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MPGSIFEVRSSDPDALVRAGADIGNRAGRLQAQMDRQQAVIDDLRRGWNGASADAAIESAERSLQHMRRL HDSLTTLQSALQTGGADLAQQRDRIVNHVDQLHAQGWQVADDGTVSIRPGSVLDFFAKVSPVQRVMLEAL AARASAELKAMLAQFDATDVTVGAQIRDAVAGLTAHGPAPASPPPNNAKALVDRLAGMTPDERREFLAGL SPETVHEMVLADPETMGNTDGVPFETRIEANDINIRNALEEELAKPSPDQARVQQLQAMLTPIKDPAGSG KLVPRKFVAFSPDGNGRMIEMIGEIKPGIKGVGVVVPGTNTNLNGSGSNHTSAVELSKQSGSPVFLYMDG DFPQGLDKAADPAYAASMAPKLVSFGHEIDREVGIGAPDTPVTYIGHSYGGAIVGTAEQMGLRADRVLHA SSAGTGILSGDYTNPNPNVQRFSMTAPGDPISLVQSLPRDVAISSIPGVDSIPGIPHNTDGRIGNPLGGL PSATDPDNIPGVTRLDTGYYGAEGAHPNQVIVGPDGHGKYWDDYDSDAFKNMVAVISGGEATGYVERGIE TNYVDIDLGDDGDFRDEAADQAKAGAAPKAPRLPWDDNGTYERRQHPWDNPRVTDNPGLGPRVPVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0365 | - | - | 100% (626) | hypothetical protein MSMEG_0365 |
| M. smegmatis MC2 155 | MSMEG_1960 | - | 4e-14 | 28.74% (174) | hypothetical protein MSMEG_1960 |
| M. smegmatis MC2 155 | MSMEG_6381 | - | 1e-07 | 24.24% (491) | hypothetical protein MSMEG_6381 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2105 | - | 2e-11 | 22.16% (573) | hypothetical protein Mb2105 |
| M. gilvum PYR-GCK | Mflv_3088 | - | 6e-63 | 31.90% (558) | hypothetical protein Mflv_3088 |
| M. tuberculosis H37Rv | Rv2079 | - | 2e-11 | 22.16% (573) | hypothetical protein Rv2079 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0252 | - | 0.0 | 58.16% (643) | hypothetical protein MAB_0252 |
| M. marinum M | MMAR_0482 | - | 1e-09 | 29.03% (186) | hypothetical protein MMAR_0482 |
| M. avium 104 | MAV_1479 | - | 5e-11 | 25.36% (209) | hypothetical protein MAV_1479 |
| M. thermoresistible (build 8) | TH_4075 | - | 9e-40 | 30.37% (461) | PUTATIVE putative protein of unknown function DUF1023 |
| M. ulcerans Agy99 | MUL_1133 | - | 1e-06 | 31.20% (125) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_3447 | - | 1e-68 | 34.29% (560) | hypothetical protein Mvan_3447 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0365|M.smegmatis_MC2_155 --------------------------MPGSIFEVRSSDPDALVRAGADIG
MAB_0252|M.abscessus_ATCC_1997 --------------------------MRPTISQLRGWNLDALGKAADAAR
Mflv_3088|M.gilvum_PYR-GCK MGVGRLRGRRILPRRRRRSRRTVPPPVSPTVSAARRWRPDALLELAEQCD
Mvan_3447|M.vanbaalenii_PYR-1 --------------------------------MAQRWRPDALLQLAEGWD
MMAR_0482|M.marinum_M ----------------------MAASGIPDLSALLAWPTDHLTEAAAHWD
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 --------MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFH
Rv2079|M.tuberculosis_H37Rv --------MQLRHINIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFH
TH_4075|M.thermoresistible__bu -------------VMVTIPLVEAS-------------RPEELVSAAAKAG
MAV_1479|M.avium_104 --------------------------MPATLSQILAWSTEHLIEAAAYWT
MSMEG_0365|M.smegmatis_MC2_155 NRAGRLQAQMDRQQAVIDDLRRGWNGASADAAIESAERSLQHMRRLHDSL
