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SKQERRTQLLEVARELIREAGTEDFTLGRLADRAGVTKPVVYDHFGDKSGALAELYREFEARRRETLAAA LEEAADDLDAVAHAVAEAYIDCCAAEGRELSGVVAALEGSPTLSLLRQEADDAYLDVCGRALFPSSVPAR SAGLRAIIGAGDALFRDVLADRITPTDACETLARVVAAVAASATPGSRPESPAPDRRSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0285 | - | - | 100% (200) | transcriptional regulator TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5424 | - | 2e-09 | 48.15% (54) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 1e-08 | 28.65% (185) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 5e-09 | 48.15% (54) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1947 | - | 4e-09 | 48.15% (54) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 6e-09 | 48.15% (54) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-09 | 26.00% (150) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 1e-10 | 53.70% (54) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4466 | - | 6e-09 | 48.15% (54) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4155 | - | 2e-09 | 36.84% (95) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0912 | - | 1e-09 | 50.00% (54) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4635 | - | 4e-09 | 48.15% (54) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4778 | - | 8e-09 | 48.15% (54) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4466|M.marinum_M ----------------------MPEKEAKAPRARMTGSERRHQLIGIARS
MUL_4635|M.ulcerans_Agy99 ----------------------------------MTGSERRHQLIGIARS
Mb1047|M.bovis_AF2122/97 ----------------------------------MTGTERRHQLIGIARS
Rv1019|M.tuberculosis_H37Rv ----------------------------------MTGTERRHQLIGIARS
Mflv_1947|M.gilvum_PYR-GCK ----------------------------------MTGSERRQQLIEIAKS
Mvan_4778|M.vanbaalenii_PYR-1 --------------MAVSDKRGGPDTHVRAPRARMTGTERRQQLVEIAKS
TH_0912|M.thermoresistible__bu ----------------------------------MTGSERRQQLIEIAKS
MAB_1149|M.abscessus_ATCC_1997 -----------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARS
MAV_4155|M.avium_104 MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASD
MSMEG_0285|M.smegmatis_MC2_155 ----------------------------------MSKQERRTQLLEVARE
MLBr_01070|M.leprae_Br4923 -----------MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAER
:. :*. :: :*
MMAR_4466|M.marinum_M LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGK----EGLYAVVVDREMS
MUL_4635|M.ulcerans_Agy99 LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGK----EGLYAVVVDREMS
Mb1047|M.bovis_AF2122/97 LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGK----EGLYAVVVDREMS
Rv1019|M.tuberculosis_H37Rv LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGK----EGLYAVVVDREMS
Mflv_1947|M.gilvum_PYR-GCK LFAERGFDGTSIEEIALRANVSKPVVYEHFGGK----EGLYAVVVDREMS
Mvan_4778|M.vanbaalenii_PYR-1 LFAERGFDGTSIEEIALRANVSKPVVYEHFGGK----EGLYAVVVDREMS
TH_0912|M.thermoresistible__bu LFAERGYEGTSIEEIALRANVSKPVVYEHFGGK----EGLYAVVVDREMS
MAB_1149|M.abscessus_ATCC_1997 LFAERGYEATSIEEIAQRAGVSKPVVYEHFGGK----EGLYAVVVDREMS
MAV_4155|M.avium_104 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSK----LELYLAVLARHVE
MSMEG_0285|M.smegmatis_MC2_155 LIREAGTEDFTLGRLADRAGVTKPVVYDHFGDKSGALAELYREFEARRRE
MLBr_01070|M.leprae_Br4923 LLAERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRS
:: : : .:* *.:::*..* :* .* * . : .
