FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
Rv0375c|M.tuberculosis_H37Rv        FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
TH_0174|M.thermoresistible__bu      FAEAGRLAAQACEPVT-DVRGTADYKRHLAAELTTRTLRTAVQRIQQRHG
MAB_2926c|M.abscessus_ATCC_199      RAREAVAAIPGVEFHT-DAHGTAEWRGAVTTQLAGEVAAELTGALS----
                                        .  *       . * :* . ::  :   :. ..    .        

Mflv_1571|M.gilvum_PYR-GCK          ALHA--
Mvan_5185|M.vanbaalenii_PYR-1       ALNA--
MUL_0587|M.ulcerans_Agy99           TAHA--
MSMEG_0744|M.smegmatis_MC2_155      PEGN--
MMAR_0655|M.marinum_M               PEGN--
Mb0382c|M.bovis_AF2122/97           APEA--
Rv0375c|M.tuberculosis_H37Rv        APEA--
TH_0174|M.thermoresistible__bu      GAQPCR
MAB_2926c|M.abscessus_ATCC_199      ------