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NPVAGDDVVVIARDVTKRFGDTLALDHVSLDVHRSELLVLLGLSGSGKSTLLRCLNGLHPVTSGTVDVGG TRVDQASGAQLRALRRRVGFVFQHFNLVGRLSCLENVLIGGLGRLRLPRYGALTYPRHMRAEALAHLDRV GLADYADRRADTLSGGQQQRVAIARTLMQKPALLLADEPVASLDPENAGVVMDLLFRVCIEEKLTVVCTL HQVDLALGWAHRLVGLQGGRKVLDRPAVGMTRDDVMAVYQRVEPAVTPARRV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0647 | phnC | - | 100% (263) | phosphonate ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_1614 | - | 4e-41 | 42.44% (238) | glutamine transport ATP-binding protein GlnQ |
| M. smegmatis MC2 155 | MSMEG_2728 | - | 2e-36 | 41.10% (236) | glutamate transport ATP-binding protein GluA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1012 | - | 3e-32 | 38.64% (220) | adhesion component transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_1231 | - | 8e-35 | 43.26% (215) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0986 | - | 2e-32 | 38.94% (226) | adhesion component transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00669 | ftsE | 1e-29 | 38.07% (218) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4237c | - | 5e-37 | 40.91% (242) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 2e-28 | 37.29% (236) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_4425 | - | 4e-31 | 41.82% (220) | ABC-type transporter, ATPase component |
| M. thermoresistible (build 8) | TH_4568 | - | 1e-120 | 81.44% (264) | PUTATIVE phosphonate ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-29 | 38.46% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2905 | - | 1e-126 | 87.26% (259) | phosphonate ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0647|M.smegmatis_MC2_155 -------MNPVAGDDVVVIARDVTKRFGDTLALDHVSLDVHRSELLVLLG
Mvan_2905|M.vanbaalenii_PYR-1 MPASRPADHDVAGDDVVIAAHNVTKRFGNTLALDDVSLEVRRSELLVLLG
TH_4568|M.thermoresistible__bu --LTAPPVEPVAGDDLVIAVRDATKRFGGTVALDGVSLDVHRSEFVVLLG
Mb1012|M.bovis_AF2122/97 -------MNRQPIVQLSNLSWTFREGETRRQVLDHITFDFEPGEFVALLG
Rv0986|M.tuberculosis_H37Rv -------MNRQPIVQLSNLSWTFREGETRRQVLDHITFDFEPGEFVALLG
MAV_4425|M.avium_104 -------MT----IEMAGVVREYRVGGQPVRALDRISLQLAGGQFVAVVG
MLBr_00669|M.leprae_Br4923 ------------MITLDHVSKKYKS--LARPALDNVNVKIDKGEFVFLIG
Mflv_1231|M.gilvum_PYR-GCK -----------MTTDTCVAAREVHKSFGPLEVLKGVSFTVARGSATAIIG
MAB_4237c|M.abscessus_ATCC_199 -----------MST---IEVRGVRKSYGQVTALRDVNLTVHQGEVTVIIG
MMAR_3715|M.marinum_M -MKKETSLTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALLG
MUL_3658|M.ulcerans_Agy99 -------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTALLG
.* : . . .. ::*
MSMEG_0647|M.smegmatis_MC2_155 LSGSGKSTLLRCLNGLHPVTSGTVDVGGTRVDQAS--------GAQLRAL
Mvan_2905|M.vanbaalenii_PYR-1 LSGSGKSTLLRCLNGLHPVTSGTVEVDGTRVDGAS--------KAQLRAL
TH_4568|M.thermoresistible__bu LSGSGKSTLLRCLNGLHRVTSGTVEVGGVRVNTAS--------RRELRRL
