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PQPAPPALTVRCDGSERTFAAGHDVVVGRDLRADMRITHPLISRAHLLLRFDQGRWLAIDNNSLNGTFVN GRRVPMVEIYDGQSLNIGNPDGPLLSFEVGRHVGMAGRPPQTESMRVTPSMVRPSGQHPVAHGPTSTGSH TSHEAPPTARFHPGAAPPGPARTGQPMYPSSSAPWRPTGYPASPAPPPPSNFPPPPPRPGPQPPQQATKP PEVANLATKMFHALLPRSGGAERPAGSVTIGRATDNDIVIPDVLASRHHAFLTLTPLGTEIRDAHSVNGT FVNGVRVGSAVLSDGDVVTIGNVDLVFTGGTLIRRTEAATRSGGLEVKSVCFTVDGGKQLLDHISLTARP GTLTAIIGGSGAGKTTLSRLIAGYTSPSSGTVTFEGHNIHAEYASMRSRIGMVPQDDVVHRQLTVSQALG YAAELRLPPDTSKEDRAQVVAQVLEELELTKHAETRVDKLSGGQRKRASVALELLTGPSLLILDEPTTGL DPALDRQVMLMLRQLADAGRVVLIVTHSVAYLDVCDQLLLVAPGGKTAFLGPPSEISQAMGTANWADIFT NVGADPDEANRRFLEQKQEQPAFPSEASPAVDLGEPVHTDVLHQFSTVARRQIRLVISDRGYTVFLALLP FLIGTLTLTVRGKTGYGMSDPMGNNPAQPDQILVMLNVGAVFMGTALTIRDLIGERPIFRREQAVGLSTA AYMGAKIVVFCAFAVTQAAIATTISVVGWGKPLSDAVLLGDVRFELFVTVAATCVASALLGMALSSLAQS QDQIMPMLVVSIMSQLVFSGGMIWVTNRFLLDQLSWLTPARWGFAASASTIDTHRLVPGPTDPKDQHWDH KASAWLFDMAMLAVLSIAYTAIVWWKIRLKRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1174 | - | - | 100% (873) | transmembrane ATP-binding protein ABC transporter |
M. marinum M | MMAR_2612 | - | 0.0 | 65.83% (878) | transmembrane ATP-binding protein ABC transporter |
M. marinum M | MMAR_1173 | - | 0.0 | 64.60% (873) | transmembrane ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1776 | - | 0.0 | 66.06% (878) | transmembrane ATP-binding protein ABC transporter |
M. gilvum PYR-GCK | Mflv_4882 | - | 0.0 | 63.82% (890) | ABC transporter related |
M. tuberculosis H37Rv | Rv1747 | - | 0.0 | 66.06% (878) | transmembrane ATP-binding protein ABC transporter |
M. leprae Br4923 | MLBr_02352 | - | 1e-20 | 29.20% (226) | putative antibiotic resistance efflux protein |
M. abscessus ATCC 19977 | MAB_3698 | - | 0.0 | 56.60% (871) | ABC transporter ATP-binding protein |
M. avium 104 | MAV_4325 | - | 0.0 | 72.38% (858) | ABC transporter, ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_1642 | - | 0.0 | 63.89% (900) | ABC transporter, ATP-binding protein |
M. thermoresistible (build 8) | TH_4260 | - | 0.0 | 69.10% (670) | PUTATIVE ABC transporter, ATP-binding protein |
