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VIEIDHVTKSFGDYVAVADADFSIASGEFFSMLGPSGCGKTTTLRMIAGFETPTEGAIRLEGADVSRTPP NKRNVNTVFQHYALFPHMTVWDNVAYGPRSKKLGKGEIRKRVDELLDIVRLTDFAERKPAQLSGGQQQRV ALARALVNYPSALLLDEPLGALDLKLRHVMQFELKRIQREVGITFIYVTHDQEEALTMSDRIAVMNAGNV EQIGTPTEIYDRPATVFVASFIGQANLWAGRQTGRANRDYVEVDVLGSTLKARPGETTIEPGGHATLMVR PERIRVSMDAPTGDVAAVRATVSDLTFQGPVVRLSLAAPDDSTVIAHVGPEQDLPLLRPGDDVFVSWAPD ASLVLPGADIPTTEDLEEMLDDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3387 | - | - | 100% (373) | spermidine/putrescine ABC transporter ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_5739 | - | 4e-72 | 42.78% (353) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 5e-68 | 52.59% (232) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-67 | 41.62% (346) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3138 | - | 0.0 | 95.71% (373) | spermidine/putrescine ABC transporter ATPase subunit |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-67 | 41.62% (346) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 8e-66 | 51.50% (233) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1655 | - | 9e-70 | 41.69% (355) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 1e-67 | 53.45% (232) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1377 | sugC | 5e-67 | 53.22% (233) | ABC transporter, ATP-binding protein SugC |
| M. smegmatis MC2 155 | MSMEG_3281 | - | 0.0 | 86.60% (373) | spermidine/putrescine ABC transporter ATP-binding subunit |
| M. thermoresistible (build 8) | TH_2424 | - | 9e-66 | 42.07% (347) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-67 | 53.02% (232) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3387|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3138|M.gilvum_PYR-GCK MRNRLRRTAESAIVYPQPGGSIEEDGALT--RAHTATGHGIGQ-GAASTK
MSMEG_3281|M.smegmatis_MC2_155 ----MRTSAESAKVYPQPLRLHLRRTTLTGPDTTAAVDHSAGQSGEPRKS
Mb2419c|M.bovis_AF2122/97 --------------------------------------------MT----
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------MT----
MMAR_3715|M.marinum_M --------------------------------------MKKETSLTGPGT
MUL_3658|M.ulcerans_Agy99 --------------------------------------------MTGPGT
TH_2424|M.thermoresistible__bu --------------------------------------------MT----
MAB_1655|M.abscessus_ATCC_1997 --------------------------------------------MT----
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
MAV_1377|M.avium_104 --------------------------------------------------
Mvan_3387|M.vanbaalenii_PYR-1 ---MIEIDHVTKSFGD-YVAVADADFSIASGEFFSMLGPSGCGKTTTLRM
Mflv_3138|M.gilvum_PYR-GCK GGPVIEIDHVTKRFGD-YLAVSDADFSIASGEFFSMLGPSGCGKTTTLRM
MSMEG_3281|M.smegmatis_MC2_155 GAPVIEIDHVTKRFAD-YVAVADADFSIAQGEFFSMLGPSGCGKTTTLRM
Mb2419c|M.bovis_AF2122/97 --YAIVVADATKRYGD-FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRT
Rv2397c|M.tuberculosis_H37Rv --YAIVVADATKRYGD-FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRT
MMAR_3715|M.marinum_M GGHAIVVRDAFKQYGD-FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRT
MUL_3658|M.ulcerans_Agy99 GGHAIVVRDAFKQYGD-FVALDHVDFVVPAGSLTALLGPSGSGKSTLLRT
TH_2424|M.thermoresistible__bu --DAITVRGANKRYGD-FAALDNVDFAVPAGSLTALLGPSGSGKSTLLRA
MAB_1655|M.abscessus_ATCC_1997 AENTITVRGANKHYGD-FAALDNIDFDVPSGSLTALLGPSGSGKSTLLRS
MLBr_01089|M.leprae_Br4923 -MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNM
MAV_1377|M.avium_104 -MAEIVLDHVSKSYPDGATAVRDLNLTIADGEFLILVGPSGCGKTTTLNM
* : . * : : *: . .: :. *.: ::****.**:* *.
