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M. thermoresistible (build 8) TH_1201 (-)

annotation: xanthine/uracil permease
coordinates: 2294674 - 2296086
length: 471

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1201--100% (471)xanthine/uracil permease
M. thermoresistible (build 8)TH_2104-2e-0823.88% (402) sulfate permease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3301-8e-0625.71% (245) transmembrane carbonic anhydrase
M. gilvum PYR-GCKMflv_0346-0.077.45% (470) xanthine/uracil/vitamin C permease
M. tuberculosis H37RvRv3273-8e-0625.71% (245) transmembrane carbonic anhydrase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3353c-1e-14658.02% (474) putative xanthine/uracil/vitamin C permease family protein
M. marinum MMMAR_1266sulP_27e-0824.71% (425) transmembrane carbonic anhydrase, SulP_2
M. avium 104MAV_0121-1e-1124.76% (416) carbonate dehydratase
M. smegmatis MC2 155MSMEG_0564-0.080.85% (470) xanthine/uracil permease
M. ulcerans Agy99MUL_5080sulP5e-0821.23% (405) transmembrane carbonic anhydrase, SulP
M. vanbaalenii PYR-1Mvan_0392-0.080.00% (470) xanthine/uracil/vitamin C permease

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0346|M.gilvum_PYR-GCK          ---------------MNSVDRFFEITARQSTLGTEIRGGVVTFIAMAYII
Mvan_0392|M.vanbaalenii_PYR-1       ---------------MNPVDRFFEITARQSSVATEIRGGVVTFIAMAYII
MSMEG_0564|M.smegmatis_MC2_155      ---------------MNRLDRFFDITARGSTLTAEIRGGVVTFIAMAYII
TH_1201|M.thermoresistible__bu      ---------------VNRLDRFFEISARGSTVSTEVRGGLVTFIAMAYII
MAB_3353c|M.abscessus_ATCC_199      --------------MTALLDRFFRITERQSTLGREIRGGVVTFFAMAYIV
Mb3301|M.bovis_AF2122/97            --------------MTIPRSQHMSTAVNSCTEAPASRSQWMLANLRHDVP
Rv3273|M.tuberculosis_H37Rv         --------------MTIPRSQHMSTAVNSCTEAPASRSQWMLANLRHDVP
MMAR_1266|M.marinum_M               ----------------------MSTAVKNSAEAPESRSQWMRANLRHDFP
MAV_0121|M.avium_104                --------------------------------MSTSRSERLREVLRYDLP
MUL_5080|M.ulcerans_Agy99           MPHIEQPDKQSLDHAQHPGTPEPPTTSRLSRVSQISRPDRVRSVIRHDLP
                                                                        *   :       . 

Mflv_0346|M.gilvum_PYR-GCK          VLNPIILSGSE------DVTGAKLDFAQVSATTSLAAGVMTILFGLIARL
Mvan_0392|M.vanbaalenii_PYR-1       VLNPIILSSSA------DVDGNKLDFAQVSAMTSLAAGVMTILFGVVARL
MSMEG_0564|M.smegmatis_MC2_155      VLNPVILSSAP------DVDGNNLEFAQVSAVTSLAAGVMTILFGLVARL
TH_1201|M.thermoresistible__bu      VLNPIILSGSA------DVDGNRLGFAQVSAATALTAGVMTILFGVVARL
MAB_3353c|M.abscessus_ATCC_199      VLNPLIIGGEPGRAHNVDVLGHVLPVGQVAAVTALAAGVMSILFGFVANY
Mb3301|M.bovis_AF2122/97            ASLVVFLVALP------LSLGIAIASGAPIIAGVIAAVVGGIVAGAVGGS
Rv3273|M.tuberculosis_H37Rv         ASLVVFLVALP------LSLGIAIASGAPIIAGVIAAVVGGIVAGAVGGS
MMAR_1266|M.marinum_M               ASLVVFLVALP------LSLGIAIASGAPLMAGLIAAVVGGIVAGLLGGS
MAV_0121|M.avium_104                ASLVVFLVALP------LSLGIAIASDAPVLAGLIAAIVGGIVGGWLGGS
MUL_5080|M.ulcerans_Agy99           ASLVVFLVALP------LSLGIAIASDAPVLAGLIAAVVGGIIGGALGGS
                                    .   ::: .           *  :          ::* *  *: * :.  