M. ulcerans Agy99 | MUL_3149 | - | 0.0 | 65.83% (878) | transmembrane ATP-binding protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_1546 | - | 0.0 | 63.83% (882) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1174|M.marinum_M --------MPQPAPPALTVRCDGSERTFAAGHDVVVGRDLRADMRITHPL MAV_4325|M.avium_104 ---------------------------------MVVGRDLRADMRITHPL MSMEG_1642|M.smegmatis_MC2_155 -------MSRPSPP-ALTVRYEGSTRTFAPGSDVVIGRDLRADVRIAHPL TH_4260|M.thermoresistible__bu -------------------------------------------------- Mflv_4882|M.gilvum_PYR-GCK -------MSRPGSP-ALTVRYDGSTHTFAAGNDVVVGRDLRADVRIAHPL Mvan_1546|M.vanbaalenii_PYR-1 -------MSRPATP-ALTVRYDGSTRSFAAGNDVVVGRDLRADIRIAHPL Mb1776|M.bovis_AF2122/97 -----MPMSQPAAPPVLTVRYEGSERTFAAGHDVVVGRDLRADVRVAHPL Rv1747|M.tuberculosis_H37Rv -----MPMSQPAAPPVLTVRYEGSERTFAAGHDVVVGRDLRADVRVAHPL MUL_3149|M.ulcerans_Agy99 MPLQLVPMTQTAAPPVLTVRYNGAERTFAAGHDVVIGRDLRADVRVADPL MAB_3698|M.abscessus_ATCC_1997 -------MTGREAP-TLTVVFDGDERKFAPGHDIHIGRDIHADVRITHPL MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M ISRAHLLLRFDQGRWLAIDNNSLNGTFVNGRRVPMVEIYDGQSLNIGNPD MAV_4325|M.avium_104 ISRAHLLLRYDQGKWLAIDNGSLNGTFVNGRRVPVVEIHDGCAINIGNPD MSMEG_1642|M.smegmatis_MC2_155 ISRAHLVLRFDQGRWVAIDNGSLNGMYVNGRRVSSVDLQDGQVLNIGNPD TH_4260|M.thermoresistible__bu -------------------------------------------------- Mflv_4882|M.gilvum_PYR-GCK ISRAHLVLRFDQGRWIAIDNGSLNGMYVNGRRVPAADISDGGQLHIGNPD Mvan_1546|M.vanbaalenii_PYR-1 ISRAHLVLRFDQGRWLAIDNGSLNGMYVNGRRVPAAEITDGTQVHIGNPD Mb1776|M.bovis_AF2122/97 ISRAHLLLRFDQGRWVAIDNGSLNGLYLNNRRVPVVDIYDAQRVHIGNPD Rv1747|M.tuberculosis_H37Rv ISRAHLLLRFDQGRWVAIDNGSLNGLYLNNRRVPVVDIYDAQRVHIGNPD MUL_3149|M.ulcerans_Agy99 ISRVHLLLRFDQGRWIAIDNGSLNGLYINNRRVPVVDIQDGQRVNIGNPD MAB_3698|M.abscessus_ATCC_1997 VSRIHLIIRFVDGKWIAEDQRSLNGIFVNGRQVGWVEVRDDTVINLGDPG MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M GPLLSFEVG-RHVGMAGRPPQTESMRVTPSMVRPS------GQHPVAHGP MAV_4325|M.avium_104 GPLLTFDVG-RHQGMAGRPPRTESMGIPVAAHPPAPAAWSAQPAPPVAAP MSMEG_1642|M.smegmatis_MC2_155 GPQLSFEVG-RHQGSAGRTP-TAAVPVAG-HTGTS----WPTQAPTGGGW TH_4260|M.thermoresistible__bu -------------------------------------------------- Mflv_4882|M.gilvum_PYR-GCK GPLLTFEVG-RHQGSAGTPPSTTAVPVPG-RTSAT----WPAQHS-GPTG Mvan_1546|M.vanbaalenii_PYR-1 GPLLVFEVG-RHQGSAGSPPPTAAVPVAG-RPSAT----WPSQP------ Mb1776|M.bovis_AF2122/97 GPALDFEVG-RHRGSAGRPPQTTSIRLPN-LSAGA----WPTDGP--PQT Rv1747|M.tuberculosis_H37Rv GPALDFEVG-RHRGSAGRPPQTTSIRLPN-LSAGA----WPTDGP--PQT MUL_3149|M.ulcerans_Agy99 GPALDFGVGRRQQGSVGRPPPTAVMQVPPPMPSGP----WPSQAP--PQT