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M. marinum M MMAR_4602 (-)

annotation: PE-PGRS family protein
coordinates: 5639613 - 5643368
length: 1251

LSYVTAAPEALAAAAGDLTGIGEALRAATAAAAPSTTSLVAAAGDEVSTAIATLFSEHAQSYQALSAQMA
AFHDRFMNALAGASGSYASAEAANVTPLQTIEQDLLGAVNAPTQVLFGRGLIGDGANGTAPGQAGGAGGL
LIGNGGNGAPGAVGQAGGAGGAAGLLGNGGTGGAGGAGANGGAGGSAGLWGAGGAGGAGGAGATPGGAGG
AGGTGGANGLVGGGNGGAGGAGGVGGTGATGTTGGVGGDGGAGGAGGVGGVDRALIGWSGGAGGVGGSGG
AGGLGGTGSAGAGLGATGGDGGAGGVGGQAGAGGAGGAVTGSINPLGNAGAHGANGTGGVGGTGGVGGAG
GTGIAGTGDLVSPTAGYQGGQGGMGGKGGDGGAGIGGVGGGAGGEGGVGGAGGTGGQGGANTGATGGMGA
DGGKGGTGGAAGAGGMGTDGGAAGANGTGGVGGTGGDGGAGGTGIAGTDDQVSPTAGHQGGQGGMGGTGG
DGGAGIGGVGGGAGGKGGVGGAGGTGGQGGGPGGTGGIASALDSGAGAQGGGIPSTTGVPGADGGKGGTG
GTAGAAGVGVDGGAAGSIGAGGVGGTGGNGGAGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGG
VGGGAGGHGGIGGSGGAGSNGGNNTGSTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSIGTGGVGGTGGN
GGAGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGGVGGGAGGHGGVGGSGGAGSNGGNNTGSTG
GVGADGGKGGTGGTAGAAGVGVDGGAAGSIGTGGVGGQGGDGGSGGTGALGADGTNPTGGGRGGQGGQGG
QGGDGGSGIGGVGGGAGGHGGVGGSGGTGGTGGSNTASTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSI
GTGGVGGTGGEGGSGGTGVAGASGITPAVGGPGGQGGAGGTGGDGGAGIDGVGGGAGGQGGQGGAGGNGG
MGGTYTGTGPGSSASGGTGGAGGAGGDGGAPGAGSTTGGVGGNGGKGGNGGFGAGNSSGSSAGFGFGGGG
GGGGAGGHGGNGGGGGASGGQGGAGGDGGLGGTAVSPTTGSAAGGGFGGGGGGGGNATGAAGGTGGGGGG
GGAGAAAAVAAAGGGGGGGGAAGGPGGTAGNGGVGGNAFGGGSSGTGGTAGAGAPGGVGGGGGGGAVAQS
SFANNGGPGRDGADGGDGGAGGFIIGTYGGNGGGAAGAGGGGGAAFNVVATAQGGQGQSG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4602--100% (1251)PE-PGRS family protein
M. marinum MMMAR_5294-0.048.47% (1471) PE-PGRS family protein
M. marinum MMMAR_2033-0.051.04% (1348) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3538PE_PGRS540.049.09% (1477) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-0.047.03% (859) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS540.046.73% (1558) PE-PGRS family protein
M. leprae Br4923MLBr_01183-3e-1341.30% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-5333.03% (545) hypothetical protein MAB_4284c
M. avium 104MAV_4827-2e-2644.21% (190) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-17342.70% (1075) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-4437.07% (348) PUTATIVE -
M. ulcerans Agy99MUL_4367-0.050.09% (1134) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-0.045.05% (868) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            -----------------------------------------MSFVLIAPE
Rv3508|M.tuberculosis_H37Rv         -----------------------------------------MSFVLIAPE
MUL_4367|M.ulcerans_Agy99           -----------------------------------------MSFVSVGPG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               ----------------------------------------MLSYVTAAPE
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------MSIIDFILNLFR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------MNIVLGVSMAPS
                                                                                      

