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EPSSTDIADIDFDDLTRPVLTDVQRQVLQFTESRHVEFDIAALLAEAVDQAGVGDDLGDTDGFGNRLRAH VAAIEGDQGLTQLTRSSLRQRVVRLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPRSGTTHLVNLLAA DPRRRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTEHDALMATAPVVAAMHDRFPEAIEEEVELLDLD LASYVLEWHARVPDWRDYYLGLDQRRHYAYLKKVLQALTFLRGPQTWVLKSPQHCEQLGPLMATFPDATV AFTHRDPVAVIQSTITMMAYSDRLRRTSIDAGWLLDYWSDRVYRLLRACVRDRDIAPPDRSIDIGFHQLN GSEMALLDELYRCSGVAITPKVRGLFQQYLDGNPRGKHGRVRYHLQRHFGSSAEQLRERFDFYFDRFDVR PE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5290 | - | - | 100% (423) | hypothetical protein MMAR_5290 |
| M. marinum M | MMAR_0341 | - | 5e-72 | 40.42% (381) | hypothetical protein MMAR_0341 |
| M. marinum M | MMAR_0220 | - | 2e-33 | 30.31% (386) | hypothetical protein MMAR_0220 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 2e-28 | 27.54% (374) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4385 | - | 1e-70 | 41.21% (381) | hypothetical protein Mflv_4385 |
| M. tuberculosis H37Rv | Rv3529c | - | 2e-28 | 27.54% (374) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 2e-41 | 30.92% (359) | putative sulfotransferase |
| M. avium 104 | MAV_0335 | - | 0.0 | 79.14% (417) | hypothetical protein MAV_0335 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 2e-29 | 26.44% (382) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 6e-26 | 25.93% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4363 | - | 0.0 | 98.82% (423) | hypothetical protein MUL_4363 |
| M. vanbaalenii PYR-1 | Mvan_1960 | - | 7e-76 | 40.05% (422) | hypothetical protein Mvan_1960 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5930|M.smegmatis_MC2_155 ------------------------MGTVEDLHASATKATGLDDFGTDDDN
TH_0375|M.thermoresistible__bu ---------------MTPR---TDVGTVEDLHASAVKACGLEDFGSDDDN
Mb3559c|M.bovis_AF2122/97 ---------------MTRRPDRKDVATVDELHASATKLVGLDDFGTDDDN
Rv3529c|M.tuberculosis_H37Rv ---------------MTRRPDRKDVATVDELHASATKLVGLDDFGTDDDN
MAB_3968|M.abscessus_ATCC_1997 ---------------MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQ
MMAR_5290|M.marinum_M MEPSSTDIADIDFDDLTRPVLTDVQRQV--LQFTESRHVEFDIAALLAEA
MUL_4363|M.ulcerans_Agy99 MEPSSTDIADIDFDDLTRPVLTDVQRQV--LQFTESRHVEFDIAALLAEA
MAV_0335|M.avium_104 ---MGSAVDDIDFDDLTSPRLTDVQRQI--LEFTEAKPVDLDIDRMLAEA
Mflv_4385|M.gilvum_PYR-GCK -------------------------------MASLAADCPLDAEVLHTRA
Mvan_1960|M.vanbaalenii_PYR-1 --MTDTTDGFIHLDDLAEPRYSPAAQQLREMMATLAADCPLDTDILHARA
:
MSMEG_5930|M.smegmatis_MC2_155 YR-------------------EALGVLLESYQRDAHLTELGSKMSRFFLR
TH_0375|M.thermoresistible__bu YK-------------------EALAVLLDSYQREADLTELGSKMSRFFLR
Mb3559c|M.bovis_AF2122/97 YR-------------------EALGVLLDAYQGEAGLTVLGSKMNRFFLR
Rv3529c|M.tuberculosis_H37Rv YR-------------------EALGVLLDAYQGEAGLTVLGSKMNRFFLR
MAB_3968|M.abscessus_ATCC_1997 WLRSAARRATGLEWVADAYLDDALEVLAASLRNDAKLSFLGRKMVQVRLV
MMAR_5290|M.marinum_M VDQAGV----GDDLGDTDGFGNRLRAHVAAIEGDQGLTQLTRSSLRQRVV
MUL_4363|M.ulcerans_Agy99 VDQAGV----GDDLGDTDGFGNRLRAHVAAIEGDQGLTQLTRSSLRQRVV
