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MTHMRRVVACAATVAALMIGVTGCSNWRGLNSVSLPGTEGGGPGAFDIQVQMPDITNLQPNSRVRVADVT VGTVTKVERQGWHALLTLRLNGDVNLPANCTATIGQTSLLGSLHVELAPPAAAPPQGRLHQGSLIPLADS TTHPTTEQTLAAVSMLLNGGGLGQMQDITKALSTALRGREADLRNLIGQLETFVAKTNDQTGDIIEATEK LNRLTGKFAAQQPVVDKAVRTIPDALEVLKDQRDNLTAALDQLGRFSALAADSTRQTKDSLVREFRNIGP VLESLANAGPNMTRALSILTTYPFPNETLEKWLRGDYGNMTAIVDLTLSRIDAGFFTGTRWEGDLTELEM QWGRTIGQLPSPYTAVNPLVAPYRWDQGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0350 | - | - | 100% (379) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_4786 | - | 5e-74 | 40.52% (343) | virulence factor mce family protein |
| M. smegmatis MC2 155 | MSMEG_2859 | - | 6e-74 | 41.62% (334) | virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 2e-66 | 40.18% (341) | MCE-family lipoprotein LprK |
| M. gilvum PYR-GCK | Mflv_2105 | - | 1e-142 | 66.40% (378) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1970 | lprM | 1e-139 | 65.22% (368) | MCE-family lipoprotein LprM |
| M. leprae Br4923 | MLBr_02593 | lprK | 1e-63 | 37.78% (360) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 2e-59 | 36.09% (338) | MCE-family protein LprN |
| M. marinum M | MMAR_4055 | lprM_1 | 1e-156 | 69.54% (371) | MCE family lipoprotein LprM |
| M. avium 104 | MAV_2536 | - | 1e-140 | 63.35% (382) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4336 | - | 1e-146 | 66.84% (374) | PUTATIVE MCE-family lipoprotein LprM_1 |
| M. ulcerans Agy99 | MUL_3922 | lprM_1 | 1e-156 | 69.54% (371) | MCE family lipoprotein LprM |
| M. vanbaalenii PYR-1 | Mvan_3978 | - | 1e-159 | 70.29% (377) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0350|M.smegmatis_MC2_155 ----MT-HMRRVVA----CAATVAALMIGVTGCSNWRGLNSVSLPGTEGG
Mvan_3978|M.vanbaalenii_PYR-1 ----MSRTWRRRIM----LSAATIAVVMGMSGCADWQGLNSLPMPGTEGG
Rv1970|M.tuberculosis_H37Rv ----------MRIG----LTLVMIAAVVASCG---WRGLNSLPLPGTQGN
TH_4336|M.thermoresistible__bu --------MRSATV----SALALVVLSAALLAGCGWQGLNSVPLPGTQGR
MMAR_4055|M.marinum_M ---MMWARWTTRIR----IAAGIAALAVAVSGCSGWRGLNSLPLPGVQGG
MUL_3922|M.ulcerans_Agy99 ----MRAGWTTRIR----IAAGIAALAVAVSGCSGWRGLNSLPLPGVQGG
Mflv_2105|M.gilvum_PYR-GCK ----MTAVRASATM----ALAVTMAAAVTVSGC-GWRGLNSVPLPGTQGG
MAV_2536|M.avium_104 ----MSQSPLRRRV----MAALLAAVALATLSGCGFRGLNSFNLPGTKGG
MAB_4149c|M.abscessus_ATCC_199 --------MSRNVL----RAAVMGVGVAVVVSGCQFNGLNSLNLPGTAGH
Mb0179|M.bovis_AF2122/97 ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGGPGT
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVR-HQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGS
. :.*:... :** *
MSMEG_0350|M.smegmatis_MC2_155 GPGAFDIQVQMPDITNLQPNSRVRVADVTVGTVTKVERQ-----GWHALL
Mvan_3978|M.vanbaalenii_PYR-1 GPGSFVIQAQLPDVNNIQPNSRVRVGDVNVGTVTKVERQ-----GWHALL