Mb3538|M.bovis_AF2122/97            FVTAAAGDLTNLGSSISAANASAASATTQVLAAG----------------
Rv3508|M.tuberculosis_H37Rv         FVTAAAGDLTNLGSSISAANASAASATTQVLAAG----------------
MUL_4367|M.ulcerans_Agy99           LLEAAARDLAGLGAGLREANLAAAGATVGVLPAA----------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------MMFLAPPGGPGPISAAIQLTSTG----------------
MMAR_4602|M.marinum_M               ALAAAAGDLTGIGEALRAATAAAAPSTTSLVAAA----------------
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      DPVEAASYVADPEAALANAGLSAVSAAQVGAVMP----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SIQMVVLEGEYADGATVEEDAIDVTGADDAATAS----------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS
Rv3508|M.tuberculosis_H37Rv         ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS
MUL_4367|M.ulcerans_Agy99           ----GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ
Mflv_5091|M.gilvum_PYR-GCK          ------------MVTFGGGA------TPTPTSLGAAAVDLSGTSCG----
Mvan_1264|M.vanbaalenii_PYR-1       ----SEATEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG----
MMAR_4602|M.marinum_M               ----GDEVSTAIATLFSEHAQSYQALSAQMAAFHDRFMNALAGASGSYAS
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------APDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDAL
                                                                                      

Mb3538|M.bovis_AF2122/97            AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT
Rv3508|M.tuberculosis_H37Rv         AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT
MUL_4367|M.ulcerans_Agy99           AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------LICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------LICNGQD---
MMAR_4602|M.marinum_M               AEAANVTPLQ---------TIEQDLLGAVNAPTQVLFGRGLIGDGAN-GT
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------PSILSPSLLSPRDNDFL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AARR---------------------------IDNVMLVSAFLAAAALAQN
                                                                                      

Mb3538|M.bovis_AF2122/97            TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
Rv3508|M.tuberculosis_H37Rv         TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG
MUL_4367|M.ulcerans_Agy99           GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG--
Mflv_5091|M.gilvum_PYR-GCK          ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG--
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG--
MMAR_4602|M.marinum_M               APGQAGGAGGLLIGNGGNGA-PGAVGQAGGAGGAAGLLGNGGTGGAGG--
MSMEG_0868|M.smegmatis_MC2_155      ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGW--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRD--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG----
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGG
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGG
MUL_4367|M.ulcerans_Agy99           ---------------VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAG
Mflv_5091|M.gilvum_PYR-GCK          ------------------------LGGGNGGNGGNAGAFALFGN------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------LGSGDGGNGGDAGLFSLFGR------
MMAR_4602|M.marinum_M               -------------------------AGANGGAGGSAG-LWGAGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------AGLDGGNGGSGGLLMGIGGAGGAGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------TTAIGDGAVAVGGSNSG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------DAAGQLSAMVAGLEKLESLPG
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGGDGG
Rv3508|M.tuberculosis_H37Rv         AGGGTGGAGGRAELLFGAGGAGGAG---TDGGPGATGGTGGHGGVGGDGG
MUL_4367|M.ulcerans_Agy99           AGG-----------------------------------------SGGSGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               AG------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      VGADG---------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                G-------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            WLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLG
Rv3508|M.tuberculosis_H37Rv         WLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLG
MUL_4367|M.ulcerans_Agy99           WLWG----NAGQTAGAG-----------VGGAGGAGGAGDAGDQGVSGVA
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------GGNGGNGGVGVVG--------
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------GGNGGNGGVGIAG--------
MMAR_4602|M.marinum_M               -ATPGGAGGAGGTGGANG--------LVGGGNGGAGGAGGVGGTG----A
MSMEG_0868|M.smegmatis_MC2_155      -TSAHVDGGTGGTGGTG------------GGTGGTGGIGGTGGGLFGLLG
TH_3810|M.thermoresistible__bu      -----VD----GDGGSG------------GRTG-----------LFSKLS
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGQGGLGGAGGQGGTGGAGGD-----GVLGGVGGTGGKGGVGGVAGLGG
Rv3508|M.tuberculosis_H37Rv         AGGQGGLGGAGGQGGTGGAGGD-----GVLGGVGGTGGKGGVGGVAGLGG
MUL_4367|M.ulcerans_Agy99           PGEAGAVGFAGGAGGAGGAGGN-----GVGGGVNGAGGAGGAGGVGGGGG
Mflv_5091|M.gilvum_PYR-GCK          -----ATGAVGAPGVAGATGAT-----GVTSGVVGGNGEDAVG----YGA
Mvan_1264|M.vanbaalenii_PYR-1       -----ATGAVGAPGVAGATGAT-----GVTSNVTGGNGADAVG----YGA
MMAR_4602|M.marinum_M               TGTTGGVGGDGGAGGAGGVGGVDRALIGWSGGAGGVGGSGGAGGLGGTGS
MSMEG_0868|M.smegmatis_MC2_155      HSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGG
TH_3810|M.thermoresistible__bu      R------------GGDGGDGGLG---------------------------
MAB_4284c|M.abscessus_ATCC_199      -------PIASGQGSTAVNGDVR------DSNIINADHGSNVGVDQSQTR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------LLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAA
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGAAGQLFSAGGAAGAVGVGGTGGQGGAG--------------------
Rv3508|M.tuberculosis_H37Rv         AGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLTGGTG
MUL_4367|M.ulcerans_Agy99           AG--------------ASGVG-----------------------------
Mflv_5091|M.gilvum_PYR-GCK          TG------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TG------------------------------------------------
MMAR_4602|M.marinum_M               AG---------------AGLG-----------------------------
MSMEG_0868|M.smegmatis_MC2_155      QS------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VG------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AN------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------------------------------------GMGGSGADNASGIG
Rv3508|M.tuberculosis_H37Rv         FAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADNASGIG
MUL_4367|M.ulcerans_Agy99           ------------------------------------------------AG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               -----------------------------------------------ATG
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------------------------T
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------------------AP
                                                                                      

