For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GVGRLRGRRILPRRRRRSRRTVPPPVSPTVSAARRWRPDALLELAEQCDDAARRLCDHIDDSVTAADASR DYWTGAAADAARGAARGIAADAARAAHRLVNASAAARDGATQIGAARDDAVGQVDDALEHGFLVADDGTV TVGADPDPLLVALAGGRDTLAADLLQLRADELSVRIPAALDRLGAADSDAAADLVRALTDTDRPVTPAPT VPAGAWPVPSGDVVDGWPAMSQDRIAAQVAAMTDDQRARLIAEFPHQVGNTDGVPWDMRVAANRTNIATA ILAESAADAPSRRRIAFYRSLLGEVDDPSGDTRIARQILAFDPGRASLVELHGDLGTARSVAVLVPGVNT TVEGSAANAATARRFVSGSDGRLAMITYLGGPFPQVHDPVTAVAAADRRYALEMAPRLVAFSEDVARRVP DSVLVTVVGHSYGGSIVGTAETLGLTSDRTVFLAAAGAGVGVDDPGDWHNRNPHVQRYSMTAPGDFIELV QGIPGGPHGADPDEMDGVIGLPTGFYDDGGLVAGWEAHSGMLNRPSGAWRTILDVLTGDPGTLSSASSIP AGG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3088 | - | - | 100% (564) | hypothetical protein Mflv_3088 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2105 | - | 2e-10 | 24.80% (496) | hypothetical protein Mb2105 |
M. tuberculosis H37Rv | Rv2079 | - | 2e-10 | 26.07% (422) | hypothetical protein Rv2079 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0252 | - | 5e-60 | 32.52% (575) | hypothetical protein MAB_0252 |
M. marinum M | MMAR_5468 | - | 6e-10 | 23.45% (533) | hypothetical protein MMAR_5468 |
M. avium 104 | MAV_1467 | - | 6e-10 | 25.22% (464) | hypothetical protein MAV_1467 |
M. smegmatis MC2 155 | MSMEG_0365 | - | 6e-63 | 31.90% (558) | hypothetical protein MSMEG_0365 |
M. thermoresistible (build 8) | TH_2466 | - | 2e-25 | 25.58% (516) | PUTATIVE putative protein of unknown function DUF1023 |
M. ulcerans Agy99 | MUL_1136 | - | 1e-06 | 32.74% (113) | hypothetical protein MUL_1136 |
M. vanbaalenii PYR-1 | Mvan_3447 | - | 0.0 | 71.37% (531) | hypothetical protein Mvan_3447 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3088|M.gilvum_PYR-GCK ---------------------------------------MGVGRLRGRRI Mvan_3447|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0252|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0365|M.smegmatis_MC2_155 -------------------------------------------------- Mb2105|M.bovis_AF2122/97 --------------------------------------------MQLRHI Rv2079|M.tuberculosis_H37Rv --------------------------------------------MQLRHI MMAR_5468|M.marinum_M MSSADAGYRPRFAVAAGATQRTSHAARINHLERLESRHDAVDGAMQLRYI MAV_1467|M.avium_104 -------------------------------------------------- TH_2466|M.thermoresistible__bu -------------------------------------------------- MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK LPRRRRRSRRTVPPPVSPTVSAARRWRPDALLELAEQCDDAARRLCDHID Mvan_3447|M.vanbaalenii_PYR-1 ---------------------MAQRWRPDALLQLAEGWDSAARALGADVD MAB_0252|M.abscessus_ATCC_1997 ---------------MRPTISQLRGWNLDALGKAADAARDNARTLDASLD MSMEG_0365|M.smegmatis_MC2_155 ---------------MPGSIFEVRSSDPDALVRAGADIGNRAGRLQAQMD Mb2105|M.bovis_AF2122/97 NIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRCTAEANAAFE Rv2079|M.tuberculosis_H37Rv NIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRYTAEANAAFE MMAR_5468|M.marinum_M SIPLLIAEAGGDPWAINQSLQLGRPAQISDLATAFHDAGRSTTEADTAFE MAV_1467|M.avium_104 -------------------------MQISNLANAFHAAGRSTAEADTTFA TH_2466|M.thermoresistible__bu ------------VWVMSATISLVEAADPQGLTAAAAQLQTKXTHLDTIIT MUL_1136|M.ulcerans_Agy99 ---------------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFL * . Mflv_3088|M.gilvum_PYR-GCK DSVTAADASRDYWTGAAADAARGAARGIAADAARAAHRLVNASAAARDGA Mvan_3447|M.vanbaalenii_PYR-1 GAVADSDRSLDYWTGAAADAARERARGIAADTAEVARRLVTASVAARDGA MAB_0252|M.abscessus_ATCC_1997 SCDRVFNDAS-GWYGKTHDAAKIKVDQELDHGREIRNVLNRISDDAEDAA MSMEG_0365|M.smegmatis_MC2_155 RQQAVIDDLRRGWNGASADAAIESAERSLQHMRRLHDSLTTLQSALQTGG Mb2105|M.bovis_AF2122/97 EARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGVDLENIA Rv2079|M.tuberculosis_H37Rv EARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGVDLENIA MMAR_5468|M.marinum_M QARRRFETSWNRENGAHPINDSPQVQGLTTSLRSQAARLPEIGLQLDNIA MAV_1467|M.avium_104 QARSRFDAAWNHQDGDHPINDSAEVERVTKSLGAQSVQLPKIGADLENIA TH_2466|M.thermoresistible__bu AERSALAALAGGWEGTAADAALARGEQHLAQQEQLRTRLTSLQATLADAG MUL_1136|M.ulcerans_Agy99 QMRN--QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGA * * . Mflv_3088|M.gilvum_PYR-GCK TQIGAARDDAVGQVDDALEHGFLVADDGTVTVGADPD-PLLVALAGGRDT Mvan_3447|M.vanbaalenii_PYR-1 DQLAAARADVLAGLELAERDGLVVADDGSVTLADRPA-PLLVLLAGGQEA MAB_0252|M.abscessus_ATCC_1997 RTLKHAKEFTLQDVDGAVSEGFTVTDTGEVSHPDAKK-AQAAADHQRRIQ MSMEG_0365|M.smegmatis_MC2_155 ADLAQQRDRIVNHVDQLHAQGWQVADDGTVSIRPGSV-LDFFAKVSPVQR Mb2105|M.bovis_AF2122/97 ADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHD-PRLAAAERSELD Rv2079|M.tuberculosis_H37Rv ADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHD-PRLAAAERSELD MMAR_5468|M.marinum_M GGLAGAQRSATGQIVGLEAQLRDIDSEIGEVLALEHG-AQLTTADRLALE MAV_1467|M.avium_104 ASLAEAQKAAAGQIGTLEAQLKGLDEMIAEAVEIETTHPELSAADRDALN TH_2466|M.thermoresistible__bu ANLSALRTRILDVAAQARSLGGLVRDDGTVIALTSGG------------- MUL_1136|M.ulcerans_Agy99 GTIGIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSR------------- : : : . Mflv_3088|M.gilvum_PYR-GCK LAADLLQLRADELSVRIPAALDRLGAADSDAAADLVRALTDTDRP----- Mvan_3447|M.vanbaalenii_PYR-1 VAVQMLEVRAAESSTRIRDALQRLGAADADAAADIAAALGAAHPQPAAST MAB_0252|M.abscessus_ATCC_1997 SGLDELARLDDMYGKKLREAADDLES-----MRDGQHDVTLPSGE----- MSMEG_0365|M.smegmatis_MC2_155 VMLEALAARASAELKAMLAQFDATDVTVGAQIRDAVAGLTAHGPA----- Mb2105|M.bovis_AF2122/97 ALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYDG---- Rv2079|M.tuberculosis_H37Rv ALITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYDG---- MMAR_5468|M.marinum_M ALVCALEDQAVGGTQSAVSQLHSIRAGYAGLLHQALTSLSADGFDP---- MAV_1467|M.avium_104 