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MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHPCLQSRIAAAWLWSRGSATVGGAAAAAL HGAKWIPEDVPVELICARSRPPRGVLTRRDVLIDGETQFLGGYSVTTAERTAFDIGRRGAMRSAVVRLDA LARATGFTVADVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLIDAGLPRPQTQLPVLGVNG MPVAYLDMGWERYMVAVEYDGDHHRSDRQQYVKDIRRGEMLERMGWIVIRVVAEDRRVDILRRVTAALDE RRSAVP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0712 | - | - | 100% (286) | hypothetical protein MMAR_0712 |
| M. marinum M | MMAR_0375 | - | 4e-72 | 50.73% (274) | hypothetical protein MMAR_0375 |
| M. marinum M | MMAR_5026 | - | 3e-70 | 48.57% (280) | hypothetical protein MMAR_5026 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1102 | - | 2e-85 | 55.31% (273) | hypothetical protein Mb1102 |
| M. gilvum PYR-GCK | Mflv_4812 | - | 2e-67 | 47.62% (273) | hypothetical protein Mflv_4812 |
| M. tuberculosis H37Rv | Rv1073 | - | 2e-85 | 55.31% (273) | hypothetical protein Rv1073 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 6e-68 | 47.84% (278) | hypothetical protein MAB_2184 |
| M. avium 104 | MAV_4752 | - | 1e-106 | 69.96% (273) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0785 | - | 3e-95 | 59.22% (282) | hypothetical protein MSMEG_0785 |
| M. thermoresistible (build 8) | TH_3202 | - | 1e-68 | 52.46% (244) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2811 | - | 1e-163 | 99.30% (286) | hypothetical protein MUL_2811 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 1e-67 | 48.35% (273) | hypothetical protein Mvan_5526 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0712|M.marinum_M MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHPCLQSRIA
MUL_2811|M.ulcerans_Agy99 MCDLRAPFIGSKALACGAVTRHQLRTRYRPVLPNVYLSAGVHPCLQSRIA
MAV_4752|M.avium_104 MG--EAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLPAQVEPTLPLRIR
MSMEG_0785|M.smegmatis_MC2_155 ---MTAPFLGSEALADGTLNRHQLRTRFRTLYPNVYVPKTSEPTLEQRTV
Mb1102|M.bovis_AF2122/97 --MGAQPFIGSEALAAGLISWHELGKYYTAIMPNVYLDKRLKPSLRQRVI
Rv1073|M.tuberculosis_H37Rv --MGAQPFIGSEALAAGLISWHELGKYYTAIMPNVYLDKRLKPSLRQRVI
TH_3202|M.thermoresistible__bu ----------------------------------VYTQREARLTLGQRVH
MAB_2184|M.abscessus_ATCC_1997 ---MAAVFVGSEAVSAGQLTRHELQRFYRPIFRGVYLPKSAEPTLRDRTV
Mvan_5526|M.vanbaalenii_PYR-1 MPGMGEVILGGEAVRAGVVTRHELARWYTPLYRGVFVRKGVEVTLRDRAV
Mflv_4812|M.gilvum_PYR-GCK ---MGDIIIGTEAVANGTVTRHQLQRWYRPIFTNIHAPRGPAPTLGDRAV
:. * *
MMAR_0712|M.marinum_M AAWLWSRGSATVGGAAAAALHGAKWIPEDVPVELICARSRPPRGVLTRRD
MUL_2811|M.ulcerans_Agy99 AAWLWSRGSATVGGAAAAALHGAKWIPEDVPVELICARSSPPRGVLTRRD
MAV_4752|M.avium_104 AAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHHNTRAPDGVLIRRD
MSMEG_0785|M.smegmatis_MC2_155 GAWLWSGRRAVIAGPAAAALHGAKWIDPSIPIDLIHDNPRQPRGITTRRD
Mb1102|M.bovis_AF2122/97 AAWLWSGRKGVIAGASASALHGAKWVDDHALVELIWRNARAPNGVRTKDE
Rv1073|M.tuberculosis_H37Rv AAWLWSGRKGVIAGASASALHGAKWVDDHALVELIWRNARAPNGVRTKDE
TH_3202|M.thermoresistible__bu AAWLWSRRRGTIAGSAAAAVHGTKWIDVDTPVELVHTNPRPPDGIVTRRC
MAB_2184|M.abscessus_ATCC_1997 AAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGVKCRQQEGLIARNE
Mvan_5526|M.vanbaalenii_PYR-1 GAWLATGRKGVIAGLAAAALHGAAWIDADIPIEVAGVKRRSHAGLITRSE
Mflv_4812|M.gilvum_PYR-GCK GAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYKCPRPPSGIVARND
.*** : . : * :*: :**: *: ::: *: :
MMAR_0712|M.marinum_M VLIDGETQFLGGYSVTTAERTAFDIGRRGAMRSAVVRLDALARATGFTVA
MUL_2811|M.ulcerans_Agy99 VLIDGETQFLGGYSVTTAERTAFDIGRRGAMRSAVVRLDALARATGFTVA
MAV_4752|M.avium_104 GLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVRLDSLARATGFKAD
MSMEG_0785|M.smegmatis_MC2_155 TLLPGETVVIGGMLLTSSARTAFDIGRRSPTNRGVAHLDALLRATGCTVA
Mb1102|M.bovis_AF2122/97 LLLDGEVQRLCGLTVTTVERTAFDLGRRPPLGQAITRLDALANATDFKIN
Rv1073|M.tuberculosis_H37Rv LLLDGEVQRLCGLTVTTVERTAFDLGRRPPLGQAITRLDALANATDFKIN
TH_3202|M.thermoresistible__bu LLFDDEVTTIDGRPVTTPERTAFDIGRRGSIMSTVPRLDALVNATGIKLD
MAB_2184|M.abscessus_ATCC_1997 RIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGCLDALMRNQVFALD
Mvan_5526|M.vanbaalenii_PYR-1 VIATDEIVRRAGLPVTSRTRTAFDLGRQLDRAEALARLDALMWNQPFSID
Mflv_4812|M.gilvum_PYR-GCK RIDPDEWQSIDGLPVATAARTAFDLGRYRPEHDALARLDALMAVRPYSVE
: .* * :: *****:** : **:*
MMAR_0712|M.marinum_M DVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLIDAGLPRPQ
MUL_2811|M.ulcerans_Agy99 DVLQVARNHRGTRGLRQLETALELVDPGAQSPRESYLRLFLIDAGLPRPQ
MAV_4752|M.avium_104 DVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYLRLLLIDAGLPRPQ
MSMEG_0785|M.smegmatis_MC2_155 DIADLANRHRGARGLRRLEATLPLVDAGAQSPKETWLRLLIVRDGLPKPT
Mb1102|M.bovis_AF2122/97 DVRELARKHPHTRGLRQLDKALDLVDPGAQSPKETWLRLLLINAGFPRPS
Rv1073|M.tuberculosis_H37Rv DVRELARKHPHTRGLRQLDKALDLVDPGAQSPKETWLRLLLINAGFPRPS
TH_3202|M.thermoresistible__bu DIARLAARHPGARGLRLLETVLELVDGGAQSPKESQVRLWLIEAGFPVPH
MAB_2184|M.abscessus_ATCC_1997 EVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLIRLQLRDAGLPRAQ
Mvan_5526|M.vanbaalenii_PYR-1 EVAELADRRPRVPGVGQLRDLLPLIDGGAASPRQSRLRLWLLDCGFPRPQ
Mflv_4812|M.gilvum_PYR-GCK DVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWWRKLVLDSGFPPPR
:: :: *: * * ::* ** **::: * : *:* .
MMAR_0712|M.marinum_M TQLPVLGVNGMPVAYLDMGWERYMVAVEYDGDHHRSDRQQYVKDIRRGEM
MUL_2811|M.ulcerans_Agy99 TQLPVLGVNGMPVAYLDMGWERYMVAVEYDGDHHRSDRQQYVKDIRRGEM
MAV_4752|M.avium_104 TQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTDRRQYVKDIRRLEM
MSMEG_0785|M.smegmatis_MC2_155 TQIPVLADDGTPLAYLDMGWEEWMVAVEYDGDQHRTDRRQYVRDIRRLEL
Mb1102|M.bovis_AF2122/97 TQIPLLGVYGHPKYFLDMGWEDIMLAVEYDGEQHRLSRDQFVKDVERLEY
Rv1073|M.tuberculosis_H37Rv TQIPLLGVYGHPKYFLDMGWEDIMLAVEYDGEQHRLSRDQFVKDVERLEY
TH_3202|M.thermoresistible__bu TQIPVCDSDGVPFAFLDMGWPEWLLAVEYEGEHHR-ERFRYTGDIHRLEK
MAB_2184|M.abscessus_ATCC_1997 TQVPVFDGY-TPIAFLDIGWPQYLVAVEYDGDHHRRDRRQYVKDLARLRM
Mvan_5526|M.vanbaalenii_PYR-1 TQIPVLEGS-RPVAFLDMGWPEYQVAVEYDGDHHRKNRDQYVKDIARLRM
Mflv_4812|M.gilvum_PYR-GCK TQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSDRAQYLKDRRVMPA
**:*: **:** :****:*::*: .* :: *
MMAR_0712|M.marinum_M LERMGWIVIRVVAEDRRVDILRRVTAALDERRSAVP--------------
MUL_2811|M.ulcerans_Agy99 LERMGWIVIRVVAEDRRVDILRRVTAALAERRSAVP--------------
MAV_4752|M.avium_104 LEQLGWVIVRVVAEDRPADIVRRVRAALAKSGVAPRLSV-----------
MSMEG_0785|M.smegmatis_MC2_155 LAELGWIVIRVVAEDGTAEILRRIRAALTARQSTVRSGRKAS--------
Mb1102|M.bovis_AF2122/97 IRRAGWTHIRVLADHKGPDVVRRVRQAWDTLTSRR---------------
Rv1073|M.tuberculosis_H37Rv IRRAGWTHIRVLADHKGPDVVRRVRQAWDTLTSRR---------------
TH_3202|M.thermoresistible__bu VQQQ-WSVVRLTADDTQVSAIHRVHRAVSALGVNCPCRL-----------
MAB_2184|M.abscessus_ATCC_1997 LEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEIDEMQRSTRPFAA-
Mvan_5526|M.vanbaalenii_PYR-1 LEALGWIVIRVIAEDRPAHWLERTEAALQSRGCRLAATELQLFVRTLAA-
Mflv_4812|M.gilvum_PYR-GCK LRRLGWHVTTVVKEDDPVAVIQTLSAAMRARGWRGSIQIPRYAYTTRFRA
: * : :. : *
MMAR_0712|M.marinum_M ----------
MUL_2811|M.ulcerans_Agy99 ----------
MAV_4752|M.avium_104 ----------
MSMEG_0785|M.smegmatis_MC2_155 ----------
Mb1102|M.bovis_AF2122/97 ----------
Rv1073|M.tuberculosis_H37Rv ----------
TH_3202|M.thermoresistible__bu ----------
MAB_2184|M.abscessus_ATCC_1997 ----------
Mvan_5526|M.vanbaalenii_PYR-1 ----------
Mflv_4812|M.gilvum_PYR-GCK EIASRQEKCE