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LSYVTAAPEALAAAAGDLTGIGEALRAATAAAAPSTTSLVAAAGDEVSTAIATLFSEHAQSYQALSAQMA AFHDRFMNALAGASGSYASAEAANVTPLQTIEQDLLGAVNAPTQVLFGRGLIGDGANGTAPGQAGGAGGL LIGNGGNGAPGAVGQAGGAGGAAGLLGNGGTGGAGGAGANGGAGGSAGLWGAGGAGGAGGAGATPGGAGG AGGTGGANGLVGGGNGGAGGAGGVGGTGATGTTGGVGGDGGAGGAGGVGGVDRALIGWSGGAGGVGGSGG AGGLGGTGSAGAGLGATGGDGGAGGVGGQAGAGGAGGAVTGSINPLGNAGAHGANGTGGVGGTGGVGGAG GTGIAGTGDLVSPTAGYQGGQGGMGGKGGDGGAGIGGVGGGAGGEGGVGGAGGTGGQGGANTGATGGMGA DGGKGGTGGAAGAGGMGTDGGAAGANGTGGVGGTGGDGGAGGTGIAGTDDQVSPTAGHQGGQGGMGGTGG DGGAGIGGVGGGAGGKGGVGGAGGTGGQGGGPGGTGGIASALDSGAGAQGGGIPSTTGVPGADGGKGGTG GTAGAAGVGVDGGAAGSIGAGGVGGTGGNGGAGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGG VGGGAGGHGGIGGSGGAGSNGGNNTGSTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSIGTGGVGGTGGN GGAGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGGVGGGAGGHGGVGGSGGAGSNGGNNTGSTG GVGADGGKGGTGGTAGAAGVGVDGGAAGSIGTGGVGGQGGDGGSGGTGALGADGTNPTGGGRGGQGGQGG QGGDGGSGIGGVGGGAGGHGGVGGSGGTGGTGGSNTASTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSI GTGGVGGTGGEGGSGGTGVAGASGITPAVGGPGGQGGAGGTGGDGGAGIDGVGGGAGGQGGQGGAGGNGG MGGTYTGTGPGSSASGGTGGAGGAGGDGGAPGAGSTTGGVGGNGGKGGNGGFGAGNSSGSSAGFGFGGGG GGGGAGGHGGNGGGGGASGGQGGAGGDGGLGGTAVSPTTGSAAGGGFGGGGGGGGNATGAAGGTGGGGGG GGAGAAAAVAAAGGGGGGGGAAGGPGGTAGNGGVGGNAFGGGSSGTGGTAGAGAPGGVGGGGGGGAVAQS SFANNGGPGRDGADGGDGGAGGFIIGTYGGNGGGAAGAGGGGGAAFNVVATAQGGQGQSG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4602 | - | - | 100% (1251) | PE-PGRS family protein |
M. marinum M | MMAR_5294 | - | 0.0 | 48.47% (1471) | PE-PGRS family protein |
M. marinum M | MMAR_2033 | - | 0.0 | 51.04% (1348) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3538 | PE_PGRS54 | 0.0 | 49.09% (1477) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 47.03% (859) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 46.73% (1558) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 3e-13 | 41.30% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 2e-53 | 33.03% (545) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 2e-26 | 44.21% (190) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-173 | 42.70% (1075) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-44 | 37.07% (348) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 50.09% (1134) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 45.05% (868) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -----------------------------------------MSFVLIAPE Rv3508|M.tuberculosis_H37Rv -----------------------------------------MSFVLIAPE MUL_4367|M.ulcerans_Agy99 -----------------------------------------MSFVSVGPG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M ----------------------------------------MLSYVTAAPE MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------MSIIDFILNLFR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------MNIVLGVSMAPS Mb3538|M.bovis_AF2122/97 FVTAAAGDLTNLGSSISAANASAASATTQVLAAG---------------- Rv3508|M.tuberculosis_H37Rv FVTAAAGDLTNLGSSISAANASAASATTQVLAAG---------------- MUL_4367|M.ulcerans_Agy99 LLEAAARDLAGLGAGLREANLAAAGATVGVLPAA---------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------MMFLAPPGGPGPISAAIQLTSTG---------------- MMAR_4602|M.marinum_M ALAAAAGDLTGIGEALRAATAAAAPSTTSLVAAA---------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 DPVEAASYVADPEAALANAGLSAVSAAQVGAVMP---------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SIQMVVLEGEYADGATVEEDAIDVTGADDAATAS---------------- Mb3538|M.bovis_AF2122/97 ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS Rv3508|M.tuberculosis_H37Rv ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS MUL_4367|M.ulcerans_Agy99 ----GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ Mflv_5091|M.gilvum_PYR-GCK ------------MVTFGGGA------TPTPTSLGAAAVDLSGTSCG---- Mvan_1264|M.vanbaalenii_PYR-1 ----SEATEPWYVVSFGGSG------APTPNNLAASLVDLSGTSCG---- MMAR_4602|M.marinum_M ----GDEVSTAIATLFSEHAQSYQALSAQMAAFHDRFMNALAGASGSYAS MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------APDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDAL Mb3538|M.bovis_AF2122/97 AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT Rv3508|M.tuberculosis_H37Rv AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT MUL_4367|M.ulcerans_Agy99 AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------LICNGQD--- MMAR_4602|M.marinum_M AEAANVTPLQ---------TIEQDLLGAVNAPTQVLFGRGLIGDGAN-GT MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------PSILSPSLLSPRDNDFL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AARR---------------------------IDNVMLVSAFLAAAALAQN Mb3538|M.bovis_AF2122/97 TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG Rv3508|M.tuberculosis_H37Rv TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-- Mflv_5091|M.gilvum_PYR-GCK ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG-- Mvan_1264|M.vanbaalenii_PYR-1 ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG-- MMAR_4602|M.marinum_M APGQAGGAGGLLIGNGGNGA-PGAVGQAGGAGGAAGLLGNGGTGGAGG-- MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGW-- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRD-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG---- Mb3538|M.bovis_AF2122/97 GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGG Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGG MUL_4367|M.ulcerans_Agy99 ---------------VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAG Mflv_5091|M.gilvum_PYR-GCK ------------------------LGGGNGGNGGNAGAFALFGN------ Mvan_1264|M.vanbaalenii_PYR-1 ------------------------LGSGDGGNGGDAGLFSLFGR------ MMAR_4602|M.marinum_M -------------------------AGANGGAGGSAG-LWGAGGAGGAGG MSMEG_0868|M.smegmatis_MC2_155 -------------------------AGLDGGNGGSGGLLMGIGGAGGAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------TTAIGDGAVAVGGSNSG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------DAAGQLSAMVAGLEKLESLPG Mb3538|M.bovis_AF2122/97 AGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHGGVGGDGG Rv3508|M.tuberculosis_H37Rv AGGGTGGAGGRAELLFGAGGAGGAG---TDGGPGATGGTGGHGGVGGDGG MUL_4367|M.ulcerans_Agy99 AGG-----------------------------------------SGGSGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M AG------------------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 VGADG--------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 G------------------------------------------------- Mb3538|M.bovis_AF2122/97 WLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLG Rv3508|M.tuberculosis_H37Rv WLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLG MUL_4367|M.ulcerans_Agy99 WLWG----NAGQTAGAG-----------VGGAGGAGGAGDAGDQGVSGVA Mflv_5091|M.gilvum_PYR-GCK -----------------------------GGNGGNGGVGVVG-------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------GGNGGNGGVGIAG-------- MMAR_4602|M.marinum_M -ATPGGAGGAGGTGGANG--------LVGGGNGGAGGAGGVGGTG----A MSMEG_0868|M.smegmatis_MC2_155 -TSAHVDGGTGGTGGTG------------GGTGGTGGIGGTGGGLFGLLG TH_3810|M.thermoresistible__bu -----VD----GDGGSG------------GRTG-----------LFSKLS MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AGGQGGLGGAGGQGGTGGAGGD-----GVLGGVGGTGGKGGVGGVAGLGG Rv3508|M.tuberculosis_H37Rv AGGQGGLGGAGGQGGTGGAGGD-----GVLGGVGGTGGKGGVGGVAGLGG MUL_4367|M.ulcerans_Agy99 PGEAGAVGFAGGAGGAGGAGGN-----GVGGGVNGAGGAGGAGGVGGGGG Mflv_5091|M.gilvum_PYR-GCK -----ATGAVGAPGVAGATGAT-----GVTSGVVGGNGEDAVG----YGA Mvan_1264|M.vanbaalenii_PYR-1 -----ATGAVGAPGVAGATGAT-----GVTSNVTGGNGADAVG----YGA MMAR_4602|M.marinum_M