Mb3538|M.bovis_AF2122/97            ADGGAGGTGGNAGAGGAGGAAG----TGGTGGVVGAAGKAGIGGTGGQGG
Rv3508|M.tuberculosis_H37Rv         ADGGAGGTGGNAGAGGAGGAAG----TGGTGGVVGAAGKAGIGGTGGQGG
MUL_4367|M.ulcerans_Agy99           VAGGDGGTGGAGGAAGVGGAAG----TGGTG------GAAGVAGTGGDGG
Mflv_5091|M.gilvum_PYR-GCK          -AAGAAGAAGAAGAAGAVGSAG----AAGEAGETGTWGNAGLPGKAG--D
Mvan_1264|M.vanbaalenii_PYR-1       -AAGAAGAAGAAGKAGAVGSAG----TAGSAGAPGVWGNAGLPGAAG--A
MMAR_4602|M.marinum_M               GDGGAGGVGGQAGAGGAGGAVTGSINPLGNAGAHGANGTGGVGGTGGVGG
MSMEG_0868|M.smegmatis_MC2_155      AAGPGKGGGGGGGGGGAILIGAN----GGTVDGHAIGGNGGNGGNGSTTA
TH_3810|M.thermoresistible__bu      ------GNGGHGGGTGIISLLS-------------LAGNGGNGGNGYRTT
MAB_4284c|M.abscessus_ATCC_199      ---GDYTNVSGHGSADIDKSVT-------VVDDHSQRNTTNINDSFNTDR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEE
                                                                                      

Mb3538|M.bovis_AF2122/97            AGGAGSAGTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGT
Rv3508|M.tuberculosis_H37Rv         AGGAGSAGTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGT
MUL_4367|M.ulcerans_Agy99           DGGAGGAGSDASLAGQAG---FAGGSGGAGGVGGSAGAGGVNGSGGDGGA
Mflv_5091|M.gilvum_PYR-GCK          AGGAGAVG-AAGAAGTVG----TAGATGGTGTGANGGAGGVGGVGGTGAA
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGAIG-TAGVAGAAG----TAGATGGTGVGGNGGAGQAGGIGGTGAA
MMAR_4602|M.marinum_M               AGGTGIAGTGDLVSPTAG---YQGGQGGMGGKGGDGGAGIGGVGGGAGGE
MSMEG_0868|M.smegmatis_MC2_155      AGGNGGTGGTGRVIAEGT-----GSTAEGTATGGDGGHSTGTGIGGNGGI
TH_3810|M.thermoresistible__bu      DNN--------------------------ALDGGHGGN------GGNVGF
MAB_4284c|M.abscessus_ATCC_199      STNIGSGNTTNTEIGSHN----QANIGTSTSAGGSAAVGGNAGLAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DAESPTVVIEKLFLPEDS---EPRRRPVLLVGSGLAVVGISAVLALEIAL
                                                                                      

