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RYLTLAVSLGTATALAVLTACSSAETTESESTTTTTPKVQPTPVIGSVLAEPIPVPTTDGRTHLAYELML TNPMSGNVTLNAVSVMDGDRKLLTLSGDSLKYWTRALGNPAAPANVLGPGQSATVWLDVVADDPAQVPTE LTHAIDLTVAKPMPPLIPANVTETIAPVSVQTRKPPSISPPLTGDRWLDINSCCDMTAHRMALNPINGKI WAAERFAIDYVQLGTDGRIYTGNKAAVESYPYFGAEIRAVADGPVVSVLDGQPEQTPGVTPSGLTLEQYG GNHIVQDIGDGVYAFYAHLQPGSLKVKPGDQLSTGQAIASLGNSGNSDAPHLHFHVMDGPDPLAADGLPF VFDSFRLDSRLTSATAGDALLDGKPAALQPGFATREVSEVSPLVLDVMTYASD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0247 | - | - | 100% (404) | secreted peptidase |
| M. smegmatis MC2 155 | MSMEG_1192 | - | 7e-63 | 40.06% (352) | M23 peptidase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1864 | - | 3e-07 | 35.24% (105) | peptidase M23B |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00154 | - | 5e-05 | 30.10% (103) | hypothetical protein MLBr_00154 |
| M. abscessus ATCC 19977 | MAB_1055c | - | 3e-06 | 41.18% (68) | hypothetical protein MAB_1055c |
| M. marinum M | MMAR_3448 | - | 2e-61 | 35.73% (389) | hypothetical protein MMAR_3448 |
| M. avium 104 | MAV_1073 | - | 1e-06 | 42.00% (50) | M23 peptidase domain-containing protein |
| M. thermoresistible (build 8) | TH_1774 | - | 8e-07 | 36.17% (94) | peptidoglycan-binding LysM |
| M. ulcerans Agy99 | MUL_2722 | - | 6e-58 | 37.87% (338) | hypothetical protein MUL_2722 |
| M. vanbaalenii PYR-1 | Mvan_3705 | - | 2e-08 | 28.72% (195) | peptidase M23B |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1864|M.gilvum_PYR-GCK --MPQHRLPR----SRAALTTPG------LSEVTDIIPFDEFGALGDI--
TH_1774|M.thermoresistible__bu --LAKHRAVSPAGDSTDAHRHPRQGFDPHPAEITEIIPLSGFGRLSDLG-
MLBr_00154|M.leprae_Br4923 MAAEAVRSFR----NRWLNHQRN--------DVTEIIPVDGFDDFDDLYD
MAV_1073|M.avium_104 --MRVGRAPG----ARSAEPHRT--------EVTEILPLDGFD-FDDLDF
MAB_1055c|M.abscessus_ATCC_199 ------------------------------------MPIDEFGLSDALER
Mvan_3705|M.vanbaalenii_PYR-1 --MVHHRIAR-----PDAAADRG------ATDVTEIIAFGEFGALMDMA-
MMAR_3448|M.marinum_M MAYEQPRHRA----RSPFWKSLAVFWLALSVAACSSSTTSAEGASTNANG
MUL_2722|M.ulcerans_Agy99 MLIEYHWRRR----RFDQRQ------RHRQRARGSNGSRRVHTADHRAN-
MSMEG_0247|M.smegmatis_MC2_155 --MRYLTLAV----SLGTATALAVLTACSSAETTESESTTTTTPKVQPT-
.
Mflv_1864|M.gilvum_PYR-GCK ------------DDLEFLQDA-------AFGRDAEVIDAPELDDCHDTDD
TH_1774|M.thermoresistible__bu ------------ADTDFYGDAWDDEWDVAFDRESEVVSAPELDD-LDPDA
MLBr_00154|M.leprae_Br4923 LDFA------EIDELQFSDDDYN------FCNETQVLLASEIDDLQDIDS
MAV_1073|M.avium_104 CDDAG-----DHGDLDFSTDSP-------FDNEAQVLLAPELDDLNETDD
MAB_1055c|M.abscessus_ATCC_199 P---------ELEDYDVYEDAPEEG---AEIEDQTALDQLEQDWEEDTDE
Mvan_3705|M.vanbaalenii_PYR-1 ---------------SCRSDP--------FAIDFEVLSAPELDDLNDLAD
MMAR_3448|M.marinum_M TNNALEGVTVPDAFTPLTIAPISRPTFPFPGTDGKYHLAYDVQITNATGA
MUL_2722|M.ulcerans_Agy99 --------------QPADVS--------VPGTDDKYHLAYDVQITNATGA
MSMEG_0247|M.smegmatis_MC2_155 ----------------PVIGSVLAEPIPVPTTDGRTHLAYELMLTNPMSG
: :
Mflv_1864|M.gilvum_PYR-GCK LTP-LRLAVPAEFRAEPAAARRASTRAYRDSHTDVSDGSAKTDVIDMRAH
TH_1774|M.thermoresistible__bu EAP-LRLVVPSEFRPDPRDER-PSGHAYRDSHTDVSDGTAATDVIAIG-R
MLBr_00154|M.leprae_Br4923 LAS-EPLAASAN------VAPNFTSAP---RRP-----------------
MAV_1073|M.avium_104 LRP-LWLAAPVTE-----VLPRTTVAARTERRPERPRG---ADVVGVARR
MAB_1055c|M.abscessus_ATCC_199 ADR-IRASIEAT-------ADWFAASAARTRDPRDTP----TDKLPRISS
Mvan_3705|M.vanbaalenii_PYR-1 ESPRLLLAPTGSTNTAPPTVPIHVGGAHLRECPRPSRR--ALSGSNVRAS
MMAR_3448|M.marinum_M PAALTSVDVVDAQDPSKVLTSFSGTQLVDPKCSYGNCN-------RLRQL
MUL_2722|M.ulcerans_Agy99 PAALTSVDVVDSQDPSKVLTSFSGTQLVDPKCSYGNCN-------RLRQL
MSMEG_0247|M.smegmatis_MC2_155 NVTLNAVSVMDGD---RKLLTLSGDSLKYWTRALGNPA-------APANV
.