MAB_3698|M.abscessus_ATCC_1997 GPRLTFALG----GLGGETQLGIAPPTMRGYVSGA------QQQAPYTGA MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M TSTGSHTSHEAPPTARFHPGAAPPGPARTGQPMYPSSSAPWRPTGYPASP MAV_4325|M.avium_104 PPPAGRTPNWAAPPRRPQP-APRPGPP--GQTMYGGR----PPGGYPPAA MSMEG_1642|M.smegmatis_MC2_155 QQPYTQPPRTQYPQTTGTQQRYPSAPQHGYPNGPQTGYPSGPQRGYPSGP TH_4260|M.thermoresistible__bu -------------------------------------------------- Mflv_4882|M.gilvum_PYR-GCK RPPVQRPPTGPYPGAGAYPPGGPRPVPAPPPPAAQ-SRPAHVQQPISAPA Mvan_1546|M.vanbaalenii_PYR-1 -PPSQPPPTGRPPAQRPYP-SAPRPSAPPTYPTPQPSRPAPVQPPLSSPA Mb1776|M.bovis_AF2122/97 GTLGSGQLQQLPPATTRIPAAPPSGP--------QPRYPTGGQQLWPPSG Rv1747|M.tuberculosis_H37Rv GTLGSGQLQQLPPATTRIPAAPPSGP--------QPRYPTGGQQLWPPSG MUL_3149|M.ulcerans_Agy99 GSHRPVPPQPAPP-TTRMPAQPPSGPQHVQPSDQQPQYPSGPQTSRSQTG MAB_3698|M.abscessus_ATCC_1997 QQHGTTGQPYHSTQQHYPTGGYQSGPQTYGQPPSQQHPYGAAPSGPQTYG MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M APPPPSNFPPPPPRPGPQPPQQATKPPE---------------------- MAV_4325|M.avium_104 PPPPP--VAPAPAAPHTQMAPAASKPPE---------------------- MSMEG_1642|M.smegmatis_MC2_155 QTGYPTNG--PAGAPQSYQSQPVRTPPPAPANSSQAPTTMGPAAAPRGGA TH_4260|M.thermoresistible__bu ----------------------VRSPE----------------------- Mflv_4882|M.gilvum_PYR-GCK MDPVTVMG--PAAAP--------RSSGS---------------------- Mvan_1546|M.vanbaalenii_PYR-1 MESATVMG--PAAAP--------RSGG----------------------- Mb1776|M.bovis_AF2122/97 PQRAPQIYRPPTAAPPPAG----ARGGT---------------------- Rv1747|M.tuberculosis_H37Rv PQRAPQIYRPPTAAPPPAG----ARGGT---------------------- MUL_3149|M.ulcerans_Agy99 AQPAPQIYRPPAASPAPPAPLVVGRAPG---------------------- MAB_3698|M.abscessus_ATCC_1997 TSGPTRPRQQYPSEPTPVP---ASYSNE---------------------- MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M --VANLATKMFHALLP-RSGGAERPAGSVTIGRATDNDIVIPDVLASRHH MAV_4325|M.avium_104 --VANLATKMFQALMPSRSGAIQKPAGSQTIGRATDNDIVIQDVLASRHH MSMEG_1642|M.smegmatis_MC2_155 EPASNLATSMLKILRPGRSA--PAPAGAVKIGRATDNDIVIPDVLASRHH TH_4260|M.thermoresistible__bu --INNLATSMMKILRPGRAQ--EAPPGSIKIGRAVDNDIVIPDVLASRHH Mflv_4882|M.gilvum_PYR-GCK --DGNIATSMLRILRPGRPA--DVPAGSIKIGRSSDNDIVIPDVLASRHH Mvan_1546|M.vanbaalenii_PYR-1 --DGNIATSMLKILRPGRPA--EAPPGSIKIGRSTDNDIVIPDVLASRHH Mb1776|M.bovis_AF2122/97 -EAGNLATSMMKILRPGRLTG-ELPPGAVRIGRANDNDIVIPEVLASRHH Rv1747|M.tuberculosis_H37Rv -EAGNLATSMMKILRPGRLTG-ELPPGAVRIGRANDNDIVIPEVLASRHH MUL_3149|M.ulcerans_Agy99 -ETGNIATSMMKILRPGRAAG-ELPPGAVTIGRADDNDIVIPEVLASRHH MAB_3698|M.abscessus_ATCC_1997 -PVEPFGTRAMRALGIGGAP--KPTPGAITVGRAPDNTIVVNDVLASRHH MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M AFLTLTPLGTEIRDAHSVNGTFVNGVRVGSAVLSDGDVVTIGNVDLVFTG MAV_4325|M.avium_104 AFLIQTPLGTEIRDAHSVNGTFVNGVRVGSAVLTEGDVVTIGNVDLVFTR MSMEG_1642|M.smegmatis_MC2_155 ATLIPLPGGTEIRDERSINGTFVNGTRVDSAVLHDGDVVTIGNVDLVFSG TH_4260|M.thermoresistible__bu ATLVPTPAGMEIRDNRSINGTFVNGTRTETAVLNEGDVVTIGNVDLVFRN Mflv_4882|M.gilvum_PYR-GCK ATLVPTPAGTEIRDNRSINGTFVNGSRVDSAILADGDTVTIGNVDLSFRD Mvan_1546|M.vanbaalenii_PYR-1 ATLVHSPAGTEIRDNRSINGTFVNGARVDSAMLTEGDTVTIGNVDLVFRD Mb1776|M.bovis_AF2122/97 ATLVPTPGGTEIRDNRSINGTFVNGARVDAALLHDGDVVTIGNIDLVFAD Rv1747|M.tuberculosis_H37Rv ATLVPTPGGTEIRDNRSINGTFVNGARVDAALLHDGDVVTIGNIDLVFAD MUL_3149|M.ulcerans_Agy99 ATLIPTPQGTEIRDNRSINGTFVNGARVEAALLHDGDVVTIGNIDLIFAN MAB_3698|M.abscessus_ATCC_1997 ALLLPTPGGLEIQDLHTINGTFVNGVQVEQSSLREGDTVTIGNVDLVVQD MLBr_02352|M.leprae_Br4923 -----------MRNN-------------DKAVMVRGVRKTYG-------- ::: : : * * * MMAR_1174|M.marinum_M GTLIRR--TEAATRSGGLEVKSVCFTVDGGKQLLDHISLTARPGTLTAII MAV_4325|M.avium_104 DGLIRR--TEAATRSGGLEVNSVCYTVDHGKQLLDHISLTARPGTLTAII MSMEG_1642|M.smegmatis_MC2_155 GTLARRSETEADTRTGGLEVRGLTWTIEGNKTLLDNISIDARPGTLTAVI TH_4260|M.thermoresistible__bu GTLVRRTETEAATDAGGLDVRGVTWTIENNKTLLDNISITARPGTLTAII Mflv_4882|M.gilvum_PYR-GCK GTLVRRTETAAATATGGLDVHGVTWTIENNKTLLDNISMSARPGTLTAVI Mvan_1546|M.vanbaalenii_PYR-1 GTLVRRTETAAATATGGLDVHGVTWTIENNKTLLDNISMSARPGTLTAVI Mb1776|M.bovis_AF2122/97 GTLARREENLLETRVGGLDVRGVTWTIDGDKTLLDGISLTARPGMLTAVI Rv1747|M.tuberculosis_H37Rv GTLARREENLLETRVGGLDVRGVTWTIDGDKTLLDGISLTARPGMLTAVI MUL_3149|M.ulcerans_Agy99 GALARREESLLETRTGGLDVHGVTWTIEGNKTLLDNISLAARPGMLTAVI MAB_3698|M.abscessus_ATCC_1997 GTLVKP---TTATRVGGLEVQSIDFVVEGGKKLLDDISFSAGPGSLTAVI MLBr_02352|M.leprae_Br4923 ---------------------------KGKIIALDDVSFDVDRGEVIGLL . ** :*: . * : .:: MMAR_1174|M.marinum_M GGSGAGKTTLSRLIAGYTSPSSGTVTFEGHNIHAEYASMRSRIGMVPQDD MAV_4325|M.avium_104 GGSGAGKTTLSRLIVGYTTPTSGTVTFEGHNIHTEYASMRSRIGMVPQDD MSMEG_1642|M.smegmatis_MC2_155 GPSGAGKSTFARQVAGYTHPTSGTIKFEGHDVHAEYASLRSRIGMVPQDD TH_4260|M.thermoresistible__bu GPSGAGKSTFARLIAGYTHPTSGTVTFEGHNVHAEYASLRSRIGMVPQDD Mflv_4882|M.gilvum_PYR-GCK