GYITSLEDDAIRDTKAALAQLQATRDGYSNTLQKALGNLKSDGYDP---- TH_2466|M.thermoresistible__bu ---LMTPDVAAAYTTTLKTLLQTFDRVDQQSSQSVIQALGDGADTG---- MUL_1136|M.ulcerans_Agy99 ----------RSAEQAARQAQAQAQAQATDIRQRAVEPVPPPAPGR---- : Mflv_3088|M.gilvum_PYR-GCK -VTPAPTVPAGAWPVPSGDVVDGWPAMSQDRIAAQVAAMTDDQRARLIAE Mvan_3447|M.vanbaalenii_PYR-1 GQAPAATVPAGAWPVQAADVVDGWPRMSQDRISAQIAAMTPEQRGRLIAE MAB_0252|M.abscessus_ATCC_1997 --------RVDP-----DALVDRVSKMSADERAAFLATLSPETVDAMVIA MSMEG_0365|M.smegmatis_MC2_155 --------PASPPPNNAKALVDRLAGMTPDERREFLAGLSPETVHEMVLA Mb2105|M.bovis_AF2122/97 -AGLQGLDAPQSPVKLEEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIAE Rv2079|M.tuberculosis_H37Rv -AGLQGLDAPQSPVKPEEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIAE MMAR_5468|M.marinum_M -AAIQALDAPQSPAEPAEVIAIPAPTASAEEVKKWWDSLSPQRRGRLIDE MAV_1467|M.avium_104 -AGIRAQEGPLSPA--------PPLPDDPTQFTQVWNSLTQEQKD-AEYA TH_2466|M.thermoresistible__bu ---------AEAPPEPDIDDLKPPEGATDTEVNQWWDGLSEEDRQRLIHE MUL_1136|M.ulcerans_Agy99 -------LPPLTPGEMATPRLPAPPPQPPIRGGADLAPAEPPPVVRTPME . . Mflv_3088|M.gilvum_PYR-GCK FPHQVG-NTDGVPWDMRVAANRTNIATAILAESAADAPSRRRIAFYRSLL Mvan_3447|M.vanbaalenii_PYR-1 FPQQVG-NTDGIPWDMRVAANRLNIAGAILAETGSDDGSRRRIAFYRSLL MAB_0252|M.abscessus_ATCC_1997 NPEVMG-NSDGIPFDTRIAANEINIRNALSDELQKQPPDQARVNQLQDML MSMEG_0365|M.smegmatis_MC2_155 DPETMG-NTDGVPFETRIEANDINIRNALEEELAKPSPDQARVQQLQAML Mb2105|M.bovis_AF2122/97 HPEQIG-NLNGVPVSARSDANIAVMTRDLNRVRDIATRYRTSVDDVLGDP Rv2079|M.tuberculosis_H37Rv HPEQIG-NLNGVPVSARSDANIAVMTRDLNRVRDIATRYRTSVDDVLGDP MMAR_5468|M.marinum_M HPPELG-NLNGINAITRDLVNQAVMDDDITRVESVAMQRGVSADDIVNNP MAV_1467|M.avium_104 RDHFIG-NHPGMPFPDRDHYNRMHLPELQNANQADLDRLRAAHPDWANGK TH_2466|M.thermoresistible__bu RPEWIG-NLDGVPASARDQANRNRLEG-LRDDPGLTVEERDTIAAIDDAL MUL_1136|M.ulcerans_Agy99 PPARLGGPIAGGPVPPGSIPHPVQPPHSHHGPPVLGKDELPDLGEFNPG- :* * : Mflv_3088|M.gilvum_PYR-GCK GEVDD------------PSGDTR----IARQILAFDP------------- Mvan_3447|M.vanbaalenii_PYR-1 GEIDD------------PAGGGR----IPRRIIAFDP------------- MAB_0252|M.abscessus_ATCC_1997 KPMEDPLV-------TRPADAGPRDFMVDRKYVMFSTE------------ MSMEG_0365|M.smegmatis_MC2_155 TPIKD------------PAGSGK---LVPRKFVAFSPD------------ Mb2105|M.bovis_AF2122/97 AKYGLSAGDITR---YRNADETKKGLDHNARNDPRNPSPVYLFAYDPMA- Rv2079|M.tuberculosis_H37Rv AKYGLSAGDITR---YRNADETKKGLDHNARNDPRNPSPVYLFAYDPMA- MMAR_5468|M.marinum_M RKYGLSGSDVTR---YRNAIRTRDGLIYDREHATDDPRPVMLWAYDPLA- MAV_1467|M.avium_104 TPFLKTNEYLDWRRQWDAANRARDGYSKVKNEMGPPPDKVQPGEIPKYLG TH_2466|M.thermoresistible__bu E-------------------------GEERQLLVLDFDG----------- MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK ---GRASLVELHGDLGT-ARSVAVLVPGVNTTVEG--------------- Mvan_3447|M.vanbaalenii_PYR-1 ---GRASLIELNGDLAA-AHSVAVLVPGVNTTMEG--------------- MAB_0252|M.abscessus_ATCC_1997 ---GNGRMIEMIGDIKPGVRGVGVIVPGTNTNLNG--------------- MSMEG_0365|M.smegmatis_MC2_155 ---GNGRMIEMIGEIKPGIKGVGVVVPGTNTNLNG--------------- Mb2105|M.bovis_AF2122/97 -FGGKGRAAIAIGNPDT-AKHTAVIVPGTSSSVKGG---------WLHDN Rv2079|M.tuberculosis_H37Rv -FGGKGRAAIAIGNPDT-AKHTAVIVPGTSSSVKGG---------WLHDN MMAR_5468|M.marinum_M -FNGEGKAAIAIGNPDY-ARNTAVVVPGTGSSVAQG---------WMSD- MAV_1467|M.avium_104 IIDDKGHAAVSLNNPDT-AKRNATFVPGTGQDLTRF---------DASAD TH_2466|M.thermoresistible__bu ---EHPKVAVALGDVET-ADHVSVYVPGTGSVTYDKPDAGNDLPTYVEQS MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK --SAANAATARRFVSGSDGRLAMITYLGGPFPQVHDPVTAVA-AADRRYA Mvan_3447|M.vanbaalenii_PYR-1 --SAANTATARRFVSATDGDVAVITYLGGPFPQVHNPADVLFDAADARYA MAB_0252|M.abscessus_ATCC_1997 --SGSNHESAVKLAKESGS--PIFLYLGGDFPQGLD------KAADPSYA MSMEG_0365|M.smegmatis_MC2_155 --SGSNHTSAVELSKQSGS--PVFLYMDGDFPQGLD------KAADPAYA Mb2105|M.bovis_AF2122/97 HDDALNLFNQAKAADPNNP-TAVIAWMGYDAPNDFTDPRIATPMLARIGG Rv2079|M.tuberculosis_H37Rv HDDALNLFNQAKAADPNNP-TAVIAWMGYDAPNDFTDPRIATPMLARIGG MMAR_5468|M.marinum_M HDDATNLYDQALAADPEHHYTAVIAWMGYDAPNGFSDVRVTEPGLARSGG MAV_1467|M.avium_104 KSRAMLQATMNADKSLQPGDVSVTTWMGYDRP--MNVFEAASTSYAHNGA TH_2466|M.thermoresistible__bu GWLKAETERVLEQAGRSDETVATVAWLGYEPPANVA------QAGSPHYA MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK LEMAPRLVAFSEDVARRVPD---SVLVTVVGHSYGGSIVGTAETLG-LTS Mvan_3447|M.vanbaalenii_PYR-1 LDMAPRLVAFSEDVDRRVSD---GVAVTVIGHSYGGSIVGTAETLG-LTS MAB_0252|M.abscessus_ATCC_1997 AAMAPKLVDFGHEVDRAVGQNAPGTPVTYVGHSYGGAIVGTAEQMG-LRA MSMEG_0365|M.smegmatis_MC2_155 ASMAPKLVSFGHEIDREVGIGAPDTPVTYIGHSYGGAIVGTAEQMG-LRA Mb2105|M.bovis_AF2122/97 AALAEDVNGLWVTHLGVG------QNVTVLGHSYGSTTVADAFALGGMHA Rv2079|M.tuberculosis_H37Rv AALAEDVNGLWVTHLGVG------QNVTVLGHSYGSTTVADAFALGGMHA MMAR_5468|M.marinum_M ALLANDVNGLWVTHNSLTP-----QHVTVIGHSYGSTTVADAFAGSGMHA MAV_1467|M.avium_104 AALDDFQAGVRASHNDAVTGGR-PSLNTVIGHSYGSTEVGAAALNGHHLD TH_2466|M.thermoresistible__bu DDNAPKLASFINGLNSSRDT---DPNLTVLGHSYGSLVASEALQRG-TAA MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK DRTVFLAAAGAGVGVDDPGDWHNRNPHVQRYSMTAPGDFIELVQGIP--- Mvan_3447|M.vanbaalenii_PYR-1 DRTVFLGAAGAGVGVDDTGDWHNRNPHVLRYSMTAPGDFIELVQGIP--- MAB_0252|M.abscessus_ATCC_1997 DRILHASSAGTGILP---GGYTDPNPNVQRYSMTAPGDPIAIVQSLPRDV MSMEG_0365|M.smegmatis_MC2_155 DRVLHASSAGTGILS---GDYTNPNPNVQRFSMTAPGDPISLVQSLPRDV Mb2105|M.bovis_AF2122/97 NDAVLLGCPGTDLAHS--AASFHLD-GGRVYVGAASTDPISMLGQLDSLS Rv2079|M.tuberculosis_H37Rv NDAVLLGCPGTDLAHS--AASFHLD-GGRVYVGAASTDPISMLGQLDSLS MMAR_5468|M.marinum_M NDAILIGCPGTDLARS--AADFHLD-GGQVYVGSASTDPVSWIGESSGVP MAV_1467|M.avium_104 ADNVIAVASPGMLTGH--ASDLNLDPGSHVFATRAQNDIIGVVTG----- TH_2466|M.thermoresistible__bu