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VTGGAIRLHQLAKAFEGVPAVAGIDLDIPAGQFYSLLGASGCGKTTTLRMIAGFEKPDSGRIELDGRDVA SDPPHKRPVNTVFQTYALFPFMSVWDNVAFGLRYQKAPRAEVTRRVGEALELVRMAEFAKRKPAQLSGGQ QQRVALARALVLRPRVLLLDEPLGALDAKLRKQLQLELRALQREVGITFVYVTHDQEEALTMSDQIAVMA EGRVEQVGAPTEIYSAPATTYVAGFLGAANIFDAELTEAAGATGGTAVCTAMSTRLSAWVDGAAAPGPAA IVIRPERITLQGPDEPVAAGSNVITGTVSHVVYLGASTQVHVDVGEANSLVVEVPNHAGPQSVSQQAGAR VHCVCTPDAVRVLTRSPVAVIADPVVEPETALSAH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0662 | - | - | 100% (385) | putrescine transport ATP-binding protein PotG |
| M. smegmatis MC2 155 | MSMEG_3281 | - | 2e-94 | 51.61% (372) | spermidine/putrescine ABC transporter ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_4761 | - | 2e-78 | 48.63% (329) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-65 | 48.15% (270) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3138 | - | 9e-90 | 47.73% (375) | spermidine/putrescine ABC transporter ATPase subunit |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 8e-65 | 48.15% (270) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 1e-60 | 43.64% (275) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1655 | - | 8e-66 | 53.78% (225) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 1e-65 | 41.96% (367) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 2e-63 | 46.49% (271) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_2424 | - | 2e-64 | 50.41% (242) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 3e-65 | 49.10% (277) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3387 | - | 8e-90 | 48.92% (372) | spermidine/putrescine ABC transporter ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3138|M.gilvum_PYR-GCK MRNRLRRTAESAIVYPQPGGSIEEDGALTRAHTATGHGIGQGAASTKGGP
Mvan_3387|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0662|M.smegmatis_MC2_155 ----------------------------------------------MTGG
Mb2419c|M.bovis_AF2122/97 ---------------------------------------MT--------Y
Rv2397c|M.tuberculosis_H37Rv ---------------------------------------MT--------Y
MMAR_3715|M.marinum_M ---------------------------------MKKETSLTGPGT--GGH
MUL_3658|M.ulcerans_Agy99 ---------------------------------------MTGPGT--GGH
MAV_1785|M.avium_104 ---------------------------------------MTDAGTDRGDI
TH_2424|M.thermoresistible__bu ---------------------------------------MT--------D
MAB_1655|M.abscessus_ATCC_1997 ---------------------------------------MT------AEN
MLBr_01089|M.leprae_Br4923 ------------------------------------------------MA
Mflv_3138|M.gilvum_PYR-GCK VIEIDHVTKRFG-DYLAVSDADFSIASGEFFSMLGPSGCGKTTTLRMIAG
Mvan_3387|M.vanbaalenii_PYR-1 MIEIDHVTKSFG-DYVAVADADFSIASGEFFSMLGPSGCGKTTTLRMIAG
MSMEG_0662|M.smegmatis_MC2_155 AIRLHQLAKAFE-GVPAVAGIDLDIPAGQFYSLLGASGCGKTTTLRMIAG
Mb2419c|M.bovis_AF2122/97 AIVVADATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAG
Rv2397c|M.tuberculosis_H37Rv AIVVADATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAG
MMAR_3715|M.marinum_M AIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAG
MUL_3658|M.ulcerans_Agy99 AIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAG
MAV_1785|M.avium_104 AITVRDAYKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAG
TH_2424|M.thermoresistible__bu AITVRGANKRYG-DFAALDNVDFAVPAGSLTALLGPSGSGKSTLLRAIAG
MAB_1655|M.abscessus_ATCC_1997 TITVRGANKHYG-DFAALDNIDFDVPSGSLTALLGPSGSGKSTLLRSIAG
MLBr_01089|M.leprae_Br4923 EIVLEHVNKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAG
* : * : . *: .: :. *.: ::*.**.**:* *. ***
Mflv_3138|M.gilvum_PYR-GCK FETPSEGAIRLEGADVSKTPPNKRNVNTVFQHYALFPHMTVWDNVAYGPR
Mvan_3387|M.vanbaalenii_PYR-1 FETPTEGAIRLEGADVSRTPPNKRNVNTVFQHYALFPHMTVWDNVAYGPR
MSMEG_0662|M.smegmatis_MC2_155 FEKPDSGRIELDGRDVASDPPHKRPVNTVFQTYALFPFMSVWDNVAFGLR
