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M. avium 104 MAV_0593 (-)

annotation: extradiol ring-cleavage dioxygenase
coordinates: 577401 - 578312
length: 303

MSNGAIRSLGYLRIEATDMAAWRDYGLKVLGMVEGKGDTEGALYLRMDDFPARLVIVPGERDHLLEAGWE
CANAEGLQEIRDRLDMEGVPYKEATAAQLADRRVVEMIRFSDPSGNCLEVFHGVALEHRRVVSPYGHKFV
TGEQGLGHVVLSTRDDEESLHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNPRHHSLAFLPL
PTPSGIVHLMLEVENADDVGLCLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVEDD
DWVARESTAVSLWGHDFTVGMRG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0593--100% (303)extradiol ring-cleavage dioxygenase
M. avium 104MAV_3021-5e-7545.58% (294) biphenyl-2,3-diol 1,2-dioxygenase 1
M. avium 104MAV_2516-4e-3430.38% (293) extradiol ring cleaving catechol dioxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3599cbphC1e-16389.30% (299) putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP
M. gilvum PYR-GCKMflv_1465-1e-14883.50% (297) glyoxalase/bleomycin resistance protein/dioxygenase
M. tuberculosis H37RvRv3568cbphC1e-16389.63% (299) biphenyl-2,3-diol 1,2-dioxygenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0585-1e-12870.71% (297) 2,3-dihydroxybiphenyl 1,2-dioxygenase
M. marinum MMMAR_5063bphC1e-16390.64% (299) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. smegmatis MC2 155MSMEG_6036-1e-14580.87% (298) biphenyl-2,3-diol 1,2-dioxygenase
M. thermoresistible (build 8)TH_1740-1e-15685.95% (299) PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP
M. ulcerans Agy99MUL_4139bphC1e-16390.64% (299) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. vanbaalenii PYR-1Mvan_5306-1e-14783.16% (297) glyoxalase/bleomycin resistance protein/dioxygenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1465|M.gilvum_PYR-GCK          MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGPTEGALYLRMDEF
Mvan_5306|M.vanbaalenii_PYR-1       MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGSTEGALYLRMDEF
MSMEG_6036|M.smegmatis_MC2_155      MS---IKSLGYLRIEATDVAAWREYGLKVLGMVEGKGNTDGALYLRMDEF
MMAR_5063|M.marinum_M               MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
MUL_4139|M.ulcerans_Agy99           MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
Mb3599c|M.bovis_AF2122/97           MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
Rv3568c|M.tuberculosis_H37Rv        MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
MAV_0593|M.avium_104                MSNGAIRSLGYLRIEATDMAAWRDYGLKVLGMVEGKGDTEGALYLRMDDF
TH_1740|M.thermoresistible__bu      MS---IRSLGYLRIEATDVAAWREYGLKVLGMVEGKGPTEGALYLRMDEF
MAB_0585|M.abscessus_ATCC_1997      MS--IIKALGYMRIQATDVAAWREFGTKVLGMMEGTGDDPAALYLRMDDF
                                    *:   *::***:**::**:****::* *****:**.*   .*******:*

Mflv_1465|M.gilvum_PYR-GCK          PARLIIVPGENDRLLESGWETANAAALQDIRARLDIHGTPYKEATASQLA
Mvan_5306|M.vanbaalenii_PYR-1       PARLVIVPGERDRLLVSGWETANASQLQDIRKRLEVEGTPYKEATATQLA
MSMEG_6036|M.smegmatis_MC2_155      PARLVIVPGEHDRLQVSGWEAANAAELQDIRSRLDAAGTPFKEGTSAELA
MMAR_5063|M.marinum_M               PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
MUL_4139|M.ulcerans_Agy99           PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
Mb3599c|M.bovis_AF2122/97           PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
Rv3568c|M.tuberculosis_H37Rv        PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
MAV_0593|M.avium_104                PARLVIVPGERDHLLEAGWECANAEGLQEIRDRLDMEGVPYKEATAAQLA
TH_1740|M.thermoresistible__bu      PARLVIVPGERDRLLESGWECANAEGLQDVRSRLEAAGVPYKEGTAAELA
MAB_0585|M.abscessus_ATCC_1997      AARLVIVPGESDRLLASGWEVADAPALQAVRERLAKAGVEYAEGDKAEVS
                                    .***::***  *:*  :*** *:*  ** :* **   *. : *.  ::::