DNVVFMGSPGLETNVW----EWHKNVTPEKLHLSEGHVFVQHADN----- MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK ---------------------------GGPHGADPDEMDGVIGLPTGFYD Mvan_3447|M.vanbaalenii_PYR-1 ---------------------------GGPHGVDPDEMNGVIPLRTGEYD MAB_0252|M.abscessus_ATCC_1997 RLSDVPGVDQIPGIPHNVEGRIGNPLGGLPSATDPDKIPGVTRLDTGYYG MSMEG_0365|M.smegmatis_MC2_155 AISSIPGVDSIPGIPHNTDGRIGNPLGGLPSATDPDNIPGVTRLDTGYYG Mb2105|M.bovis_AF2122/97 QYVNRGNL------------------AGQLQGLAVGLGTDPAGDGFGSVR Rv2079|M.tuberculosis_H37Rv QYVNRGNL------------------AGQLQGLAVGLGTDPAGDGFGSVR MMAR_5468|M.marinum_M GELLKGKLRE----------------YGVPIPLDAGLGRDPAGDGFGSVR MAV_1467|M.avium_104 ----------------------------------MTLGPDPTGASFGGTP TH_2466|M.thermoresistible__bu -----------------------------DIVANLGRYGAVIPSELPGFI MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK DGG-----LVAGWEAHSGMLNRP-SGAWRTILDVLTGDPGTLSSASSIPA Mvan_3447|M.vanbaalenii_PYR-1 DGG-----PVAGWDAHSGMLNRP-SDSWRTILAIITGDCPTVRRAVAGAP MAB_0252|M.abscessus_ATCC_1997 EFGKHPNQVIVGPDGHGSYWDDPSSDAFHNIAAVIGGGEATGYVERGIQT MSMEG_0365|M.smegmatis_MC2_155 AEGAHPNQVIVGPDGHGKYWDDYDSDAFKNMVAVISGGEATGYVERGIET Mb2105|M.bovis_AF2122/97 FRAEVPNSDGINPHDHSYYYHRG-SEALRSMADIASGHGDALASDGMLAQ Rv2079|M.tuberculosis_H37Rv FRAEVPNSDGINPHDHSYYYHRG-SEALRSMADIASGHGDALASDGMLAQ MMAR_5468|M.marinum_M FHAEVPGSATMDRHDHSHYYVMG-SESLRSITDIASGHPDRLASDDLIAE MAV_1467|M.avium_104 FEAAPGKAWPFG---------------LPSIGAHGS-YWDNMSNPALINM TH_2466|M.thermoresistible__bu DLSTNAESTPLGPRDASSGHSEYSFINKTALYNQAVVVAGLGQDDRFIRV MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK GG------------------------------------------------ Mvan_3447|M.vanbaalenii_PYR-1 T------------------------------------------------- MAB_0252|M.abscessus_ATCC_1997 NYVDINVGDDGNFRAEAWDQSRAAAGAQVPGLPWDDPGTIDRRHHPWDNP MSMEG_0365|M.smegmatis_MC2_155 NYVDIDLGDDGDFRDEAADQAKAGAAPKAPRLPWDDNGTYERRQHPWDNP Mb2105|M.bovis_AF2122/97 PRHQPGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLH Rv2079|M.tuberculosis_H37Rv PRHQPGVEIDIPGLGSVEIDIPGTPASIDPEWSRPPGSITDDHVFDAPLH MMAR_5468|M.marinum_M GRRQP-------HVG--PFRVPGVPAYIDPESDRPRDTVHDDHHYPAYQP MAV_1467|M.avium_104 GRIIAG-------------RTDVTPPTFTP-------------------- TH_2466|M.thermoresistible__bu ED------------------------------------------------ MUL_1136|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3088|M.gilvum_PYR-GCK --------------- Mvan_3447|M.vanbaalenii_PYR-1 --------------- MAB_0252|M.abscessus_ATCC_1997 RVTDHPEHGQKIQVK MSMEG_0365|M.smegmatis_MC2_155 RVTDNPGLGPRVPVR Mb2105|M.bovis_AF2122/97 R-------------- Rv2079|M.tuberculosis_H37Rv R-------------- MMAR_5468|M.marinum_M PR------------- MAV_1467|M.avium_104 --------------- TH_2466|M.thermoresistible__bu --------------- MUL_1136|M.ulcerans_Agy99 ---------------