Mb2419c|M.bovis_AF2122/97 LDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLK
Rv2397c|M.tuberculosis_H37Rv LDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLK
MMAR_3715|M.marinum_M LDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLK
MUL_3658|M.ulcerans_Agy99 LDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLK
MAV_1785|M.avium_104 LDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLK
TH_2424|M.thermoresistible__bu LDRPDTGTITINGRDVTDVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLK
MAB_1655|M.abscessus_ATCC_1997 LDNPDSGTITINGRDVTGVPPQRRDIGFVFQHYAAFKHLTVWENVAFGLK
MLBr_01089|M.leprae_Br4923 LEDISSGELRIDGDRVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLM
:: * : : * * .*: * : *** ** : .::* :*:*:
Mflv_3138|M.gilvum_PYR-GCK SKKLDKGEIRKRVDELLEIVRLSDFAERKPAQLSGGQQQRVALARALVNY
Mvan_3387|M.vanbaalenii_PYR-1 SKKLGKGEIRKRVDELLDIVRLTDFAERKPAQLSGGQQQRVALARALVNY
MSMEG_0662|M.smegmatis_MC2_155 YQKAPRAEVTRRVGEALELVRMAEFAKRKPAQLSGGQQQRVALARALVLR
Mb2419c|M.bovis_AF2122/97 IRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVD
Rv2397c|M.tuberculosis_H37Rv IRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVD
MMAR_3715|M.marinum_M IRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVD
MUL_3658|M.ulcerans_Agy99 IRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVD
MAV_1785|M.avium_104 VRKRPKAEIKAKVDNLLEVVGLSGFQGRYPNQLSGGQRQRMALARALAVD
TH_2424|M.thermoresistible__bu IRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQLSGGQRQRMALARALAVD
MAB_1655|M.abscessus_ATCC_1997 IRKKPKAEIKKKVDDLLEVVGLSGFHTRYPAQLSGGQRQRMALARALAVD
MLBr_01089|M.leprae_Br4923 LAKVKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAIVRH
: : *: :*.: ::: :: : * * ******:**:*:.**:.
Mflv_3138|M.gilvum_PYR-GCK PSALLLDEPLGALDLKLRHVMQFELKRIQREIGITFIYVTHDQEEALTMS
Mvan_3387|M.vanbaalenii_PYR-1 PSALLLDEPLGALDLKLRHVMQFELKRIQREVGITFIYVTHDQEEALTMS
MSMEG_0662|M.smegmatis_MC2_155 PRVLLLDEPLGALDAKLRKQLQLELRALQREVGITFVYVTHDQEEALTMS
Mb2419c|M.bovis_AF2122/97 PEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVA
Rv2397c|M.tuberculosis_H37Rv PEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVA
MMAR_3715|M.marinum_M PEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVA
MUL_3658|M.ulcerans_Agy99 PEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVA
MAV_1785|M.avium_104 PQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVA
TH_2424|M.thermoresistible__bu PEVLLLDEPFGALDAKVREDLRTWLRRLHEEVHVTTVLVTHDQSEALDVA
MAB_1655|M.abscessus_ATCC_1997 PQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVA
MLBr_01089|M.leprae_Br4923 PKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLG
* .:*:***:. ** *:* : : :: .: * : ***** **: :.
Mflv_3138|M.gilvum_PYR-GCK DRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTGRTN
Mvan_3387|M.vanbaalenii_PYR-1 DRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTGRAN
MSMEG_0662|M.smegmatis_MC2_155 DQIAVMAEGRVEQVGAPTEIYSAPATTYVAGFLG--AANIFDAELTEAAG
Mb2419c|M.bovis_AF2122/97 DRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVR---
Rv2397c|M.tuberculosis_H37Rv DRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNGSLVR---
MMAR_3715|M.marinum_M DRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFLG--AVSALNGALVR---
MUL_3658|M.ulcerans_Agy99 DRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLG--AVSALNGALVR---
MAV_1785|M.avium_104 DRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLG--AVSTLNGTLVR---
TH_2424|M.thermoresistible__bu DRIAVLNNGRIEQVGSPAEVYDSPANEFVMSFLG--AVSSLNGTLVR---
MAB_1655|M.abscessus_ATCC_1997 DRIAVLNKGRIEQVGSPEDLYDRPANSFVMSFLG--PVAKLNGILVR---
MLBr_01089|M.leprae_Br4923 DRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGL
*::.*: * ::*:*:* ::*. *.. :* .*:* . .