Mflv_0346|M.gilvum_PYR-GCK          PFALAAGLGINSFLATTVVGDLTWAEAMGLVVINGLLIVLLAVTGLRRLV
Mvan_0392|M.vanbaalenii_PYR-1       PFALAAGLGINSFLATTVVGSLTWPEAMGLVVINGLIIVLLAVTGLRRLV
MSMEG_0564|M.smegmatis_MC2_155      PFAFAAGLGINSFLATTVVGSVTWPEAMGLVVINGLIIVLLAATGLRRLV
TH_1201|M.thermoresistible__bu      PFAFAAGLGINSFLATSVVGSVSWAEAMGLVVINGLIIVLLSSTGLRRMI
MAB_3353c|M.abscessus_ATCC_199      PFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVDGLIIVALGISGFRTAV
Mb3301|M.bovis_AF2122/97            PVQVSGPAAGLTVVVAELIDELGWPMLCLMTIAAGALQIVFGLSRMARAA
Rv3273|M.tuberculosis_H37Rv         PVQVSGPAAGLTVVVAELIDELGWPMLCLMTIAAGALQIVFGLSRMARAA
MMAR_1266|M.marinum_M               SVQVSGPAAGLTVVVAGLIEQVGWQMLCLMTLGAGVLQIIFGLSRMARAA
MAV_0121|M.avium_104                PLQVSGPAAGLTVVVADVVAEFGWGVTCFITVVAGVLQVLLGFSRIARAA
MUL_5080|M.ulcerans_Agy99           PLQVSGPAAGLTVVVADLIAEFGWGITCFITAVAGLMQILLGFSRVARAA
                                    .. .:.  .  :.:.. .  .. *     :.   * : : :. : .    

Mflv_0346|M.gilvum_PYR-GCK          FDAVPMELKLGIT-AGIGLFILFIGLVDAGFIG---STGRPSPPVGLGSG
Mvan_0392|M.vanbaalenii_PYR-1       FDAVPMQLKLAIT-AGIGLFILFIGLVDAGFIS---STGVPSPPVGLGGG
MSMEG_0564|M.smegmatis_MC2_155      FDAVPMQLKLAIT-AGIGLFILFIGVVDAGFIG---STGLPSPPVGLGAG
TH_1201|M.thermoresistible__bu      FDAVPMQLKLSIT-AGIGLFILFIGLVNAGFIG---STGLPSPPTGLGVD
MAB_3353c|M.abscessus_ATCC_199      FHAIPDELKAAIA-AGIGCFIAFIGFVDAGFVRRVPDAANTTVPVGLGID
Mb3301|M.bovis_AF2122/97            LAIAPVVVHAMLAGIGITIALQQIHVLLGGTSHSSAWRNIVALPDGILHH
Rv3273|M.tuberculosis_H37Rv         LAIAPVVVHAMLAGIGITIALQQIHVLLGGTSHSSAWRNIVALPDGILHH
MMAR_1266|M.marinum_M               LAIAPVVVHAMLAGIGVTIVLQQIHVLMGGSAHSSAWRNIAALPNGILHH
MAV_0121|M.avium_104                LAISPVVVHAMLAGIGITIALQQVHVLLGGSSKSSAWSNVTGLPAQILGA
MUL_5080|M.ulcerans_Agy99           LAISPVVVHAMLAGIGITIALQQTHVLLGGESHSTAWANVVELPAQIVGA
                                    :   *  ::  ::  *:   :    .: .*             *  :   