TGTTGGVGGDGGAGGAGGVGGVDRALIGWSGGAGGVGGSGGAGGLGGTGS MSMEG_0868|M.smegmatis_MC2_155 HSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGTGG TH_3810|M.thermoresistible__bu R------------GGDGGDGGLG--------------------------- MAB_4284c|M.abscessus_ATCC_199 -------PIASGQGSTAVNGDVR------DSNIINADHGSNVGVDQSQTR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------LLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAA Mb3538|M.bovis_AF2122/97 AGGAAGQLFSAGGAAGAVGVGGTGGQGGAG-------------------- Rv3508|M.tuberculosis_H37Rv AGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLTGGTG MUL_4367|M.ulcerans_Agy99 AG--------------ASGVG----------------------------- Mflv_5091|M.gilvum_PYR-GCK TG------------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 TG------------------------------------------------ MMAR_4602|M.marinum_M AG---------------AGLG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 QS------------------------------------------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VG------------------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AN------------------------------------------------ Mb3538|M.bovis_AF2122/97 ------------------------------------GMGGSGADNASGIG Rv3508|M.tuberculosis_H37Rv FAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGSGADNASGIG MUL_4367|M.ulcerans_Agy99 ------------------------------------------------AG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M -----------------------------------------------ATG MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------T TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------------AP Mb3538|M.bovis_AF2122/97 ADGGAGGTGGNAGAGGAGGAAG----TGGTGGVVGAAGKAGIGGTGGQGG Rv3508|M.tuberculosis_H37Rv ADGGAGGTGGNAGAGGAGGAAG----TGGTGGVVGAAGKAGIGGTGGQGG MUL_4367|M.ulcerans_Agy99 VAGGDGGTGGAGGAAGVGGAAG----TGGTG------GAAGVAGTGGDGG Mflv_5091|M.gilvum_PYR-GCK -AAGAAGAAGAAGAAGAVGSAG----AAGEAGETGTWGNAGLPGKAG--D Mvan_1264|M.vanbaalenii_PYR-1 -AAGAAGAAGAAGKAGAVGSAG----TAGSAGAPGVWGNAGLPGAAG--A MMAR_4602|M.marinum_M GDGGAGGVGGQAGAGGAGGAVTGSINPLGNAGAHGANGTGGVGGTGGVGG MSMEG_0868|M.smegmatis_MC2_155 AAGPGKGGGGGGGGGGAILIGAN----GGTVDGHAIGGNGGNGGNGSTTA TH_3810|M.thermoresistible__bu ------GNGGHGGGTGIISLLS-------------LAGNGGNGGNGYRTT MAB_4284c|M.abscessus_ATCC_199 ---GDYTNVSGHGSADIDKSVT-------VVDDHSQRNTTNINDSFNTDR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEE Mb3538|M.bovis_AF2122/97 AGGAGSAGTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGT Rv3508|M.tuberculosis_H37Rv AGGAGSAGTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGT MUL_4367|M.ulcerans_Agy99 DGGAGGAGSDASLAGQAG---FAGGSGGAGGVGGSAGAGGVNGSGGDGGA Mflv_5091|M.gilvum_PYR-GCK AGGAGAVG-AAGAAGTVG----TAGATGGTGTGANGGAGGVGGVGGTGAA Mvan_1264|M.vanbaalenii_PYR-1 AGGAGAIG-TAGVAGAAG----TAGATGGTGVGGNGGAGQAGGIGGTGAA MMAR_4602|M.marinum_M AGGTGIAGTGDLVSPTAG---YQGGQGGMGGKGGDGGAGIGGVGGGAGGE MSMEG_0868|M.smegmatis_MC2_155 AGGNGGTGGTGRVIAEGT-----GSTAEGTATGGDGGHSTGTGIGGNGGI TH_3810|M.thermoresistible__bu DNN--------------------------ALDGGHGGN------GGNVGF MAB_4284c|M.abscessus_ATCC_199 STNIGSGNTTNTEIGSHN----QANIGTSTSAGGSAAVGGNAGLAGNAGL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 DAESPTVVIEKLFLPEDS---EPRRRPVLLVGSGLAVVGISAVLALEIAL Mb3538|M.bovis_AF2122/97 GGAGGAGGAGGVGADNPTGIGGAGGTGG---------------------- Rv3508|M.tuberculosis_H37Rv GGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGS MUL_4367|M.ulcerans_Agy99 GAAGGAGGASAT-------VAGSGGVGG---------------------- Mflv_5091|M.gilvum_PYR-GCK GAAGGAGGLGET--------GTTGGAGG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 GAAGQAGTAGET--------GVTGGVGG---------------------- MMAR_4602|M.marinum_M GGVGGAGGTGGQGGANTGATGGMGADGG---------------------- MSMEG_0868|M.smegmatis_MC2_155 