GPSGAGKSTFARLVAGYTHPTTGQVSFEGHDVHAEYASLRSRIGMVPQDD Mvan_1546|M.vanbaalenii_PYR-1 GPSGAGKSTFARLVAGYTHPTTGQVSFEGHDVHAEYASLRSRIGMVPQDD Mb1776|M.bovis_AF2122/97 GPSGAGKSTLARLVAGYTHPTDGTVTFEGHNVHAEYASLRSRIGMVPQDD Rv1747|M.tuberculosis_H37Rv GPSGAGKSTLARLVAGYTHPTDGTVTFEGHNVHAEYASLRSRIGMVPQDD MUL_3149|M.ulcerans_Agy99 GPSGAGKSTFARLVAGYTHPTNGTVTFEGHNIHAEYASLRSRIGMVPQDD MAB_3698|M.abscessus_ATCC_1997 GPSGAGKSTLARLIVGNTQPSAGKVSFEGHGVHAEYAVMRNRIGMVPQDD MLBr_02352|M.leprae_Br4923 GPNGAGKTTMVDILSTLTRPDRGLATVAGYDVVSEPAGVRRSIMVTGQQV * .****:*: : * * * .. *:.: :* * :* * :. *: MMAR_1174|M.marinum_M VVHRQLTVSQALGYAAELRLPPDTSKEDRAQVVAQVLEELELTKHAETRV MAV_4325|M.avium_104 VVHRQLTVNQALGYAAELRLPPDTSKEERARVVAQVLEELDMTQHAETRV MSMEG_1642|M.smegmatis_MC2_155 VVHGQLTVRQALMYAAELRLPPDTTKEDREQVVMQVLEELEMTKHLDTRV TH_4260|M.thermoresistible__bu VVHGQLTVNQALMYAAELRLPPDTTEEDRRQVVAEVLEELEMTAHADTRV Mflv_4882|M.gilvum_PYR-GCK VVHGQLTVRQALMYAAELRLPPDTTKADREQVVNEVLEELEMTKHLDTRV Mvan_1546|M.vanbaalenii_PYR-1 VVHGQLTVRQALMYAAELRLPPDTTKADREQVVNEVLEELEMTKHLDTRV Mb1776|M.bovis_AF2122/97 VVHGQLTVKHALMYAAELRLPPDTTKDDRTQVVARVLEELEMSKHIDTRV Rv1747|M.tuberculosis_H37Rv VVHGQLTVKHALMYAAELRLPPDTTKDDRTQVVARVLEELEMSKHIDTRV MUL_3149|M.ulcerans_Agy99 VVHGQLTVRQALMYAAELRLPPDTTKEDREHVVARVLEELEMSKHLETRV MAB_3698|M.abscessus_ATCC_1997 VVHPQLTVSQALHYAAELRLPPDTTKEDREQVVSRVLEELEMTKHAETRV MLBr_02352|M.leprae_Br4923 AVDDQLSGEQNLILFGRLYGLSKSVARVR---TQELLEQFDLLHAGKRRV .*. **: : * ..* ..: * . .:**:::: . ** MMAR_1174|M.marinum_M DKLSGGQRKRASVALELLTGPSLLILDEPTTGLDPALDRQVMLMLRQLAD MAV_4325|M.avium_104 DKLSGGQRKRASVALELLTQPSLLLLDEPTSGLDPALDRQVMLMLRQLAD MSMEG_1642|M.smegmatis_MC2_155 DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD TH_4260|M.thermoresistible__bu DKLSGGQRKRASVAMELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD Mflv_4882|M.gilvum_PYR-GCK DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD Mvan_1546|M.vanbaalenii_PYR-1 DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD Mb1776|M.bovis_AF2122/97 DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD Rv1747|M.tuberculosis_H37Rv DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD MUL_3149|M.ulcerans_Agy99 DKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDRQVMTMLRQLAD MAB_3698|M.abscessus_ATCC_1997 DKLSGGQRKRASVAMELLTGPSLLILDEPTSGLDPALDRQVMSLMRQLAD