Mflv_0346|M.gilvum_PYR-GCK          GLGSISTVPTLVFILTLLLTAALVIRKVRG---GILIGLVCGTVVAVIIE
Mvan_0392|M.vanbaalenii_PYR-1       GQGSISTVPTVIFVFTLLLTGVLVAKRVRG---GILIGLVIGTVIAVVVE
MSMEG_0564|M.smegmatis_MC2_155      GEGSINTVPTVVFVFTLLVTGILVARRVRG---GILIGLVAGTVVAVVIE
TH_1201|M.thermoresistible__bu      GGGSITTVPTVLFVATLLVTGILIARRVRG---AILIGLIGGTVVAAVIE
MAB_3353c|M.abscessus_ATCC_199      N--SVATIPTLIFAAGVLLMGILVVRKVRG---GLLIGIVAMTVVSMIAQ
Mb3301|M.bovis_AF2122/97            ELHEVIVGGTVIAILLMWSKLPAKVRIIPGPLVAIAGATVLALLPVLQTE
Rv3273|M.tuberculosis_H37Rv         ELHEVIVGGTVIAILLMWSKLPAKVRIIPGPLVAIAGATVLALLPVLQTE
MMAR_1266|M.marinum_M               ELHEVIVGGTVIAILLVWSRLPAMVRMVPGPLVAIAGATALSLMVNLDVE
MAV_0121|M.avium_104                HRPGLVLGLLVIAILVAWRWVPARLAIVPGPLVAIVVVTIISMVLPFKVS
MUL_5080|M.ulcerans_Agy99           HRPGVILGLLVIAIMVAWRWAPAKVAPVPGPLVAIVVVTVVSVVFPFHVS
                                        :     ::               : *   .:        :     .

Mflv_0346|M.gilvum_PYR-GCK          AVWHLGSAVDKPGGWSLSVPTLSGSPFALPDLSLVGEFS-LDSFGRIGVL
Mvan_0392|M.vanbaalenii_PYR-1       AIWHLGSATEKPGGWSLSVPTLSGSPFSLPDLSLVGAFS-LDSFGRIGVL
MSMEG_0564|M.smegmatis_MC2_155      AIWHLGSAVEKPGGWGLSVPSLSGSPFAMPDLSLVGEVS-LGSFSRIGAL
TH_1201|M.thermoresistible__bu      AVWHLGPAAERPGGWGLSVPALDGSPFALPDLSLIGEFS-FAGFSRIGVL
MAB_3353c|M.abscessus_ATCC_199      ALCGRGAQPTDAKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVL
Mb3301|M.bovis_AF2122/97            RIDLQGNFFDAIGLPKLAEMSPGGQPWSHEISAIALGVLTIALIASVESL
Rv3273|M.tuberculosis_H37Rv         RIDLQGNFFDAIGLPKLAEMSPGGQPWSHEISAIALGVLTIALIASVESL
MMAR_1266|M.marinum_M               RINLSGNFFEAISLPRLPELTPDGQPWSNDISIIAVGVLTIALIASVESL
MAV_0121|M.avium_104                RIELDGSVLDAVRLPSLPHGN-----WG----AVAIAVITVTLITSVQSL
MUL_5080|M.ulcerans_Agy99           RITLEGSVVDALQLPAIPHGN-----WG----AIVIGIITVTLITSVQSL
                                     :   *          :.         .     :   .  .  :  :  *

