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GGEVVDPGIVIGIDGSPGSDAALKWAVQEATMRNVALTVVHAAAYVPDAAPKVEWFGDPAPDELLQQLDT RAQQVLADAVQIVKDATGDHRLRIIHELSSQSPVPALVELSRKADLVVVGSRGQGLVKRMLLGSVSTGLV HHAHCPVAVVPSEVPPPVEGPVVVGIDGSPASELATAIAFDEASWRGAELVALHAWTDAEVPAAANRDWT GTTRTSWSELQAAADETLAERLVGWRERYPDVVVRRVVVVNRATQHLIEHAESAQLVVVGSHGRGGFSGM LLGSVSTAVVHAVRAPVIVARQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4922 | - | - | 100% (304) | hypothetical protein MMAR_4922 |
| M. marinum M | MMAR_5410 | - | 1e-79 | 51.96% (306) | hypothetical protein MMAR_5410 |
| M. marinum M | MMAR_2993 | - | 5e-79 | 53.02% (298) | hypothetical protein MMAR_2993 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2028c | - | 1e-77 | 52.17% (299) | hypothetical protein Mb2028c |
| M. gilvum PYR-GCK | Mflv_4382 | - | 5e-76 | 52.00% (300) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2005c | - | 1e-77 | 52.17% (299) | hypothetical protein Rv2005c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2489 | - | 1e-49 | 41.44% (292) | hypothetical protein MAB_2489 |
| M. avium 104 | MAV_2507 | - | 6e-77 | 52.63% (304) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3936 | - | 6e-69 | 48.48% (297) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 1e-77 | 49.68% (308) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_0483 | - | 1e-170 | 98.36% (304) | hypothetical protein MUL_0483 |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 2e-75 | 50.50% (301) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2028c|M.bovis_AF2122/97 --MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNAD-
Rv2005c|M.tuberculosis_H37Rv --MSKPRKQHGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNAD-
MAV_2507|M.avium_104 --MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVNA--
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
Mflv_4382|M.gilvum_PYR-GCK --MSTQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPGA-
Mvan_1963|M.vanbaalenii_PYR-1 --MSTQPAPVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPSA-
MMAR_4922|M.marinum_M --MGGEVVDPGIVIGIDGSPGSDAALKWAVQEATMRNVALTVVHAAAYVP
MUL_0483|M.ulcerans_Agy99 --MGGEVVDPGIVIGIDGSPGSDAALKWAVQEATMRNVALTVVHAAAYVP
MSMEG_3936|M.smegmatis_MC2_155 MSVADSDLPHGIVVGVDGSSWSRAAVRWAMAEATLRGVDLTIAHVVT--P
MAB_2489|M.abscessus_ATCC_1997 --MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHSS
: :::.:*** : * *. .* * : **:.:
Mb2028c|M.bovis_AF2122/97 ----VATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLS---
Rv2005c|M.tuberculosis_H37Rv ----VATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLS---
MAV_2507|M.avium_104 ----ATVWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLA---
TH_2494|M.thermoresistible__bu IGA-PLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGP
Mflv_4382|M.gilvum_PYR-GCK --A-VQSWIQVPLPASFYEDEKAEATRVLADARAVVDAATQAHPLPA---
Mvan_1963|M.vanbaalenii_PYR-1 --A-TQSWIQVPLPAAFFEDEKLEAERILADARALVTAATEGGEALT---
MMAR_4922|M.marinum_M DAAPKVEWFGDPAPDELLQQLDTRAQQVLADAVQIVK-DATGDHRLR---
MUL_0483|M.ulcerans_Agy99 YAAPKVEWFGDPAPDELLQQLDTRAQQVLADAVQIVK-DATGDHRLR---
MSMEG_3936|M.smegmatis_MC2_155 LSASTLLWPGGRIPEEVLEVQDNDARTAIADAIKIVQEDVTGTSRPQ---
MAB_2489|M.abscessus_ATCC_1997 ----LGQGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPNVEVST---
. . . : :: .