Mb3538|M.bovis_AF2122/97            GGAGGAGGAGGVGADNPTGIGGAGGTGG----------------------
Rv3508|M.tuberculosis_H37Rv         GGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGS
MUL_4367|M.ulcerans_Agy99           GAAGGAGGASAT-------VAGSGGVGG----------------------
Mflv_5091|M.gilvum_PYR-GCK          GAAGGAGGLGET--------GTTGGAGG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAAGQAGTAGET--------GVTGGVGG----------------------
MMAR_4602|M.marinum_M               GGVGGAGGTGGQGGANTGATGGMGADGG----------------------
MSMEG_0868|M.smegmatis_MC2_155      GSVYAYGNNGAVSG------TATGGRGG----------------------
TH_3810|M.thermoresistible__bu      FSLFNLG--------------GAGGWGG----------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAG-------NAGLAGN----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AIGIRTTGTVALQPTPNQHLIVPTEQAP----------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------AGGTGGTGGAAGAGGAGGAVGT
Rv3508|M.tuberculosis_H37Rv         GGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGT
MUL_4367|M.ulcerans_Agy99           -------------------------------DGGAGGAAGGG--------
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------VGGQGTAGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------IGGQGTEGGTG--------
MMAR_4602|M.marinum_M               -------------------------------KGGTGGAAGAGG------M
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------DGIDGGTGGAGGMG-EIYS
TH_3810|M.thermoresistible__bu      -------------------------------SGVDG--------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------AGLAGNAGLAG--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGVVGDVGNAGIGGTGGKGGAGGTG-----------------FAGGA
Rv3508|M.tuberculosis_H37Rv         GGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGA
MUL_4367|M.ulcerans_Agy99           ---------VGAASLGGDGGHAGAGGAG----------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------GVGGIGGAGSTGAVGGVG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------GVGGVGGVGATGGAGGVG----------------------
MMAR_4602|M.marinum_M               GTDGGAAGANGTGGVGGTGGDGGAGGTGIAG-------TDDQVSPTAGHQ
MSMEG_0868|M.smegmatis_MC2_155      GADGEATGISAGGDGGSATGADSLGGRGGTS-------------------
TH_3810|M.thermoresistible__bu      --------------------VDVVGGN-----------------------
MAB_4284c|M.abscessus_ATCC_199      -------------NAGLAGNAGLAGNAG----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------APPPVQASAPQPKISVPEP---------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGG----
Rv3508|M.tuberculosis_H37Rv         GGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGF----
MUL_4367|M.ulcerans_Agy99           -GEGLSGGFN----------TGAAGGIGGAGGAGGTGGD-----------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------GKGIQGGQGLQGGKGGD-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------GKGIQGGQGLQGGQGGD-----------
MMAR_4602|M.marinum_M               GGQGGMGGTGGDGGAGIGGVGGGAGGKGGVGGAGGTGGQ-----------
MSMEG_0868|M.smegmatis_MC2_155      --WVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGV
TH_3810|M.thermoresistible__bu      ----------------------------PDGGTPG---------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------LAGNAGLAGNAGLAGN-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------VAAPKPLSPPVAAPLP-----------
                                                                                      

Mb3538|M.bovis_AF2122/97            ---AGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIG---------
Rv3508|M.tuberculosis_H37Rv         ---AGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDG
MUL_4367|M.ulcerans_Agy99           ---SGGVGGVNGDGGAGGGGGRGGDGGS-----STSTSGVG---------
Mflv_5091|M.gilvum_PYR-GCK          ----GGAGGKGGDADSMGSAG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----GGTGGTGGDATSMGEAG-----------------------------
MMAR_4602|M.marinum_M               ---GGGPGGTGGIASALDSGAGAQGGGIPSTTGVPGADGGKGGTG-----
MSMEG_0868|M.smegmatis_MC2_155      ATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGH-----
TH_3810|M.thermoresistible__bu      -------------------------------AHG----------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ----------------------------------GTGGTGGVGGAGGAGA
Rv3508|M.tuberculosis_H37Rv         GDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGA
MUL_4367|M.ulcerans_Agy99           ----------------------------------GAGGAGGNGGNAGFGV
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------ATGGKGGNGGNGGRGG
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------ATGGKGGNGGNGGRGS
MMAR_4602|M.marinum_M               ----------------------------------GTAGAAGVGVDGGAAG
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------GGAAQGGNGGNGGNGW
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AAAAGSSATGGAGFAGGAG-----------------GEGGAGGNSGVG-G
Rv3508|M.tuberculosis_H37Rv         TGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNG-G
MUL_4367|M.ulcerans_Agy99           SAGG----TGGSAGDGGAG-------------------GGAGGVDGVG-G
Mflv_5091|M.gilvum_PYR-GCK          LFGKG--GNAGNGADG-----------------------GTGGAGGAG-G
Mvan_1264|M.vanbaalenii_PYR-1       LFGRG--GNAGNGGNG-----------------------GTGGNGGNG-G
MMAR_4602|M.marinum_M               SIGAG--GVGGTGGNGGAGADNDVNGTSG----TAPTAGGQGGQGGQG-G
MSMEG_0868|M.smegmatis_MC2_155      VQAYDPNGPAGTTIDKGKAAG---------------GNGGDGGFNGTGGA
TH_3810|M.thermoresistible__bu      -ESHTP----GVYTDRQ----------------------GEDGEDGTGTG
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------AGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------AAPPPAAPPLP
                                                                                      