GSVYAYGNNGAVSG------TATGGRGG---------------------- TH_3810|M.thermoresistible__bu FSLFNLG--------------GAGGWGG---------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG-------NAGLAGN---------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AIGIRTTGTVALQPTPNQHLIVPTEQAP---------------------- Mb3538|M.bovis_AF2122/97 ----------------------------AGGTGGTGGAAGAGGAGGAVGT Rv3508|M.tuberculosis_H37Rv GGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGT MUL_4367|M.ulcerans_Agy99 -------------------------------DGGAGGAAGGG-------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------VGGQGTAGGTG-------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------IGGQGTEGGTG-------- MMAR_4602|M.marinum_M -------------------------------KGGTGGAAGAGG------M MSMEG_0868|M.smegmatis_MC2_155 -------------------------------DGIDGGTGGAGGMG-EIYS TH_3810|M.thermoresistible__bu -------------------------------SGVDG-------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------AGLAGNAGLAG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGTGGVVGDVGNAGIGGTGGKGGAGGTG-----------------FAGGA Rv3508|M.tuberculosis_H37Rv GGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGA MUL_4367|M.ulcerans_Agy99 ---------VGAASLGGDGGHAGAGGAG---------------------- Mflv_5091|M.gilvum_PYR-GCK ----------GVGGIGGAGSTGAVGGVG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------GVGGVGGVGATGGAGGVG---------------------- MMAR_4602|M.marinum_M GTDGGAAGANGTGGVGGTGGDGGAGGTGIAG-------TDDQVSPTAGHQ MSMEG_0868|M.smegmatis_MC2_155 GADGEATGISAGGDGGSATGADSLGGRGGTS------------------- TH_3810|M.thermoresistible__bu --------------------VDVVGGN----------------------- MAB_4284c|M.abscessus_ATCC_199 -------------NAGLAGNAGLAGNAG---------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------APPPVQASAPQPKISVPEP--------------------- Mb3538|M.bovis_AF2122/97 GGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGG---- Rv3508|M.tuberculosis_H37Rv GGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGF---- MUL_4367|M.ulcerans_Agy99 -GEGLSGGFN----------TGAAGGIGGAGGAGGTGGD----------- Mflv_5091|M.gilvum_PYR-GCK ----------------------GKGIQGGQGLQGGKGGD----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GKGIQGGQGLQGGQGGD----------- MMAR_4602|M.marinum_M GGQGGMGGTGGDGGAGIGGVGGGAGGKGGVGGAGGTGGQ----------- MSMEG_0868|M.smegmatis_MC2_155 --WVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGV TH_3810|M.thermoresistible__bu ----------------------------PDGGTPG--------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------LAGNAGLAGNAGLAGN----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------VAAPKPLSPPVAAPLP----------- Mb3538|M.bovis_AF2122/97 ---AGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIG--------- Rv3508|M.tuberculosis_H37Rv ---AGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDG MUL_4367|M.ulcerans_Agy99 ---SGGVGGVNGDGGAGGGGGRGGDGGS-----STSTSGVG--------- Mflv_5091|M.gilvum_PYR-GCK ----GGAGGKGGDADSMGSAG----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----GGTGGTGGDATSMGEAG----------------------------- MMAR_4602|M.marinum_M ---GGGPGGTGGIASALDSGAGAQGGGIPSTTGVPGADGGKGGTG----- MSMEG_0868|M.smegmatis_MC2_155 ATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGH----- TH_3810|M.thermoresistible__bu -------------------------------AHG---------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 ----------------------------------GTGGTGGVGGAGGAGA Rv3508|M.tuberculosis_H37Rv GDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGA MUL_4367|M.ulcerans_Agy99 ----------------------------------GAGGAGGNGGNAGFGV Mflv_5091|M.gilvum_PYR-GCK ----------------------------------ATGGKGGNGGNGGRGG Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------ATGGKGGNGGNGGRGS MMAR_4602|M.marinum_M ----------------------------------GTAGAAGVGVDGGAAG MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------GGAAQGGNGGNGGNGW TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AAAAGSSATGGAGFAGGAG-----------------GEGGAGGNSGVG-G Rv3508|M.tuberculosis_H37Rv TGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNG-G MUL_4367|M.ulcerans_Agy99 SAGG----TGGSAGDGGAG-------------------GGAGGVDGVG-G Mflv_5091|M.gilvum_PYR-GCK LFGKG--GNAGNGADG-----------------------GTGGAGGAG-G Mvan_1264|M.vanbaalenii_PYR-1 LFGRG--GNAGNGGNG-----------------------GTGGNGGNG-G MMAR_4602|M.marinum_M SIGAG--GVGGTGGNGGAGADNDVNGTSG----TAPTAGGQGGQGGQG-G MSMEG_0868|M.smegmatis_MC2_155 VQAYDPNGPAGTTIDKGKAAG---------------GNGGDGGFNGTGGA TH_3810|M.thermoresistible__bu -ESHTP----GVYTDRQ----------------------GEDGEDGTGTG MAB_4284c|M.abscessus_ATCC_199 --------------------------------------AGLAGNAGLAGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------------------AAPPPAAPPLP Mb3538|M.bovis_AF2122/97 TNGSGGAG---------GAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGG Rv3508|M.tuberculosis_H37Rv AGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGG MUL_4367|M.ulcerans_Agy99 ASGNGGAA---------GAGGAGGSGIGAG-------IDGGAGGAGGTGG Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG---------GTGGTGGTG--------------GIGGAGSTGG Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGNG---------GTGGTGGTG--------------GIGGAGSTGG MMAR_4602|M.marinum_M QGGDGGSGIG---GVGGGAGGHGGIGGSGGAGSNGGNNTGSTGGVGADGG MSMEG_0868|M.smegmatis_MC2_155 TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGG TH_3810|M.thermoresistible__bu IGGRGGNGG-----SSSGTHPMAE-------------------------- MAB_4284c|M.abscessus_ATCC_199 AGLAGNAG------------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 EAPPIPAAPP---------------------------------------- Mb3538|M.bovis_AF2122/97 AAGAGGAG--------------GATGTGGTGGVVGATGSAGIGGAGGRGG Rv3508|M.tuberculosis_H37Rv KGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGG MUL_4367|M.ulcerans_Agy99 AAGFPGGG--------------GTTGAWGTGGAGGAGGAGGAGDHGGVGV Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG-----------------GTGGTGGTGGTGGTGGTGGTGGKG- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG-----------------GTGGTGGTGGTGGTGGTGGTGGKG- MMAR_4602|M.marinum_M KGGTGGTAG--------------AAGVGVDGGAAGSIGTGGVGGTGGNGG MSMEG_0868|M.smegmatis_MC2_155 AGGAGGVSE----------------GEGGTGGHGGDGGRGGDGALGGNGG TH_3810|M.thermoresistible__bu ---------------------------------DGEHVKALDGRPGLDG- MAB_4284c|M.abscessus_ATCC_199 --------------------------LAGNAGLAGNAGLAGNAGLAGNAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------VVPVPVVVPPVPVPVPVRIPVPDPV Mb3538|M.bovis_AF2122/97 DGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGINGAGGAGGDGGDGGD Rv3508|M.tuberculosis_H37Rv DGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGD MUL_4367|M.ulcerans_Agy99 NPGD------SGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAGGG Mflv_5091|M.gilvum_PYR-GCK ------------------GTGGTGGAGGTGGDGGTGGTGGTGGTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGDGGTGGTGGTGGTGGTGGTGGTGGT MMAR_4602|M.marinum_M AGADNDVNGTSGTAPTAGGQGGQGGQGGQGGDGGSGIGGVGGGAGGHGGV MSMEG_0868|M.smegmatis_MC2_155 TGGV------------GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN TH_3810|M.thermoresistible__bu ------------------GNGSHGGNGGHGGRGG------FLGIGGSGGW MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SPPQ------------LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ Mb3538|M.bovis_AF2122/97 GATG----AAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGN Rv3508|M.tuberculosis_H37Rv GATG----AAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGN MUL_4367|M.ulcerans_Agy99 GGAG----ASGIG-AGVAGGDGGTGGTGG-----------AAGTGGAAGT Mflv_5091|M.gilvum_PYR-GCK