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AEVEAAMSRPGAHTASSAAVLDATRAVATLGGFKAVHFKSVAKQAGVTVGSVYDHFTSKTHLLVTLLARE FVRLDEERDWSTCAASPIRRVESLTRRLHDEWQQNVKLTEAVVRAFVTAGTDEALAAQHAADLIESMLAR ALSGGTEGIHERQIAGLIADIWLANLMAFVGGRATAEQTRECIDGAMRLVLDVGGRQRSLAIPTVSLRY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4839 | - | - | 100% (210) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5069 | - | 3e-31 | 40.46% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4304 | - | 1e-05 | 38.67% (75) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 2e-32 | 41.62% (173) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_4581 | - | 4e-43 | 46.88% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 2e-32 | 41.62% (173) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0579c | - | 4e-28 | 36.93% (176) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3803 | - | 2e-44 | 54.12% (170) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 2e-32 | 41.62% (173) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 1e-32 | 41.48% (176) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_4145 | - | 2e-31 | 40.46% (173) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0321 | - | 2e-42 | 46.88% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6042|M.smegmatis_MC2_155 ------------------------------------------MTNVAVLS
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
MUL_4145|M.ulcerans_Agy99 ---------------------------------------------MAVLA
MAB_0579c|M.abscessus_ATCC_199 -------------MATPRTSSASEAAQSGDGDTDATS----QPAAVSALS
Mflv_4581|M.gilvum_PYR-GCK -------------MTFPQARSHGKTLPSEANS-----------VATEKRA
Mvan_0321|M.vanbaalenii_PYR-1 -------------MTFPQARSRGTTLPSEANS-----------VATEKRA
MMAR_4839|M.marinum_M -------------------------------------------MAEVEAA
MAV_3803|M.avium_104 -------------------------------------------MSAPTAA
:
MSMEG_6042|M.smegmatis_MC2_155 ESE------LGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVA
TH_1745|M.thermoresistible__bu DSE------LGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVA
Mb3605|M.bovis_AF2122/97 ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
Rv3574|M.tuberculosis_H37Rv ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
MUL_4145|M.ulcerans_Agy99 ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
MAB_0579c|M.abscessus_ATCC_199 DDD------LGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVA
Mflv_4581|M.gilvum_PYR-GCK ANA------SRSRASARRRETILDAALTVAAAGGYEAVQMRTVAERVGIA
Mvan_0321|M.vanbaalenii_PYR-1 ANA------SRSRASARRRETILDAALAVAAAGGYEAVQMRTVAERVGIA
MMAR_4839|M.marinum_M MS-------RPGAHTASS-AAVLDATRAVATLGGFKAVHFKSVAKQAGVT
MAV_3803|M.avium_104 PRDRVRHPRRPADSVLVRREAILDAAWAVASAQGFDGVQMRAVAAQAGIA
. :***: ::*: *:..*::::** :..::
MSMEG_6042|M.smegmatis_MC2_155 VGTLYRYFPSKVHLLVSALGREFERIDAKTDRAALAGGTPYQRLNFMVGK