Mflv_3138|M.gilvum_PYR-GCK RDFVEIDVLGSTLKARPGETTIEPGGHATLMVRPERVRVSMDAPTGDVAG
Mvan_3387|M.vanbaalenii_PYR-1 RDYVEVDVLGSTLKARPGETTIEPGGHATLMVRPERIRVSMDAPTGDVAA
MSMEG_0662|M.smegmatis_MC2_155 ATGGTAVCTAMSTRLSAWVDGAAAPGPAAIVIRPE--RITLQGPDEPVAA
Mb2419c|M.bovis_AF2122/97 -------------------------PHDIRVGRTPNMAVAAADGTAGSTG
Rv2397c|M.tuberculosis_H37Rv -------------------------PHDIRVGRTPNMAVAAADGTAGSTG
MMAR_3715|M.marinum_M -------------------------PHDIRVGRTPEMAVAAADGTGESTG
MUL_3658|M.ulcerans_Agy99 -------------------------PHDIRVGRTPEMAVAAADGTGESTG
MAV_1785|M.avium_104 -------------------------PHDIRVGRTPEMAVAAEDGTAESTG
TH_2424|M.thermoresistible__bu -------------------------PHDIWVGRHPELPTS--DSTLQATG
MAB_1655|M.abscessus_ATCC_1997 -------------------------PHDIRVGRNADLARAAAEGTGETTG
MLBr_01089|M.leprae_Br4923 TLPLGELNLSRDVQAMIG---QHPVPDRVIVGVRPEHLTDAKLIDAHQHG
: .
Mflv_3138|M.gilvum_PYR-GCK ----VRATVSDLTFQGPVVRLSLAAP------DDSTVIAHVGPEQDLP--
Mvan_3387|M.vanbaalenii_PYR-1 ----VRATVSDLTFQGPVVRLSLAAP------DDSTVIAHVGPEQDLP--
MSMEG_0662|M.smegmatis_MC2_155 GSNVITGTVSHVVYLGASTQVHVDVG------EANSLVVEVPNHAGPQSV
Mb2419c|M.bovis_AF2122/97 ---VLRAVVDRVVVLGFEVRVELTSA------ATGGAFTAQITRGDAEAL
Rv2397c|M.tuberculosis_H37Rv ---VLRAVVDRVVVLGFEVRVELTSA------ATGGAFTAQITRGDAEAL
MMAR_3715|M.marinum_M ---VTRAVVDRIVVLGFEVRVELTSA------ATGGAFTAQITRGDAEAL
MUL_3658|M.ulcerans_Agy99 ---VTRAVVDRIVVLGFEVRVELTSA------ATGGAFTAQITRGDAEAL
MAV_1785|M.avium_104 ---VARAIVDRVVKLGFEVRVELTSA------ATGGPFTAQITRGDAEAL
TH_2424|M.thermoresistible__bu ---VVRARIDRVVMLGFEVRLELTSA------TNNAPFTAQITRGDAEAL
MAB_1655|M.abscessus_ATCC_1997 ---VTKATVDRVVYLGFEVRVELTSA------ATGEQFTAQITRGDAEAL
MLBr_01089|M.leprae_Br4923 TVLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQLDELASELEVRENQFV
:. : * : . ..
Mflv_3138|M.gilvum_PYR-GCK LLRPGDEVYVSWAPDASLVLPGADIPTTED----LEEMLDDS-----
Mvan_3387|M.vanbaalenii_PYR-1 LLRPGDDVFVSWAPDASLVLPGADIPTTED----LEEMLDDS-----
MSMEG_0662|M.smegmatis_MC2_155 SQQAGARVHCVCTPDAVRVLTRSPVAVIADPVVEPETALSAH-----
Mb2419c|M.bovis_AF2122/97 ALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv ALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M ALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 ALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 ALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA------
TH_2424|M.thermoresistible__bu GLRSGDTVYVRATRVP----------ALPTGDVDERVAAR-------
MAB_1655|M.abscessus_ATCC_1997 GLREGDPVYVRVTRVP---------------DVGELAEVAS------
MLBr_01089|M.leprae_Br4923 ARVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSAPTDA----
.