Mflv_0346|M.gilvum_PYR-GCK          AAVMLVFTLVFANFFDAMGTMTGLSREAGLSDAKGTFPRLKSALIVEGAG
Mvan_0392|M.vanbaalenii_PYR-1       AAVMLVFTLVFANFFDAMGTMTGLSREAGLSDANGTFPRLRSALVVEGAG
MSMEG_0564|M.smegmatis_MC2_155      AAIMLVFTLVFANFFDAMGTMTGLSREAGLSDPQGTFPRLKSALIVEGTG
TH_1201|M.thermoresistible__bu      AATVFVFTLVFANFFDAMGTFTGLSREAGLAGPDGTFPRLRSALVVEGVG
MAB_3353c|M.abscessus_ATCC_199      SATVLVFALVLSNFFDAMGTMTGLGKEAGLADEHGTLPGIGRALTVEGVG
Mb3301|M.bovis_AF2122/97            LSAVGVDKLHHGPRTDFNREMVGQGSANVVSGLLGGLP--ITGVIVRSSA
Rv3273|M.tuberculosis_H37Rv         LSAVGVDKLHHGPRTDFNREMVGQGSANVVSGLLGGLP--ITGVIVRSSA
MMAR_1266|M.marinum_M               LCAVGVDKLHHGPRTNFNREMLGQGSANVLSGLLGGLP--VTGVIVRSSA
MAV_0121|M.avium_104                LTAVSIDRMHTGPRTDFNRELIGQGAANIASGALGGLP--IAGVIVRSSA
MUL_5080|M.ulcerans_Agy99           LTAVATDRMHSGPTTELNRELIGQGASNVVSGAIGGLP--IAGVIVRSAA
                                       :    :  .   :    : * .     :.  * :*    .: *.. .

Mflv_0346|M.gilvum_PYR-GCK          AVVGGATSSSS---NTVFIESGAGIEEGARTGLANVVAG--VLFLAAMFI
Mvan_0392|M.vanbaalenii_PYR-1       AVVGGATSSSS---NTVFIESGAGIEEGARTGLANVVTG--LLFLAAMFV
MSMEG_0564|M.smegmatis_MC2_155      AVVGGASSASS---NTVFIESGAGIEEGARTGLANLITG--VLFLAAMFV
TH_1201|M.thermoresistible__bu      AVAGGAASASS---NTVFVESGAGIGEGARTGLANLVTG--ALFLAAMFV
MAB_3353c|M.abscessus_ATCC_199      AVIGGVSSSSS---NTVYVESASGIAEGARTGLANVVTG--LLFLAAMFF
Mb3301|M.bovis_AF2122/97            NVAAGARTRMSTILHGVWILLFASLFTNLVELIPKAALAGLLIVIGAQLV
Rv3273|M.tuberculosis_H37Rv         NVAAGARTRMSTILHGVWILLFASLFTNLVELIPKAALAGLLIVIGAQLV
MMAR_1266|M.marinum_M               NVAAGARTRTSAVLHGVWILLFASLFTGLVELIPKAALAGLLIVVGAQLI
MAV_0121|M.avium_104                NVNAGAKTRASTIMHGFWVLVFAVPFAGLVEKIPTAALAGLLIVIGIELL
MUL_5080|M.ulcerans_Agy99           NIKAGAKTRASTILHGFWVLLFALPFAGLIEQIPSAALAGLLIVIGIQLL
                                     : .*. :  *   : .::   :    .    :..   .   :.:.  :.

Mflv_0346|M.gilvum_PYR-GCK          SPLASIVPTEVAAAALVVVGAMMVSQLRHIDLTDFSVALPVVLTVAVMPF
Mvan_0392|M.vanbaalenii_PYR-1       APLASIVPTEVAAAALVVVGAMMVSHLRHIDLSEFSVALPVVLTVAVMPF
MSMEG_0564|M.smegmatis_MC2_155      APLASVVPTEVAAAALVVVGAMMVSHLRHIDLSEFSVALPVVLTVATMAF
TH_1201|M.thermoresistible__bu      SPLASVVPTEVAAAALVVVGAMMVSHLRHVDITEFSVALPVVLTVVSMPF
MAB_3353c|M.abscessus_ATCC_199      TPLYSVVPLEAAAPALVVVGAMMIGQLRSVDLTRFDYALPCFLTVVTMPF
Mb3301|M.bovis_AF2122/97            KLAHIKLAWRTGNFVIYAITIVCVVFLNLLEGVAIGLVVAIVFLLVRVVR
Rv3273|M.tuberculosis_H37Rv         KLAHIKLAWRTGNFVIYAITIVCVVFLNLLEGVAIGLVVAIVFLLVRVVR
MMAR_1266|M.marinum_M               QLAHIQIAWRTGNFAIYVITILGVIFLNLLEGVVIGLGVAIAFLLIRVIR
MAV_0121|M.avium_104                KPAHIETALRNGDLAIYLVTVTSVIFLNLLHGVLIGLLLAVVVTGWRVVR
MUL_5080|M.ulcerans_Agy99           QPAHIETAVKTGDFAIYLVTIVAVVFLNLLHGVMIGLALAIAMTGWRVLR
                                           . . .  .:  :    :  *. :.   :.  :.  .    :  