MAV_0335|M.avium_104 IEQAGLP---GADLDDTHGFVDRLHVHVAAIEADHGLRQLTRGSLRQRVV
Mflv_4385|M.gilvum_PYR-GCK REATGL-----DDFGPDD-YRERLEMYLAELR-EIDMHAPGVVNFHVQLV
Mvan_1960|M.vanbaalenii_PYR-1 REATGL-----DDFGPQD-YRERLDRYVAELR-EIDMHGPGIVNFHAQLV
: * . : : : :
MSMEG_5930|M.smegmatis_MC2_155 NALVARLLSEASWKANPQYADVEIERPIFVTGLPRTGTTVLHRLLTADPA
TH_0375|M.thermoresistible__bu NALVARLVSEAAWKQYPQHADVVIERPIFVTGLPRTGTTALHRLLAADPA
Mb3559c|M.bovis_AF2122/97 GALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPA
Rv3529c|M.tuberculosis_H37Rv GALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPA
MAB_3968|M.abscessus_ATCC_1997 GMLSTRLRLRELIRKNPGIAQLPVEPPIVIVGLQRTGTTLLHRLLAADPS
MMAR_5290|M.marinum_M RLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPRSGTTHLVNLLAADPR
MUL_4363|M.ulcerans_Agy99 RLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPRSGTTHLVNLLAADPR
MAV_0335|M.avium_104 RLLRNRLSLTELLQRYPEIESIPIEQPFIVVGMPRSGTTHLVNLIACDPR
Mflv_4385|M.gilvum_PYR-GCK QWLKNRLLLTDLLTRHPEIEEIELLPPVVIAGLPRSGTTHLHNLLAAAPT
Mvan_1960|M.vanbaalenii_PYR-1 QWLKNRLLLTDLLARHPEIEDIELVAPVVIAGLPRSGTTHLHNMLASAPT
* ** * .: : *..:.*: *:*** * .:: . *
MSMEG_5930|M.smegmatis_MC2_155 HQGLEMWLAEFPQPRPPRET--WPDNPVYQQLAASFSQHHQENPDYTGLH
TH_0375|M.thermoresistible__bu HQGLELWLAEFPQPRPPRET--WPDNPIYRQLEAQFTKAHQENPDYTGLH
Mb3559c|M.bovis_AF2122/97 HQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQFTQHHAENPGYTGLH
Rv3529c|M.tuberculosis_H37Rv HQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQFTQHHAENPGYTGLH
MAB_3968|M.abscessus_ATCC_1997 AGSMSSWEGASPLPHPEQPS--GAPDLRIAQAAKDERSLRYLAPQFFAIH
MMAR_5290|M.marinum_M RRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTEHDALMATAPVVAAMH
MUL_4363|M.ulcerans_Agy99 RRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTEHDALMATAPVVAAMH
MAV_0335|M.avium_104 RRALPYWESQEPIPARGQGPDVFGVDPRYARAKAEHEALMASAPVVAAMH
Mflv_4385|M.gilvum_PYR-GCK FRSLPYWESVEPFPLPAEQG--VEPDPRIGRMDLALQTMDLLMPHFALMH
Mvan_1960|M.vanbaalenii_PYR-1 FRSLPYWESVEPFPLPAEAG--IEPDPRVGRMDVAVQTMDLLMPHFALMH
.: * . * * . : : * :*
MSMEG_5930|M.smegmatis_MC2_155 FMTADEVEECWQLLRQSLHSVSYETLAHLPTYANWLAQQDWTRPYQRHRR
TH_0375|M.thermoresistible__bu FMTAGEVEECWQLLRQSVHSVSYETLAHVPSYARWLARQDWTKPYQRHRR
Mb3559c|M.bovis_AF2122/97 FMAAYELEECWQLLRQSLHSVSYEALAHVPSYADWLSRQDWTPSYCRHRR
Rv3529c|M.tuberculosis_H37Rv FMAAYELEECWQLLRQSLHSVSYEALAHVPSYADWLSRQDWTPSYCRHRR
MAB_3968|M.abscessus_ATCC_1997 SVEAEAPEEDVLLLDFALHSQMPEVMFHVPGYAKWLADQDMTPAYELHRL
MMAR_5290|M.marinum_M DRFPEAIEEEVELLDLDLASYVLEWHARVPDWRDYYLGLDQRRHYAYLKK
MUL_4363|M.ulcerans_Agy99 DRFPEAIEEEVELLDLDLASYVLEWHARVPDWRDYYLGLDQRRHYAYLKK
MAV_0335|M.avium_104 DRFPEAIEEEVELLDLDLASYVLEWHARVPAWRDHYLSLDQTRHYAYLKK
Mflv_4385|M.gilvum_PYR-GCK EMTTDHAHEEIQLLANDFSTMLMETLAHVPRWTEYYWNRDQTPTYEYLVT
Mvan_1960|M.vanbaalenii_PYR-1 EMTTDHVHEEIQLLANDFSTMLMDTLAHVPRWTDYFWSTDQTSSYRYLVT
. .* ** . : : ::* : * *
MSMEG_5930|M.smegmatis_MC2_155 NLQLIGLNDAEKRWVLKNPSHLFALDALFATYPDALVIQCHRPAETIMAS
TH_0375|M.thermoresistible__bu NLQLIGLNDVEKRWVLKNPSHLFALDALFATYPDALVVQCHRPAETIMAS
Mb3559c|M.bovis_AF2122/97 NLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDALVVQTHRPVETIMAS
Rv3529c|M.tuberculosis_H37Rv NLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDALVVQTHRPVETIMAS
MAB_3968|M.abscessus_ATCC_1997 LLQVLQWQQPRGRWVLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTAS
MMAR_5290|M.marinum_M VLQALTFLRGPQTWVLKSPQHCEQLGPLMATFPDATVAFTHRDPVAVIQS
MUL_4363|M.ulcerans_Agy99 VLQALTFLRGPQTWVLKRPQHCEQLGPLMATFPDATVAFTHRDPVAVIQS
MAV_0335|M.avium_104 VLQALTFLRGPRTWVLKSPQHCEQLGPLMATFPDATIAFTHRDPVAVIQS
Mflv_4385|M.gilvum_PYR-GCK QLKALQFLRGGGRWVLKSPQHLAQLPVIGRVLPGVRVVFTHRDPVPVALS
Mvan_1960|M.vanbaalenii_PYR-1 QLKALQFLRGGRRWILKSPQHLGQLPVLDEVMPGVVVVFTHRDPVPVALS
*: : *:** * * * : . *.. : ** *
MSMEG_5930|M.smegmatis_MC2_155 MCSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEAFTAERAKHDPAQFLD
TH_0375|M.thermoresistible__bu MCSLSQHTTAGWSNTFVGAQIGADAMETWTRGLRLFNEARANYDPAQFHD
Mb3559c|M.bovis_AF2122/97 MCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLERFNAARAKYDSAQFYD
Rv3529c|M.tuberculosis_H37Rv MCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLERFNAARAKYDSAQFYD
MAB_3968|M.abscessus_ATCC_1997 SSSMLAHYQALFSDRVDHHELARYWLGKNAQIIDRAIAVRAEHP-AAFVD
MMAR_5290|M.marinum_M TITMMAYSDRLRRTSIDAGWLLDYWSDRVYRLLRACVRDRDIAPPDRSID
MUL_4363|M.ulcerans_Agy99 TITMMAYSDRLRRTSIDAGWLLDYWSDRVYPLLWACVRDRDIVPPDRSID
MAV_0335|M.avium_104 AITMMAYSDRLRRTSIDPQWLLDYWSDRVHRLLSACVRDRDLVAPERSVD
Mflv_4385|M.gilvum_PYR-GCK MIAMVTYSARMHRDHVDVPVVAAAWVDRLEKLLDACVRDREVIAPDRSLD
Mvan_1960|M.vanbaalenii_PYR-1 MIAMVTYSERMHRDKVDVPTVARAWVDRLEHLLNACVRDRDIIPTERSAD
:: : . : : * *
MSMEG_5930|M.smegmatis_MC2_155 VDYDDFVADPLATVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPKHT
TH_0375|M.thermoresistible__bu VEYADFVKDPIGTVEGIYRHFGLEFTDAARDAMTRLHTESQRGPRAPRHS
Mb3559c|M.bovis_AF2122/97 VDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHS
Rv3529c|M.tuberculosis_H37Rv VDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHS
MAB_3968|M.abscessus_ATCC_1997 INYTELLDDPIAAVQRIYHAADRRLSDDALTAMRVSLQQNRQHKHG-EHR
MMAR_5290|M.marinum_M IGFHQLNGSEMALLDELYRCSGVAITPKVRGLFQQYLDGNPRGKHGRVRY
MUL_4363|M.ulcerans_Agy99 IGFHQLNGNEMALLDELYRCSGVAITPKVRGLFQQYLDGNPRGKHGRVRY
MAV_0335|M.avium_104 ISFHQLSGNEIPVIERLYERGGVELPQRVRDRFQRYLDGNPRGKHGRIRY
Mflv_4385|M.gilvum_PYR-GCK VRFDDFMADELGVAESIYALTGEDFDGRSRAAVAQYLQSHRRGRHGRV-H
Mvan_1960|M.vanbaalenii_PYR-1 ITFDAFMADEIGTAERVYRVAGEPLTEESRSAIGRYLDGHRRGRHGRV-Y
: : : . : :* . . :.
MSMEG_5930|M.smegmatis_MC2_155 YSLADYGLTSEAVKERFTGL---------------------
TH_0375|M.thermoresistible__bu YSLADYGLTAESVRDAFSGL---------------------
Mb3559c|M.bovis_AF2122/97 YSLADYGLTVEMVKERFAGL---------------------
Rv3529c|M.tuberculosis_H37Rv YSLADYGLTVEMVKERFAGL---------------------
MAB_3968|M.abscessus_ATCC_1997 YSLAQFGLTIAEVDAAYRRYIDHFAIQTERGGVRGDR----
MMAR_5290|M.marinum_M HLQRHFGSSAEQLRERFDFYFDRFDVRPE------------
MUL_4363|M.ulcerans_Agy99 HLQRHFGSSAEQLRERFDFYFDRFDVRPE------------
MAV_0335|M.avium_104 QLQRHFGISADELRARFGFYFDKFDVRPE------------
Mflv_4385|M.gilvum_PYR-GCK TSADMFGLDPEELRERFAPYS------------ARFLS---
Mvan_1960|M.vanbaalenii_PYR-1 TSAEMFGLDPEELRDRFTPYMGWMRNRPARCSQAKVTSALG
:* : :