Mvan_3387|M.vanbaalenii_PYR-1 IAGFETPTEGAIRLEGADVSRTPPNKRNVNTVFQHYALFPHMTVWDNVAY
Mflv_3138|M.gilvum_PYR-GCK IAGFETPSEGAIRLEGADVSKTPPNKRNVNTVFQHYALFPHMTVWDNVAY
MSMEG_3281|M.smegmatis_MC2_155 IAGFESPTEGAIRLEGVDVSRVPPHKRNVNTVFQHYALFPHMTVWDNVAY
Mb2419c|M.bovis_AF2122/97 IAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
Rv2397c|M.tuberculosis_H37Rv IAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
MMAR_3715|M.marinum_M IAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAY
MUL_3658|M.ulcerans_Agy99 IAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAY
TH_2424|M.thermoresistible__bu IAGLDRPDTGTITINGRDVTDVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
MAB_1655|M.abscessus_ATCC_1997 IAGLDNPDSGTITINGRDVTGVPPQRRDIGFVFQHYAAFKHLTVWENVAF
MLBr_01089|M.leprae_Br4923 IAGLEDISSGELRIDGDRVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAF
MAV_1377|M.avium_104 IAGLEDISSGELRIGGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAF
***:: * : : * *. .*: *.: *** ** : *:** :*:*:
Mvan_3387|M.vanbaalenii_PYR-1 GPRSKKLGKGEIRKRVDELLDIVRLTDFAERKPAQLSGGQQQRVALARAL
Mflv_3138|M.gilvum_PYR-GCK GPRSKKLDKGEIRKRVDELLEIVRLSDFAERKPAQLSGGQQQRVALARAL
MSMEG_3281|M.smegmatis_MC2_155 GPRSAKKDKAEIKRSVDELLEIVKLSDFAKRKPAQLSGGQQQRVALARAL
Mb2419c|M.bovis_AF2122/97 GLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARAL
Rv2397c|M.tuberculosis_H37Rv GLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARAL
MMAR_3715|M.marinum_M GLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARAL
MUL_3658|M.ulcerans_Agy99 GLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARAL
TH_2424|M.thermoresistible__bu GLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQLSGGQRQRMALARAL
MAB_1655|M.abscessus_ATCC_1997 GLKIRKKPKAEIKKKVDDLLEVVGLSGFHTRYPAQLSGGQRQRMALARAL
MLBr_01089|M.leprae_Br4923 PLMLAKVKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAI
MAV_1377|M.avium_104 PLTLAKMKKPEIAQKVAETAKILDLTDFLDRKPSQLSGGQRQRVAMGRAI
: * ** * : .:: *:.: * * ******:**:*:.**:
Mvan_3387|M.vanbaalenii_PYR-1 VNYPSALLLDEPLGALDLKLRHVMQFELKRIQREVGITFIYVTHDQEEAL
Mflv_3138|M.gilvum_PYR-GCK VNYPSALLLDEPLGALDLKLRHVMQFELKRIQREIGITFIYVTHDQEEAL
MSMEG_3281|M.smegmatis_MC2_155 VNYPSALLLDEPLGALDLKLRHAMQFELKRIQREVGITFIYVTHDQEEAL
Mb2419c|M.bovis_AF2122/97 AVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEAL
Rv2397c|M.tuberculosis_H37Rv AVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEAL
MMAR_3715|M.marinum_M AVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
MUL_3658|M.ulcerans_Agy99 AVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
TH_2424|M.thermoresistible__bu AVDPEVLLLDEPFGALDAKVREDLRTWLRRLHEEVHVTTVLVTHDQSEAL
MAB_1655|M.abscessus_ATCC_1997 AVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
MLBr_01089|M.leprae_Br4923 VRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAM
MAV_1377|M.avium_104 VRHPKAFLMDEPLSNLDAKLRVQMRGEIARLQKRLGTTTVYVTHDQTEAM
. *..:*:***:. ** *:* : : *:: .: * : ***** **:
Mvan_3387|M.vanbaalenii_PYR-1 TMSDRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTG
Mflv_3138|M.gilvum_PYR-GCK TMSDRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTG
MSMEG_3281|M.smegmatis_MC2_155 TMSDRIAVMNAGNVEQIGTPTEIYDKPATVFVANFIG--QANLWPGRQTE
Mb2419c|M.bovis_AF2122/97 DVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNG----
Rv2397c|M.tuberculosis_H37Rv DVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNG----
MMAR_3715|M.marinum_M DVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFLG--AVSALNG----
MUL_3658|M.ulcerans_Agy99 DVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLG--AVSALNG----
TH_2424|M.thermoresistible__bu DVADRIAVLNNGRIEQVGSPAEVYDSPANEFVMSFLG--AVSSLNG----
MAB_1655|M.abscessus_ATCC_1997 DVADRIAVLNKGRIEQVGSPEDLYDRPANSFVMSFLG--PVAKLNG----
MLBr_01089|M.leprae_Br4923 TLGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTP
MAV_1377|M.avium_104 TLGDRVVVMHSGVAQQIGTPDELYENPANLFVAGFIGSPAMNFFPATLTP
:.**:.*:. * :*:*:* ::*: *.. ** .*:* .
