For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTDTCVAAREVHKSFGPLEVLKGVSFTVARGSATAIIGPSGSGKTTLLRTLNALDVADSGVITVGDVEID FARPVSKDQLRRYRAQSGFVFQAHNLFPHMTVLQNVTEGPVVAQRRPRDEVEAEALELLDQVGLKDKRDA YPFQLSGGQQQRVGIARALALKPKVVLFDEPTSALDPELVGEVLGVIRDLAVQGWTLVVVTHEIQFARGV SDQVLFTDQGVILEQGSPAEVIGDPKEERTRQFLQRILNPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1231 | - | - | 100% (252) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3581 | - | 5e-67 | 51.81% (249) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3968 | - | 5e-63 | 47.13% (244) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-38 | 39.58% (240) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-38 | 39.58% (240) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01122 | - | 1e-34 | 35.12% (242) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 3e-70 | 55.20% (250) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 7e-59 | 49.59% (244) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 2e-56 | 48.56% (243) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6309 | - | 1e-104 | 75.50% (249) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 4e-67 | 51.64% (244) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 6e-39 | 40.00% (240) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_5577 | - | 1e-119 | 85.20% (250) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv ----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
MUL_3658|M.ulcerans_Agy99 ----------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTA
Mflv_1231|M.gilvum_PYR-GCK -----------MTT---DTCVAAREVHKSFGPLEVLKGVSFTVARGSATA
Mvan_5577|M.vanbaalenii_PYR-1 -----------MSTPETENRVIAEDVRKSFDELQVLKGVSFTVPRGTATA
MSMEG_6309|M.smegmatis_MC2_155 -----------MTT-EPEYRIVAENVEKAFGDNKVLKGVSFKVARGSATT
MAB_4237c|M.abscessus_ATCC_199 -----------MST------IEVRGVRKSYGQVTALRDVNLTVHQGEVTV
MMAR_0060|M.marinum_M --------MTRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTAA
MAV_0058|M.avium_104 --------MS-NPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTVA
TH_1784|M.thermoresistible__bu MDSAGADVAVADPAAEAVPMISMRGVNKYFGSLHVLRDINLDVARGQVVV
MLBr_01122|M.leprae_Br4923 ------------MSPLLEVTDLAVTFETNGEPVTAVRGISYRINAGEVVA
.: :. * ..
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQPDTGTITIN---GRDVTRVPP--------
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQPDTGTITIN---GRDVTRVPP--------
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQPDSGNITIN---GRDVTRVPP--------
Mflv_1231|M.gilvum_PYR-GCK IIGPSGSGKTTLLRTLNALDVADSGVITVG---DVEIDFARP------VS
Mvan_5577|M.vanbaalenii_PYR-1 IIGPSGSGKTTLLRALNALDVPDAGVIRVG---DIEIDFGKT------VP
MSMEG_6309|M.smegmatis_MC2_155 ILGPSGSGKTTLLRALNALDVPDSGVIQVGGDDGVRIDFSER------IT
MAB_4237c|M.abscessus_ATCC_199 IIGPSGSGKSTLLRALNHLEKVDAGTIRID---GELIGYRQRGSVLYELP
MMAR_0060|M.marinum_M VIGPSGSGKSTLLRTLNRLHEPDSGDILLD---GRSVLRD----------
MAV_0058|M.avium_104 VIGPSGSGKSTLLRTLNRLYEPDRGDILLD---GRSVLHD----------
TH_1784|M.thermoresistible__bu VLGPSGSGKSTLCRTLNRLEPIDSGAISID---GVALPAEGR--------
MLBr_01122|M.leprae_Br4923 MVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLHNTELVGLAD--------
::* *****:: :: * . :
Mb2419c|M.bovis_AF2122/97 ------QRRGIGFVFQH--YAAFKHLTVRDNVAFG-LKIRKRP-KAEIKA
Rv2397c|M.tuberculosis_H37Rv ------QRRGIGFVFQH--YAAFKHLTVRDNVAFG-LKIRKRP-KAEIKA
MUL_3658|M.ulcerans_Agy99 ------QRRGIGFVFQH--YAAFKHLTVRDNVAYG-LKIRKRP-KAEIRD
Mflv_1231|M.gilvum_PYR-GCK KDQLRRYRAQSGFVFQA--HNLFPHMTVLQNVTEGPVVAQRRP-RDEVEA
Mvan_5577|M.vanbaalenii_PYR-1 RDQLRRYRAQSGFVFQS--HNLFPHKTVLQNVTEGPLVAQKRP-REQVEA
MSMEG_6309|M.smegmatis_MC2_155 RDTLRRYRAQSGFVFQS--HNLFPHKTVLQNITEGPIVAQGRP-RAEAET
MAB_4237c|M.abscessus_ATCC_199 ERAILRQRSQVGFVFQN--FNLFPHLTVLENVIEAPLAARRAP-RAELEA
MMAR_0060|M.marinum_M --NPNDLRQRIGMVFQH--FNLFPHRNVVDNVTLAPRKLRGLS-NEEARM
MAV_0058|M.avium_104 --DPDQLRQRIGMVFQH--FNLFPHRTVLDNVALAPRKLRRLP-AEAARE
TH_1784|M.thermoresistible__bu --ELARLRADVGMVFQQ--FNLFAHKTIVDNVALGPMKVRKTP-REQARA
MLBr_01122|M.leprae_Br4923 KTMSRFRGKAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHR
* *** .: ::: . : .