Mflv_1864|M.gilvum_PYR-GCK KGQHRKT-EVP--VKGRLVVAAMAVGATAAGAYTMTKN--VPAAPAETVL
TH_1774|M.thermoresistible__bu RGQHRKP-EPTSAGKGRLMIAAMAAGATAAGAYSVVNGDDEKSSTDATVL
MLBr_00154|M.leprae_Br4923 -CQHRK--QPTSATRGRLLISAMAAGAMATAAHTVISH--DDIPKTETVL
MAV_1073|M.avium_104 GGQHRK--QPTSAARGRLLISAMAAGAAAAAAHTATSH--ADTPKTDAVL
MAB_1055c|M.abscessus_ATCC_199 GGVHRRR-EIGQVGKTRLALAAMAAGAAAAAGYNALSE-----HDAATAA
Mvan_3705|M.vanbaalenii_PYR-1 GGAHRKTPEAAGAAHSRLVITAIAVGAIAAAANAADDA----TEAQQPVL
MMAR_3448|M.marinum_M TGRPSTDFTIPPQGSRALLLDFTFDKLAQFPKAVMLRLHGTGVTAPGSSA
MUL_2722|M.ulcerans_Agy99 TGRPSTDFTIPPQGSRALLLDFTFDKLAQFPKAVMLRLHGTGVTAPGSSA
MSMEG_0247|M.smegmatis_MC2_155 LG---------PGQSATVWLDVVADDPAQVPTELTHAIDLT-VAKPMPPL
: : .
Mflv_1864|M.gilvum_PYR-GCK ASDSTTLGDGTVITGSVDGMQIVSVAPASNSTVHAEEITKAAAFAQERAE
TH_1774|M.thermoresistible__bu AADQAAMPD--AIDGATGGMQIVTVAQPAKAIVHAEEITKAAAFAQERAE
MLBr_00154|M.leprae_Br4923 TANASALSG-ATVSDATQGVQVITVHPAASTAVHNEEHAKGTAFAHERAQ
MAV_1073|M.avium_104 TANASSLTGGAGGSNTVRGPQVIAAEPAATAALHNQELAKGVAFANDRAQ
MAB_1055c|M.abscessus_ATCC_199 DHHGLALGN-SAAVMATHGPQLVSAPLATDASVTDEQLAKATAFATERAD
Mvan_3705|M.vanbaalenii_PYR-1 VADTAASPA---ALPGPSGMQIVPVANSFDAGIHRQELANGTAYAQERAQ
MMAR_3448|M.marinum_M ESGPLDTLG-APFDISAGTPRVISPPLRGNNWVAFNGCCEPGWAHRDSIL
MUL_2722|M.ulcerans_Agy99 ESGPLDTLG-APFDISAGTPRVIGPPLRGNNWVAFNGCCEPGWAHRDSIL
MSMEG_0247|M.smegmatis_MC2_155 IPANVTETI-APVSVQTRKPPSISPPLTGDRWLDINSCCD-MTAHRMALN
: : : .