MAB_0252|M.abscessus_ATCC_1997 DNARTLDASLDSCDRVFNDAS-GWYGKTHDAAKIKVDQELDHGREIRNVL
Mflv_3088|M.gilvum_PYR-GCK DAARRLCDHIDDSVTAADASRDYWTGAAADAARGAARGIAADAARAAHRL
Mvan_3447|M.vanbaalenii_PYR-1 SAARALGADVDGAVADSDRSLDYWTGAAADAARERARGIAADTAEVARRL
MMAR_0482|M.marinum_M NVGEHTYAVAHQLWR--DATSIDWSGHAAGALRAATHADLQTTSAAVDQL
MUL_1133|M.ulcerans_Agy99 -------------------------------MRAATHADLQTTSAAVDQL
Mb2105|M.bovis_AF2122/97 AAGRCTAEANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQS
Rv2079|M.tuberculosis_H37Rv AAGRYTAEANAAFEEARRRFEASWNRENGEHPINDSAEVQRVTAALGVQS
TH_4075|M.thermoresistible__bu AAAATLQAQIARQQSTLTTLRTSWQGTAADAALAKAAPTLQQLQLLHQSL
MAV_1479|M.avium_104 QTADRWEDGFLTMRN--QAQSITWRGAGGDALRERTQADLSVVSAKADLL
MSMEG_0365|M.smegmatis_MC2_155 TTLQSA---LQTGGADLAQQRDRIVNHVDQLHAQGWQVADDGTVSIRPGS
MAB_0252|M.abscessus_ATCC_1997 NRISDD---AEDAARTLKHAKEFTLQDVDGAVSEGFTVTDTGEVSHPDAK
Mflv_3088|M.gilvum_PYR-GCK VNASAA---ARDGATQIGAARDDAVGQVDDALEHGFLVADDGTVTVGADP
Mvan_3447|M.vanbaalenii_PYR-1 VTASVA---ARDGADQLAAARADVLAGLELAERDGLVVADDGSVTLADRP
MMAR_0482|M.marinum_M QEAARV---ARNGASDLYAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTG
MUL_1133|M.ulcerans_Agy99 QEAARV---ARNGASDLYAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTG
Mb2105|M.bovis_AF2122/97 LQLPKIGVDLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEH
Rv2079|M.tuberculosis_H37Rv LQLPKIGVDLENIAADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEH
TH_4075|M.thermoresistible__bu IDLQTS---LHTDGTALIGHRTALLETVSQLTALGWSVAPHGTVSVQAGS
MAV_1479|M.avium_104 RQAAGI---ARNGASDISAAQRRVVYGIEDAQNAGFTVGEDLSVTD-MRS
. . : : : : :
MSMEG_0365|M.smegmatis_MC2_155 VLDFFAKVSPVQRVMLEALAARASAELKAMLAQFDATDVTVGAQIRDAVA
MAB_0252|M.abscessus_ATCC_1997 KAQAAADHQRRIQSGLDELARLDDMYGKKLREAADDLES-----MRDGQH
Mflv_3088|M.gilvum_PYR-GCK DPLLVALAGGRDTLAADLLQLRADELSVRIPAALDRLGAADSDAAADLVR
Mvan_3447|M.vanbaalenii_PYR-1 APLLVLLAGGQEAVAVQMLEVRAAESSTRIRDALQRLGAADADAAADIAA
MMAR_0482|M.marinum_M GSAAQRAARQAQAQAFAGDLRQRAAQLVGLDAQVATKVTAAVAGIGSSFP
MUL_1133|M.ulcerans_Agy99 GSAAQRAARQAQAQAFAGDLPQRAAQLVGLDAQVATKVTAAVAGIGSSFP
Mb2105|M.bovis_AF2122/97 DPRLAAAERSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLA
Rv2079|M.tuberculosis_H37Rv DPRLAAAERSELDALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLA
TH_4075|M.thermoresistible__bu ALDQYARISPANAMRVQQLAATHTVVVARLLGEFDAADRRARGGITAAVA
MAV_1479|M.avium_104 TSPAERAARQAQAEAFAADIRLRAEQLDGADTKVAGQLTAATAGLGGSGF
MSMEG_0365|M.smegmatis_MC2_155 GLTAHGPA-------------PASPPPNNAKALVDRLAGMTPDERREFLA
MAB_0252|M.abscessus_ATCC_1997 DVTLPSGE-------------RVDP-----DALVDRVSKMSADERAAFLA
Mflv_3088|M.gilvum_PYR-GCK ALTDTDRP------VTPAPTVPAGAWPVPSGDVVDGWPAMSQDRIAAQVA
Mvan_3447|M.vanbaalenii_PYR-1 ALGAAHPQPAASTGQAPAATVPAGAWPVQAADVVDGWPRMSQDRISAQIA