MLBr_02352|M.leprae_Br4923 GTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKQ .. *** *:* .:* *:. *.: :*****:**** : : :: .: : MMAR_1174|M.marinum_M AGRVVLIVTHSVAYLDVCDQLLLVAPGGKTAFLGPPSEISQAMGTANWAD MAV_4325|M.avium_104 AGRVVLVVTHSVSYLDVCDQILLIAPGGKTAFCGPPDQVEPALGTRNWAD MSMEG_1642|M.smegmatis_MC2_155 AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFFGPPSQIGPELGTTNWAD TH_4260|M.thermoresistible__bu AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFYGPPSQIGPTMGTTNWAD Mflv_4882|M.gilvum_PYR-GCK AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFYGPPSQIGSAMGTTNWAD Mvan_1546|M.vanbaalenii_PYR-1 AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFYGPPSQIGPSMGTTNWAD Mb1776|M.bovis_AF2122/97 AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFCGPPTQIGPVMGTTNWAD Rv1747|M.tuberculosis_H37Rv AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFCGPPTQIGPVMGTTNWAD MUL_3149|M.ulcerans_Agy99 AGRVVLVVTHSLTYLDVCDQVLLLAPGGKTAFCGPPSQIGPAMGTTNWAD MAB_3698|M.abscessus_ATCC_1997 AGRVVVVVTHSLTYLSYCDQVLLLAPGGKTAYCGPPRSIGQEMGTTDWAD MLBr_02352|M.leprae_Br4923 IGIATLLTTQYLEEADELSDRIILIDHGTVIAEGTASELKHRVG-----E * ..::.*: : . .: ::: *.. *.. .: :* : MMAR_1174|M.marinum_M IFTNVGADPDEANRRFLEQKQEQPAFPSEASPAVDLG-EPVHTDVLHQFS MAV_4325|M.avium_104 IFAKVGADPDEANRRFKERNQQSSQPPTPQSP-ADLG-EPPQTDLWRQLS MSMEG_1642|M.smegmatis_MC2_155 IFSTVADDPAEANRRYLARTPEAPPASASSEAPADLG-APAKTSLRRQFS TH_4260|M.thermoresistible__bu IFSTVAGDPDAANRRFLERQGPPRELPAESAKPTDLG-SPTRTSLRRQFS Mflv_4882|M.gilvum_PYR-GCK IFSSVAGDPEAAAARYLSQNGPPPPQPP-ALTPSELG-NPTRTSLRRQLS Mvan_1546|M.vanbaalenii_PYR-1 IFSAVAGDPDAAAQRYLAQNGPPPPQPP-ALTPSELG-NPTRTSLRRQLS Mb1776|M.bovis_AF2122/97 IFSTVADDPDAAKARYLARTGPTPPPPP-VEQPAELG-DPAHTSLFRQFS Rv1747|M.tuberculosis_H37Rv IFSTVADDPDAAKARYLARTGPTPPPPP-VEQPAELG-DPAHTSLFRQFS MUL_3149|M.ulcerans_Agy99 IFSTVADDPEGAQARYLAQTGPPPPAPP-VERPGELGGDPSHTSLFRQFS MAB_3698|M.abscessus_ATCC_1997 IFANAAADPDGVHQAYLSRHPAANKPATAASPPGDLG-KPPKTSLLRQVS MLBr_02352|M.leprae_Br4923 TFCEIVP-----------------------RDLKDLG------TVVAALG * :** : .. MMAR_1174|M.marinum_M TVARRQIRLVISDRGYTVFLALLPFLIGTLTLTVRG-KTGYGMSD---PM MAV_4325|M.avium_104 TIARRQVRLVVSDRGYTIFLAVLPFLIGALSLTVKGPHPGLGPAD---PL MSMEG_1642|M.smegmatis_MC2_155 TIGRRQLRLIISDRGYFIFLALLPFIMGTLSLSVPG-TVGFGVPN---PM TH_4260|M.thermoresistible__bu