Mflv_1864|M.gilvum_PYR-GCK REARLTKPQFVMPTTGVWTSGFGYRWGVLHAGIDIANAIGTPVLAAADGI
TH_1774|M.thermoresistible__bu REARLARPQFVMPTTGVWTSGFGYRWGVLHGGIDIANSVGTPILAAADGV
MLBr_00154|M.leprae_Br4923 REARLSQPLYVMPTKGIFTSNFGYRWGVLHAGIDLANAIGTPILAVSDGV
MAV_1073|M.avium_104 REARLQQPLYVMPTKGIFTSNFGYRWGVLHAGIDLANSIGTPIYAVSDGV
MAB_1055c|M.abscessus_ATCC_199 REKRLLAPRFVMPTNGTFTSGFGYRWGALHGGIDIANSIGTPIVAAADGV
Mvan_3705|M.vanbaalenii_PYR-1 REARLRRPQFAFPSRGILTSGFGARWGTLHAGLDIANAVGTPIYAASDGE
MMAR_3448|M.marinum_M PLNMKLNNSQRFAIDWMRTNDQGNFFAGDKTNNDSYISYGSSVYAVADGT
MUL_2722|M.ulcerans_Agy99 PLNMKLNNSQRFAIDWMRTNDQGNFFAGDKTNNDSYISYGSSVYAVADGT
MSMEG_0247|M.smegmatis_MC2_155 PINGKIWAAERFAIDYVQLGTDGRIYTGNKAAVESYPYFGAEIRAVADGP
:. . * : : : *: : *.:**
Mflv_1864|M.gilvum_PYR-GCK VIASGAEGG-----------------------YGNAVKLRHADGTVTLYG
TH_1774|M.thermoresistible__bu VIETGPQGG-----------------------YGIWVKLRHYDGTVTVYA
MLBr_00154|M.leprae_Br4923 VIDVGPTAG-----------------------YGMWVKLRHADGTVTLYG
MAV_1073|M.avium_104 VIEAGPAGG-----------------------YGMLVKLRHADGTVTLYG
MAB_1055c|M.abscessus_ATCC_199 VIATGPTAG-----------------------YGAWVKIRHSDGTVTLYG
Mvan_3705|M.vanbaalenii_PYR-1 VIASGPTPG-----------------------FGMWVKIRAADGTVTLYG
MMAR_3448|M.marinum_M VTSTLDDMEANVPGILPASDPALAAKITVDNVDGNHIVLDIGGGAYAMYA
MUL_2722|M.ulcerans_Agy99 VTSTLDDMEANVPGILPASDPALAAKITVDNVDGNHIVLDIGGGAYAMYA
MSMEG_0247|M.smegmatis_MC2_155 VVSVLDGQPEQTPGVTPSG-------LTLEQYGGNHIVQDIGDGVYAFYA
* * : .*. :.*.
Mflv_1864|M.gilvum_PYR-GCK HNS--SLLVSVGERVMAGDQIAKMGNTGNSTGPHLHFEVHLNGT------
TH_1774|M.thermoresistible__bu HLS--SVLVNVGQRVMAGDQIARMGNTGNSTGPHLHFEVLLDGV------
MLBr_00154|M.leprae_Br4923 HVN--TTLVNVGQYVVAGDQIATMGTRGNSTGPHLHFEVLLSGS------
MAV_1073|M.avium_104 HIN--TALVSVGERVMAGDQIATMGNRGNSTGPHLHFEVLQGGT------
MAB_1055c|M.abscessus_ATCC_199 HIN--TWEVSVGQRVMAGDRIATIGNRGNSTGPHLHFEVLLGGS------
Mvan_3705|M.vanbaalenii_PYR-1 HID--TTNVQTGQRVMAGDQIATMGNRGNSTGPHLHFEVHLNGT------
MMAR_3448|M.marinum_M HLIKGSLLVKPGDKVKKGQEIAKLGNTGNSNAPHLHFQLMDGPSLLEADA
MUL_2722|M.ulcerans_Agy99 HLIKGSLLVKPGDKVKKGQEIAKLGNTGNSNAPHLHFQLMDGPSLLEADA
MSMEG_0247|M.smegmatis_MC2_155 HLQPGSLKVKPGDQLSTGQAIASLGNSGNSDAPHLHFHVMDGPDPLAADG
* : *. *: : *: ** :*. *** .*****.: .
Mflv_1864|M.gilvum_PYR-GCK -----DRVDPTGWLAKRGLSP-GGYVG-----------------------
TH_1774|M.thermoresistible__bu -----NRVDPAAWLAKRGVGPNSGYMR-----------------------
MLBr_00154|M.leprae_Br4923 -----ERIDPVPWLAKRGIYV-GNYTG-----------------------
MAV_1073|M.avium_104 -----ERIDPVPWLAKRGLMV-GNYAG-----------------------
MAB_1055c|M.abscessus_ATCC_199 -----QRIDPQGWLANKGLTF-TRFGD-----------------------
Mvan_3705|M.vanbaalenii_PYR-1 -----DKIDPMAWLGERGIPN-----D-----------------------
MMAR_3448|M.marinum_M LPYVLDTFSYQGQVSPATVWDADNYLSGSFFGPDRLAAPEPRTKQLPVLL
MUL_2722|M.ulcerans_Agy99 LPYVLDTFSYQGQISPATVWDADNYLSGSFFGPDRLAAPEPRTKQLPVLL
MSMEG_0247|M.smegmatis_MC2_155 LPFVFDSFRLDSRLTSATAGDALLDGKPAALQPG--FATREVSEVSPLVL
: . :
Mflv_1864|M.gilvum_PYR-GCK --------
TH_1774|M.thermoresistible__bu --------
MLBr_00154|M.leprae_Br4923 --------
MAV_1073|M.avium_104 --------
MAB_1055c|M.abscessus_ATCC_199 --------
Mvan_3705|M.vanbaalenii_PYR-1 --------
MMAR_3448|M.marinum_M AIVNFG--
MUL_2722|M.ulcerans_Agy99 AIVNFG--
MSMEG_0247|M.smegmatis_MC2_155 DVMTYASD