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VAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGR EFSRIDAKTDRSAMTGGTPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAATEVDQVEKLIDSMF ARAMADGEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQEATA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4145 | - | - | 100% (200) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4956 | - | 1e-14 | 29.79% (188) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4875 | - | 4e-08 | 30.53% (95) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 1e-103 | 96.46% (198) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1459 | - | 6e-95 | 90.82% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 1e-103 | 96.46% (198) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00815 | - | 7e-07 | 29.08% (141) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 3e-79 | 75.38% (195) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5069 | - | 1e-108 | 100.00% (200) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0584 | - | 1e-103 | 97.44% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 1e-98 | 91.88% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 2e-95 | 89.23% (195) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. vanbaalenii PYR-1 | Mvan_5312 | - | 6e-95 | 91.33% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1459|M.gilvum_PYR-GCK MSGSS------ESAT------------AGSDS------RPRQVMNVAVLA
Mvan_5312|M.vanbaalenii_PYR-1 MSGTS------EFAADKSQTSARATSGAGSES------RPRQVMNVAVLA
MSMEG_6042|M.smegmatis_MC2_155 ------------------------------------------MTNVAVLS
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
MUL_4145|M.ulcerans_Agy99 ---------------------------------------------MAVLA
MMAR_5069|M.marinum_M ---------------------------------------------MAVLA
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
MAV_0584|M.avium_104 ---------------------------------------------MAVLA
MAB_0579c|M.abscessus_ATCC_199 -----------------MATPRTSSASEAAQSGDGDTDATSQPAAVSALS
MLBr_00815|M.leprae_Br4923 ----------------------MNNLAKAAQRRTVRPIDRGRLSDDIATP
. .
Mflv_1459|M.gilvum_PYR-GCK ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
Mvan_5312|M.vanbaalenii_PYR-1 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MSMEG_6042|M.smegmatis_MC2_155 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
TH_1745|M.thermoresistible__bu DSELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MUL_4145|M.ulcerans_Agy99 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MMAR_5069|M.marinum_M ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Mb3605|M.bovis_AF2122/97 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Rv3574|M.tuberculosis_H37Rv ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MAV_0584|M.avium_104 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MAB_0579c|M.abscessus_ATCC_199 DDDLGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVAVGTLYR
MLBr_00815|M.leprae_Br4923 NQRSNRLSRDKRRGQLLIVASDVFVDHGYHAAGMDEIADRAGVSKPVLYQ
:. . :: :** ::* .: : . **.*. * :*:**.*: .**:
Mflv_1459|M.gilvum_PYR-GCK YFPSKVHLLVSALGREFERIDAKTDRAALAAGATAYQRLNIMVGKLNRAM
Mvan_5312|M.vanbaalenii_PYR-1 YFPSKVHLLVSALGREFERIDAKTDRSAFPAGATAYQRLNIMVGKLNRAM
MSMEG_6042|M.smegmatis_MC2_155 YFPSKVHLLVSALGREFERIDAKTDRAALAGG-TPYQRLNFMVGKLNRAM
TH_1745|M.thermoresistible__bu YFPSKVHLLVSALGREFERIDAKTDRSTLVGD-TPYERLNFMVSRLNRAM
MUL_4145|M.ulcerans_Agy99 YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
MMAR_5069|M.marinum_M YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
Mb3605|M.bovis_AF2122/97 YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
Rv3574|M.tuberculosis_H37Rv YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
MAV_0584|M.avium_104 YFPSKVHLLVSALGREFSRIDAKTDRAALTGG-TPFQRLNFMVGKLNRAM
MAB_0579c|M.abscessus_ATCC_199 YFPSKVHLLVSALEREFEQIDAKSDRNAVSGG-TPYERLHAAITRLNRNM
MLBr_00815|M.leprae_Br4923 HFSSKLELYLAVLERHMNNLVSSVQQALRTTT-NNRQRLHAAVQAFFDFI
:*.**:.* ::.* *.:..: :. :: . :**: : : :
Mflv_1459|M.gilvum_PYR-GCK QRNPLLTEAMTRAFVFADASAAGEVDHVGK-LMDSMFARAMS-DGEPTED
Mvan_5312|M.vanbaalenii_PYR-1 QRNPLLTEAMTRAFVFADASAAGEVDHVGK-LMDSMFARAMS-DGEPTED
MSMEG_6042|M.smegmatis_MC2_155 QRNPLLTEAMTRAFVFADASAAGEVDHVGK-LMDSMFARAMS-DGEPTED
TH_1745|M.thermoresistible__bu QRNPLLTEAMTRAFVFADASAAGEVDHVGR-LMDSMFARAMA-DGEPTED
MUL_4145|M.ulcerans_Agy99 QRNPLLTEAMTRAYVFADASAATEVDQVEK-LIDSMFARAMA-DGEPTED
MMAR_5069|M.marinum_M QRNPLLTEAMTRAYVFADASAATEVDQVEK-LIDSMFARAMA-DGEPTED
Mb3605|M.bovis_AF2122/97 QRNPLLTEAMTRAYVFADASAASEVDQVEK-LIDSMFARAMA-NGEPTED
Rv3574|M.tuberculosis_H37Rv QRNPLLTEAMTRAYVFADASAASEVDQVEK-LIDSMFARAMA-NGEPTED
MAV_0584|M.avium_104 QRNPLLTEAMTRAYVFADASAASEVDQVEK-LIDSMFARAMA-DGEPTED
MAB_0579c|M.abscessus_ATCC_199 QRNPLLTEAMTRALVFADASAAGEVDHVGR-LMDGIFARAMAGEDDPTDA
MLBr_00815|M.leprae_Br4923 EHDGQGYRLIFENDNITEPRVAAQVRVATESCIDAVFALISADSRLDPHR
::: . : . :::. .* :* . . :*.:** : . ..
Mflv_1459|M.gilvum_PYR-GCK QYHIARVISDVWLSNLLAWLTRRASATDVAKRLDLAVRLLIGDGDQPKI-
Mvan_5312|M.vanbaalenii_PYR-1 QYHIARVISDVWLSNLLAWLTRRASATDVAKRLDLAVRLLIGDGDQPKI-
MSMEG_6042|M.smegmatis_MC2_155 QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGTEEQPKI-
TH_1745|M.thermoresistible__bu QYHIARVISDVWLSNLLAWLTRRASATDVSKRLELAVRLLVGDGKNPKV-
MUL_4145|M.ulcerans_Agy99 QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQEATA--
MMAR_5069|M.marinum_M QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQEATA--
Mb3605|M.bovis_AF2122/97 QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA---
Rv3574|M.tuberculosis_H37Rv QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA---
MAV_0584|M.avium_104 QYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLLGEHG-----
MAB_0579c|M.abscessus_ATCC_199 QFHIARVISDVWTSNMIAWLTRRASATDVSHRLDRTVRLLLGIT------
MLBr_00815|M.leprae_Br4923 ARMVAVGLVGISVDCARYWLDTNR-PISKSDAVEGTVQFAWGGLSHVPLT
:* : .: . ** . . . :. :: :*:: *
Mflv_1459|M.gilvum_PYR-GCK --
Mvan_5312|M.vanbaalenii_PYR-1 --
MSMEG_6042|M.smegmatis_MC2_155 --
TH_1745|M.thermoresistible__bu --
MUL_4145|M.ulcerans_Agy99 --
MMAR_5069|M.marinum_M --
Mb3605|M.bovis_AF2122/97 --
Rv3574|M.tuberculosis_H37Rv --
MAV_0584|M.avium_104 --
MAB_0579c|M.abscessus_ATCC_199 --
MLBr_00815|M.leprae_Br4923 RL