MMAR_0482|M.marinum_M QIPAPAAP----------------PMGNPVRAVDNRTFKQNPPPAPVDPK
MUL_1133|M.ulcerans_Agy99 QIPAPAAP----------------PMGNPVRAVDNRTFKQNPPPAPVDPK
Mb2105|M.bovis_AF2122/97 MLRADGYD-----GAGLQGLDAPQSPVKLEEPIQIPPPGTGAPEVHRWWT
Rv2079|M.tuberculosis_H37Rv MLRADGYD-----GAGLQGLDAPQSPVKPEEPIQIPPPGTGAPEVHRWWT
TH_4075|M.thermoresistible__bu PLDGN--------VALVWSAFGPKPQTPARDGPQIPET-TDPVQIRDWWT
MAV_1479|M.avium_104 APASSPNS----------------------NHGAAAADRTTPGSNRNGVR
MSMEG_0365|M.smegmatis_MC2_155 GLSPETVHEMVLADPETMGNTDGVPFETRIEANDINIR------------
MAB_0252|M.abscessus_ATCC_1997 TLSPETVDAMVIANPEVMGNSDGIPFDTRIAANEINIR------------
Mflv_3088|M.gilvum_PYR-GCK AMTDDQRARLIAEFPHQVGNTDGVPWDMRVAANRTNIA------------
Mvan_3447|M.vanbaalenii_PYR-1 AMTPEQRGRLIAEFPQQVGNTDGIPWDMRVAANRLNIA------------
MMAR_0482|M.marinum_M DMTAEEARAAWADINSEIGKYNARCGRTFVLPTEQGAY------------
MUL_1133|M.ulcerans_Agy99 DMTAEEARAAWADINSEIGKYNARCGRTFVLPTEQGAY------------
Mb2105|M.bovis_AF2122/97 SLTSEERQRLIAEHPEQIGNLNGVPVSARSDANIAVMTRDLNRVRDIATR
Rv2079|M.tuberculosis_H37Rv SLTSEERQRLIAEHPEQIGNLNGVPVSARSDANIAVMTRDLNRVRDIATR
TH_4075|M.thermoresistible__bu SLTDEERERLLREHPEKLGNLNGIRVSDRSEANKTVMNNDIDRVQNRAAV
MAV_1479|M.avium_104 LVDFKQDGGPQPQPQPQPGAPQPAQQPSFLDQYKQALT------------
: . * :
MSMEG_0365|M.smegmatis_MC2_155 -----NALEEELAKPSPDQARVQQLQAMLTPIKD-----PAGSGK---LV
MAB_0252|M.abscessus_ATCC_1997 -----NALSDELQKQPPDQARVNQLQDMLKPMEDPLVTRPADAGPRDFMV
Mflv_3088|M.gilvum_PYR-GCK -----TAILAESAADAPSRRRIAFYRSLLGEVDD-----PSGDTR----I
Mvan_3447|M.vanbaalenii_PYR-1 -----GAILAETGSDDGSRRRIAFYRSLLGEIDD-----PAGGGR----I
MMAR_0482|M.marinum_M -----DACIADK--------------------------------------
MUL_1133|M.ulcerans_Agy99 -----DACIADK--------------------------------------
Mb2105|M.bovis_AF2122/97 YRTSVDDVLGDPAKYGLSAGDITRYRNADETKKGLDHNARNDPRNPSPVY
Rv2079|M.tuberculosis_H37Rv YRTSVDDVLGDPAKYGLSAGDITRYRNADETKKGLDHNARNDPRNPSPVY
TH_4075|M.thermoresistible__bu LGADIEEVLADPQRYNLTDTDVTRYRNAVKVREGLQRQAELT---DEPTY
MAV_1479|M.avium_104 --------------------------------------------------
MSMEG_0365|M.smegmatis_MC2_155 PRKFVAFSPDGNGRMIEMIGEIKPGIKGVGVVVPGTNTNLNG-------S
MAB_0252|M.abscessus_ATCC_1997 DRKYVMFSTEGNGRMIEMIGDIKPGVRGVGVIVPGTNTNLNG-------S
Mflv_3088|M.gilvum_PYR-GCK ARQILAFDP-GRASLVELHGDLGT-ARSVAVLVPGVNTTVEG-------S
Mvan_3447|M.vanbaalenii_PYR-1 PRRIIAFDP-GRASLIELNGDLAA-AHSVAVLVPGVNTTMEG-------S
MMAR_0482|M.marinum_M ------------GPLLDRQAAIRARLGQLGIPVEGEDPTHPG-------T
MUL_1133|M.ulcerans_Agy99 ------------GPLLDRQAVIRARLGQLGIPVEGEDPTHPG-------T
Mb2105|M.bovis_AF2122/97 LFAYDPMAFGGKGRAAIAIGNPDT-AKHTAVIVPGTSSSVKGGWLHDNHD
Rv2079|M.tuberculosis_H37Rv LFAYDPMAFGGKGRAAIAIGNPDT-AKHTAVIVPGTSSSVKGGWLHDNHD
TH_4075|M.thermoresistible__bu LFVYEPEEFGGQGRAAVAVGNPDT-AEDTVVLVPGTGNSVTDGWLAS--D
MAV_1479|M.avium_104 -------------SPGQPAQPAATPMPAFGPRPDPGPQPAPG--------
. .