TH_1745|M.thermoresistible__bu VGTLYRYFPSKVHLLVSALGREFERIDAKTDRSTLVGDTPYERLNFMVSR
Mb3605|M.bovis_AF2122/97 VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGK
Rv3574|M.tuberculosis_H37Rv VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGK
MUL_4145|M.ulcerans_Agy99 VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAMTGGTPFQRLNFMVGK
MAB_0579c|M.abscessus_ATCC_199 VGTLYRYFPSKVHLLVSALEREFEQIDAKSDRNAVSGGTPYERLHAAITR
Mflv_4581|M.gilvum_PYR-GCK VGTLYRYFPAKTHLLVAALTREFRRLDSAGDWASGEG-PPLERLERLTAH
Mvan_0321|M.vanbaalenii_PYR-1 VGTLYRYFPAKTHLLVAALTREFRRLDSAGDWAGGEG-TPLERLERLTAH
MMAR_4839|M.marinum_M VGSVYDHFTSKTHLLVTLLAREFVRLDEERDWSTCAA-SPIRRVESLTRR
MAV_3803|M.avium_104 ASSLYRHFRSKSHLLVTVLAREFERLDTEFDCTTGEL-APQARLGRLTTH
..::* :* :* ****: * *** ::* * .* *: :
MSMEG_6042|M.smegmatis_MC2_155 LNRAMQRNPLLTEAMTRAFVFADASAAGEVDHVGKLMDSMFARAMS-DGE
TH_1745|M.thermoresistible__bu LNRAMQRNPLLTEAMTRAFVFADASAAGEVDHVGRLMDSMFARAMA-DGE
Mb3605|M.bovis_AF2122/97 LNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMA-NGE
Rv3574|M.tuberculosis_H37Rv LNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMA-NGE
MUL_4145|M.ulcerans_Agy99 LNRAMQRNPLLTEAMTRAYVFADASAATEVDQVEKLIDSMFARAMA-DGE
MAB_0579c|M.abscessus_ATCC_199 LNRNMQRNPLLTEAMTRALVFADASAAGEVDHVGRLMDGIFARAMAGEDD
Mflv_4581|M.gilvum_PYR-GCK LHDRWQRDPRLTTAMTRAFAVADTRAAAELDRAADEIQILLARTLR-GGE
Mvan_0321|M.vanbaalenii_PYR-1 LHDRWQRDPWLTTAMTRAFAVADTRAAAELDRAADEIQILLARTLR-GGE
MMAR_4839|M.marinum_M LHDEWQQNVKLTEAVVRAFVTAGTDEALAAQHAADLIESMLARALS-GGT
MAV_3803|M.avium_104 LHMAWQANPHLTEAMVRAFVVADSEAAGAIEHAVAVIEDMLARALG-GPT
*: * : ** *:.** . *.: * ::. :: ::**::
MSMEG_6042|M.smegmatis_MC2_155 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
TH_1745|M.thermoresistible__bu PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLELAV--------R
Mb3605|M.bovis_AF2122/97 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
Rv3574|M.tuberculosis_H37Rv PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
MUL_4145|M.ulcerans_Agy99 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
MAB_0579c|M.abscessus_ATCC_199 PTDAQFHIARVISDVWTSNMIAWLTRRASATDVSHRLDRTV--------R
Mflv_4581|M.gilvum_PYR-GCK PTPTDLHVAGVISDIWLANLVAFSGHRATAADTRERIDRAT--------R
Mvan_0321|M.vanbaalenii_PYR-1 PTPADLHVAGVISDIWLANLVAFSGDRATAADTRDRIDRAT--------R
MMAR_4839|M.marinum_M EGIHERQIAGLIADIWLANLMAFVGGRATAEQTRECIDGAMRLVLDVGGR
MAV_3803|M.avium_104 PSAHDRDVASLIADVWLANLIAVIGGRIDADLARERIDRTT--------R
: .:* :*:*:* :*::* * * . . :: : *
MSMEG_6042|M.smegmatis_MC2_155 LLIGTEEQPKI--
TH_1745|M.thermoresistible__bu LLVGDGKNPKV--
Mb3605|M.bovis_AF2122/97 LLIGDQDSA----
Rv3574|M.tuberculosis_H37Rv LLIGDQDSA----
MUL_4145|M.ulcerans_Agy99 LLIGDQEATA---
MAB_0579c|M.abscessus_ATCC_199 LLLGIT-------
Mflv_4581|M.gilvum_PYR-GCK RVVTSAARPTANR
Mvan_0321|M.vanbaalenii_PYR-1 RVVTNAARPTANR
MMAR_4839|M.marinum_M QRSLAIPTVSLRY
MAV_3803|M.avium_104 QLVHGTDTTT---