Rv1970|M.tuberculosis_H37Rv GPGSFAVQAQLPDVNNIQPNSRVRVADVTVGHVTKIERQ-----GWHALV
TH_4336|M.thermoresistible__bu GADAFTIQAQLPDVNNLQQNSRVRVGDVDVGTVAKIERQ-----GWHALV
MMAR_4055|M.marinum_M GPGSFTIQAQMPDVDNIEPNSRVRVGDVNVGTVTKIERQ-----GWHALV
MUL_3922|M.ulcerans_Agy99 GPGSFTIQAQMPDVDNIEPNSRVRVGDVNVGTVTKIERQ-----GWHALV
Mflv_2105|M.gilvum_PYR-GCK GPGSFTIQAQMPDVDNVEQNSRVRVGDVNVGTVSKIERQ-----GWNALV
MAV_2536|M.avium_104 GPGAYTIRAQMPDVQNLQRNSRVRVNDVTVGNVIDIELQ-----GWNALV
MAB_4149c|M.abscessus_ATCC_199 GSRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGV
Mb0179|M.bovis_AF2122/97 GPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLK-----NWVATL
MLBr_02593|M.leprae_Br4923 GKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLK-----NWVATL
* :: : .::** : ** * * ** ** : :. .* * :
MSMEG_0350|M.smegmatis_MC2_155 TLRLNGDVNLPANCTATIGQTSLLGSLHVELAPPAAAPPQGRLHQGSLIP
Mvan_3978|M.vanbaalenii_PYR-1 TMRLNADVNLPENSTVTIGLTSILGSLHIELSPPAGAAPVGRLHDGSLIP
Rv1970|M.tuberculosis_H37Rv TMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGEARQGKLRDGSLIA
TH_4336|M.thermoresistible__bu TIRLNGDVDLPANSTVTVGQTSLLGSLHVELAPPVDEPPQGSLRDGAFIP
MMAR_4055|M.marinum_M TMKLNGNVELPANATATLGQTSLLGSLHIELAPPTDVPPEGNLREGSLIP
MUL_3922|M.ulcerans_Agy99 TMKLNGNVELPANATATLGQTSLLGSLHIELAPPTDVPPEGNLREGSLIP
Mflv_2105|M.gilvum_PYR-GCK TMTLNGDVNLPANATAKVGQTSLLGSQHIELAAPADEAPQGRLEEGTLIP
MAV_2536|M.avium_104 TMTIDGDVDLPANATATLGQTSLLGSVHVELAPPAGVAPQGKLKNGSLIP
MAB_4149c|M.abscessus_ATCC_199 KVSLEPEVHLPANAVAKVAQTSLLGSQHIELAAPVGEPAVGKLTGGATIP
Mb0179|M.bovis_AF2122/97 TLSLKKDVTLPKNATAKIGQTSLLGSQHVELAAPPD-PSPVPLKDGDTIP
MLBr_02593|M.leprae_Br4923 TLGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAPAN-PSLELLKNGDTIP
.: :. :* ** * ...:. **:*** *:**:.* . * * *.
MSMEG_0350|M.smegmatis_MC2_155 LADSTTHPTTEQTLAAVSMLLNGGGLGQMQDITKALSTALRGREADLRNL
Mvan_3978|M.vanbaalenii_PYR-1 LSSGGAFPSTEQTLAALSMVLNGGGLGQVQDITEAFSTAFDGREHDVRSL
Rv1970|M.tuberculosis_H37Rv LSHGSAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFAGREHDLRGL
TH_4336|M.thermoresistible__bu LDSGGAYPSTEQTLAAVSLLLNGGGLGQVQDITRALSTAFGGREDELRSL
MMAR_4055|M.marinum_M LSSSKAYPSTEQALAATAMLLNGGGIGDIYDITEALSTAFTGRENDLRSL
MUL_3922|M.ulcerans_Agy99 LSSSKAYPSTEQALAATAMLLNGGGIGDIYDITEALSTAFTGRENDLRSL
Mflv_2105|M.gilvum_PYR-GCK LASAGAYPSTEQALAAVALLLNGGGLGNIQDITDALSTAFSGRENDLRSL
MAV_2536|M.avium_104 LSSAGAYPSTERTLAAVSLLLNGGGLGQVQDITKTLSTAFSGREQDLRNL
MAB_4149c|M.abscessus_ATCC_199 LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV
Mb0179|M.bovis_AF2122/97 LKRSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAF
MLBr_02593|M.leprae_Br4923 LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF
* .*:**..*:: : ::. *.: : : . ** :: .