MMAR_4466|M.marinum_M ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
MUL_4635|M.ulcerans_Agy99 ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
Mb1047|M.bovis_AF2122/97 ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
Rv1019|M.tuberculosis_H37Rv ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
Mflv_1947|M.gilvum_PYR-GCK ALLDGITSSLADNR-SRVRVERVALALLTYVEERTDGFRILIRDSPASIT
Mvan_4778|M.vanbaalenii_PYR-1 ALLDGITSSLADNR-SRVRVERVALALLTYVEEHTDGFRILIRDSPASIT
TH_0912|M.thermoresistible__bu ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRILIRDSPAAIT
MAB_1149|M.abscessus_ATCC_1997 VLLDGITSSLTSYR-SRVRLEQVALALLSYIEERTDGFRILIRDSPPGVS
MAV_4155|M.avium_104 NLVSGVQQALSTTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFEN-DYVTE
MSMEG_0285|M.smegmatis_MC2_155 TLAAALEEAADDLD---AVAHAVAEAYIDCCAAEGRELSGVVAALEGSPT
MLBr_01070|M.leprae_Br4923 AVEALAEQLPADPA---AVWRSAITAFFEVCGTHRAVAVAGAAAKATSPE
: . . . * :
MMAR_4466|M.marinum_M SGTYSSLLNDAVSQVSSILAGDFARRGLDSELAPLYAQALVGSVSMTAQW
MUL_4635|M.ulcerans_Agy99 SGTYSSLLNDAVSQVSSILAGDFARRGLDSELAPLYAQALVGSVSMTAQW
Mb1047|M.bovis_AF2122/97 SGTYSSLLNDAVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVSMTAQW
Rv1019|M.tuberculosis_H37Rv SGTYSSLLNDAVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVSMTAQW
Mflv_1947|M.gilvum_PYR-GCK QGTYSTLLNDAVSQVESILAGDFSRRGLDPDLAPLYAQALVGSVSMAAQW
Mvan_4778|M.vanbaalenii_PYR-1 SGTYSTLLNDAVSQVASILAGDFSRRGLDPDLAPLYAQALVGSVSMAAQW
TH_0912|M.thermoresistible__bu SGTYSTLLNDAVNQVSSILAGDFSRRGLDPEMAPLYAQALVGSVSMTAQW
MAB_1149|M.abscessus_ATCC_1997 SGTYSSLLNDAVSQVSSILAGDFQRRGLDAEMAPLYAQALVGQVSMTAQW
MAV_4155|M.avium_104 PEVAAQVRVATESCIDAVYALISEDSGLDPHRARMIAVGLVGISVDCARY
MSMEG_0285|M.smegmatis_MC2_155 LSLLRQEADDAYLDVCGRALFPSSVPARSAGLRAIIGAGDALFRDVLADR
MLBr_01070|M.leprae_Br4923 VRRLWSTVMQQWIDYNTAAIQAERKCGVAP--DTIPAEDLAVALQLMTER
. . : . . :
MMAR_4466|M.marinum_M WLDAREPKKEVVAAH-LVNLVWNGLTHLEADPQLQDE
MUL_4635|M.ulcerans_Agy99 WLDAREPKKEVVAAH-LVNLVWNGLTHLEADPQLQDE
Mb1047|M.bovis_AF2122/97 WLDAREPKKEVVAAH-LVNLVWNGLTHLEADPRLQDE
Rv1019|M.tuberculosis_H37Rv WLDAREPKKEVVAAH-LVNLVWNGLTHLEADPRLQDE
Mflv_1947|M.gilvum_PYR-GCK WLDVREPKKEVVAAH-LVNLCWNGLTHLESDPVLHEE
Mvan_4778|M.vanbaalenii_PYR-1 WLDVREPKKEVVAAH-LVNLCWNGLTHLESDPVLHEE
TH_0912|M.thermoresistible__bu WLDVREPKKEVVAAH-LVNLCWNGLTHLEPDPVLHEE
MAB_1149|M.abscessus_ATCC_1997 WLDAREPKKEVVAAH-IVNLCWHGLKHLEADPQLHEE
MAV_4155|M.avium_104 WLDSDRPISKADAVEGTVAFAWGGLSHVPLTRS----
MSMEG_0285|M.smegmatis_MC2_155 ITPTDACETLARVVAAVAASATPGSRPESPAPDRRSR
MLBr_01070|M.leprae_Br4923 VMAATFSDEKPLIPD---KKVIDTLVHIWLASIYGS-