Mb3538|M.bovis_AF2122/97            TNGSGGAG---------GAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGG
Rv3508|M.tuberculosis_H37Rv         AGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGG
MUL_4367|M.ulcerans_Agy99           ASGNGGAA---------GAGGAGGSGIGAG-------IDGGAGGAGGTGG
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGAG---------GTGGTGGTG--------------GIGGAGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGNG---------GTGGTGGTG--------------GIGGAGSTGG
MMAR_4602|M.marinum_M               QGGDGGSGIG---GVGGGAGGHGGIGGSGGAGSNGGNNTGSTGGVGADGG
MSMEG_0868|M.smegmatis_MC2_155      TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGG
TH_3810|M.thermoresistible__bu      IGGRGGNGG-----SSSGTHPMAE--------------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAG------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                EAPPIPAAPP----------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AAGAGGAG--------------GATGTGGTGGVVGATGSAGIGGAGGRGG
Rv3508|M.tuberculosis_H37Rv         KGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGG
MUL_4367|M.ulcerans_Agy99           AAGFPGGG--------------GTTGAWGTGGAGGAGGAGGAGDHGGVGV
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTG-----------------GTGGTGGTGGTGGTGGTGGTGGKG-
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTG-----------------GTGGTGGTGGTGGTGGTGGTGGKG-
MMAR_4602|M.marinum_M               KGGTGGTAG--------------AAGVGVDGGAAGSIGTGGVGGTGGNGG
MSMEG_0868|M.smegmatis_MC2_155      AGGAGGVSE----------------GEGGTGGHGGDGGRGGDGALGGNGG
TH_3810|M.thermoresistible__bu      ---------------------------------DGEHVKALDGRPGLDG-
MAB_4284c|M.abscessus_ATCC_199      --------------------------LAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------VVPVPVVVPPVPVPVPVRIPVPDPV
                                                                                      

Mb3538|M.bovis_AF2122/97            DGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGINGAGGAGGDGGDGGD
Rv3508|M.tuberculosis_H37Rv         DGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGD
MUL_4367|M.ulcerans_Agy99           NPGD------SGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGG
Mflv_5091|M.gilvum_PYR-GCK          ------------------GTGGTGGAGGTGGDGGTGGTGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GTGGTGGDGGTGGTGGTGGTGGTGGTGGTGGT
MMAR_4602|M.marinum_M               AGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGGVGGGAGGHGGV
MSMEG_0868|M.smegmatis_MC2_155      TGGV------------GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN
TH_3810|M.thermoresistible__bu      ------------------GNGSHGGNGGHGGRGG------FLGIGGSGGW
MAB_4284c|M.abscessus_ATCC_199      ----------------LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SPPQ------------LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ
                                                                                      

Mb3538|M.bovis_AF2122/97            GATG----AAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGN
Rv3508|M.tuberculosis_H37Rv         GATG----AAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGN
MUL_4367|M.ulcerans_Agy99           GGAG----ASGIG-AGVAGGDGGTGGTGG-----------AAGTGGAAGT
Mflv_5091|M.gilvum_PYR-GCK          GGTG----GAGDG----TGGTGGTGGTGG-----------QGGQGGQGGT
Mvan_1264|M.vanbaalenii_PYR-1       GGTG----GAGDG----LGGTGGTGGTGG-----------FGGQGGQGGT
MMAR_4602|M.marinum_M               GGSG----GAGSNGGNNTGSTGGVGADGG-----------KGGTGGTAGA
MSMEG_0868|M.smegmatis_MC2_155      GGAGRIRVNNGTATGTATGGNGGNGGNGD-------------ADGHRGGK
TH_3810|M.thermoresistible__bu      G------------------GHGGNGGDTD-------------ADGGNGGD
MAB_4284c|M.abscessus_ATCC_199      LNTG------------VSGAIGGSSHVGG------------AINESLGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                SPPQ-------------HQTPPGEGTPPK-----------------PDGP
                                                                                      