Mb2028c|M.bovis_AF2122/97 -------VKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVS
Rv2005c|M.tuberculosis_H37Rv -------VKSELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVS
MAV_2507|M.avium_104 -------ITTELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLGSVS
TH_2494|M.thermoresistible__bu AGDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVS
Mflv_4382|M.gilvum_PYR-GCK -------VTEKVLSGQPVPTLADLSRDADMIVVGSRGMGKWERRVLGSVS
Mvan_1963|M.vanbaalenii_PYR-1 -------VDEVVLSGQPVAALVDLAKDAEMLVMGSRGLGKWERRLLGSVS
MMAR_4922|M.marinum_M -------IIHELSSQSPVPALVELSRKADLVVVGSRGQGLVKRMLLGSVS
MUL_0483|M.ulcerans_Agy99 -------IIHELSSQSPVPALVELSRKADLVVVGSRGQGLVKRMLLGWVS
MSMEG_3936|M.smegmatis_MC2_155 -------VRSEMLYGGVVPSLTGFSRSAELIVVGPRGRNEQHRRLLGSVA
MAB_2489|M.abscessus_ATCC_1997 ----------VKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSVS
.. :. :..* : .:*. * . : * *:
Mb2028c|M.bovis_AF2122/97 SSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDEA
Rv2005c|M.tuberculosis_H37Rv SSLVRRAGCPVAVIHSDDAVIPDPQHAPVLVGIDGSPVSELATAVAFDEA
MAV_2507|M.avium_104 SGLVRRARCPVAVIHDEDPMMPYPQRAPVLVGIDGSPASELATAIAFDEA
TH_2494|M.thermoresistible__bu SGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEA
Mflv_4382|M.gilvum_PYR-GCK SGLVHHARCPVAVIYDEDPLIPHPAQAPVVVGIDGSPASERATAIAFDEA
Mvan_1963|M.vanbaalenii_PYR-1 SGVVHHAHCPVAVIHDVDPLIPHPAQAPVVVGVDGSPASEHATAIAFDEA
MMAR_4922|M.marinum_M TGLVHHAHCPVAVVPSEVPPP-VEG--PVVVGIDGSPASELATAIAFDEA
MUL_0483|M.ulcerans_Agy99 TGLVHHAHCPVAVVPSEVPPP-VEG--PVVVGIDGSPASELATAIAFDEA
MSMEG_3936|M.smegmatis_MC2_155 SGLLHHARCPVAIVHATGAAR-VSGRSPVLLGTDGSPASEFATEIAFREA
MAB_2489|M.abscessus_ATCC_1997 VSLTAKGHSPVVVVRES----PVPGGGPVVVGIDDSESSDGAAAWAFEEA
.: :. .**.:: **::* *.* :: *: ** **
Mb2028c|M.bovis_AF2122/97 SRRGVELIAVHAWSDVEV--------VELPGLDFSAVQQEAELSLAERLA
Rv2005c|M.tuberculosis_H37Rv SRRGVELIAVHAWSDVEV--------VELPGLDFSAVQQEAELSLAERLA
MAV_2507|M.avium_104 LRRGVDLNAVHAWSDTQV--------FGLPGMDWPAVRSQAERSLAERLA
TH_2494|M.thermoresistible__bu SFRGVDLIALHAWSDADI--------ADIPTLELSAVQQSAERVLSERLA
Mflv_4382|M.gilvum_PYR-GCK CRRGVDLVAVHTWSDAG---------YELPGVEWTEVQPEEEMLLSERLA
Mvan_1963|M.vanbaalenii_PYR-1 SFRGVDLVAVHTWSDAG---------YELPGTGWAEIQPEEDMLLAERLA
MMAR_4922|M.marinum_M SWRGAELVALHAWTDAEVPAAANRDWTGTTRTSWSELQAAADETLAERLV
MUL_0483|M.ulcerans_Agy99 SWRGAELVALHAWTDAEIPAAANRDWTGTTRTSWSELQAATDETLAERLV
MSMEG_3936|M.smegmatis_MC2_155 ALRGVDVVALHVLVDADM--------SGLFAAEWSALQAVVQKPIAERLG
MAB_2489|M.abscessus_ATCC_1997 AMRETELVAVHVWNNIPPG--YVYAYTAWSAMDSAGEQQRQEQLLAERLA
* .:: *:*. : . : : ::***
Mb2028c|M.bovis_AF2122/97 GWQERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLG
Rv2005c|M.tuberculosis_H37Rv GWQERYPDVPVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLG
MAV_2507|M.avium_104 GWQERYPDVTVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLG
TH_2494|M.thermoresistible__bu GFRERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLG
Mflv_4382|M.gilvum_PYR-GCK GWHERYPDVTVHRVVRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLLG
Mvan_1963|M.vanbaalenii_PYR-1 GWQERYPDVTVHRVVCRDQPARRLLEEAAKGQLLVVGSHGRGGFGGMLLG
MMAR_4922|M.marinum_M GWRERYPDVVVRRVVVVNRATQHLIEHAESAQLVVVGSHGRGGFSGMLLG
MUL_0483|M.ulcerans_Agy99 GWRERYPDVVVRRVVVVNRVTQHLIEHAESAQLVVVGSHGRGGFSGMLLG
MSMEG_3936|M.smegmatis_MC2_155 AWEERYPETSVNLEIEFDRPADALIAASEGAQLVVLGSRGRGGFTGMLLG
MAB_2489|M.abscessus_ATCC_1997 GWQEKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLG
.:.*:**:. * : .. : *: : .** * **:***.: * :**
Mb2028c|M.bovis_AF2122/97 SVSNAVLHAARVPVIVARQS
Rv2005c|M.tuberculosis_H37Rv SVSNAVLHAARVPVIVARQS
MAV_2507|M.avium_104 SVSNAVVHSVRMPVIVARPS
TH_2494|M.thermoresistible__bu SVSRAVVNAVTTPVIVAR--
Mflv_4382|M.gilvum_PYR-GCK SVGSQIVQSSRTPVIVARTA
Mvan_1963|M.vanbaalenii_PYR-1 SVGSQVVQSARGPVIVARR-
MMAR_4922|M.marinum_M SVSTAVVHAVRAPVIVARQG
MUL_0483|M.ulcerans_Agy99 SVSTAVVHAVRAPVIVARQG
MSMEG_3936|M.smegmatis_MC2_155 SVSSAVAQEVRVPIIVARPR
MAB_2489|M.abscessus_ATCC_1997 STSHALIHKASCPVLVAPRT
*.. : : *::**