Mflv_0346|M.gilvum_PYR-GCK          SYSIANGIG--------------VGFISWAVLRTAAGKGREISPLLWVVA
Mvan_0392|M.vanbaalenii_PYR-1       SYSIANGIG--------------VGFITWVVMRTAAGKVREVSPLLWVVA
MSMEG_0564|M.smegmatis_MC2_155      SYSIANGIG--------------VGFVAWVVLRSAAGKFREISPLLWVVA
TH_1201|M.thermoresistible__bu      SYSIANGIG--------------IGFISWVVMRSAVGRAREVSPLLWVVA
MAB_3353c|M.abscessus_ATCC_199      TYSIANGIG--------------VGFISWVVLALARGRFRSVHPLLYVVA
Mb3301|M.bovis_AF2122/97            APVEVKPVGGEQSKRWRVDIDGTLSFLLLPRLTTVLSKLPEGSEVTLNLN
Rv3273|M.tuberculosis_H37Rv         APVEVKPVGGEQSKRWRVDIDGTLSFLLLPRLTTVLSKLPEGSEVTLNLN
MMAR_1266|M.marinum_M               APIEARLVS-EEAKRWRVDIDGTLSFLLLPRLTNVLSELPEGSDITLNLN
MAV_0121|M.avium_104                ARIEAEPVG----DGWHVVIEGACTFLALPRLTGVLASIPERTSVTVHLL
MUL_5080|M.ulcerans_Agy99           AKVEAHQID----GEWRVVVEGACTFLSLPRLTRVLASVPDSATVTLHIA
                                    :   .. :.                *:    :  . .   .   :   : 

Mflv_0346|M.gilvum_PYR-GCK          AGFAVYFARTPLESLLGV--------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       AGFAVYFARTPLESLIGV--------------------------------
MSMEG_0564|M.smegmatis_MC2_155      LGFVLYFARGWIESFIGM--------------------------------
TH_1201|M.thermoresistible__bu      AGFLLYFARGWIEALAGV--------------------------------
MAB_3353c|M.abscessus_ATCC_199      MLFVIYFAKGPIEDLLAHGA------------------------------
Mb3301|M.bovis_AF2122/97            ADYIDDSVSEAISDWRRAHETRGGVVAIVETSPAKLHHAHARPPKRHFAS
Rv3273|M.tuberculosis_H37Rv         ADYIDDSVSEAISDWRRAHETRGGVVAIVETSPAKLHHAHARPPKRHFAS
MMAR_1266|M.marinum_M               ADYIDHSVSEAISDWKTAHEATGGEVTIIETSPANLVSAHTSPPKRHFMS
MAV_0121|M.avium_104                TNYLDHAAHQAIGDWQRRHCATGGTVEVRDTTEPAARRRNSH--------
MUL_5080|M.ulcerans_Agy99           VNYLDHAAHQAITDWQRRHHATGGKVRIDGALR-RGHFANDG--------
                                      :    .   :                                      