TIARRQIRLIVSDRGYFVFLALLPFIMGVLSLSVPG-DVGFGVPN---PM Mflv_4882|M.gilvum_PYR-GCK TIARRQIRLVISDRGYFAFLMLLPFIMGILSLSVPG-DVGFGVPKTALEG Mvan_1546|M.vanbaalenii_PYR-1 TIARRQIRLVISDRGYFAFLMLLPFIMGVLSLSVPG-DVGFGVPKTALEG Mb1776|M.bovis_AF2122/97 TIARRQLRLIVSDRGYFVFLALLPFIMGALSMSVPG-DVGFGFPN---PM Rv1747|M.tuberculosis_H37Rv TIARRQLRLIVSDRGYFVFLALLPFIMGALSMSVPG-DVGFGFPN---PM MUL_3149|M.ulcerans_Agy99 TIARRQMRLIISDRGYFIFLAILPFVMGSLSMSVPG-DVGFGMPN---PM MAB_3698|M.abscessus_ATCC_1997 TVARRQGRLILADRGYFIFLALLPFVLAGLVLSVPG-SAGFNVALP---- MLBr_02352|M.leprae_Br4923 SLLPERSRAMLT-------------------------------------- :: .: * ::: MMAR_1174|M.marinum_M GNNPAQPDQILVMLNVGAVFMGTALTIRDLIGERPIFRREQAVGLSTAAY MAV_4325|M.avium_104 GPAPTQPQYIMVLLNIGAVFMGTALTIRDLIGERAIFRREQAVGLSTTAY MSMEG_1642|M.smegmatis_MC2_155 GDAPNEPGQILVLLNVGAIFMGTALTIRDLIGERAIFRREQAVGLSTTAY TH_4260|M.thermoresistible__bu GDAPNEPGQILVLLNVGAIFMGTALTIRDLIGERAIFRREQAVGLSTTAY Mflv_4882|M.gilvum_PYR-GCK GEAPNEPGQILVMLNVGAIFMGTALTIRALIGERAIFRREQAVGLSTSAY Mvan_1546|M.vanbaalenii_PYR-1 GEAPNEPGQILVMLNVGAIFMGTALTIRALISERAIFRREQAVGLSTSAY Mb1776|M.bovis_AF2122/97 GDAPNEPGQILVLLNVGAVFMGTALTIRDLIGERAIFRREQAVGLSTTAY Rv1747|M.tuberculosis_H37Rv GDAPNEPGQILVLLNVGAVFMGTALTIRDLIGERAIFRREQAVGLSTTAY MUL_3149|M.ulcerans_Agy99 GNAPNEPGQILVLLNVGAVFMGTALTIRDLIGERAIFRREQAVGLSTTAY MAB_3698|M.abscessus_ATCC_1997 -DNPNEPGLLLALTNLGASFLGLALTIRDLIGERVIFRREQAVGLSATAY MLBr_02352|M.leprae_Br4923 ---PTSDRITMPAPDGTQTLIEAARRIDEVS------------------- * . : : :: * * : MMAR_1174|M.marinum_M MGAKIVVFCAFAVTQAAIATTISVVGWGKP-----LSDAVLLGDVRFELF MAV_4325|M.avium_104 LLAKIAVFCVFATAQAAIATIIVRLGKGAP-----TAHPQFFGNSTFSLF MSMEG_1642|M.smegmatis_MC2_155 LLAKVCVYSVFAVVQSAIVTVITISGKGWG--EGAVERGVVIPNRSLELF TH_4260|M.thermoresistible__bu LLAKVCVYSVFAIVQSAIVTAITIAGKGWDVDKGAVDHGSVFGNPKLELF Mflv_4882|M.gilvum_PYR-GCK LLAKVVVFTAFAIVQAAIVTTIAIIGKGWG--PGAVDSGAVVGDRSIELF Mvan_1546|M.vanbaalenii_PYR-1 LLAKVVVFTAFAIVQAAIVTSIAIAGKGWG--PGAVERGAVIGNRSVELF Mb1776|M.bovis_AF2122/97 LIAKVCVYTVLAVVQSAIVTVIVLVGKGGP-----TQGAVALSKPDLELF Rv1747|M.tuberculosis_H37Rv LIAKVCVYTVLAVVQSAIVTVIVLVGKGGP-----TQGAVALSKPDLELF MUL_3149|M.ulcerans_Agy99 LLAKICVYTVFAVVQSAIVTIIVLIGKGGP-----TQGAVALGKPGLELF MAB_3698|M.abscessus_ATCC_1997 LLAKIITYCGAAIVQSAIMTAVIVIVRGGP-----TQGAVLLGSANFELW MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M