Mb3538|M.bovis_AF2122/97            GGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGN
Rv3508|M.tuberculosis_H37Rv         GGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGN
MUL_4367|M.ulcerans_Agy99           GGTGGAAGAAGS-----------------------------------AGD
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGLGGG--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGQGGLGGV--------------------------------------
MMAR_4602|M.marinum_M               AGVGVDGGAAGS-----------------------------------IGT
MSMEG_0868|M.smegmatis_MC2_155      GGDGGEALIRAT---------------------------VIGSNASGTAT
TH_3810|M.thermoresistible__bu      GGNGG--------------------------------------------S
MAB_4284c|M.abscessus_ATCC_199      GSVGGSTAVGGG--------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GNYGGGHVPTPG-------------------------------------A
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGGGGFGGAAGKAGGGGN
Rv3508|M.tuberculosis_H37Rv         GGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGN
MUL_4367|M.ulcerans_Agy99           GGAGGAGGAGDDGSAGVVS-----GDPGTAGKAGG-----------AGGA
Mflv_5091|M.gilvum_PYR-GCK          GGTGGQGGTGG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGTGGTGGTGG---------------------------------------
MMAR_4602|M.marinum_M               GGVGGQGGDGGSGGTGALGADGTNPTGGGRGGQGG-----------QGGQ
MSMEG_0868|M.smegmatis_MC2_155      GGDGGNGGTLGATNGTGGAATIVAYNVVQANP------------------
TH_3810|M.thermoresistible__bu      AGRGGTGGLRGVF-------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -AHTGVGGGVSTG-------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGSGGSGGGHVPTP------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAGAGGINGAGGTGGTG
Rv3508|M.tuberculosis_H37Rv         GGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTG
MUL_4367|M.ulcerans_Agy99           GGVGGN-------------GVAGGVNGSGGAG---------GAGGAGGTG
Mflv_5091|M.gilvum_PYR-GCK          ---------------------TGGQGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------TGGQGGTGGTG---------GTGGTGGTG
MMAR_4602|M.marinum_M               GGDGGS-------------GIGGVGGGAGGHG---------GVGGSGGTG
MSMEG_0868|M.smegmatis_MC2_155      ---------------------QASGTATDGHG---------GSGINGGHG
TH_3810|M.thermoresistible__bu      -------------------------------------------GINGGNG
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------VGVGSHVGGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------GAGGSGGSG
                                                                                      

Mb3538|M.bovis_AF2122/97            GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGIGG----
Rv3508|M.tuberculosis_H37Rv         GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGF
MUL_4367|M.ulcerans_Agy99           GAGASGVPASVDGG-DGGAGGAGGAAGTGG--------------------
Mflv_5091|M.gilvum_PYR-GCK          GAGG-----------DGGLGGLGGFGGSGG--------------------
Mvan_1264|M.vanbaalenii_PYR-1       GAGG-----------DGGLGGLGGFGGVGG--------------------
MMAR_4602|M.marinum_M               GTGGSNTASTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSIG--------
MSMEG_0868|M.smegmatis_MC2_155      GNGGQGTIEANGPSAVASGIGAGGNGGDGI--------------------
TH_3810|M.thermoresistible__bu      R-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ISES----------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGHVP---------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            ------TGGAGGAGGAGGAGDAGADGDPSIDGGQGGAGGHGGQGGKGGLN
Rv3508|M.tuberculosis_H37Rv         GAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLN
MUL_4367|M.ulcerans_Agy99           ------SGGSAGNTGAGGAG---------------GAGGAGGSAASTGVN
Mflv_5091|M.gilvum_PYR-GCK          ------TGGQGGLGGPGGSTG--------------GAGGAGGQAGTAGKG
Mvan_1264|M.vanbaalenii_PYR-1       ------TGGQGGQGGPGGSTG--------------GAGGAGGQAGVAGKG
MMAR_4602|M.marinum_M               ------TGGVGGTGGEGGSGGTGVAGASGITPAVGGPGGQGGAGGTGGDG
MSMEG_0868|M.smegmatis_MC2_155      ------DGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQG
TH_3810|M.thermoresistible__bu      -------AGLGGRGXX----------------------XXGGGVGAAVRS
MAB_4284c|M.abscessus_ATCC_199      ------LGGSGSVGGSTAVGG----------------GAHTGVGGGVSTG
MLBr_01183|M.leprae_Br4923          ---------------------------------------MPLFLNAEPQA
MAV_4827|M.avium_104                ------TPGTGGPGGTGGSGG-----------------GHVPTPGAGTPG
                                                                                      