Mflv_0346|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0564|M.smegmatis_MC2_155      --------------------------------------------------
TH_1201|M.thermoresistible__bu      --------------------------------------------------
MAB_3353c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3301|M.bovis_AF2122/97            DPIGLVPWRSAR-GKDRGSASVLDRIDEYHRNGAAVLHPHIAGLTDSQDP
Rv3273|M.tuberculosis_H37Rv         DPIGLVPWRSAR-GKDRGSASVLDRIDEYHRNGAAVLHPHIAGLTDSQDP
MMAR_1266|M.marinum_M               RAL-REPWTSRRDSHPDAEPSIRHGVEEYHRNGIGTLHHHVRELMDPANP
MAV_0121|M.avium_104                ----------------------LSLVEQVSSPGGA---------------
MUL_5080|M.ulcerans_Agy99           ----------------------TQLVHDERSEAAA---------------
                                                                                      

Mflv_0346|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0564|M.smegmatis_MC2_155      --------------------------------------------------
TH_1201|M.thermoresistible__bu      --------------------------------------------------
MAB_3353c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3301|M.bovis_AF2122/97            YELFLTCADSRILPNVITASGPGDLYTVRNLGNLVPTDPDDRSVDAALDF
Rv3273|M.tuberculosis_H37Rv         YELFLTCADSRILPNVITASGPGDLYTVRNLGNLVPTDPDDRSVDAALDF
MMAR_1266|M.marinum_M               DTVFLTCADSRILPDVITASKPGDLYIVRNVGNLVPIDPTERSVDAALDF
MAV_0121|M.avium_104                --------------------------------------------------
MUL_5080|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_0346|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0564|M.smegmatis_MC2_155      --------------------------------------------------
TH_1201|M.thermoresistible__bu      --------------------------------------------------
MAB_3353c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3301|M.bovis_AF2122/97            AVNQLGVSSVVVCGHSSCAAMTALLEDDPANTTTPMMRWLENAHDSLVVF
Rv3273|M.tuberculosis_H37Rv         AVNQLGVSSVVVCGHSSCAAMTALLEDDPANTTTPMMRWLENAHDSLVVF
MMAR_1266|M.marinum_M               AVNQLGVSSVVVCGHSSCRSMQALLDNGASDVDRPMNHWLEHAHDSLAAF
MAV_0121|M.avium_104                --------------------------------------------------
MUL_5080|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_0346|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0564|M.smegmatis_MC2_155      --------------------------------------------------
TH_1201|M.thermoresistible__bu      --------------------------------------------------
MAB_3353c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3301|M.bovis_AF2122/97            RNHHPARRSAESAGYPEADQLSIVNVAVQVERLTRHPILATAVAAADLQV
Rv3273|M.tuberculosis_H37Rv         RNHHPARRSAESAGYPEADQLSIVNVAVQVERLTRHPILATAVAAADLQV
MMAR_1266|M.marinum_M               RDGHPARASAASVGFGELDQLAVVNVAVQLERLAHNQVLAPAIASGAIQI
MAV_0121|M.avium_104                --------------------------------------------------
MUL_5080|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_0346|M.gilvum_PYR-GCK          -------------------------------------
Mvan_0392|M.vanbaalenii_PYR-1       -------------------------------------
MSMEG_0564|M.smegmatis_MC2_155      -------------------------------------
TH_1201|M.thermoresistible__bu      -------------------------------------
MAB_3353c|M.abscessus_ATCC_199      -------------------------------------
Mb3301|M.bovis_AF2122/97            IGIFFDISTARVYEVGPNGIICPDEPADRPVDHESAQ
Rv3273|M.tuberculosis_H37Rv         IGIFFDISTARVYEVGPNGIICPDEPADRPVDHESAQ
MMAR_1266|M.marinum_M               VGMFFDFSTVHVHEVDQLGIVASNQPVGKP-------
MAV_0121|M.avium_104                -------------------------------------
MUL_5080|M.ulcerans_Agy99           -------------------------------------