MSMEG_0365|M.smegmatis_MC2_155 GSNHTSAVELSKQSGS--PVFLYMDGDFPQGLD------KAADPAYAASM
MAB_0252|M.abscessus_ATCC_1997 GSNHESAVKLAKESGS--PIFLYLGGDFPQGLD------KAADPSYAAAM
Mflv_3088|M.gilvum_PYR-GCK AANAATARRFVSGSDGRLAMITYLGGPFPQVHDPVTAVA-AADRRYALEM
Mvan_3447|M.vanbaalenii_PYR-1 AANTATARRFVSATDGDVAVITYLGGPFPQVHNPADVLFDAADARYALDM
MMAR_0482|M.marinum_M AEPPFPPPTRIN-------GLTEHGAQRVEGRD-----------GHGVND
MUL_1133|M.ulcerans_Agy99 AEPPFPPPTRIN-------GLTEHGAQRVEGRD-----------GHGVND
Mb2105|M.bovis_AF2122/97 DALNLFNQAKAADPNNPTAVIAWMGYDAPNDFTDP------RIATPMLAR
Rv2079|M.tuberculosis_H37Rv DALNLFNQAKAADPNNPTAVIAWMGYDAPNDFTDP------RIATPMLAR
TH_4075|M.thermoresistible__bu DITNVFKETNLANDGGPTAVVAWMGYDAPDSPIDP------RIAMTGLAR
MAV_1479|M.avium_104 PMPTVPPQPTFG---------QCVGGQVKANVG----------------K
.
MSMEG_0365|M.smegmatis_MC2_155 APKLVSFGHEIDREVGIGAPDTPVTYIGHSYGG--AIVGTAEQMGLRADR
MAB_0252|M.abscessus_ATCC_1997 APKLVDFGHEVDRAVGQNAPGTPVTYVGHSYGG--AIVGTAEQMGLRADR
Mflv_3088|M.gilvum_PYR-GCK APRLVAFSEDVARRVPD---SVLVTVVGHSYGG--SIVGTAETLGLTSDR
Mvan_3447|M.vanbaalenii_PYR-1 APRLVAFSEDVDRRVSD---GVAVTVIGHSYGG--SIVGTAETLGLTSDR
MMAR_0482|M.marinum_M NAMQDAVAHPIE----------PPQFMPDQYGGTWRYIGKDATVSLNENG
MUL_1133|M.ulcerans_Agy99 NAMQDAVAHPIE----------PPQFMPDQYGGTWRYIGKDATVSLNENG
Mb2105|M.bovis_AF2122/97 IGGAALAEDVNGLWVTHLGVGQNVTVLGHSYGS-TTVADAFALGGMHAND
Rv2079|M.tuberculosis_H37Rv IGGAALAEDVNGLWVTHLGVGQNVTVLGHSYGS-TTVADAFALGGMHAND
TH_4075|M.thermoresistible__bu EGGQLLASDVNALDVTSLGT-SHVTTIGHSYGS-TTVADAAAGYGMRVDD
MAV_1479|M.avium_104 DMVKAGFETGIKG-----------AIVGAAGGG----IATPEFAGAGALP
: *. .