Mb3538|M.bovis_AF2122/97            STGLASAASGDGGNGGAGGAGGNGGD---------GDGFIGGSGGTGGTG
Rv3508|M.tuberculosis_H37Rv         STGLASAASGDGGNGGAGGAGGNGGD---------GDGFIGGSGGTGGTG
MUL_4367|M.ulcerans_Agy99           ---------GDGGAGGAGGVGGLGGD---------SAATAGG-GGAGGDG
Mflv_5091|M.gilvum_PYR-GCK          -----------GLFGGSGSAG--------------KAGATGAAGASGGKG
Mvan_1264|M.vanbaalenii_PYR-1       -----------GLFGGSGSAG--------------TAGVTGASGASGGKG
MMAR_4602|M.marinum_M               GAGIDGVGGGAGGQGGQGGAGGNGGMGGTYTGTGPGSSASGGTGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      ------------GNGGP-------------------SWVQSGYGSTLG-G
TH_3810|M.thermoresistible__bu      ------------GNG-----------------------VFSGGG------
MAB_4284c|M.abscessus_ATCC_199      -----------VGVGSHVGGG--------------ISESLGGSGSVGGST
MLBr_01183|M.leprae_Br4923          --------------------------------------LTAAANTLEGLS
MAV_4827|M.avium_104                -------------------------------------GSGGGHLPFPGAG
                                                                            ..        

Mb3538|M.bovis_AF2122/97            GDAGAGGLA-NTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQ
Rv3508|M.tuberculosis_H37Rv         GDAGVGGLA-NTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQ
MUL_4367|M.ulcerans_Agy99           GKGGAGGAG-VNGVGGGDGGKGGTGGAGGAGGAGSDGIIPSNG-----GL
Mflv_5091|M.gilvum_PYR-GCK          AQGATGAQG-ATGAQGATGATGAAGKAGATGAAGAAGAA---------GS
Mvan_1264|M.vanbaalenii_PYR-1       AQGATGAQG-ATGAQGATGATGASGAQGSAGSAGSAGVA---------GS
MMAR_4602|M.marinum_M               GDGGAPGAGSTTGGVGGNGGKGGNGGFGAGNSSGSSAGFGFGGGGGGGGA
MSMEG_0868|M.smegmatis_MC2_155      NATGTATAG--KGGEASNGGVAGNGGNALVMAAGTTGVAT--------GN
TH_3810|M.thermoresistible__bu      ---GTPSAG--FGVPTT---IQFPAGSCTSRAVSREGIMP--------SS
MAB_4284c|M.abscessus_ATCC_199      AVGGGAHTG-VGGGVNTGVGVGSHVGGGISESLGGSGSVG--------GS
MLBr_01183|M.leprae_Br4923          AATVASNAA--AAQLTTEIAPPAADDVSILLAHFFSGHGR--------QY
MAV_4827|M.avium_104                STPGGSGGG-HLPTPGAGTPGGGLGGFGGGHAPAPGGGLG----------
                                            .                      .    .             

Mb3538|M.bovis_AF2122/97            GGQGGAGGNAGAGGING-AGGTGGTGGAGGDGAPATLIGGPDGGDGGQGG
Rv3508|M.tuberculosis_H37Rv         GGQGGVGGNAGAGGING-AGGTGGTGGAGGDGQNGTTGVASEGGAGGQGG
MUL_4367|M.ulcerans_Agy99           GGNGGNGGNGGQAFGDG-VGGAGGIGGKGGNAAIGTIVIN--GGVGGAGG
Mflv_5091|M.gilvum_PYR-GCK          AGTTGAQGSAGTNGANG-ANGSQGAAGKAG--ATGT--------------
Mvan_1264|M.vanbaalenii_PYR-1       AGTTGAQGSAGTNGANG-ANGSQGAAGKAG--ATGT--------------
MMAR_4602|M.marinum_M               GGHGGNGGGGGASGGQGGAGGDGGLGGTAVSPTTGSAAGGGFGGGGGGGG
MSMEG_0868|M.smegmatis_MC2_155      TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG
TH_3810|M.thermoresistible__bu      RAASARAGAACASSTSRSRRSFCCSRA-----------------------
MAB_4284c|M.abscessus_ATCC_199      TAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINES----------
MLBr_01183|M.leprae_Br4923          QAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL--------------
MAV_4827|M.avium_104                GGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-----------------
                                     .                  .     .                       