Mb2419c|M.bovis_AF2122/97 KVDNLLQVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
Rv2397c|M.tuberculosis_H37Rv KVDNLLQVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDE
MUL_3658|M.ulcerans_Agy99 KVDNLLEVVGLSG---FHGRYPDQLSGGQRQRMALARALAVDPEVLLLDE
Mflv_1231|M.gilvum_PYR-GCK EALELLDQVGLKD---KRDAYPFQLSGGQQQRVGIARALALKPKVVLFDE
Mvan_5577|M.vanbaalenii_PYR-1 EAVELLDQVGLKD---KRDQYPFQLSGGQQQRVGIARALALKPKVVLFDE
MSMEG_6309|M.smegmatis_MC2_155 DAVKLLEQVGLAD---KRDQYPYQLSGGQQQRVGIARALAMRPKVVLFDE
MAB_4237c|M.abscessus_ATCC_199 EATRLLERVGVAD---KAAQYPRRLSGGQQQRVAIARALALRPKVILFDE
MMAR_0060|M.marinum_M LALDQLDRVGLKH---KANARPDMLSGGQQQRVAIARALAMAPQVMFFDE
MAV_0058|M.avium_104 LALTQLDRVGLKH---KAGARPATLSGGQQQRVAIARALAMSPQVMFFDE
TH_1784|M.thermoresistible__bu EAMALLERVGVAD---QADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDE
MLBr_01122|M.leprae_Br4923 RAVELLELVGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDE
. *: **: * ****::**: :* ::* *.::: **
Mb2419c|M.bovis_AF2122/97 PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
Rv2397c|M.tuberculosis_H37Rv PFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK
MUL_3658|M.ulcerans_Agy99 PFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNS
Mflv_1231|M.gilvum_PYR-GCK PTSALDPELVGEVLGVIRDLAVQG-WTLVVVTHEIQFARGVSDQVLFTDQ
Mvan_5577|M.vanbaalenii_PYR-1 PTSALDPELVGEVLGVIRDLAVEG-WTLVVVTHEIQFARQVSDQVLFLDQ
MSMEG_6309|M.smegmatis_MC2_155 PTSALDPELVGEVLAVIKDLADAG-WTMVIVTHQIQFAKQVSDQVLFTDG
MAB_4237c|M.abscessus_ATCC_199 PTSALDPELVTEVLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMDR
MMAR_0060|M.marinum_M ATSALDPEMVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDH
MAV_0058|M.avium_104 ATSALDPEMVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDH
TH_1784|M.thermoresistible__bu PTSALDPEMINEVLAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSD
MLBr_01122|M.leprae_Br4923 PTTALDVTVQAQILEVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYA
. *** : : : :::**: . :* .
Mb2419c|M.bovis_AF2122/97 GRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMA
Rv2397c|M.tuberculosis_H37Rv GRIEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMA
MUL_3658|M.ulcerans_Agy99 GRIEQVGSPTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMA
Mflv_1231|M.gilvum_PYR-GCK GVILEQGSPAEVIGDPKEERTRQFLQRILNPL------------------
Mvan_5577|M.vanbaalenii_PYR-1 GVILERGAPAAVLGDPKEERTRQFLQRILNPL------------------
MSMEG_6309|M.smegmatis_MC2_155 GVILEQGTPAAVIDDPQHERTKQFLQRILNTL------------------
MAB_4237c|M.abscessus_ATCC_199 GAIVEQGPPKEVLDSPSHPRTASFLSKVLS--------------------
MMAR_0060|M.marinum_M GTVVEAGPPEQLFEAARTERLQRFLAQVL---------------------
MAV_0058|M.avium_104 GKVVESGPPEQIFEAAETERLQRFLSQVL---------------------
TH_1784|M.thermoresistible__bu GAIVEDAEPARFFEDPQTDRARDFLGKILHH-------------------
MLBr_01122|M.leprae_Br4923 GRVVESAQVSTLYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLA
* : : . . :* :
Mb2419c|M.bovis_AF2122/97 --------------------------VAAADGTAGSTGVLRAVVDRVVVL
Rv2397c|M.tuberculosis_H37Rv --------------------------VAAADGTAGSTGVLRAVVDRVVVL
MUL_3658|M.ulcerans_Agy99 --------------------------VAAADGTGESTGVTRAVVDRIVVL
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 GLQQECPFAPRCPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRSAAD
Mb2419c|M.bovis_AF2122/97 GFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG
Rv2397c|M.tuberculosis_H37Rv GFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG
MUL_3658|M.ulcerans_Agy99 GFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAGA
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 IYGINTDTRTSATSDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGV
Mb2419c|M.bovis_AF2122/97 VSGVDDAGVERVKVTST---------------------------------
Rv2397c|M.tuberculosis_H37Rv VSGVDDAGVERVKVTST---------------------------------
MUL_3658|M.ulcerans_Agy99 APAVPDDGAGSTPRAAQIGVGGQ---------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 SFELQQGRTLGIVGESGSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNR
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 ASRRSMRRNIQVVFQDPVASLDPRLPVFELIAEPLHANGFSKNYTQMRVA
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 ELLDIVGLRRDDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSAL
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3658|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5577|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6309|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 DVSIQAGIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVE
Mb2419c|M.bovis_AF2122/97 -----------------------------
Rv2397c|M.tuberculosis_H37Rv -----------------------------
MUL_3658|M.ulcerans_Agy99 -----------------------------
Mflv_1231|M.gilvum_PYR-GCK -----------------------------
Mvan_5577|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_6309|M.smegmatis_MC2_155 -----------------------------
MAB_4237c|M.abscessus_ATCC_199 -----------------------------
MMAR_0060|M.marinum_M -----------------------------
MAV_0058|M.avium_104 -----------------------------
TH_1784|M.thermoresistible__bu -----------------------------
MLBr_01122|M.leprae_Br4923 QGDSHDVFRNPQHDYTRRLLGAIPRPEVG