Mb1012|M.bovis_AF2122/97 QSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKT--------ERDRTLF
Rv0986|M.tuberculosis_H37Rv QSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKT--------ERDRTLF
MAV_4425|M.avium_104 PSGAGKSTLLHLLGALDSPDSGSILFDGEEIGRLG--------DEAQSRF
MLBr_00669|M.leprae_Br4923 PSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLP--------GRHIPRL
Mflv_1231|M.gilvum_PYR-GCK PSGSGKTTLLRTLNALDVADSGVITVGDVEIDFAR------PVSKDQLRR
MAB_4237c|M.abscessus_ATCC_199 PSGSGKSTLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERAILR
MMAR_3715|M.marinum_M PSGSGKSTLLRTIAGLDQPDSGNITINGRDV--------------TRVPP
MUL_3658|M.ulcerans_Agy99 PSGSGKSTLLRTIAGLDQPDSGNITINGRDV--------------TRVPP
**:**:*::. : . :* : .. :
MSMEG_0647|M.smegmatis_MC2_155 R-RRVGFVFQHFNLVGRLSCLENVLIGGLGRLRLPRYGALTYPRHMRAEA
Mvan_2905|M.vanbaalenii_PYR-1 R-RNVGFVFQHFNLVGRLSCLENVLIGGLGQLTFPRYGALTYPKRMRTEA
TH_4568|M.thermoresistible__bu R-RRVGFVFQQFNLVGRLSCLENVLIGGLGRLTLPRYGALTYPRRMRTEA
Mb1012|M.bovis_AF2122/97 RRDQIGIVFQFFNLIPTLTVLENITL--------PQELAGVSQRKAAVVA
Rv0986|M.tuberculosis_H37Rv RRDQIGIVFQFFNLIPTLTVLENITL--------PQELAGVSQRKAAVVA
MAV_4425|M.avium_104 RHRRVGFVFQFFNLLPTLSAWENVAI--------PRLLDGVRLGRARPDA
MLBr_00669|M.leprae_Br4923 R-QVIGCVFQDFRLLQQKTVYENVAF--------ALEVIGRRSDAINQVV
Mflv_1231|M.gilvum_PYR-GCK YRAQSGFVFQAHNLFPHMTVLQNVTEGP-------VVAQRRPRDEVEAEA
MAB_4237c|M.abscessus_ATCC_199 QRSQVGFVFQNFNLFPHLTVLENVIEAP-------LAARRAPRAELEAEA
MMAR_3715|M.marinum_M QRRGIGFVFQHYAAFKHLTVRDNVAYG--------LKIRKRPKAEIRDKV
MUL_3658|M.ulcerans_Agy99 QRRGIGFVFQHYAAFKHLTVRDNVAYG--------LKIRKRPKAEIRDKV
* *** . . : :*: .
MSMEG_0647|M.smegmatis_MC2_155 LAHLDRVGLADYADRRADTLSGGQQQRVAIARTLMQKPALLLADEPVASL
Mvan_2905|M.vanbaalenii_PYR-1 LAHLDRVGLADFAERRADTLSGGQQQRVAIARTLMQAPALLLADEPVASL
TH_4568|M.thermoresistible__bu LEHLDRVGLAGLAEQRADTLSGGQQQRVAIARTLMQRPSLLLADEPVASL
Mb1012|M.bovis_AF2122/97 RDLLEKVGMADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNL
Rv0986|M.tuberculosis_H37Rv RDLLEKVGMADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNL
MAV_4425|M.avium_104 LRLLERVGLGNRTEHRPAELSGGQMQRVAVARALMMDPPLILADEPTGNL
MLBr_00669|M.leprae_Br4923 PDVLETVGLSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNL
Mflv_1231|M.gilvum_PYR-GCK LELLDQVGLKDKRDAYPFQLSGGQQQRVGIARALALKPKVVLFDEPTSAL
MAB_4237c|M.abscessus_ATCC_199 TRLLERVGVADKAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSAL
MMAR_3715|M.marinum_M DNLLEVVGLSGFHGRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGAL
MUL_3658|M.ulcerans_Agy99 DNLLEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGAL
*: **: . . ****: **:.::*:: * ::* *** . *
MSMEG_0647|M.smegmatis_MC2_155 DPENAGVVMDLLFRVCIEEK--LTVVCTLHQVDLALGWAHRLVGLQGGRK
Mvan_2905|M.vanbaalenii_PYR-1 DPENAGLVMDLLFRVCIEEK--LTVVCTLHQVDLALGWAHRLVGLRNGRK
TH_4568|M.thermoresistible__bu DPENAGVVMDLLFQVCMEQK--LTVVCTLHQIDLALGWAHRLVGLRAGRK
Mb1012|M.bovis_AF2122/97 DSDTGDKVLDVLLDLTRQAG--KTLIMATHSPSMTQHA-DRVVNLQGGRL