Mvan_3387|M.vanbaalenii_PYR-1 RANRDYVEVDVLGSTLKARPGETTIEPGGHATLMVRPERIRVSMDAPTGD
Mflv_3138|M.gilvum_PYR-GCK RTNRDFVEIDVLGSTLKARPGETTIEPGGHATLMVRPERVRVSMDAPTGD
MSMEG_3281|M.smegmatis_MC2_155 RTAGDYVEVEVLGTKLRAKPGDTAIEAGGHATLMIRPERVRVSIDAPTGD
Mb2419c|M.bovis_AF2122/97 ---------------SLVRPHDIRVGR--------TPNMAVAAADGTAGS
Rv2397c|M.tuberculosis_H37Rv ---------------SLVRPHDIRVGR--------TPNMAVAAADGTAGS
MMAR_3715|M.marinum_M ---------------ALVRPHDIRVGR--------TPEMAVAAADGTGES
MUL_3658|M.ulcerans_Agy99 ---------------ALVRPHDIRVGR--------TPEMAVAAADGTGES
TH_2424|M.thermoresistible__bu ---------------TLVRPHDIWVGR--------HPELPTS--DSTLQA
MAB_1655|M.abscessus_ATCC_1997 ---------------ILVRPHDIRVGR--------NADLARAAAEGTGET
MLBr_01089|M.leprae_Br4923 NG-----LTLPLGELNLSRDVQAMIGQHP------VPDRVIVGVRPEHLT
MAV_1377|M.avium_104 IG-----LKVPFGEVMLTPEVQQVIAEHP------EPDNVIVGARPEHLS
: : .:
Mvan_3387|M.vanbaalenii_PYR-1 VAAVRATVSDLTFQGPVVRLSLAAPDD---------STVIAHVGP-EQDL
Mflv_3138|M.gilvum_PYR-GCK VAGVRATVSDLTFQGPVVRLSLAAPDD---------STVIAHVGP-EQDL
MSMEG_3281|M.smegmatis_MC2_155 VATVPATVTDLTFQGPVVRLSLAAPDD---------STIVAHVGA-EQNL
Mb2419c|M.bovis_AF2122/97 TGVLRAVVDRVVVLGFEVRVELTSAATG--------GAFTAQITRGDAEA
Rv2397c|M.tuberculosis_H37Rv TGVLRAVVDRVVVLGFEVRVELTSAATG--------GAFTAQITRGDAEA
MMAR_3715|M.marinum_M TGVTRAVVDRIVVLGFEVRVELTSAATG--------GAFTAQITRGDAEA
MUL_3658|M.ulcerans_Agy99 TGVTRAVVDRIVVLGFEVRVELTSAATG--------GAFTAQITRGDAEA
TH_2424|M.thermoresistible__bu TGVVRARIDRVVMLGFEVRLELTSATNN--------APFTAQITRGDAEA
MAB_1655|M.abscessus_ATCC_1997 TGVTKATVDRVVYLGFEVRVELTSAATG--------EQFTAQITRGDAEA
MLBr_01089|M.leprae_Br4923 DAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQLDELA
MAV_1377|M.avium_104 DAALIDGYQRIRALTFEVKVDMVESLGADKYVYFSTAAWAAHSTQLDELA
. *::.:. . . :
Mvan_3387|M.vanbaalenii_PYR-1 PLLRPGDDVFVSWAPDASLVLPGADIPTTEDLEEMLDDS-----------
Mflv_3138|M.gilvum_PYR-GCK PLLRPGDEVYVSWAPDASLVLPGADIPTTEDLEEMLDDS-----------
MSMEG_3281|M.smegmatis_MC2_155 PLLRPGDRVHVSWSPDASRVLPAADIPTTEDLEDMLDDS-----------
Mb2419c|M.bovis_AF2122/97 LALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----------
Rv2397c|M.tuberculosis_H37Rv LALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----------
MMAR_3715|M.marinum_M LALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGGQ-----
MUL_3658|M.ulcerans_Agy99 LALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ-----
TH_2424|M.thermoresistible__bu LGLRSGDTVYVRATRVPALP--TGDVDERVAAR-----------------
MAB_1655|M.abscessus_ATCC_1997 LGLREGDPVYVRVTRVPDVG----ELAEVAS-------------------
MLBr_01089|M.leprae_Br4923 SELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSA
MAV_1377|M.avium_104 AEADAHENQFVARVPAESKAAIGQTVELALDTTKLMVFDADSGVNLTV-A
: .* :
Mvan_3387|M.vanbaalenii_PYR-1 -----
Mflv_3138|M.gilvum_PYR-GCK -----
MSMEG_3281|M.smegmatis_MC2_155 -----
Mb2419c|M.bovis_AF2122/97 -----
Rv2397c|M.tuberculosis_H37Rv -----
MMAR_3715|M.marinum_M -----
MUL_3658|M.ulcerans_Agy99 -----
TH_2424|M.thermoresistible__bu -----
MAB_1655|M.abscessus_ATCC_1997 -----
MLBr_01089|M.leprae_Br4923 PTDA-
MAV_1377|M.avium_104 PSDSP