Mflv_1465|M.gilvum_PYR-GCK          DRRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
Mvan_5306|M.vanbaalenii_PYR-1       ERRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
MSMEG_6036|M.smegmatis_MC2_155      ERRVDEMIVFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
MMAR_5063|M.marinum_M               DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
MUL_4139|M.ulcerans_Agy99           DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
Mb3599c|M.bovis_AF2122/97           DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
Rv3568c|M.tuberculosis_H37Rv        DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
MAV_0593|M.avium_104                DRRVVEMIRFSDPSGNCLEVFHGVALEHRRVVSPYGHKFVTGEQGLGHVV
TH_1740|M.thermoresistible__bu      DRRVVELIRFQDPSGNTLEAFHTVALEHRRVVSPYGHRFVTGEQGLGHVV
MAB_0585|M.abscessus_ATCC_1997      DRKVEAFIQFSDPSGNTLEVFHGAQYMGRRFVSPYGHKFVTAEQGLGHVV
                                    :*:*  :* * ***** * .** .    **.******:*** ***:****

Mflv_1465|M.gilvum_PYR-GCK          LTTRDDAETLHFYRDVLGFFLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
Mvan_5306|M.vanbaalenii_PYR-1       LTTRDDAETLHFYRDVLGFYLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
MSMEG_6036|M.smegmatis_MC2_155      LTTKDDRETLHFYRDILGFSLRDSMKLPPQLVGRPADGEPAWLRFLGVNP
MMAR_5063|M.marinum_M               LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
MUL_4139|M.ulcerans_Agy99           LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
Mb3599c|M.bovis_AF2122/97           LSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLRFFGCNP
Rv3568c|M.tuberculosis_H37Rv        LSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLRFFGCNP
MAV_0593|M.avium_104                LSTRDDEESLHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
TH_1740|M.thermoresistible__bu      LTTRDDAESLRFYRDVLGFYLRDSMRLPPQLVGRPADGEPAWLRFFGCNP
MAB_0585|M.abscessus_ATCC_1997      LTCTDDVAAQEFYQDVLGFQLRDSMKLPPQLVGRPADGDPVWLRFYGCNP
                                    *:  **  : .**:*:*** *****::**::******* *.**** * **

Mflv_1465|M.gilvum_PYR-GCK          RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
Mvan_5306|M.vanbaalenii_PYR-1       RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
MSMEG_6036|M.smegmatis_MC2_155      RHHSLAFMPGQTPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
MMAR_5063|M.marinum_M               RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
MUL_4139|M.ulcerans_Agy99           RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
Mb3599c|M.bovis_AF2122/97           RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
Rv3568c|M.tuberculosis_H37Rv        RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
MAV_0593|M.avium_104                RHHSLAFLPLPTPSGIVHLMLEVENADDVGLCLDRALRRKVPMSATLGRH
TH_1740|M.thermoresistible__bu      RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVPMSATLGRH
MAB_0585|M.abscessus_ATCC_1997      RHHALAFMPMPNPTGIVHLMVEVENSDDVGLCLDRANRRKVKMSATLGRH
                                    ***:***:*  ..:******:**:::********** **** ********

Mflv_1465|M.gilvum_PYR-GCK          VNDKMLSFYMKTPGGFDVEFGCEGLEVDDQNWVARESTAVSLWGHDFSVG
Mvan_5306|M.vanbaalenii_PYR-1       VNDKMLSFYMKTPGGFDIEFGCEGLEVDDENWVARESTAVSLWGHDFSVG
MSMEG_6036|M.smegmatis_MC2_155      VNDKMLSFYMKTPGGFDIEFGCEGLEVDDDNWVARESTAVSLWGHDFSVG
MMAR_5063|M.marinum_M               VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
MUL_4139|M.ulcerans_Agy99           VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
Mb3599c|M.bovis_AF2122/97           VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
Rv3568c|M.tuberculosis_H37Rv        VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
MAV_0593|M.avium_104                VNDLMLSFYMKTPGGFDVEFGCEGRQVEDDDWVARESTAVSLWGHDFTVG
TH_1740|M.thermoresistible__bu      VNDKMLSFYMKTPGGFDVEFGCEGLQVDDEEWVARESTAVSLWGHDFSIG
MAB_0585|M.abscessus_ATCC_1997      INDKMLSFYMKTPGGFDMEFGCEGMEVDDESWVARESVGVSLWGHDFSVG
                                    :** *************:****** :*:* .*:****..********::*

Mflv_1465|M.gilvum_PYR-GCK          FK-
Mvan_5306|M.vanbaalenii_PYR-1       FKS
MSMEG_6036|M.smegmatis_MC2_155      FK-
MMAR_5063|M.marinum_M               ARG
MUL_4139|M.ulcerans_Agy99           ARG
Mb3599c|M.bovis_AF2122/97           ARG
Rv3568c|M.tuberculosis_H37Rv        ARG
MAV_0593|M.avium_104                MRG
TH_1740|M.thermoresistible__bu      FKG
MAB_0585|M.abscessus_ATCC_1997      FK-
                                     :