VTVAATCVASALLGMALSSLAQSQDQIMPMLVVSIMSQLVFSGGMIWVTN MAV_4325|M.avium_104 VTVAGTCIASAMLGLLLSALAQSNEQIMPLLVVSIMSQLVFSSGMIPVYQ MSMEG_1642|M.smegmatis_MC2_155 LSMAATTVTAAMVGLALSALAKTSEQIMPLLVVAIMSQLVFSGGMIPVTG TH_4260|M.thermoresistible__bu FGMAATTVAAAMLGLLLSALAKTSEQIMPLLVVAIMSQLVFSGGMIPVTD Mflv_4882|M.gilvum_PYR-GCK LDIAVTCVASAMVGLALSALAKSAEQIMPLLVVAIMSQLVFSGGMIPVTD Mvan_1546|M.vanbaalenii_PYR-1 TDIAVTCVAAAMVGLALSALAKSAEQIMPLLVVAIMSQLVFSGGMIPVTD Mb1776|M.bovis_AF2122/97 VDVAVTCVASAMLGLALSAIAKSNEQIMPLLVVAVMSQLVFSGGMIPVTG Rv1747|M.tuberculosis_H37Rv VDVAVTCVASAMLGLALSAIAKSNEQIMPLLVVAVMSQLVFSGGMIPVTG MUL_3149|M.ulcerans_Agy99 ADVAATCVASAMLGLALSAVAKSNEQIMPLLVVAVMSQLVFSGGMIPVTD MAB_3698|M.abscessus_ATCC_1997 VAVAATACAATVLGLVLSSLATSAEQVMPMLVIATMTQIVFSGGLIPVTG MLBr_02352|M.leprae_Br4923 VELADIALRRPSLDDVFLSMTTDPSESLSHLAAGAMR------------- :* . :. : ::: .: :. *. . * MMAR_1174|M.marinum_M RFLLDQLSWLTPARWGFAASASTIDTHRLVPGPTDPK-DQHWDHKASAWL MAV_4325|M.avium_104 RIGLEQLAWLTPARWGYAAGASSIDFPSLVKVKQIPTNDPIWQHSKHIFV MSMEG_1642|M.smegmatis_MC2_155 RIGLDQLSWITPARWGFAASASTVDLIRLVPGPLTPK-DSHWEHTSGTWL TH_4260|M.thermoresistible__bu RIGLDQLSWFTPARWGFAASASTADLITLVPGPLTPK-DRHWEHDSGTWL Mflv_4882|M.gilvum_PYR-GCK RLVLDQMSWFTPARWGFAASASTVDLIRLVPGPLTPQ-DRHWEHTPGTWL Mvan_1546|M.vanbaalenii_PYR-1 RIVLDQMSWFTPARWGFAASASTVDLIRLVPGPLTPQ-DRHWQHTTGAWL Mb1776|M.bovis_AF2122/97 RVPLDQMSWVTPARWGFAASAATVDLIKLVPGPLTPK-DSHWHHTASAWW Rv1747|M.tuberculosis_H37Rv RVPLDQMSWVTPARWGFAASAATVDLIKLVPGPLTPK-DSHWHHTASAWW MUL_3149|M.ulcerans_Agy99 RLGLDQMSWATPARWGFATSASTVDLIKLVPGPLTPK-DSHWHHTASAWW MAB_3698|M.abscessus_ATCC_1997 RAGLEQLSFLFPSRWGFAATAATCDLRKLVP--VGPQ-DELWNHDAGTWL MLBr_02352|M.leprae_Br4923 -------------------------------------------------- MMAR_1174|M.marinum_M FDMAMLAVLSIAYTAIVWWKIRLKRR- MAV_4325|M.avium_104 FDMAMLALLSIGYTGFVRWHIRLKR-- MSMEG_1642|M.smegmatis_MC2_155 FDMAMLGVLSVFYVTFVRWKIRLKAG- TH_4260|M.thermoresistible__bu FDMAMLAVLSVFYLALVRWKIRLPRA- Mflv_4882|M.gilvum_PYR-GCK FDMGMLALISVGYLALVRWRIRLKSAG Mvan_1546|M.vanbaalenii_PYR-1 FDMGMLLAISVGYLAFVRWRIRLKSA- Mb1776|M.bovis_AF2122/97 FDMAMLVALSVIYVGFVRWKIRLKAC- Rv1747|M.tuberculosis_H37Rv FDMAMLVALSVIYVGFVRWKIRLKAC- MUL_3149|M.ulcerans_Agy99 FDMAMLAFISLCYVSFVRWKIRLKGG- MAB_3698|M.abscessus_ATCC_1997 FDMGILGLLSLVMAGFVRWRIRLKG-- MLBr_02352|M.leprae_Br4923 ---------------------------