MSMEG_0365|M.smegmatis_MC2_155 VLHASSAGTGILS---GDYTNPNPNVQRFSMTAPGDPISLVQSLPRDVAI
MAB_0252|M.abscessus_ATCC_1997 ILHASSAGTGILP---GGYTDPNPNVQRYSMTAPGDPIAIVQSLPRDVRL
Mflv_3088|M.gilvum_PYR-GCK TVFLAAAGAGVGVDDPGDWHNRNPHVQRYSMTAPGDFIELVQGIP-----
Mvan_3447|M.vanbaalenii_PYR-1 TVFLGAAGAGVGVDDTGDWHNRNPHVLRYSMTAPGDFIELVQGIP-----
MMAR_0482|M.marinum_M QVTTAWANS------RNGWRNP----------------------------
MUL_1133|M.ulcerans_Agy99 QVTTAWANS------RNGWRNP----------------------------
Mb2105|M.bovis_AF2122/97 AVLLGCPGTDLAHS--AASFHLD-GGRVYVGAASTDPISMLGQLDSLSQY
Rv2079|M.tuberculosis_H37Rv AVLLGCPGTDLAHS--AASFHLD-GGRVYVGAASTDPISMLGQLDSLSQY
TH_4075|M.thermoresistible__bu VVLIGSPGTDMAKS--AADFHLPEGGHVYVGSASTDPITGIGEAFG----
MAV_1479|M.avium_104 GAVLGFVGG------FAKGVEEAPVKAALEGAAECADVPIPGWMK-----
. . .
MSMEG_0365|M.smegmatis_MC2_155 SSIPGVDSIPGIPHNTDGRIGNPLGGLPSATDPDNIPGVTRLDTGYYGAE
MAB_0252|M.abscessus_ATCC_1997 SDVPGVDQIPGIPHNVEGRIGNPLGGLPSATDPDKIPGVTRLDTGYYGEF
Mflv_3088|M.gilvum_PYR-GCK -------------------------GGPHGADPDEMDGVIGLPTGFYDDG
Mvan_3447|M.vanbaalenii_PYR-1 -------------------------GGPHGVDPDEMNGVIPLRTGEYDDG
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 VNRGNLAGQL-----------QGLAVGLGTDPAGDGFGSVRFRAEVPNSD
Rv2079|M.tuberculosis_H37Rv VNRGNLAGQL-----------QGLAVGLGTDPAGDGFGSVRFRAEVPNSD
TH_4075|M.thermoresistible__bu --------------------------ALGNDPSMDGYGSTRFKAEVYGFN
MAV_1479|M.avium_104 --------------------------------------------------
MSMEG_0365|M.smegmatis_MC2_155 GAHPNQVIVGPDGHGKYWDDYDSDAFKNMVAVISGGEATGYVERGIETNY
MAB_0252|M.abscessus_ATCC_1997 GKHPNQVIVGPDGHGSYWDDPSSDAFHNIAAVIGGGEATGYVERGIQTNY
Mflv_3088|M.gilvum_PYR-GCK G-----LVAGWEAHSGMLNRP-SGAWRTILDVLTGDPGTLSSASSIPAGG
Mvan_3447|M.vanbaalenii_PYR-1 G-----PVAGWDAHSGMLNRP-SDSWRTILAIITGDCPTVRRAVAGAPT-
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 G--------INPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPR
Rv2079|M.tuberculosis_H37Rv G--------INPHDHSYYYHRGSEALRSMADIASGHGDALASDGMLAQPR
TH_4075|M.thermoresistible__bu A--------NVFADHSAYFEPGSESLYSIGDIASGNGDKLQEHGMTAQHR
MAV_1479|M.avium_104 --------------------------------------------------
MSMEG_0365|M.smegmatis_MC2_155 VDIDLGDDGDFRDEAADQAKAGAAPKAPRLPWDDNGTYERRQHPWDNPRV
MAB_0252|M.abscessus_ATCC_1997 VDINVGDDGNFRAEAWDQSRAAAGAQVPGLPWDDPGTIDRRHHPWDNPRV
Mflv_3088|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3447|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 HQPGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR-
Rv2079|M.tuberculosis_H37Rv HQPGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLHR-
TH_4075|M.thermoresistible__bu ----------GAG-------VLPDFVDPELFR--RATTGHHH--------
MAV_1479|M.avium_104 --------------------------------------------------
MSMEG_0365|M.smegmatis_MC2_155 TDNPGLGPRVPVR
MAB_0252|M.abscessus_ATCC_1997 TDHPEHGQKIQVK
Mflv_3088|M.gilvum_PYR-GCK -------------
Mvan_3447|M.vanbaalenii_PYR-1 -------------
MMAR_0482|M.marinum_M -------------
MUL_1133|M.ulcerans_Agy99 -------------
Mb2105|M.bovis_AF2122/97 -------------
Rv2079|M.tuberculosis_H37Rv -------------
TH_4075|M.thermoresistible__bu -------------
MAV_1479|M.avium_104 -------------