Rv0986|M.tuberculosis_H37Rv DSDTGDKVLDVLLDLTRQAG--KTLIMATHSPSMTQHA-DRVVNLQGGRL
MAV_4425|M.avium_104 DSSTGAAILELLAEVAHEGGGDRLVVMVTHNSDAAAAT-DRVITLQDGRV
MLBr_00669|M.leprae_Br4923 DPDTSKDIMDLLERINRTGT---TVLMATHDHHIVDSMRQRVVELSLGRL
Mflv_1231|M.gilvum_PYR-GCK DPELVGEVLGVIRDLAVQG---WTLVVVTHEIQFARGVSDQVLFTDQGVI
MAB_4237c|M.abscessus_ATCC_199 DPELVTEVLDVIAQLARDG---ATLVIVTHEIGLAREIADTVVFMDRGAI
MMAR_3715|M.marinum_M DAKVREDLRAWLRRLHDEVH--VTTVLVTHDQAEALDVADRIAVLNSGRI
MUL_3658|M.ulcerans_Agy99 DAKVREDLRAWLRRLHDEVH--VTTVLVTHDQAEALDVADRIAVLNSGRI
*.. : : : : . *. . . : *
MSMEG_0647|M.smegmatis_MC2_155 VLDRPAVGMTRDDVMAVYQRVEPAVTPARRV-------------------
Mvan_2905|M.vanbaalenii_PYR-1 VLDRPAVGLTRDEVMGIYQRVDPAVDSAPRSAVT----------------
TH_4568|M.thermoresistible__bu VLDRPAVGASHDDVLDIYRRVDPAVIGSPAGR------------------
Mb1012|M.bovis_AF2122/97 IPALNRENQTDQPASTILLPTSYE--------------------------
Rv0986|M.tuberculosis_H37Rv IPAVNRENQTDQPASTILLPTSYE--------------------------
MAV_4425|M.avium_104 G-------------SDVLAVAG----------------------------
MLBr_00669|M.leprae_Br4923 VR---------DEWCGIYGMDR----------------------------
Mflv_1231|M.gilvum_PYR-GCK LEQGSPAEVIGDPKEERTRQFLQRILNPL---------------------
MAB_4237c|M.abscessus_ATCC_199 VEQGPPKEVLDSPSHPRTASFLSKVLS-----------------------
MMAR_3715|M.marinum_M EQVGSPTEVYDAPANAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAA
MUL_3658|M.ulcerans_Agy99 EQVGSPTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAA
MSMEG_0647|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2905|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4568|M.thermoresistible__bu --------------------------------------------------
Mb1012|M.bovis_AF2122/97 --------------------------------------------------
Rv0986|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4425|M.avium_104 --------------------------------------------------
MLBr_00669|M.leprae_Br4923 --------------------------------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3715|M.marinum_M ADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEAL
MUL_3658|M.ulcerans_Agy99 ADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEAL
MSMEG_0647|M.smegmatis_MC2_155 --------------------------------------------
Mvan_2905|M.vanbaalenii_PYR-1 --------------------------------------------
TH_4568|M.thermoresistible__bu --------------------------------------------
Mb1012|M.bovis_AF2122/97 --------------------------------------------
Rv0986|M.tuberculosis_H37Rv --------------------------------------------
MAV_4425|M.avium_104 --------------------------------------------
MLBr_00669|M.leprae_Br4923 --------------------------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------
MMAR_3715|M.marinum_M ALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 ALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