MSMEG_0350|M.smegmatis_MC2_155 IGQLETFVAKTNDQTGDIIEATEKLNRLTGKFAAQQPVVDKAVRTIPDAL
Mvan_3978|M.vanbaalenii_PYR-1 IGQLETFARNVNDQTGDIIAATESLNNLVGQFAAQRPVLDHALQTIPDAL
Rv1970|M.tuberculosis_H37Rv IGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIPDAL
TH_4336|M.thermoresistible__bu MSRLETFTSRINDQTDDVIAATEALNRLVAQFSSQRPVVDKALDTIPAAL
MMAR_4055|M.marinum_M IEQLDEAIGHLDDQKGDIIAAAESLNNLMAQLAAQRPVLDKALRTIPDAL
MUL_3922|M.ulcerans_Agy99 IEQLDEAIGHLDDQKGDIIAAAESLNNLMAQLAAQRPVLDKALRTIPDAL
Mflv_2105|M.gilvum_PYR-GCK IEQLDIAVGHLDDQTGDIIATSESLNNVVGQIAEQKPVVDKALRTIPDAL
MAV_2536|M.avium_104 LNQLDTFVGYLNDQKSDIIAATDHLNNLVGQFADQKPIIDKALKTIPQAL
MAB_4149c|M.abscessus_ATCC_199 LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL
Mb0179|M.bovis_AF2122/97 LGKLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLPPLI
MLBr_02593|M.leprae_Br4923 LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI
: :* :.* .*: : : :.. .. : ..: : : :
MSMEG_0350|M.smegmatis_MC2_155 EVLKDQRDNLTAALDQLGRFSALAADSTRQTKDSLVREFRNIGPVLESLA
Mvan_3978|M.vanbaalenii_PYR-1 AVLDGERQNLIETADQFGKFSALTVDTVNKTKDNLVKELNDVGPVLESLA
Rv1970|M.tuberculosis_H37Rv AVLADERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLESLA
TH_4336|M.thermoresistible__bu AVLNSEREELIEAVEELGTFNELAADTIDQTRDAVVEELRDMGPVLESLA
MMAR_4055|M.marinum_M AVLKNERENLADALTQLGRFSALAADSVNQTKDALVQELKDLGPTLESLA
MUL_3922|M.ulcerans_Agy99 TVLKNERENLADALTQLGRFSALAADSVNQTKDALVQELKDLGPTLESLA
Mflv_2105|M.gilvum_PYR-GCK AVLRDQRDTLSEALVQLGRFSALAADSVTKTREALIQELKDLGPVLQSLA
MAV_2536|M.avium_104 TVLKDERENLANALGEVGQLSALAADSVNKTKENLIKELKDLGPVLQSLA
MAB_4149c|M.abscessus_ATCC_199 KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA
Mb0179|M.bovis_AF2122/97 KHFADKQELLINASDAVGRLSQSADQYLSAARGDLHQDLQALQCPLKELR
MLBr_02593|M.leprae_Br4923 KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG
: : : : .. : . : : ::. : :. *
MSMEG_0350|M.smegmatis_MC2_155 NAGPNMTRALSILTTYPFPNETLEKWLRGDYGNMTAIVDLTLSRIDAGFF
Mvan_3978|M.vanbaalenii_PYR-1 DAGPSMTRALSLIPTFPFPNETIEKWQRGDYANLTAIADLTLSRIDAGMF