Mb3538|M.bovis_AF2122/97            ------------GAGFGSGVAG----------------------------
Rv3508|M.tuberculosis_H37Rv         DGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQ
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               NATG----------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GKGA----------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------AAGAGGNGGKG-----GD
Rv3508|M.tuberculosis_H37Rv         GGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGTGGTG-----------------------------------------GT
Rv3508|M.tuberculosis_H37Rv         GGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGN
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            NFAGGQGG------------------AGGRGGAGGNGANG----------
Rv3508|M.tuberculosis_H37Rv         GFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGA
MUL_4367|M.ulcerans_Agy99           --------------------------SGGLGGATEDGVGG----------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------TGATGAAGEDGDAG----------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------TGATGAAGDAGDPG----------
MMAR_4602|M.marinum_M               -------------------------AAGGTGGGGGGGGAG----------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------DGWVQAYDPAGPVG----------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------MNSSINASHSSSMN-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPS
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4602|M.marinum_M               --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            --------------------------------VGDNAAGGDGGNGGAGGL
Rv3508|M.tuberculosis_H37Rv         IDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGAGGL
MUL_4367|M.ulcerans_Agy99           ----------------------------------VGCAGGAGGNGGRG--
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------------SGGSGINGGAG--
Mvan_1264|M.vanbaalenii_PYR-1       -------------------------------------SEAVDINGGAG--
MMAR_4602|M.marinum_M               ------------------------------AAAAVAAAGGGGGGGGAAG-
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------SKIANSSAVAGNGGDGGV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GGGGGTGGTNGNGGLGGGGGNGGAGG-----AGGTPTGSGTEGTGGDGGD
Rv3508|M.tuberculosis_H37Rv         GGGGGTGGTNGNGGLGGGGGNGGAGG-----AGGTPTGSGTEGTGGDGGD
MUL_4367|M.ulcerans_Agy99           ---------DMLFTVGGSGGTGGDGG-----GGGSASGSGTGGSGGTGGV
Mflv_5091|M.gilvum_PYR-GCK          -------------GAGGAGGEGGEGG-----DGG---------KGGAGAE
Mvan_1264|M.vanbaalenii_PYR-1       -------------GAGGAGGEGGEGG-----AGG---------AGGDGSE
MMAR_4602|M.marinum_M               -------------GPGGTAGNGGVGGNA--FGGGSSGTGGTAGAGAPGGV
MSMEG_0868|M.smegmatis_MC2_155      N-----------GTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------ESFGSSMGSHGAAG------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            AGAGGNGGSATG--VGNGGNGGDGGNGGDGGNG-----APGGFGGGAGAG
Rv3508|M.tuberculosis_H37Rv         AGAGGNGGSATG--VGNGGNGGDGGNGGDGGNG-----APGGFGGGAGAG
MUL_4367|M.ulcerans_Agy99           GGIGGDGK--------LGGFGGDGGDGGDGGFG-----VIGGQGGGGGFG
Mflv_5091|M.gilvum_PYR-GCK          GGAGGGGG---------AGGSGAGGAGGAGGSG-----GSGGSGGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1       GGAGGSGG---------AGGSGTGGAGGAGGSG-----GSGGSGGAGGSG
MMAR_4602|M.marinum_M               GGGGGGGAVAQSSFANNGGPGRDGADGGDGGAGGFIIGTYGGNGGGAAGA
MSMEG_0868|M.smegmatis_MC2_155      GGDGSEPG---------PGGNGAGGAGGNGGTG-------GTTAGGSGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------TGFEAQGHAQGHASET-----AHTTLPGAEHH-
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mb3538|M.bovis_AF2122/97            GLGGSGAGGGTDGDDGNGGSPGTDGS
Rv3508|M.tuberculosis_H37Rv         GLGGSGAGGGTDGDDGNGGSPGTDGS
MUL_4367|M.ulcerans_Agy99           GLGGTGAGG-APSDKGINGEPGNPG-
Mflv_5091|M.gilvum_PYR-GCK          GAAG-------DSDD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GAAG-------DSD------------
MMAR_4602|M.marinum_M               GGGGGAAFNVVATAQGGQGQSG----
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      --------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------
MLBr_01183|M.leprae_Br4923          --------------------------
MAV_4827|M.avium_104                --------------------------