GGTG----GAGDG----TGGTGGTGGTGG-----------QGGQGGQGGT Mvan_1264|M.vanbaalenii_PYR-1 GGTG----GAGDG----LGGTGGTGGTGG-----------FGGQGGQGGT MMAR_4602|M.marinum_M GGSG----GAGSNGGNNTGSTGGVGADGG-----------KGGTGGTAGA MSMEG_0868|M.smegmatis_MC2_155 GGAGRIRVNNGTATGTATGGNGGNGGNGD-------------ADGHRGGK TH_3810|M.thermoresistible__bu G------------------GHGGNGGDTD-------------ADGGNGGD MAB_4284c|M.abscessus_ATCC_199 LNTG------------VSGAIGGSSHVGG------------AINESLGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 SPPQ-------------HQTPPGEGTPPK-----------------PDGP Mb3538|M.bovis_AF2122/97 GGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGN Rv3508|M.tuberculosis_H37Rv GGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAGGN MUL_4367|M.ulcerans_Agy99 GGTGGAAGAAGS-----------------------------------AGD Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGG-------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGLGGV-------------------------------------- MMAR_4602|M.marinum_M AGVGVDGGAAGS-----------------------------------IGT MSMEG_0868|M.smegmatis_MC2_155 GGDGGEALIRAT---------------------------VIGSNASGTAT TH_3810|M.thermoresistible__bu GGNGG--------------------------------------------S MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGG-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GNYGGGHVPTPG-------------------------------------A Mb3538|M.bovis_AF2122/97 GGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGGGGFGGAAGKAGGGGN Rv3508|M.tuberculosis_H37Rv GGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGN MUL_4367|M.ulcerans_Agy99 GGAGGAGGAGDDGSAGVVS-----GDPGTAGKAGG-----------AGGA Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGTGG--------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGG--------------------------------------- MMAR_4602|M.marinum_M GGVGGQGGDGGSGGTGALGADGTNPTGGGRGGQGG-----------QGGQ MSMEG_0868|M.smegmatis_MC2_155 GGDGGNGGTLGATNGTGGAATIVAYNVVQANP------------------ TH_3810|M.thermoresistible__bu AGRGGTGGLRGVF------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -AHTGVGGGVSTG------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGSGGSGGGHVPTP------------------------------------ Mb3538|M.bovis_AF2122/97 GGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAGAGGINGAGGTGGTG Rv3508|M.tuberculosis_H37Rv GGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTG MUL_4367|M.ulcerans_Agy99 GGVGGN-------------GVAGGVNGSGGAG---------GAGGAGGTG Mflv_5091|M.gilvum_PYR-GCK ---------------------TGGQGGTGGTG---------GTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 ---------------------TGGQGGTGGTG---------GTGGTGGTG MMAR_4602|M.marinum_M GGDGGS-------------GIGGVGGGAGGHG---------GVGGSGGTG MSMEG_0868|M.smegmatis_MC2_155 ---------------------QASGTATDGHG---------GSGINGGHG TH_3810|M.thermoresistible__bu -------------------------------------------GINGGNG MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VGVGSHVGGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------------GAGGSGGSG Mb3538|M.bovis_AF2122/97 GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGIGG---- Rv3508|M.tuberculosis_H37Rv GAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGF MUL_4367|M.ulcerans_Agy99 GAGASGVPASVDGG-DGGAGGAGGAAGTGG-------------------- Mflv_5091|M.gilvum_PYR-GCK GAGG-----------DGGLGGLGGFGGSGG-------------------- Mvan_1264|M.vanbaalenii_PYR-1 GAGG-----------DGGLGGLGGFGGVGG-------------------- MMAR_4602|M.marinum_M GTGGSNTASTGGVGADGGKGGTGGTAGAAGVGVDGGAAGSIG-------- MSMEG_0868|M.smegmatis_MC2_155 GNGGQGTIEANGPSAVASGIGAGGNGGDGI-------------------- TH_3810|M.thermoresistible__bu R------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ISES---------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGHVP--------------------------------------------- Mb3538|M.bovis_AF2122/97 ------TGGAGGAGGAGGAGDAGADGDPSIDGGQGGAGGHGGQGGKGGLN Rv3508|M.tuberculosis_H37Rv GAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLN MUL_4367|M.ulcerans_Agy99 ------SGGSAGNTGAGGAG---------------GAGGAGGSAASTGVN Mflv_5091|M.gilvum_PYR-GCK ------TGGQGGLGGPGGSTG--------------GAGGAGGQAGTAGKG Mvan_1264|M.vanbaalenii_PYR-1 ------TGGQGGQGGPGGSTG--------------GAGGAGGQAGVAGKG MMAR_4602|M.marinum_M ------TGGVGGTGGEGGSGGTGVAGASGITPAVGGPGGQGGAGGTGGDG MSMEG_0868|M.smegmatis_MC2_155 ------DGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQG TH_3810|M.thermoresistible__bu -------AGLGGRGXX----------------------XXGGGVGAAVRS MAB_4284c|M.abscessus_ATCC_199 ------LGGSGSVGGSTAVGG----------------GAHTGVGGGVSTG MLBr_01183|M.leprae_Br4923 ---------------------------------------MPLFLNAEPQA MAV_4827|M.avium_104 ------TPGTGGPGGTGGSGG-----------------GHVPTPGAGTPG Mb3538|M.bovis_AF2122/97 STGLASAASGDGGNGGAGGAGGNGGD---------GDGFIGGSGGTGGTG Rv3508|M.tuberculosis_H37Rv STGLASAASGDGGNGGAGGAGGNGGD---------GDGFIGGSGGTGGTG MUL_4367|M.ulcerans_Agy99 ---------GDGGAGGAGGVGGLGGD---------SAATAGG-GGAGGDG Mflv_5091|M.gilvum_PYR-GCK -----------GLFGGSGSAG--------------KAGATGAAGASGGKG Mvan_1264|M.vanbaalenii_PYR-1 -----------GLFGGSGSAG--------------TAGVTGASGASGGKG MMAR_4602|M.marinum_M GAGIDGVGGGAGGQGGQGGAGGNGGMGGTYTGTGPGSSASGGTGGAGGAG MSMEG_0868|M.smegmatis_MC2_155 ------------GNGGP-------------------SWVQSGYGSTLG-G TH_3810|M.thermoresistible__bu ------------GNG-----------------------VFSGGG------ MAB_4284c|M.abscessus_ATCC_199 -----------VGVGSHVGGG--------------ISESLGGSGSVGGST MLBr_01183|M.leprae_Br4923 --------------------------------------LTAAANTLEGLS MAV_4827|M.avium_104 -------------------------------------GSGGGHLPFPGAG .. Mb3538|M.bovis_AF2122/97 GDAGAGGLA-NTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQ Rv3508|M.tuberculosis_H37Rv GDAGVGGLA-NTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQ MUL_4367|M.ulcerans_Agy99 GKGGAGGAG-VNGVGGGDGGKGGTGGAGGAGGAGSDGIIPSNG-----GL Mflv_5091|M.gilvum_PYR-GCK AQGATGAQG-ATGAQGATGATGAAGKAGATGAAGAAGAA---------GS Mvan_1264|M.vanbaalenii_PYR-1 AQGATGAQG-ATGAQGATGATGASGAQGSAGSAGSAGVA---------GS MMAR_4602|M.marinum_M GDGGAPGAGSTTGGVGGNGGKGGNGGFGAGNSSGSSAGFGFGGGGGGGGA MSMEG_0868|M.smegmatis_MC2_155 NATGTATAG--KGGEASNGGVAGNGGNALVMAAGTTGVAT--------GN TH_3810|M.thermoresistible__bu ---GTPSAG--FGVPTT---IQFPAGSCTSRAVSREGIMP--------SS MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTG-VGGGVNTGVGVGSHVGGGISESLGGSGSVG--------GS MLBr_01183|M.leprae_Br4923 AATVASNAA--AAQLTTEIAPPAADDVSILLAHFFSGHGR--------QY MAV_4827|M.avium_104 STPGGSGGG-HLPTPGAGTPGGGLGGFGGGHAPAPGGGLG---------- . . . Mb3538|M.bovis_AF2122/97 GGQGGAGGNAGAGGING-AGGTGGTGGAGGDGAPATLIGGPDGGDGGQGG Rv3508|M.tuberculosis_H37Rv GGQGGVGGNAGAGGING-AGGTGGTGGAGGDGQNGTTGVASEGGAGGQGG MUL_4367|M.ulcerans_Agy99 GGNGGNGGNGGQAFGDG-VGGAGGIGGKGGNAAIGTIVIN--GGVGGAGG Mflv_5091|M.gilvum_PYR-GCK AGTTGAQGSAGTNGANG-ANGSQGAAGKAG--ATGT-------------- Mvan_1264|M.vanbaalenii_PYR-1 AGTTGAQGSAGTNGANG-ANGSQGAAGKAG--ATGT-------------- MMAR_4602|M.marinum_M GGHGGNGGGGGASGGQGGAGGDGGLGGTAVSPTTGSAAGGGFGGGGGGGG MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNG TH_3810|M.thermoresistible__bu RAASARAGAACASSTSRSRRSFCCSRA----------------------- MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINES---------- MLBr_01183|M.leprae_Br4923 QAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL-------------- MAV_4827|M.avium_104 GGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----------------- . . . Mb3538|M.bovis_AF2122/97 ------------GAGFGSGVAG---------------------------- Rv3508|M.tuberculosis_H37Rv DGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQ MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M