Rv1970|M.tuberculosis_H37Rv NSGPALTRSLSLLATFPFPNETFQNFQRGEYANLTAIVDLTLSRIDQGLL
TH_4336|M.thermoresistible__bu NAGPALTRSLSLFTTFPFPKETLTKWMRGDYANITVVADLTLSRMDSALF
MMAR_4055|M.marinum_M NAGPALTRALSFLPTYPFPKETLTNWMRGDYANLTLIIDMTLSRIDAGFF
MUL_3922|M.ulcerans_Agy99 NAGPALTRALSFLPTYPFPKETLTNWMRGDYANLTLIIDMTLSRIDAGFF
Mflv_2105|M.gilvum_PYR-GCK DAGPALTRALSFLPTFPFPKETLTNWMRGDYANLTLVVDLTLSRIDQGFF
MAV_2536|M.avium_104 DAGPALTRSLGFLGTFPFPAETLSKWIRGDYANLTAVIDLTLSRLDASFL
MAB_4149c|M.abscessus_ATCC_199 ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF
Mb0179|M.bovis_AF2122/97 RAAPYLVGALKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYSAIDNAFL
MLBr_02593|M.leprae_Br4923 RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL
: :: :: * *: . . : **:* *: *:* :. .:
MSMEG_0350|M.smegmatis_MC2_155 TGTRWEGDLTELEMQWGR-TIGQLP-SPYTA------VNPLVAPYRWDQG
Mvan_3978|M.vanbaalenii_PYR-1 TGTRWEGDLTELELQWGR-TIGQFP-SPYTR------ANPLTVPYRWDQG
Rv1970|M.tuberculosis_H37Rv TGTRWECHLTQLELQWGR-TIGQFP-SPCTAGYRGTPGNPLTIAYRWDQG
TH_4336|M.thermoresistible__bu TGTRWEGDLTELEMQWGR-TIGQLP-SPYTA------ANPLLAPYRWNQG
MMAR_4055|M.marinum_M TGTRWEGDLTELELQWGR-TIGQMP-SPY------TVGNPLIVPYRWDQG
MUL_3922|M.ulcerans_Agy99 TGTRWEGDLTELELQWGR-TIGQMP-SPY------TVGNPLIVPYRWDQG
Mflv_2105|M.gilvum_PYR-GCK TGTRFECNLTWLELQWGR-TIGQTP-SPCNHNVPPPGSNPLVAPYRWDQG
MAV_2536|M.avium_104 TGTRFECNLTELELQWGR-TIGQLP-SPCTGGGPYNPGNPLVVPYHFDQG
MAB_4149c|M.abscessus_ATCC_199 TTSFFDPNMQHFNDVVNP-PEWLIG-SMANLNGKETSPFDLPAPAAPQGG
Mb0179|M.bovis_AF2122/97 TGTGFSGALRALEQSFGRDPETMIPDIRYTPNPNDAPGGPLVERGNRQC-
MLBr_02593|M.leprae_Br4923 TGTGLSGALRALEQSFGRDPETMIPDVRYTTNPNDAPGGPLVERADRRC-
* : . : :: . . *
MSMEG_0350|M.smegmatis_MC2_155 R-
Mvan_3978|M.vanbaalenii_PYR-1 P-
Rv1970|M.tuberculosis_H37Rv P-
TH_4336|M.thermoresistible__bu P-
MMAR_4055|M.marinum_M P-
MUL_3922|M.ulcerans_Agy99 P-
Mflv_2105|M.gilvum_PYR-GCK R-
MAV_2536|M.avium_104 R-
MAB_4149c|M.abscessus_ATCC_199 GR
Mb0179|M.bovis_AF2122/97 --
MLBr_02593|M.leprae_Br4923 --