NATG---------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GKGA---------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------------------------------AAGAGGNGGKG-----GD Rv3508|M.tuberculosis_H37Rv GGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGS MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGTGGTG-----------------------------------------GT Rv3508|M.tuberculosis_H37Rv GGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGN MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 NFAGGQGG------------------AGGRGGAGGNGANG---------- Rv3508|M.tuberculosis_H37Rv GFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGA MUL_4367|M.ulcerans_Agy99 --------------------------SGGLGGATEDGVGG---------- Mflv_5091|M.gilvum_PYR-GCK --------------------------TGATGAAGEDGDAG---------- Mvan_1264|M.vanbaalenii_PYR-1 --------------------------TGATGAAGDAGDPG---------- MMAR_4602|M.marinum_M -------------------------AAGGTGGGGGGGGAG---------- MSMEG_0868|M.smegmatis_MC2_155 --------------------------DGWVQAYDPAGPVG---------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------MNSSINASHSSSMN----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPS MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_4602|M.marinum_M -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 --------------------------------VGDNAAGGDGGNGGAGGL Rv3508|M.tuberculosis_H37Rv IDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGAGGL MUL_4367|M.ulcerans_Agy99 ----------------------------------VGCAGGAGGNGGRG-- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------SGGSGINGGAG-- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------SEAVDINGGAG-- MMAR_4602|M.marinum_M ------------------------------AAAAVAAAGGGGGGGGAAG- MSMEG_0868|M.smegmatis_MC2_155 --------------------------------SKIANSSAVAGNGGDGGV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GGGGGTGGTNGNGGLGGGGGNGGAGG-----AGGTPTGSGTEGTGGDGGD Rv3508|M.tuberculosis_H37Rv GGGGGTGGTNGNGGLGGGGGNGGAGG-----AGGTPTGSGTEGTGGDGGD MUL_4367|M.ulcerans_Agy99 ---------DMLFTVGGSGGTGGDGG-----GGGSASGSGTGGSGGTGGV Mflv_5091|M.gilvum_PYR-GCK -------------GAGGAGGEGGEGG-----DGG---------KGGAGAE Mvan_1264|M.vanbaalenii_PYR-1 -------------GAGGAGGEGGEGG-----AGG---------AGGDGSE MMAR_4602|M.marinum_M -------------GPGGTAGNGGVGGNA--FGGGSSGTGGTAGAGAPGGV MSMEG_0868|M.smegmatis_MC2_155 N-----------GTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------ESFGSSMGSHGAAG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 AGAGGNGGSATG--VGNGGNGGDGGNGGDGGNG-----APGGFGGGAGAG Rv3508|M.tuberculosis_H37Rv AGAGGNGGSATG--VGNGGNGGDGGNGGDGGNG-----APGGFGGGAGAG MUL_4367|M.ulcerans_Agy99 GGIGGDGK--------LGGFGGDGGDGGDGGFG-----VIGGQGGGGGFG Mflv_5091|M.gilvum_PYR-GCK GGAGGGGG---------AGGSGAGGAGGAGGSG-----GSGGSGGSGGSG Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGG---------AGGSGTGGAGGAGGSG-----GSGGSGGAGGSG MMAR_4602|M.marinum_M GGGGGGGAVAQSSFANNGGPGRDGADGGDGGAGGFIIGTYGGNGGGAAGA MSMEG_0868|M.smegmatis_MC2_155 GGDGSEPG---------PGGNGAGGAGGNGGTG-------GTTAGGSGNG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------TGFEAQGHAQGHASET-----AHTTLPGAEHH- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb3538|M.bovis_AF2122/97 GLGGSGAGGGTDGDDGNGGSPGTDGS Rv3508|M.tuberculosis_H37Rv GLGGSGAGGGTDGDDGNGGSPGTDGS MUL_4367|M.ulcerans_Agy99 GLGGTGAGG-APSDKGINGEPGNPG- Mflv_5091|M.gilvum_PYR-GCK GAAG-------DSDD----------- Mvan_1264|M.vanbaalenii_PYR-1 GAAG-------DSD------------ MMAR_4602|M.marinum_M GGGGGAAFNVVATAQGGQGQSG---- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu -------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------- MLBr_01183|M.leprae_Br4923 -------------------------- MAV_4827|M.avium_104 --------------------------